Emerging Mechanisms by which EMT Programs Control Stemness
Wilson, Molly M, Weinberg, Robert A, Lees, Jacqueline A, Guen, Vincent J
Published in Trends in cancer (01.09.2020)
Published in Trends in cancer (01.09.2020)
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EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and Hedgehog signaling
Guen, Vincent J., Chavarria, Tony E., Kröger, Cornelia, Ye, Xin, Weinberg, Robert A., Lees, Jacqueline A.
Published in Proceedings of the National Academy of Sciences - PNAS (05.12.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (05.12.2017)
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Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma
Braun, Christian J., Stanciu, Monica, Boutz, Paul L., Patterson, Jesse C., Calligaris, David, Higuchi, Fumi, Neupane, Rachit, Fenoglio, Silvia, Cahill, Daniel P., Wakimoto, Hiroaki, Agar, Nathalie Y.R., Yaffe, Michael B., Sharp, Phillip A., Hemann, Michael T., Lees, Jacqueline A.
Published in Cancer cell (09.10.2017)
Published in Cancer cell (09.10.2017)
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Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis
Mori, Munemasa, Hazan, Renin, Danielian, Paul S., Mahoney, John E., Li, Huijun, Lu, Jining, Miller, Emily S., Zhu, Xueliang, Lees, Jacqueline A., Cardoso, Wellington V.
Published in Nature communications (04.07.2017)
Published in Nature communications (04.07.2017)
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Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation
Nicolay, Brandon N, Danielian, Paul S, Kottakis, Filippos, Lapek, Jr, John D, Sanidas, Ioannis, Miles, Wayne O, Dehnad, Mantre, Tschöp, Katrin, Gierut, Jessica J, Manning, Amity L, Morris, Robert, Haigis, Kevin, Bardeesy, Nabeel, Lees, Jacqueline A, Haas, Wilhelm, Dyson, Nicholas J
Published in Genes & development (01.09.2015)
Published in Genes & development (01.09.2015)
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The retinoblastoma protein induces apoptosis directly at the mitochondria
Hilgendorf, Keren I, Leshchiner, Elizaveta S, Nedelcu, Simona, Maynard, Mindy A, Calo, Eliezer, Ianari, Alessandra, Walensky, Loren D, Lees, Jacqueline A
Published in Genes & development (01.05.2013)
Published in Genes & development (01.05.2013)
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Cell size is a determinant of stem cell potential during aging
Lengefeld, Jette, Cheng, Chia-Wei, Maretich, Pema, Blair, Marguerite, Hagen, Hannah, McReynolds, Melanie R, Sullivan, Emily, Majors, Kyra, Roberts, Christina, Kang, Joon Ho, Steiner, Joachim D, Miettinen, Teemu P, Manalis, Scott R, Antebi, Adam, Morrison, Sean J, Lees, Jacqueline A, Boyer, Laurie A, Yilmaz, Ömer H, Amon, Angelika
Published in Science advances (12.11.2021)
Published in Science advances (12.11.2021)
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Proapoptotic Function of the Retinoblastoma Tumor Suppressor Protein
Ianari, Alessandra, Natale, Tiziana, Calo, Eliezer, Ferretti, Elisabetta, Alesse, Edoardo, Screpanti, Isabella, Haigis, Kevin, Gulino, Alberto, Lees, Jacqueline A.
Published in Cancer cell (03.03.2009)
Published in Cancer cell (03.03.2009)
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Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage
Berman, Seth D, Calo, Eliezer, Landman, Allison S, Danielian, Paul S, Miller, Emily S, West, Julie C, Fonhoue, Borel Djouedjong, Caron, Alicia, Bronson, Roderick, Bouxsein, Mary L, Mukherjee, Siddhartha, Lees, Jacqueline A
Published in Proceedings of the National Academy of Sciences - PNAS (19.08.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (19.08.2008)
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Journal Article
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
Sansam, Christopher L, Cruz, Nelly M, Danielian, Paul S, Amsterdam, Adam, Lau, Melissa L, Hopkins, Nancy, Lees, Jacqueline A
Published in Genes & development (15.01.2010)
Published in Genes & development (15.01.2010)
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Proliferation and Tumorigenesis of a Murine Sarcoma Cell Line in the Absence of DICER1
Ravi, Arvind, Gurtan, Allan M., Kumar, Madhu S., Bhutkar, Arjun, Chin, Christine, Lu, Victoria, Lees, Jacqueline A., Jacks, Tyler, Sharp, Phillip A.
Published in Cancer cell (12.06.2012)
Published in Cancer cell (12.06.2012)
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Journal Article
Many ribosomal protein genes are cancer genes in zebrafish
Amsterdam, Adam, Sadler, Kirsten C, Lai, Kevin, Farrington, Sarah, Bronson, Roderick T, Lees, Jacqueline A, Hopkins, Nancy
Published in PLoS biology (01.05.2004)
Published in PLoS biology (01.05.2004)
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Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics
Aslanian, Aaron, Iaquinta, Phillip J, Verona, Raluca, Lees, Jacqueline A
Published in Genes & development (15.06.2004)
Published in Genes & development (15.06.2004)
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Journal Article
An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis
Wilson, Molly M, Callens, Céline, Le Gallo, Matthieu, Mironov, Svetlana, Ding, Qiong, Salamagnon, Amandine, Chavarria, Tony E, Viel, Roselyne, Peasah, Abena D, Bhutkar, Arjun, Martin, Sophie, Godey, Florence, Tas, Patrick, Kang, Hong Soon, Juin, Philippe P, Jetten, Anton M, Visvader, Jane E, Weinberg, Robert A, Attanasio, Massimo, Prigent, Claude, Lees, Jacqueline A, Guen, Vincent J
Published in Science advances (29.10.2021)
Published in Science advances (29.10.2021)
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