Identification and expression analysis of miRNAs during batch culture of HEK-293 cells
Koh, Thong-Chuan, Lee, Yih-Yean, Chang, Siow-Qi, Nissom, Peter Morin
Published in Journal of biotechnology (25.03.2009)
Published in Journal of biotechnology (25.03.2009)
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Journal Article
Combined in silico modeling and metabolomics analysis to characterize fed-batch CHO cell culture
Selvarasu, Suresh, Ho, Ying Swan, Chong, William P. K., Wong, Niki S. C., Yusufi, Faraaz N. K., Lee, Yih Yean, Yap, Miranda G. S., Lee, Dong-Yup
Published in Biotechnology and bioengineering (01.06.2012)
Published in Biotechnology and bioengineering (01.06.2012)
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Journal Article
Digitally enabled approaches for the scale up of mammalian cell bioreactors
Karimi Alavijeh, Masih, Baker, Irene, Lee, Yih Yean, Gras, Sally L.
Published in Digital Chemical Engineering (01.09.2022)
Published in Digital Chemical Engineering (01.09.2022)
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Journal Article
Modeling Amino Acid Metabolism in Mammalian Cells-Toward the Development of a Model Library
Kontoravdi, Cleo, Wong, Danny, Lam, Carolyn, Lee, Yih Yean, Yap, Miranda G. S., Pistikopoulos, Efstratios N., Mantalaris, Athanasios
Published in Biotechnology progress (01.11.2007)
Published in Biotechnology progress (01.11.2007)
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Journal Article
Heat shock protein 27 overexpression in CHO cells modulates apoptosis pathways and delays activation of caspases to improve recombinant monoclonal antibody titre in fed-batch bioreactors
Tan, Janice G L, Lee, Yih Yean, Wang, Tianhua, Yap, Miranda G S, Tan, Tin Wee, Ng, Say Kong
Published in Biotechnology journal (01.05.2015)
Published in Biotechnology journal (01.05.2015)
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Journal Article
Coagulation factor IX analysis in bioreactor cell culture supernatant predicts quality of the purified product
Zacchi, Lucia F., Roche-Recinos, Dinora, Pegg, Cassandra L., Phung, Toan K., Napoli, Mark, Aitken, Campbell, Sandford, Vanessa, Mahler, Stephen M., Lee, Yih Yean, Schulz, Benjamin L., Howard, Christopher B.
Published in Communications biology (23.03.2021)
Published in Communications biology (23.03.2021)
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Journal Article
Transcriptome and proteome profiling to understanding the biology of high productivity CHO cells
Nissom, Peter Morin, Sanny, Arleen, Kok, Yee Jiun, Hiang, Yeo Thong, Chuah, Song Hui, Shing, Tan Kher, Lee, Yih Yean, Wong, Kathy Tin Kam, Hu, Wei-Shou, Sim, Miranda Yap Gek, Philp, Robin
Published in Molecular biotechnology (01.10.2006)
Published in Molecular biotechnology (01.10.2006)
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Journal Article
Overexpression of heat shock proteins (HSPs) in CHO cells for extended culture viability and improved recombinant protein production
Lee, Yih Yean, Wong, Kathy T.K., Tan, Janice, Toh, Poh Choo, Mao, Yanying, Brusic, Vesna, Yap, Miranda G.S.
Published in Journal of biotechnology (10.08.2009)
Published in Journal of biotechnology (10.08.2009)
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Journal Article
Adaptation of hybridomas to protein-free media results in a simplified two-step immunoglobulin M purification process
Lee, Jeremy, Tscheliessnig, Anne, Chen, Allen, Lee, Yih Yean, Adduci, Gloria, Choo, Andre, Jungbauer, Alois
Published in Journal of Chromatography A (27.03.2009)
Published in Journal of Chromatography A (27.03.2009)
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Journal Article
Conference Proceeding
Two-dimensional fluorescence difference gel electrophoresis for comparison of affinity and non-affinity based downstream processing of recombinant monoclonal antibody
Grzeskowiak, Julita K., Tscheliessnig, Anne, Toh, Poh Choo, Chusainow, Janet, Lee, Yih Yean, Wong, Niki, Jungbauer, Alois
Published in Journal of Chromatography A (12.06.2009)
Published in Journal of Chromatography A (12.06.2009)
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Journal Article
Identification of cellular genes critical to recombinant protein production using a Gaussia luciferase-based siRNA screening system
Lwa, Teng Rhui, Tan, Chuan Hao, Lew, Qiao Jing, Chu, Kai Ling, Tan, Janice, Lee, Yih Yean, Chao, Sheng-Hao
Published in Journal of biotechnology (15.04.2010)
Published in Journal of biotechnology (15.04.2010)
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Journal Article
Development and validation of a hybrid model for prediction of viable cell density, titer and cumulative glucose consumption in a mammalian cell culture system
Yatipanthalawa, Bhagya S., Wallace Fitzsimons, Shauna E., Horning, Tizita, Lee, Yih Yean, Gras, Sally L.
Published in Computers & chemical engineering (01.05.2024)
Published in Computers & chemical engineering (01.05.2024)
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Journal Article
Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications
MacDonald, Michael A., Nöbel, Matthias, Roche Recinos, Dinora, Martínez, Verónica S., Schulz, Benjamin L., Howard, Christopher B., Baker, Kym, Shave, Evan, Lee, Yih Yean, Marcellin, Esteban, Mahler, Stephen, Nielsen, Lars Keld, Munro, Trent
Published in Critical reviews in biotechnology (03.10.2022)
Published in Critical reviews in biotechnology (03.10.2022)
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Journal Article
S‑Trap Eliminates Cell Culture Media Polymeric Surfactants for Effective Proteomic Analysis of Mammalian Cell Bioreactor Supernatants
Zacchi, Lucia F, Recinos, Dinora Roche, Otte, Ellen, Aitken, Campbell, Hunt, Tony, Sandford, Vanessa, Lee, Yih Yean, Schulz, Benjamin L, Howard, Christopher B
Published in Journal of proteome research (01.05.2020)
Published in Journal of proteome research (01.05.2020)
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Journal Article