Mammalian brain glycoproteins exhibit diminished glycan complexity compared to other tissues
Williams, Sarah E., Noel, Maxence, Lehoux, Sylvain, Cetinbas, Murat, Xavier, Ramnik J., Sadreyev, Ruslan I., Scolnick, Edward M., Smoller, Jordan W., Cummings, Richard D., Mealer, Robert G.
Published in Nature communications (12.01.2022)
Published in Nature communications (12.01.2022)
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Journal Article
Cosmc controls B cell homing
Zeng, Junwei, Eljalby, Mahmoud, Aryal, Rajindra P., Lehoux, Sylvain, Stavenhagen, Kathrin, Kudelka, Matthew R., Wang, Yingchun, Wang, Jianmei, Ju, Tongzhong, von Andrian, Ulrich H., Cummings, Richard D.
Published in Nature communications (10.08.2020)
Published in Nature communications (10.08.2020)
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Journal Article
The schizophrenia risk locus in SLC39A8 alters brain metal transport and plasma glycosylation
Mealer, Robert G., Jenkins, Bruce G., Chen, Chia-Yen, Daly, Mark J., Ge, Tian, Lehoux, Sylvain, Marquardt, Thorsten, Palmer, Christopher D., Park, Julien H., Parsons, Patrick J., Sackstein, Robert, Williams, Sarah E., Cummings, Richard D., Scolnick, Edward M., Smoller, Jordan W.
Published in Scientific reports (04.08.2020)
Published in Scientific reports (04.08.2020)
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Journal Article
ST6Gal1 in plasma is dispensable for IgG sialylation
Oswald, Douglas M, Lehoux, Sylvain D, Zhou, Julie Y, Glendenning, Leandre M, Cummings, Richard D, Cobb, Brian A
Published in Glycobiology (Oxford) (18.08.2022)
Published in Glycobiology (Oxford) (18.08.2022)
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Journal Article
Glycosylation of Zika Virus is Important in Host-Virus Interaction and Pathogenic Potential
Routhu, Nanda Kishore, Lehoux, Sylvain D, Rouse, Emily A, Bidokhti, Mehdi R M, Giron, Leila B, Anzurez, Alitzel, Reid, St Patrick, Abdel-Mohsen, Mohamed, Cummings, Richard D, Byrareddy, Siddappa N
Published in International journal of molecular sciences (21.10.2019)
Published in International journal of molecular sciences (21.10.2019)
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Journal Article
Mucin glycans attenuate the virulence of Pseudomonas aeruginosa in infection
Wheeler, Kelsey M., Cárcamo-Oyarce, Gerardo, Turner, Bradley S., Dellos-Nolan, Sheri, Co, Julia Y., Lehoux, Sylvain, Cummings, Richard D., Wozniak, Daniel J., Ribbeck, Katharina
Published in Nature microbiology (01.12.2019)
Published in Nature microbiology (01.12.2019)
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Journal Article
N-Glycosylation affects the stability and barrier function of the MUC16 mucin
Taniguchi, Takazumi, Woodward, Ashley M., Magnelli, Paula, McColgan, Nicole M., Lehoux, Sylvain, Jacobo, Sarah Melissa P., Mauris, Jérôme, Argüeso, Pablo
Published in The Journal of biological chemistry (30.06.2017)
Published in The Journal of biological chemistry (30.06.2017)
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Journal Article
PDX-derived organoids model in vivo drug response and secrete biomarkers
Huang, Ling, Bockorny, Bruno, Paul, Indranil, Akshinthala, Dipikaa, Frappart, Pierre-Oliver, Gandarilla, Omar, Bose, Arindam, Sanchez-Gonzalez, Veronica, Rouse, Emily E, Lehoux, Sylvain D, Pandell, Nicole, Lim, Christine M, Clohessy, John G, Grossman, Joseph, Gonzalez, Raul, Del Pino, Sofia Perea, Daaboul, George, Sawhney, Mandeep S, Freedman, Steven D, Kleger, Alexander, Cummings, Richard D, Emili, Andrew, Muthuswamy, Lakshmi B, Hidalgo, Manuel, Muthuswamy, Senthil K
Published in JCI insight (05.11.2020)
Published in JCI insight (05.11.2020)
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Journal Article
Targeting altered glycosylation in secreted tumor glycoproteins for broad cancer detection
Kudelka, Matthew R, Gu, Wei, Matsumoto, Yasuyuki, Ju, Tongzhong, Barnes II, Richard H, Kardish, Robert J, Heimburg-Molinaro, Jamie, Lehoux, Sylvain, Zeng, Junwei, Cohen, Cynthia, Robinson, Brian S, Shah, Kinjal S, Chaikof, Elliot L, Stowell, Sean R, Cummings, Richard D
Published in Glycobiology (Oxford) (14.08.2023)
Published in Glycobiology (Oxford) (14.08.2023)
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Journal Article
Tn and sialyl-Tn antigens, aberrant O-glycomics as human disease markers
Ju, Tongzhong, Wang, Yingchun, Aryal, Rajindra P., Lehoux, Sylvain D., Ding, Xiaokun, Kudelka, Matthew R., Cutler, Christopher, Zeng, Junwei, Wang, Jianmei, Sun, Xiaodong, Heimburg-Molinaro, Jamie, Smith, David F., Cummings, Richard D.
Published in Proteomics. Clinical applications (01.10.2013)
Published in Proteomics. Clinical applications (01.10.2013)
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Journal Article
Aberrantly glycosylated IgG elicits pathogenic signaling in podocytes and signifies lupus nephritis
Bhargava, Rhea, Lehoux, Sylvain, Maeda, Kayaho, Tsokos, Maria G, Krishfield, Suzanne, Ellezian, Lena, Pollak, Martin, Stillman, Isaac E, Cummings, Richard D, Tsokos, George C
Published in JCI insight (10.05.2021)
Published in JCI insight (10.05.2021)
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Journal Article
Evidence of Alternative Modes of B Cell Activation Involving Acquired Fab Regions of N‐Glycosylation in Antibody‐Secreting Cells Infiltrating the Labial Salivary Glands of Patients With Sjögren’s Syndrome
Koelsch, Kristi A., Cavett, Joshua, Smith, Kenneth, Moore, Jacen S., Lehoux, Sylvain D., Jia, Nan, Mather, Tim, Quadri, Syed M. S., Rasmussen, Astrid, Kaufman, C. Erick, Lewis, David M., Radfar, Lida, Scordino, Teresa A., Lessard, Christopher J., Kurien, Biji T., Cummings, Richard D., James, Judith A., Sivils, Kathy L., Farris, A. Darise, Scofield, R. Hal
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2018)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2018)
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Journal Article
GD3 synthase overexpression enhances proliferation and migration of MDA-MB-231 breast cancer cells
Cazet, Aurélie, Groux-Degroote, Sophie, Teylaert, Béatrice, Kwon, Kyung-Min, Lehoux, Sylvain, Slomianny, Christian, Kim, Cheorl-Ho, Le Bourhis, Xuefen, Delannoy, Philippe
Published in Biological chemistry (01.07.2009)
Published in Biological chemistry (01.07.2009)
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Journal Article
Transcriptional regulation of the human ST6GAL2 gene in cerebral cortex and neuronal cells
Lehoux, Sylvain, Groux-Degroote, Sophie, Cazet, Aurélie, Dhaenens, Claire-Marie, Maurage, Claude-Alain, Caillet-Boudin, Marie-Laure, Delannoy, Philippe, Krzewinski-Recchi, Marie-Ange
Published in Glycoconjugate journal (01.01.2010)
Published in Glycoconjugate journal (01.01.2010)
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Journal Article
IL-6 and IL-8 increase the expression of glycosyltransferases and sulfotransferases involved in the biosynthesis of sialylated and/or sulfated Lewisx epitopes in the human bronchial mucosa
Groux-Degroote, Sophie, Krzewinski-Recchi, Marie-Ange, Cazet, Aurélie, Vincent, Audrey, Lehoux, Sylvain, Lafitte, Jean-Jacques, Van Seuningen, Isabelle, Delannoy, Philippe
Published in Biochemical journal (15.02.2008)
Published in Biochemical journal (15.02.2008)
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Journal Article
Mucin Glycans Signal through the Sensor Kinase RetS to Inhibit Virulence-Associated Traits in Pseudomonas aeruginosa
Wang, Benjamin X., Wheeler, Kelsey M., Cady, Kyle C., Lehoux, Sylvain, Cummings, Richard D., Laub, Michael T., Ribbeck, Katharina
Published in Current biology (11.01.2021)
Published in Current biology (11.01.2021)
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Journal Article
Generation of fully functional hepatocyte-like organoids from human induced pluripotent stem cells mixed with Endothelial Cells
Pettinato, Giuseppe, Lehoux, Sylvain, Ramanathan, Rajesh, Salem, Mohamed M., He, Li-Xia, Muse, Oluwatoyosi, Flaumenhaft, Robert, Thompson, Melissa T., Rouse, Emily A., Cummings, Richard D., Wen, Xuejun, Fisher, Robert A.
Published in Scientific reports (20.06.2019)
Published in Scientific reports (20.06.2019)
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Journal Article
Regulation of neutrophil function by selective targeting of glycan epitopes expressed on the integrin CD11b/CD18
Kelm, Matthias, Lehoux, Sylvain, Azcutia, Veronica, Cummings, Richard D, Nusrat, Asma, Parkos, Charles A, Brazil, Jennifer C
Published in The FASEB journal (01.02.2020)
Published in The FASEB journal (01.02.2020)
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Journal Article
Mucin O-glycans are natural inhibitors of Candida albicans pathogenicity
Takagi, Julie, Aoki, Kazuhiro, Turner, Bradley S., Lamont, Sabrina, Lehoux, Sylvain, Kavanaugh, Nicole, Gulati, Megha, Valle Arevalo, Ashley, Lawrence, Travis J., Kim, Colin Y., Bakshi, Bhavya, Ishihara, Mayumi, Nobile, Clarissa J., Cummings, Richard D., Wozniak, Daniel J., Tiemeyer, Michael, Hevey, Rachel, Ribbeck, Katharina
Published in Nature chemical biology (01.07.2022)
Published in Nature chemical biology (01.07.2022)
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Journal Article
Inflammatory Stress Causes N-Glycan Processing Deficiency in Ocular Autoimmune Disease
Woodward, Ashley M., Lehoux, Sylvain, Mantelli, Flavio, Di Zazzo, Antonio, Brockhausen, Inka, Bonini, Stefano, Argüeso, Pablo
Published in The American journal of pathology (01.02.2019)
Published in The American journal of pathology (01.02.2019)
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Journal Article