The role of mucus on drug transport and its potential to affect therapeutic outcomes
Murgia, Xabier, Loretz, Brigitta, Hartwig, Olga, Hittinger, Marius, Lehr, Claus-Michael
Published in Advanced drug delivery reviews (15.01.2018)
Published in Advanced drug delivery reviews (15.01.2018)
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Journal Article
Tobramycin Liquid Crystal Nanoparticles Eradicate Cystic Fibrosis‐Related Pseudomonas aeruginosa Biofilms
Thorn, Chelsea R., Carvalho‐Wodarz, Cristiane de Souza, Horstmann, Justus C., Lehr, Claus‐Michael, Prestidge, Clive A., Thomas, Nicky
Published in Small (Weinheim an der Bergstrasse, Germany) (01.06.2021)
Published in Small (Weinheim an der Bergstrasse, Germany) (01.06.2021)
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Journal Article
Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane
Zamprogno, Pauline, Wüthrich, Simon, Achenbach, Sven, Thoma, Giuditta, Stucki, Janick D., Hobi, Nina, Schneider-Daum, Nicole, Lehr, Claus-Michael, Huwer, Hanno, Geiser, Thomas, Schmid, Ralph A., Guenat, Olivier T.
Published in Communications biology (05.02.2021)
Published in Communications biology (05.02.2021)
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Journal Article
Nanoparticle Geometry and Surface Orientation Influence Mode of Cellular Uptake
Herd, Heather, Daum, Nicole, Jones, Arwyn T, Huwer, Hanno, Ghandehari, Hamidreza, Lehr, Claus-Michael
Published in ACS nano (26.03.2013)
Published in ACS nano (26.03.2013)
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Journal Article
Cell‐Derived Vesicles for Antibiotic Delivery—Understanding the Challenges of a Biogenic Carrier System
Heinrich, Eilien, Hartwig, Olga, Walt, Christine, Kardani, Arefeh, Koch, Marcus, Jahromi, Leila Pourtalebi, Hoppstädter, Jessica, Kiemer, Alexandra K., Loretz, Brigitta, Lehr, Claus‐Michael, Fuhrmann, Gregor
Published in Small (Weinheim an der Bergstrasse, Germany) (01.06.2023)
Published in Small (Weinheim an der Bergstrasse, Germany) (01.06.2023)
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Journal Article
Medium throughput breathing human primary cell alveolus-on-chip model
Stucki, Janick D., Hobi, Nina, Galimov, Artur, Stucki, Andreas O., Schneider-Daum, Nicole, Lehr, Claus-Michael, Huwer, Hanno, Frick, Manfred, Funke-Chambour, Manuela, Geiser, Thomas, Guenat, Olivier T.
Published in Scientific reports (25.09.2018)
Published in Scientific reports (25.09.2018)
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Journal Article
Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P. aeruginosa Biofilm Infections
Ho, Duy‐Khiet, Murgia, Xabier, De Rossi, Chiara, Christmann, Rebekka, Hüfner de Mello Martins, Antonio G., Koch, Marcus, Andreas, Anastasia, Herrmann, Jennifer, Müller, Rolf, Empting, Martin, Hartmann, Rolf W., Desmaele, Didier, Loretz, Brigitta, Couvreur, Patrick, Lehr, Claus‐Michael
Published in Angewandte Chemie International Edition (22.06.2020)
Published in Angewandte Chemie International Edition (22.06.2020)
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Journal Article
Extracellular vesicles protect glucuronidase model enzymes during freeze-drying
Frank, Julia, Richter, Maximilian, de Rossi, Chiara, Lehr, Claus-Michael, Fuhrmann, Kathrin, Fuhrmann, Gregor
Published in Scientific reports (17.08.2018)
Published in Scientific reports (17.08.2018)
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Journal Article
Drug delivery to the inflamed intestinal mucosa – targeting technologies and human cell culture models for better therapies of IBD
Hartwig, Olga, Shetab Boushehri, Maryam A., Shalaby, Karim S., Loretz, Brigitta, Lamprecht, Alf, Lehr, Claus-Michael
Published in Advanced drug delivery reviews (01.08.2021)
Published in Advanced drug delivery reviews (01.08.2021)
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Journal Article
A New Class of Polyion Complex Vesicles (PIC‐somes) to Improve Antimicrobial Activity of Tobramycin in Pseudomonas Aeruginosa Biofilms
Yildirim, Turgay, Bali, Aghiad, Koch, Marcus, Paul, Pascal, Latta, Lorenz, Schneider‐Daum, Nicole, Gallei, Markus, Lehr, Claus‐Michael
Published in Small (Weinheim an der Bergstrasse, Germany) (01.10.2024)
Published in Small (Weinheim an der Bergstrasse, Germany) (01.10.2024)
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Journal Article
Soluplus® as an effective absorption enhancer of poorly soluble drugs in vitro and in vivo
Linn, Michael, Collnot, Eva-Maria, Djuric, Dejan, Hempel, Katja, Fabian, Eric, Kolter, Karl, Lehr, Claus-Michael
Published in European journal of pharmaceutical sciences (14.02.2012)
Published in European journal of pharmaceutical sciences (14.02.2012)
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Journal Article
Budesonide Loaded PLGA Nanoparticles for Targeting the Inflamed Intestinal Mucosa—Pharmaceutical Characterization and Fluorescence Imaging
Ali, Hussain, Weigmann, Benno, Collnot, Eva-Maria, Khan, Saeed Ahmad, Windbergs, Maike, Lehr, Claus-Michael
Published in Pharmaceutical research (01.05.2016)
Published in Pharmaceutical research (01.05.2016)
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Journal Article
Nano- and microscaled particles for drug targeting to inflamed intestinal mucosa—A first in vivo study in human patients
Schmidt, Carsten, Lautenschlaeger, Christian, Collnot, Eva-Maria, Schumann, Michael, Bojarski, Christian, Schulzke, Jörg-Dieter, Lehr, Claus-Michael, Stallmach, Andreas
Published in Journal of controlled release (28.01.2013)
Published in Journal of controlled release (28.01.2013)
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Journal Article
Selective follicular targeting by modification of the particle sizes
Patzelt, Alexa, Richter, Heike, Knorr, Fanny, Schäfer, Ulrich, Lehr, Claus-Michael, Dähne, Lars, Sterry, Wolfram, Lademann, Juergen
Published in Journal of controlled release (28.02.2011)
Published in Journal of controlled release (28.02.2011)
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Journal Article
Optical tweezers reveal relationship between microstructure and nanoparticle penetration of pulmonary mucus
Kirch, Julian, Schneider, Andreas, Abou, Bérengère, Hopf, Alexander, Schaefer, Ulrich F, Schneider, Marc, Schall, Christian, Wagner, Christian, Lehr, Claus-Michael
Published in Proceedings of the National Academy of Sciences - PNAS (06.11.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (06.11.2012)
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Journal Article
Bioinspired Liposomes for Oral Delivery of Colistin to Combat Intracellular Infections by Salmonella enterica
Menina, Sara, Eisenbeis, Janina, Kamal, Mohamed Ashraf M., Koch, Marcus, Bischoff, Markus, Gordon, Sarah, Loretz, Brigitta, Lehr, Claus‐Michael
Published in Advanced healthcare materials (01.09.2019)
Published in Advanced healthcare materials (01.09.2019)
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Journal Article
Yields and Immunomodulatory Effects of Pneumococcal Membrane Vesicles Differ with the Bacterial Growth Phase
Mehanny, Mina, Kroniger, Tobias, Koch, Marcus, Hoppstädter, Jessica, Becher, Dörte, Kiemer, Alexandra K., Lehr, Claus‐Michael, Fuhrmann, Gregor
Published in Advanced healthcare materials (01.03.2022)
Published in Advanced healthcare materials (01.03.2022)
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Journal Article