A randomised double-blind, placebo-controlled, long-term extension study of the efficacy, safety and tolerability of fixed-dose combinations of aclidinium/formoterol or monotherapy in the treatment of chronic obstructive pulmonary disease
D'Urzo, Anthony, Rennard, Stephen, Kerwin, Edward, Donohue, James F, Lei, Alejhandra, Molins, Eduard, Leselbaum, Anne
Published in Respiratory medicine (01.04.2017)
Published in Respiratory medicine (01.04.2017)
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Journal Article
Use of aclidinium did not increase the risk of death in a noninterventional cohort study in the Clinical Practice Research Datalink (CPRD), United Kingdom
Rebordosa, Cristina, Aguado, Jaume, Plana, Estel, Thomas, Steven, Frances, Ana, Lei, Alejhandra, García-Gil, Esther, Nuevo, Javier, Perez-Gutthann, Susana, Castellsague, Jordi
Published in Respiratory medicine (01.06.2019)
Published in Respiratory medicine (01.06.2019)
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Navafenterol (AZD8871) in patients with COPD: a randomized, double-blind, phase I study evaluating safety and pharmacodynamics of single doses of this novel, inhaled, long-acting, dual-pharmacology bronchodilator
Singh, Dave, Balaguer, Victor, Astbury, Carol, Wählby-Hamrén, Ulrika, Jimenez, Eulalia, Seoane, Beatriz, Villarroel, Cristina, Lei, Alejhandra, Aggarwal, Ajay, Psallidas, Ioannis
Published in Respiratory research (09.09.2020)
Published in Respiratory research (09.09.2020)
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Navafenterol (AZD8871) in healthy volunteers: safety, tolerability and pharmacokinetics of multiple ascending doses of this novel inhaled, long-acting, dual-pharmacology bronchodilator, in two phase I, randomised, single-blind, placebo-controlled studies
Balaguer, Victor, Albayaty, Muna, Jimenez, Eulalia, Wählby-Hamrén, Ulrika, Astbury, Carol, Seoane, Beatriz, Malice, Marie-Pierre, Lei, Alejhandra, Aggarwal, Ajay, Psallidas, Ioannis
Published in Respiratory research (09.09.2020)
Published in Respiratory research (09.09.2020)
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A Phase 1, Randomized, Double‐Blind, Placebo‐Controlled, Single Ascending Dose Study to Evaluate the Pharmacokinetics, Immunogenicity, Safety, and Tolerability After Subcutaneous Administration of Tozorakimab in Healthy Chinese Participants
Li, Yunfei, Zhang, Hua, Pandya, Hitesh, Miao, Liyan, Reid, Fred, Jimenez, Eulalia, Sadiq, Muhammad Waqas, Moate, Rachel, Lei, Alejhandra, Zhou, Xiao‐Hong, Kell, Chris, Ding, Junjie, Zhang, Guanlin, Zhao, Lina, Ge, Xiaoyun
Published in Clinical pharmacology in drug development (01.06.2024)
Published in Clinical pharmacology in drug development (01.06.2024)
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AZD9567 versus prednisolone in patients with active rheumatoid arthritis: A phase IIa, randomized, double‐blind, efficacy, and safety study
Laar, Jacob M., Lei, Alejhandra, Safy‐Khan, Mary, Almquist, Joachim, Belfield, Graham, Edman, Karl, Öberg, Lisa, Angermann, Bastian R., Dillmann, Inken, Berntsson, Pia, Etal, Damla, Dainty, Ian, Astbury, Carol, Belvisi, Maria G., Nemes, Szilárd, Platt, Adam, Prothon, Susanne, Samuelsson, Sara, Svanberg, Petter, Keen, Christina, Jacobs, J. W. G., Kaan, Ellen, Tubergen, Astrid, Hermans, Kasper, Vonkeman, Harald, Moghadam, Marjan Ghiti, Gjertsson, Inger, Ekwall, Anna‐Karin, Kapetanovic, Meliha, Einarsson, Jon Thorkell, Axelsson, Lena T., Olsson, Richard, Myrbäck, Tove Hegelund, Taib, Ziad, Vikman, Kerstin
Published in Clinical and translational science (01.12.2023)
Published in Clinical and translational science (01.12.2023)
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A Randomized Phase I Study of the Anti‐Interleukin‐33 Antibody Tozorakimab in Healthy Adults and Patients With Chronic Obstructive Pulmonary Disease
Reid, Fred, Singh, Dave, Albayaty, Muna, Moate, Rachel, Jimenez, Eulalia, Sadiq, Muhammad Waqas, Howe, David, Gavala, Monica, Killick, Helen, Williams, Adam, Krishnan, Surekha, Godwood, Alex, Shukla, Animesh, Hewitt, Lisa, Lei, Alejhandra, Kell, Chris, Pandya, Hitesh, Newcombe, Paul, White, Nicholas, Scott, Ian C., Cohen, E. Suzanne
Published in Clinical pharmacology and therapeutics (01.03.2024)
Published in Clinical pharmacology and therapeutics (01.03.2024)
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Journal Article
The novel bronchodilator navafenterol: a phase 2a, multicentre, randomised, double-blind, placebo-controlled crossover trial in COPD
Singh, Dave, Beier, Jutta, Astbury, Carol, Belvisi, Maria G, Da Silva, Carla A, Jauhiainen, Alexandra, Jimenez, Eulalia, Lei, Alejhandra, Necander, Sofia, Smith, Jaclyn A, Wählby Hamrén, Ulrika, Xin, Wenjing, Psallidas, Ioannis
Published in The European respiratory journal (01.04.2022)
Published in The European respiratory journal (01.04.2022)
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Journal Article
A Randomized Trial of Dual-Acting Bronchodilator AZD8871 for Chronic Obstructive Pulmonary Disease
Singh, Dave, Fuhr, Rainard, Jimenez, Lali, Wählby Hamrén, Ulrika, Jauhiainen, Alexandra, Malice, Marie-Pierre, Balaguer, Victor, Lei, Alejhandra, Aggarwal, Ajay, Astbury, Carol, Psallidas, Ioannis
Published in American journal of respiratory and critical care medicine (15.05.2019)
Published in American journal of respiratory and critical care medicine (15.05.2019)
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Journal Article
Characteristics of New Users of Aclidinium Bromide, Aclidinium/Formoterol, and Other COPD Medications in the United Kingdom, Denmark, and Germany
Rivero-Ferrer, Elena, Olesen, Morten, Plana, Estel, Aguado, Jaume, Saigí-Morgui, Núria, Rubino, Annalisa, Daoud, Sami Z., Lei, Alejhandra, Perez-Gutthann, Susana, Schink, Tania, Kristiansen, Nina Sahlertz, Hallas, Jesper, Pottegård, Anton, Rebordosa, Cristina
Published in Clinical drug investigation (01.04.2022)
Published in Clinical drug investigation (01.04.2022)
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Risk Assessment of Acute Myocardial Infarction and Stroke Associated with Long-Acting Muscarinic Antagonists, Alone or in Combination, versus Long-Acting beta2-Agonists
Rebordosa, Cristina, Plana, Estel, Rubino, Annalisa, Aguado, Jaume, Martinez, David, Lei, Alejhandra, Daoud, Sami, Saigi-Morgui, Nuria, Perez-Gutthann, Susana, Rivero-Ferrer, Elena
Published in International journal of chronic obstructive pulmonary disease (01.01.2022)
Published in International journal of chronic obstructive pulmonary disease (01.01.2022)
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A Cohort Study to Evaluate the Risk of Hospitalisation for Congestive Heart Failure Associated with the Use of Aclidinium and Other Chronic Obstructive Pulmonary Disease Medications in the UK Clinical Practice Research Datalink
Rebordosa, Cristina, Plana, Estel, Rubino, Annalisa, Aguado, Jaume, Lei, Alejhandra, Daoud, Sami, Saigi-Morgui, Nuria, Perez-Gutthann, Susana, Rivero-Ferrer, Elena
Published in International journal of chronic obstructive pulmonary disease (01.01.2021)
Published in International journal of chronic obstructive pulmonary disease (01.01.2021)
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