Immune dysregulation in SHARPIN-deficient mice is dependent on CYLD-mediated cell death
Ang, Rosalind L., Chan, Mark, Legarda, Diana, Sundberg, John P., Sun, Shao-Cong, Gillespie, Virginia L., Chun, Nicholas, Heeger, Peter S., Xiong, Huabao, Lira, Sergio A., Ting, Adrian T.
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2021)
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Journal Article
Analysis of Necroptosis in Bone Marrow-Derived Macrophages
Legarda, Diana, Ting, Adrian T
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2018)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2018)
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Journal Article
CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN
Legarda, Diana, Justus, Scott J., Ang, Rosalind L., Rikhi, Nimisha, Li, Wenjing, Moran, Thomas M., Zhang, Jianke, Mizoguchi, Emiko, Zelic, Matija, Kelliher, Michelle A., Blander, J. Magarian, Ting, Adrian T.
Published in Cell reports (Cambridge) (14.06.2016)
Published in Cell reports (Cambridge) (14.06.2016)
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Journal Article
Reversal of CYLD phosphorylation as a novel therapeutic approach for adult T-cell leukemia/lymphoma (ATLL)
Xu, Xin, Kalac, Matko, Markson, Michael, Chan, Mark, Brody, Joshua D., Bhagat, Govind, Ang, Rosalind L., Legarda, Diana, Justus, Scott J., Liu, Feng, Li, Qingshan, Xiong, Huabao, Ting, Adrian T.
Published in Cell death & disease (05.02.2020)
Published in Cell death & disease (05.02.2020)
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Journal Article
NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1
O'Donnell, Marie Anne, Hase, Hidenori, Legarda, Diana, Ting, Adrian T
Published in PloS one (26.07.2012)
Published in PloS one (26.07.2012)
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Journal Article
SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis
Wang, Di, Lin, Yunkai, Xu, Feihong, Zhang, Hui, Zhu, Xiaoyan, Liu, Zhen, Hu, Yuan, Dong, Guanjun, Sun, Bingqi, Yu, Yanhong, Ma, Guoren, Tang, Zhigang, Legarda, Diana, Ting, Adrian, Liu, Yuan, Hou, Jia, Dong, Liwei, Xiong, Huabao
Published in EBioMedicine (01.11.2022)
Published in EBioMedicine (01.11.2022)
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Journal Article
One of Two Human Lactoferrin Variants Exhibits Increased Antibacterial and Transcriptional Activation Activities and Is Associated with Localized Juvenile Periodontitis
VELLIYAGOUNDER, Kabilan, KAPLAN, Jeffrey B, FURGANG, David, LEGARDA, Diana, DIAMOND, Gill, PARKIN, Ruth E, FINE, Daniel H
Published in Infection and Immunity (01.11.2003)
Published in Infection and Immunity (01.11.2003)
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Journal Article
B Cell Maturation Antigen, the Receptor for a Proliferation-Inducing Ligand and B Cell-Activating Factor of the TNF Family, Induces Antigen Presentation in B Cells
Yang, Min, Hase, Hidenori, Legarda-Addison, Diana, Varughese, Leena, Seed, Brian, Ting, Adrian T
Published in The Journal of immunology (1950) (01.09.2005)
Published in The Journal of immunology (1950) (01.09.2005)
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Journal Article
The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response
Friedman, Constantin S, O'Donnell, Marie Anne, Legarda-Addison, Diana, Ng, Aylwin, Cárdenas, Washington B, Yount, Jacob S, Moran, Thomas M, Basler, Christopher F, Komuro, Akihiko, Horvath, Curt M, Xavier, Ramnik, Ting, Adrian T
Published in EMBO reports (01.09.2008)
Published in EMBO reports (01.09.2008)
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Journal Article
Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death
Taft, Justin, Markson, Michael, Legarda, Diana, Patel, Roosheel, Chan, Mark, Malle, Louise, Richardson, Ashley, Gruber, Conor, Martín-Fernández, Marta, Mancini, Grazia M.S., van Laar, Jan A.M., van Pelt, Philomine, Buta, Sofija, Wokke, Beatrijs H.A., Sabli, Ira K.D., Sancho-Shimizu, Vanessa, Chavan, Pallavi Pimpale, Schnappauf, Oskar, Khubchandani, Raju, Cüceoğlu, Müşerref Kasap, Özen, Seza, Kastner, Daniel L., Ting, Adrian T., Aksentijevich, Ivona, Hollink, Iris H.I. M., Bogunovic, Dusan
Published in Cell (19.08.2021)
Published in Cell (19.08.2021)
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Journal Article
Analysis of CYLD Proteolysis by CASPASE 8 in Bone Marrow-Derived Macrophages
Legarda, Diana, Ting, Adrian T
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2018)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2018)
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Journal Article
Single-Cell and Population-Level Analyses Using Real-Time Kinetic Labeling Couples Proliferation and Cell Death Mechanisms
Gelles, Jesse D., Mohammed, Jarvier N., Santos, Luis C., Legarda, Diana, Ting, Adrian T., Chipuk, Jerry E.
Published in Developmental cell (21.10.2019)
Published in Developmental cell (21.10.2019)
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Journal Article
Production of Vascular Endothelial Growth Factor by Murine Macrophages
Xiong, Ming, Elson, Genie, Legarda, Diana, Leibovich, Samuel Joseph
Published in The American journal of pathology (01.08.1998)
Published in The American journal of pathology (01.08.1998)
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Journal Article
Interleukin-1β-induced IRAK1 ubiquitination is required for TH-GM-CSF cell differentiation in T cell-mediated inflammation
Hu, Yuan, Xu, Feihong, Zhang, Ruihua, Legarda, Diana, Dai, Jun, Wang, Di, Li, Heyu, Zhang, Yao, Xue, Qingjie, Dong, Guanjun, Zhang, Hui, Lu, Chang, Mortha, Arthur, Liu, Jianguo, Cravedi, Paolo, Ting, Adrian, Li, Liwu, Qi, Chen-feng, Pierce, Susan, Merad, Miriam, Heeger, Peter, Xiong, Huabao
Published in Journal of autoimmunity (01.08.2019)
Published in Journal of autoimmunity (01.08.2019)
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Journal Article
Interleukin-1β-induced IRAK1 ubiquitination is required for T H -GM-CSF cell differentiation in T cell-mediated inflammation
Hu, Yuan, Xu, Feihong, Zhang, Ruihua, Legarda, Diana, Dai, Jun, Wang, Di, Li, Heyu, Zhang, Yao, Xue, Qingjie, Dong, Guanjun, Zhang, Hui, Lu, Chang, Mortha, Arthur, Liu, Jianguo, Cravedi, Paolo, Ting, Adrian, Li, Liwu, Qi, Chen-Feng, Pierce, Susan, Merad, Miriam, Heeger, Peter, Xiong, Huabao
Published in Journal of autoimmunity (01.08.2019)
Published in Journal of autoimmunity (01.08.2019)
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