Curcumin suppresses oncogenicity of human colon cancer cells by covalently modifying the cysteine 67 residue of SIRT1
Lee, Yeon-Hwa, Song, Na-Young, Suh, Jinyoung, Kim, Do-Hee, Kim, Wonki, Ann, Jihyae, Lee, Jeewoo, Baek, Jeong-Heum, Na, Hye-Kyung, Surh, Young-Joon
Published in Cancer letters (01.09.2018)
Published in Cancer letters (01.09.2018)
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Dorsal Root Ganglion Neurons Innervating Skeletal Muscle Respond to Physiological Combinations of Protons, ATP, and Lactate Mediated by ASIC, P2X, and TRPV1
Light, Alan R, Hughen, Ronald W, Zhang, Jie, Rainier, Jon, Liu, Zhuqing, Lee, Jeewoo
Published in Journal of neurophysiology (01.09.2008)
Published in Journal of neurophysiology (01.09.2008)
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A novel HSP90 inhibitor targeting the C-terminal domain attenuates trastuzumab resistance in HER2-positive breast cancer
Park, Jung Min, Kim, Yoon-Jae, Park, Soeun, Park, Minsu, Farrand, Lee, Nguyen, Cong-Truong, Ann, Jihyae, Nam, Gibeom, Park, Hyun-Ju, Lee, Jeewoo, Kim, Ji Young, Seo, Jae Hong
Published in Molecular cancer (20.11.2020)
Published in Molecular cancer (20.11.2020)
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Discovery of indane propanamides as potent and selective TRPV1 antagonists
Ahn, Songyeon, Kim, Yong Soo, Kim, Myeong Seup, Ann, Jihyae, Ha, Heejin, Yoo, Young Dong, Kim, Young Ho, Blumberg, Peter M., Frank-Foltyn, Robert, Bahrenberg, Gregor, Stockhausen, Hannelore, Christoph, Thomas, Lee, Jeewoo
Published in Bioorganic & medicinal chemistry letters (01.02.2020)
Published in Bioorganic & medicinal chemistry letters (01.02.2020)
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Discovery of Dual TRPA1 and TRPV1 Antagonists as Novel Therapeutic Agents for Pain
Do, Nayeon, Zuo, Dongxu, Kim, Miri, Kim, Minseok, Ha, Hee-Jin, Blumberg, Peter M, Ann, Jihyae, Hwang, Sun Wook, Lee, Jeewoo
Published in Pharmaceuticals (Basel, Switzerland) (13.09.2024)
Published in Pharmaceuticals (Basel, Switzerland) (13.09.2024)
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Discovery of Novel Dual Adenosine A2A and A1 Receptor Antagonists with 1H-Pyrazolo[3,4-d]pyrimidin-6-amine Core Scaffold as Anti-Parkinson’s Disease Agents
Jung, Juyoung, Lee, Yoonsuk, Moon, An-Na, Ann, Jihyae, Jeong, Jin Ju, Do, Nayeon, Lee, Jeewoo
Published in Pharmaceuticals (Basel, Switzerland) (25.07.2022)
Published in Pharmaceuticals (Basel, Switzerland) (25.07.2022)
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Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer’s agents: Structure-activity relationship study of Arg-mimetic region
Ngo, Van T.H., Hoang, Van-Hai, Tran, Phuong-Thao, Ann, Jihyae, Cui, Minghua, Park, Gyungseo, Choi, Sun, Lee, Jiyoun, Kim, Hee, Ha, Hee-Jin, Choi, Kwanghyun, Kim, Young-Ho, Lee, Jeewoo
Published in Bioorganic & medicinal chemistry (01.03.2018)
Published in Bioorganic & medicinal chemistry (01.03.2018)
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Structure-activity relationship investigation of Phe-Arg mimetic region of human glutaminyl cyclase inhibitors
Ngo, Van T.H., Hoang, Van-Hai, Tran, Phuong-Thao, Van Manh, Nguyen, Ann, Jihyae, Kim, Eunhye, Cui, Minghua, Choi, Sun, Lee, Jiyoun, Kim, Hee, Ha, Hee-Jin, Choi, Kwanghyun, Kim, Young-Ho, Lee, Jeewoo
Published in Bioorganic & medicinal chemistry (23.07.2018)
Published in Bioorganic & medicinal chemistry (23.07.2018)
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Journal Article
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain
Rossino, Giacomo, Marra, Annamaria, Listro, Roberta, Peviani, Marco, Poggio, Elena, Curti, Daniela, Pellavio, Giorgia, Laforenza, Umberto, Dondio, Giulio, Schepmann, Dirk, Wünsch, Bernhard, Bedeschi, Martina, Marino, Noemi, Tesei, Anna, Ha, Hee-Jin, Kim, Young-Ho, Ann, Jihyae, Lee, Jeewoo, Linciano, Pasquale, Di Giacomo, Marcello, Rossi, Daniela, Collina, Simona
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2023)
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2023)
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Transient receptor potential vanilloid-1 (TRPV1) is a mediator of lung toxicity for coal fly ash particulate material
Deering-Rice, Cassandra E, Johansen, Mark E, Roberts, Jessica K, Thomas, Karen C, Romero, Erin G, Lee, Jeewoo, Yost, Garold S, Veranth, John M, Reilly, Christopher A
Published in Molecular pharmacology (01.03.2012)
Published in Molecular pharmacology (01.03.2012)
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The C-terminal HSP90 inhibitor NCT-58 kills trastuzumab-resistant breast cancer stem-like cells
Park, Soeun, Kim, Yoon-Jae, Park, Jung Min, Park, Minsu, Nam, Kee Dal, Farrand, Lee, Nguyen, Cong-Truong, La, Minh Thanh, Ann, Jihyae, Lee, Jeewoo, Kim, Ji Young, Seo, Jae Hong
Published in Cell death discovery (13.11.2021)
Published in Cell death discovery (13.11.2021)
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Journal Article
Structure–activity relationship of human glutaminyl cyclase inhibitors having an N-(5-methyl-1H-imidazol-1-yl)propyl thiourea template
Tran, Phuong-Thao, Hoang, Van-Hai, Thorat, Shivaji A., Kim, Sung Eun, Ann, Jihyae, Chang, Yu Jin, Nam, Dong Woo, Song, Hyundong, Mook-Jung, Inhee, Lee, Jiyoun, Lee, Jeewoo
Published in Bioorganic & medicinal chemistry (01.07.2013)
Published in Bioorganic & medicinal chemistry (01.07.2013)
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Journal Article
Structure-activity relationship of capsaicin analogs and transient receptor potential vanilloid 1-mediated human lung epithelial cell toxicity
Thomas, Karen C, Ethirajan, Manivannan, Shahrokh, Kiumars, Sun, Hao, Lee, Jeewoo, Cheatham, 3rd, Thomas E, Yost, Garold S, Reilly, Christopher A
Published in The Journal of pharmacology and experimental therapeutics (01.05.2011)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2011)
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Journal Article
Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury
Thomas, Karen C, Roberts, Jessica K, Deering-Rice, Cassandra E, Romero, Erin G, Dull, Randal O, Lee, Jeewoo, Yost, Garold S, Reilly, Christopher A
Published in American journal of physiology. Lung cellular and molecular physiology (01.01.2012)
Published in American journal of physiology. Lung cellular and molecular physiology (01.01.2012)
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Fine tuning of 4,6-bisphenyl-2-(3-alkoxyanilino)pyrimidine focusing on the activity-sensitive aminoalkoxy moiety for a therapeutically useful inhibitor of receptor for advanced glycation end products (RAGE)
Han, Young Taek, Kim, Kyeojin, Son, Dohyun, An, Hongchan, Kim, Hee, Lee, Jeeyeon, Park, Hyun-Ju, Lee, Jeewoo, Suh, Young-Ger
Published in Bioorganic & medicinal chemistry (01.02.2015)
Published in Bioorganic & medicinal chemistry (01.02.2015)
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Journal Article
2‑(3-Fluoro-4-methylsulfonylaminophenyl)propanamides as Potent Transient Receptor Potential Vanilloid 1 (TRPV1) Antagonists: Structure–Activity Relationships of 2‑Amino Derivatives in the N‑(6-Trifluoromethylpyridin-3-ylmethyl) C‑Region
Kim, Myeong Seop, Ryu, HyungChul, Kang, Dong Wook, Cho, Seong-Hee, Seo, Sejin, Park, Young Soo, Kim, Mi-Yeon, Kwak, Eun Joo, Kim, Yong Soo, Bhondwe, Rahul S, Kim, Ho Shin, Park, Seul-gi, Son, Karam, Choi, Sun, DeAndrea-Lazarus, Ian A, Pearce, Larry V, Blumberg, Peter M, Frank, Robert, Bahrenberg, Gregor, Stockhausen, Hannelore, Kögel, Babette Y, Schiene, Klaus, Christoph, Thomas, Lee, Jeewoo
Published in Journal of medicinal chemistry (11.10.2012)
Published in Journal of medicinal chemistry (11.10.2012)
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Journal Article
High Affinity Antagonists of the Vanilloid Receptor
Wang, Yun, Szabo, Tamas, Welter, Jacqueline D, Toth, Attila, Tran, Richard, Lee, Jiyoun, Kang, Sang Uk, Suh, Young-Ger, Blumberg, Peter M, Lee, Jeewoo
Published in Molecular pharmacology (01.10.2002)
Published in Molecular pharmacology (01.10.2002)
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