pyseer: a comprehensive tool for microbial pangenome-wide association studies
Lees, John A, Galardini, Marco, Bentley, Stephen D, Weiser, Jeffrey N, Corander, Jukka
Published in Bioinformatics (15.12.2018)
Published in Bioinformatics (15.12.2018)
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Journal Article
Producing polished prokaryotic pangenomes with the Panaroo pipeline
Tonkin-Hill, Gerry, MacAlasdair, Neil, Ruis, Christopher, Weimann, Aaron, Horesh, Gal, Lees, John A., Gladstone, Rebecca A., Lo, Stephanie, Beaudoin, Christopher, Floto, R. Andres, Frost, Simon D.W., Corander, Jukka, Bentley, Stephen D., Parkhill, Julian
Published in Genome Biology (22.07.2020)
Published in Genome Biology (22.07.2020)
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Journal Article
Fast hierarchical Bayesian analysis of population structure
Tonkin-Hill, Gerry, Lees, John A, Bentley, Stephen D, Frost, Simon D W, Corander, Jukka
Published in Nucleic acids research (20.06.2019)
Published in Nucleic acids research (20.06.2019)
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Journal Article
Sequence element enrichment analysis to determine the genetic basis of bacterial phenotypes
Lees, John A., Vehkala, Minna, Välimäki, Niko, Harris, Simon R., Chewapreecha, Claire, Croucher, Nicholas J., Marttinen, Pekka, Davies, Mark R., Steer, Andrew C., Tong, Steven Y. C., Honkela, Antti, Parkhill, Julian, Bentley, Stephen D., Corander, Jukka
Published in Nature communications (16.09.2016)
Published in Nature communications (16.09.2016)
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Journal Article
Immune exclusion by naturally acquired secretory IgA against pneumococcal pilus-1
Binsker, Ulrike, Lees, John A, Hammond, Alexandria J, Weiser, Jeffrey N
Published in The Journal of clinical investigation (01.02.2020)
Published in The Journal of clinical investigation (01.02.2020)
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Journal Article
Apparent nosocomial adaptation of Enterococcus faecalis predates the modern hospital era
Pöntinen, Anna K., Top, Janetta, Arredondo-Alonso, Sergio, Tonkin-Hill, Gerry, Freitas, Ana R., Novais, Carla, Gladstone, Rebecca A., Pesonen, Maiju, Meneses, Rodrigo, Pesonen, Henri, Lees, John A., Jamrozy, Dorota, Bentley, Stephen D., Lanza, Val F., Torres, Carmen, Peixe, Luisa, Coque, Teresa M., Parkhill, Julian, Schürch, Anita C., Willems, Rob J. L., Corander, Jukka
Published in Nature communications (09.03.2021)
Published in Nature communications (09.03.2021)
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Journal Article
Key epidemiological drivers and impact of interventions in the 2020 SARS-CoV-2 epidemic in England
Knock, Edward S, Whittles, Lilith K, Lees, John A, Perez-Guzman, Pablo N, Verity, Robert, FitzJohn, Richard G, Gaythorpe, Katy A M, Imai, Natsuko, Hinsley, Wes, Okell, Lucy C, Rosello, Alicia, Kantas, Nikolas, Walters, Caroline E, Bhatia, Sangeeta, Watson, Oliver J, Whittaker, Charlie, Cattarino, Lorenzo, Boonyasiri, Adhiratha, Djaafara, Bimandra A, Fraser, Keith, Fu, Han, Wang, Haowei, Xi, Xiaoyue, Donnelly, Christl A, Jauneikaite, Elita, Laydon, Daniel J, White, Peter J, Ghani, Azra C, Ferguson, Neil M, Cori, Anne, Baguelin, Marc
Published in Science Translational Medicine (14.07.2021)
Published in Science Translational Medicine (14.07.2021)
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Journal Article
Web Resource
Genome-wide identification of lineage and locus specific variation associated with pneumococcal carriage duration
Lees, John A, Croucher, Nicholas J, Goldblatt, David, Nosten, François, Parkhill, Julian, Turner, Claudia, Turner, Paul, Bentley, Stephen D
Published in eLife (25.07.2017)
Published in eLife (25.07.2017)
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Journal Article
Leveraging community mortality indicators to infer COVID-19 mortality and transmission dynamics in Damascus, Syria
Watson, Oliver J., Alhaffar, Mervat, Mehchy, Zaki, Whittaker, Charles, Akil, Zack, Brazeau, Nicholas F., Cuomo-Dannenburg, Gina, Hamlet, Arran, Thompson, Hayley A., Baguelin, Marc, FitzJohn, Richard G., Knock, Edward, Lees, John A., Whittles, Lilith K., Mellan, Thomas, Winskill, Peter, Howard, Natasha, Clapham, Hannah, Checchi, Francesco, Ferguson, Neil, Ghani, Azra, Beals, Emma, Walker, Patrick
Published in Nature communications (22.04.2021)
Published in Nature communications (22.04.2021)
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Journal Article
Impact of vaccinations, boosters and lockdowns on COVID-19 waves in French Polynesia
Chapman, Lloyd A. C., Aubry, Maite, Maset, Noémie, Russell, Timothy W., Knock, Edward S., Lees, John A., Mallet, Henri-Pierre, Cao-Lormeau, Van-Mai, Kucharski, Adam J.
Published in Nature communications (13.11.2023)
Published in Nature communications (13.11.2023)
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Journal Article
Inter-species gene flow drives ongoing evolution of Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis
Xie, Ouli, Morris, Jacqueline M., Hayes, Andrew J., Towers, Rebecca J., Jespersen, Magnus G., Lees, John A., Ben Zakour, Nouri L., Berking, Olga, Baines, Sarah L., Carter, Glen P., Tonkin-Hill, Gerry, Schrieber, Layla, McIntyre, Liam, Lacey, Jake A., James, Taylah B., Sriprakash, Kadaba S., Beatson, Scott A., Hasegawa, Tadao, Giffard, Phil, Steer, Andrew C., Batzloff, Michael R., Beall, Bernard W., Pinho, Marcos D., Ramirez, Mario, Bessen, Debra E., Dougan, Gordon, Bentley, Stephen D., Walker, Mark J., Currie, Bart J., Tong, Steven Y. C., McMillan, David J., Davies, Mark R.
Published in Nature communications (13.03.2024)
Published in Nature communications (13.03.2024)
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Journal Article
Emergence and dissemination of antimicrobial resistance in Escherichia coli causing bloodstream infections in Norway in 2002–17: a nationwide, longitudinal, microbial population genomic study
Gladstone, Rebecca A, McNally, Alan, Pöntinen, Anna K, Tonkin-Hill, Gerry, Lees, John A, Skytén, Kusti, Cléon, François, Christensen, Martin O K, Haldorsen, Bjørg C, Bye, Kristina K, Gammelsrud, Karianne W, Hjetland, Reidar, Kümmel, Angela, Larsen, Hege E, Lindemann, Paul Christoffer, Löhr, Iren H, Marvik, Åshild, Nilsen, Einar, Noer, Marie T, Simonsen, Gunnar S, Steinbakk, Martin, Tofteland, Ståle, Vattøy, Marit, Bentley, Stephen D, Croucher, Nicholas J, Parkhill, Julian, Johnsen, Pål J, Samuelsen, Ørjan, Corander, Jukka
Published in The Lancet. Microbe (01.07.2021)
Published in The Lancet. Microbe (01.07.2021)
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Journal Article
Pneumococcal genetic variability in age-dependent bacterial carriage
Kremer, Philip H C, Ferwerda, Bart, Bootsma, Hester J, Rots, Nienke Y, Wijmenga-Monsuur, Alienke J, Sanders, Elisabeth A M, Trzciński, Krzysztof, Wyllie, Anne L, Turner, Paul, van der Ende, Arie, Brouwer, Matthijs C, Bentley, Stephen D, van de Beek, Diederik, Lees, John A
Published in eLife (26.07.2022)
Published in eLife (26.07.2022)
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Journal Article
Pneumococcal capsule blocks protection by immunization with conserved surface proteins
Zangari, Tonia, Zafar, M. Ammar, Lees, John A., Abruzzo, Annie R., Bee, Gavyn Chern Wei, Weiser, Jeffrey N.
Published in npj vaccines (20.12.2021)
Published in npj vaccines (20.12.2021)
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Journal Article
Genetic Variation in Neisseria meningitidis Does Not Influence Disease Severity in Meningococcal Meningitis
Kremer, Philip H C, Lees, John A, Ferwerda, Bart, van de Ende, Arie, Brouwer, Matthijs C, Bentley, Stephen D, van de Beek, Diederik
Published in Frontiers in medicine (11.11.2020)
Published in Frontiers in medicine (11.11.2020)
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Journal Article
SuperDCA for genome-wide epistasis analysis
Puranen, Santeri, Pesonen, Maiju, Pensar, Johan, Xu, Ying Ying, Lees, John A, Bentley, Stephen D, Croucher, Nicholas J, Corander, Jukka
Published in Microbial genomics (01.06.2018)
Published in Microbial genomics (01.06.2018)
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Journal Article
Fast and flexible bacterial genomic epidemiology with PopPUNK
Lees, John A, Harris, Simon R, Tonkin-Hill, Gerry, Gladstone, Rebecca A, Lo, Stephanie W, Weiser, Jeffrey N, Corander, Jukka, Bentley, Stephen D, Croucher, Nicholas J
Published in Genome research (01.02.2019)
Published in Genome research (01.02.2019)
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Journal Article