Adjustment of the lysosomal-mitochondrial axis for control of cellular senescence
Park, Joon Tae, Lee, Young-Sam, Cho, Kyung A, Park, Sang Chul
Published in Ageing research reviews (01.11.2018)
Published in Ageing research reviews (01.11.2018)
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Journal Article
ANT2 Accelerates Cutaneous Wound Healing in Aged Skin by Regulating Energy Homeostasis and Inflammation
Woo, Seung-Hwa, Mo, Yun Jeong, Lee, Yun-Il, Park, Ji Hwan, Hwang, Daehee, Park, Tae Jun, Kang, Hee Young, Park, Sang Chul, Lee, Young-Sam
Published in Journal of investigative dermatology (01.11.2023)
Published in Journal of investigative dermatology (01.11.2023)
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Journal Article
How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis
Lee, Young-Sam, Gao, Yang, Yang, Wei
Published in Nature structural & molecular biology (01.04.2015)
Published in Nature structural & molecular biology (01.04.2015)
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Journal Article
Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson‐Gilford progeria syndrome
Kang, Hyun Tae, Park, Joon Tae, Choi, Kobong, Choi, Hyo Jei Claudia, Jung, Chul Won, Kim, Gyu Ree, Lee, Young‐Sam, Park, Sang Chul
Published in Aging cell (01.06.2017)
Published in Aging cell (01.06.2017)
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Journal Article
Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase
Szymanski, Michal R, Kuznetsov, Vladmir B, Shumate, Christie, Meng, Qingchao, Lee, Young-Sam, Patel, Gayatri, Patel, Smita, Yin, Y Whitney
Published in The EMBO journal (14.07.2015)
Published in The EMBO journal (14.07.2015)
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Journal Article
Biliverdin regulates NR2E3 and zebrafish retinal photoreceptor development
Connor, Blaine, Titialii-Torres, Kayla, Rockenhaus, Abigail E, Passamonte, Samuel, Morris, Ann C, Lee, Young-Sam
Published in Scientific reports (04.05.2022)
Published in Scientific reports (04.05.2022)
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Journal Article
Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites
Lee, Joyce H., Mosher, Eric P., Lee, Young-Sam, Bumpus, Namandjé N., Berger, James M.
Published in Cell chemical biology (17.03.2022)
Published in Cell chemical biology (17.03.2022)
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Journal Article
Neuromyelitis optica (NMO)‐IgG‐driven organelle reorganization in human iPSC‐derived astrocytes
Cho, Sukhee, Lee, Hyein, Jung, Minkyo, Hong, Kirim, Woo, Seung‐Hwa, Lee, Young‐Sam, Kim, Byoung Joon, Jeon, Mi Young, Seo, Jinsoo, Mun, Ji Young
Published in The FASEB journal (01.10.2021)
Published in The FASEB journal (01.10.2021)
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Journal Article
The Mechanisms of Nuclear Proteotoxicity in Polyglutamine Spinocerebellar Ataxias
Lee, Davin, Lee, Yun-Il, Lee, Young-Sam, Lee, Sung Bae
Published in Frontiers in neuroscience (04.06.2020)
Published in Frontiers in neuroscience (04.06.2020)
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Journal Article
Mid-old cells are a potential target for anti-aging interventions in the elderly
Kim, Young Hwa, Lee, Young-Kyoung, Park, Soon Sang, Park, So Hyun, Eom, So Yeong, Lee, Young-Sam, Lee, Wonhee John, Jang, Juhee, Seo, Daeha, Kang, Hee Young, Kim, Jin Cheol, Lim, Su Bin, Yoon, Gyesoon, Kim, Hong Seok, Kim, Jang-Hee, Park, Tae Jun
Published in Nature communications (22.11.2023)
Published in Nature communications (22.11.2023)
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Journal Article
Global transcriptional downregulation of TREX and nuclear trafficking machinery as pan-senescence phenomena: evidence from human cells and tissues
Kim, Sung Young, Yang, Eun Jae, Lee, Sung Bae, Lee, Young-Sam, Cho, Kyoung A, Park, Sang Chul
Published in Experimental & molecular medicine (01.08.2020)
Published in Experimental & molecular medicine (01.08.2020)
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Journal Article
Nintedanib induces senolytic effect via STAT3 inhibition
Cho, Hyun-Ji, Hwang, Jeong-A, Yang, Eun Jae, Kim, Eok-Cheon, Kim, Jae-Ryong, Kim, Sung Young, Kim, Young Zoon, Park, Sang Chul, Lee, Young-Sam
Published in Cell death & disease (02.09.2022)
Published in Cell death & disease (02.09.2022)
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Journal Article
ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes
Lee, Hyein, Cho, Sukhee, Kim, Mi-Jin, Park, Yeo Jin, Cho, Eunji, Jo, Yeon Suk, Kim, Yong-Seok, Lee, Jung Yi, Thoudam, Themis, Woo, Seung-Hwa, Lee, Se-In, Jeon, Juyeong, Lee, Young-Sam, Suh, Byung-Chang, Yoon, Jong Hyuk, Go, Younghoon, Lee, In-Kyu, Seo, Jinsoo
Published in Cell reports (Cambridge) (31.10.2023)
Published in Cell reports (Cambridge) (31.10.2023)
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