Discovery of N-(3-fluoro-4-methylsulfonamidomethylphenyl)urea as a potent TRPV1 antagonistic template
Ann, Jihyae, Sun, Wei, Zhou, Xing, Jung, Aeran, Baek, Jisoo, Lee, Sunho, Kim, Changhoon, Yoon, Suyoung, Hong, Sunhye, Choi, Sun, Turcios, Noe A., Herold, Brienna K.A., Esch, Timothy E., Lewin, Nancy E., Abramovitz, Adelle, Pearce, Larry V., Blumberg, Peter M., Lee, Jeewoo
Published in Bioorganic & medicinal chemistry letters (01.08.2016)
Published in Bioorganic & medicinal chemistry letters (01.08.2016)
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2-(3-Fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists: Structure activity relationships of the 2-oxy pyridine C-region
Thorat, Shivaji A., Kang, Dong Wook, Ryu, HyungChul, Kim, Myeong Seop, Kim, Ho Shin, Ann, Jihyae, Ha, Taehwan, Kim, Sung-Eun, Son, Karam, Choi, Sun, Blumberg, Peter M., Frank, Robert, Bahrenberg, Gregor, Schiene, Klaus, Christoph, Thomas, Lee, Jeewoo
Published in European journal of medicinal chemistry (01.06.2013)
Published in European journal of medicinal chemistry (01.06.2013)
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TRPV1 antagonist with high analgesic efficacy: 2-Thio pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides
Ha, Tae-Hwan, Ryu, HyungChul, Kim, Sung-Eun, Kim, Ho Shin, Ann, Jihyae, Tran, Phuong-Thao, Hoang, Van-Hai, Son, Karam, Cui, Minghua, Choi, Sun, Blumberg, Peter M., Frank, Robert, Bahrenberg, Gregor, Schiene, Klaus, Christoph, Thomas, Frormann, Sven, Lee, Jeewoo
Published in Bioorganic & medicinal chemistry (01.11.2013)
Published in Bioorganic & medicinal chemistry (01.11.2013)
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2-Sulfonamidopyridine C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists
Ann, Jihyae, Ki, Yooran, Yoon, Suyoung, Kim, Myeong Seop, Lee, Jung-Un, Kim, Changhoon, Lee, Sunho, Jung, Aeran, Baek, Jisoo, Hong, Sunhye, Choi, Sun, Pearce, Larry V., Esch, Timothy E., Turcios, Noe A., Lewin, Nancy E., Ogunjirin, Adebowale E., Herold, Brienna K.A., McCall, Anna K., Blumberg, Peter M., Lee, Jeewoo
Published in Bioorganic & medicinal chemistry (15.03.2016)
Published in Bioorganic & medicinal chemistry (15.03.2016)
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Pyridine C-region analogs of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists
Ryu, HyungChul, Seo, Sejin, Lee, Jee-Young, Ha, Tae-Hwan, Lee, Sunho, Jung, Aeran, Ann, Jihyae, Kim, Sung-Eun, Yoon, Suyoung, Hong, Mannkyu, Blumberg, Peter M., Frank-Foltyn, Robert, Bahrenberg, Gregor, Schiene, Klaus, Stockhausen, Hannelore, Christoph, Thomas, Frormann, Sven, Lee, Jeewoo
Published in European journal of medicinal chemistry (26.03.2015)
Published in European journal of medicinal chemistry (26.03.2015)
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Corrigendum to “Aminopropyl carbazole analogues as potent enhancers of neurogenesis” [Bioorg. Med. Chem. 21 (2013) 7165–7174]
Yoon, Hye Jin, Kong, Sun-Young, Park, Min-Hye, Cho, Yongsung, Kim, Sung-Eun, Shin, Jae-Yeon, Jung, Sunghye, Lee, Jiyoun, Farhanullah, Kim, Hyun-Jung, Lee, Jeewoo
Published in Bioorganic & medicinal chemistry (15.01.2014)
Published in Bioorganic & medicinal chemistry (15.01.2014)
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α-Substituted 2-(3-fluoro-4-methylsulfonamidophenyl)acetamides as potent TRPV1 antagonists
Tran, Phuong-Thao, Kim, Ho Shin, Ann, Jihyae, Kim, Sung-Eun, Kim, Changhoon, Hong, Mannkyu, Hoang, Van-Hai, Ngo, Van T.H., Hong, Sunhye, Cui, Minghua, Choi, Sun, Blumberg, Peter M., Frank-Foltyn, Robert, Bahrenberg, Gregor, Stockhausen, Hannelore, Christoph, Thomas, Lee, Jeewoo
Published in Bioorganic & medicinal chemistry letters (01.06.2015)
Published in Bioorganic & medicinal chemistry letters (01.06.2015)
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Discovery of a Small Molecule that Enhances Astrocytogenesis by Activation of STAT3, SMAD1/5/8, and ERK1/2 via Induction of Cytokines in Neural Stem Cells
Lee, Ha-Rim, Farhanullah, Lee, JiSoo, Jajoo, Rahul, Kong, Sun-Young, Shin, Jae-Yeon, Kim, Jae-Ouk, Lee, Jiyoun, Lee, Jeewoo, Kim, Hyun-Jung
Published in ACS chemical neuroscience (20.01.2016)
Published in ACS chemical neuroscience (20.01.2016)
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Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists
Ann, Jihyae, Jung, Aeran, Kim, Mi-Yeon, Kim, Hyuk-Min, Ryu, HyungChul, Kim, Sunjoo, Kang, Dong Wook, Hong, Sunhye, Cui, Minghua, Choi, Sun, Blumberg, Peter M., Frank-Foltyn, Robert, Bahrenberg, Gregor, Stockhausen, Hannelore, Christoph, Thomas, Lee, Jeewoo
Published in Bioorganic & medicinal chemistry (01.11.2015)
Published in Bioorganic & medicinal chemistry (01.11.2015)
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2-Alkyl/alkenyl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists
Ryu, HyungChul, Seo, Sejin, Cho, Seong-Hee, Kim, Ho Shin, Jung, Aeran, Kang, Dong Wook, Son, Karam, Cui, Minghua, Hong, Sun-hye, Sharma, Pankaz Kumar, Choi, Sun, Blumberg, Peter M., Frank-Foltyn, Robert, Bahrenberg, Gregor, Stockhausen, Hannelore, Schiene, Klaus, Christoph, Thomas, Frormann, Sven, Lee, Jeewoo
Published in Bioorganic & medicinal chemistry letters (15.08.2014)
Published in Bioorganic & medicinal chemistry letters (15.08.2014)
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Journal Article
A two-photon fluorescent probe for amyloid-β plaques in living miceElectronic supplementary information (ESI) available. See DOI: 10.1039/c2cc38570h
Heo, Cheol Ho, Kim, Kyung Ho, Kim, Hyung Joong, Baik, Sung Hoon, Song, Hyundong, Kim, Yong Soo, Lee, Jeewoo, Mook-jung, Inhee, Kim, Hwan Myung
Year of Publication 17.01.2013
Year of Publication 17.01.2013
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2-Aryl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists
Ryu, HyungChul, Seo, Sejin, Kim, Myeong Seop, Kim, Mi-Yeon, Kim, Ho Shin, Ann, Jihyae, Tran, Phuong-Thao, Hoang, Van-Hai, Byun, Jieun, Cui, Minghua, Son, Karam, Sharma, Pankaz Kumar, Choi, Sun, Blumberg, Peter M., Frank-Foltyn, Robert, Bahrenberg, Gregor, Koegel, Babette-Yvonne, Christoph, Thomas, Frormann, Sven, Lee, Jeewoo
Published in Bioorganic & medicinal chemistry letters (15.08.2014)
Published in Bioorganic & medicinal chemistry letters (15.08.2014)
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Journal Article
α-Methylated simplified resiniferatoxin (sRTX) thiourea analogues as potent and stereospecific TRPV1 antagonists
Kim, Ho Shin, Jin, Mi-Kyoung, Kang, Sang-Uk, Lim, Ju-Ok, Tran, Phuong-Thao, Hoang, Van-Hai, Ann, Jihyae, Ha, Tae-Hwan, Pearce, Larry V., Pavlyukovets, Vladimir A., Blumberg, Peter M., Lee, Jeewoo
Published in Bioorganic & medicinal chemistry letters (15.06.2014)
Published in Bioorganic & medicinal chemistry letters (15.06.2014)
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Journal Article
N- N-substituted thiourea or urea derivatives and pharmaceutical composition for use in preventing or treating glutaminyl cyclase activity related diseases containing the same as an active ingredient
KIM YOUNG HO, HA HEE JIN, NGO THI HONG VAN, ANN JIHYAE, HOANG VAN HAI, KIM HEE, LEE JEEWOO, CHOI KWANG HYUN, YOO YOUNG DONG
Year of Publication 29.12.2020
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Year of Publication 29.12.2020
Patent
Asymmetric synthesis and receptor activity of chiral simplified resiniferatoxin (sRTX) analogues as transient receptor potential vanilloid 1 (TRPV1) ligands
Kim, Myeong Seop, Ki, Yooran, Ahn, Song Yeon, Yoon, Suyoung, Kim, Sung-Eun, Park, Hyeung-Geun, Sun, Wei, Son, Karam, Cui, Minghua, Choi, Sun, Pearce, Larry V., Esch, Timothy E., DeAndrea-Lazarus, Ian A., Blumberg, Peter M., Lee, Jeewoo
Published in Bioorganic & medicinal chemistry letters (01.01.2014)
Published in Bioorganic & medicinal chemistry letters (01.01.2014)
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Journal Article
Structure-Activity Relationship of Capsaicin Analogs and Transient Receptor Potential Vanilloid 1-Mediated Human Lung Epithelial Cell ToxicityS
Thomas, Karen C., Ethirajan, Manivannan, Shahrokh, Kiumars, Sun, Hao, Lee, Jeewoo, Cheatham, Thomas E., Yost, Garold S., Reilly, Christopher A.
Published in The Journal of pharmacology and experimental therapeutics (01.05.2011)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2011)
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