Efficacy and Safety of Abemaciclib, an Inhibitor of CDK4 and CDK6, for Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Other Solid Tumors
Patnaik, Amita, Rosen, Lee S, Tolaney, Sara M, Tolcher, Anthony W, Goldman, Jonathan W, Gandhi, Leena, Papadopoulos, Kyriakos P, Beeram, Muralidhar, Rasco, Drew W, Hilton, John F, Nasir, Aejaz, Beckmann, Richard P, Schade, Andrew E, Fulford, Angie D, Nguyen, Tuan S, Martinez, Ricardo, Kulanthaivel, Palaniappan, Li, Lily Q, Frenzel, Martin, Cronier, Damien M, Chan, Edward M, Flaherty, Keith T, Wen, Patrick Y, Shapiro, Geoffrey I
Published in Cancer discovery (01.07.2016)
Published in Cancer discovery (01.07.2016)
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Phase I dose-escalation trial of checkpoint kinase 1 inhibitor MK-8776 as monotherapy and in combination with gemcitabine in patients with advanced solid tumors
Daud, Adil I, Ashworth, Michelle T, Strosberg, Jonathan, Goldman, Jonathan W, Mendelson, David, Springett, Gregory, Venook, Alan P, Loechner, Sabine, Rosen, Lee S, Shanahan, Frances, Parry, David, Shumway, Stuart, Grabowsky, Jennifer A, Freshwater, Tomoko, Sorge, Christopher, Kang, Soonmo Peter, Isaacs, Randi, Munster, Pamela N
Published in Journal of clinical oncology (20.03.2015)
Published in Journal of clinical oncology (20.03.2015)
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Comparison of the pharmacokinetics and pharmacodynamics of S‐1 between Caucasian and East Asian patients
Chuah, Benjamin, Goh, Boon‐Cher, Lee, Soo‐Chin, Soong, Richie, Lau, Fayce, Mulay, Marilyn, Dinolfo, Melissa, Lim, Siew‐Eng, Soo, Ross, Furuie, Taro, Saito, Kaku, Zergebel, Christopher, Rosen, Lee S.
Published in Cancer science (01.02.2011)
Published in Cancer science (01.02.2011)
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Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis
Houk, Brett E, Bello, Carlo L, Poland, Bill, Rosen, Lee S, Demetri, George D, Motzer, Robert J
Published in Cancer chemotherapy and pharmacology (01.07.2010)
Published in Cancer chemotherapy and pharmacology (01.07.2010)
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Axitinib Is an Active Treatment for All Histologic Subtypes of Advanced Thyroid Cancer: Results From a Phase II Study
COHEN, Ezra E. W, ROSEN, Lee S, TORTORICI, Michael, SHALINSKY, David R, LIAU, Katherine F, COHEN, Roger B, VOKES, Everett E, KIES, Merrill S, FORASTIERE, Arlene A, WARDEN, Francis P, KANE, Madeleine A, SHERMAN, Eric, KIM, Sinil, BYCOTT, Paul
Published in Journal of clinical oncology (10.10.2008)
Published in Journal of clinical oncology (10.10.2008)
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First-In-Human Study of Cemiplimab Alone or In Combination with Radiotherapy and/or Low-dose Cyclophosphamide in Patients with Advanced Malignancies
Papadopoulos, Kyriakos P, Johnson, Melissa L, Lockhart, Albert C, Moore, Kathleen, Falchook, Gerald S, Formenti, Silvia C, Naing, Aung, Carvajal, Richard D, Rosen, Lee S, Weiss, Glen J, Leidner, Rom S, Li, Jingjin, Paccaly, Anne, Feng, Minjie, Stankevich, Elizabeth, Lowy, Israel, Fury, Matthew G, Crittenden, Marka R
Published in Clinical cancer research (01.03.2020)
Published in Clinical cancer research (01.03.2020)
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A first in human, safety, pharmacokinetics, and clinical activity phase I study of once weekly administration of the Hsp90 inhibitor ganetespib (STA-9090) in patients with solid malignancies
Goldman, Jonathan W, Raju, Robert N, Gordon, Gregory A, El-Hariry, Iman, Teofilivici, Florentina, Vukovic, Vojo M, Bradley, Robert, Karol, Michael D, Chen, Yu, Guo, Wei, Inoue, Takayo, Rosen, Lee S
Published in BMC cancer (25.03.2013)
Published in BMC cancer (25.03.2013)
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Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours
Infante, Jeffrey R, Korn, Ronald L, Rosen, Lee S, LoRusso, Patricia, Dychter, Samuel S, Zhu, Joy, Maneval, Daniel C, Jiang, Ping, Shepard, H Michael, Frost, Gregory, Von Hoff, Daniel D, Borad, Mitesh J, Ramanathan, Ramesh K
Published in British journal of cancer (2018)
Published in British journal of cancer (2018)
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A Phase I First-in-Human Study of TRC105 (Anti-Endoglin Antibody) in Patients with Advanced Cancer
ROSEN, Lee S, HURWITZ, Herbert I, THEUER, Charles P, LEIGH, Bryan R, GORDON, Michael S, WONG, Michael K, GOLDMAN, Jonathan, MENDELSON, David S, FIGG, William D, SPENCER, Shawn, ADAMS, Bonne J, ALVAREZ, Delia, SEON, Ben K
Published in Clinical cancer research (01.09.2012)
Published in Clinical cancer research (01.09.2012)
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Safety, Pharmacokinetics, and Antitumor Activity of AMG 386, a Selective Angiopoietin Inhibitor, in Adult Patients With Advanced Solid Tumors
HERBST, Roy S, HONG, David, EVELHOCH, Jeffrey L, OLINER, Jonathan D, LE, Ngocdiep, ROSEN, Lee S, LINNEA CHAP, KURZROCK, Razelle, JACKSON, Edward, SILVERMAN, Jeffrey M, RASMUSSEN, Erik, SUN, Yu-Nien, DON ZHONG, HWANG, Yuying C
Published in Journal of clinical oncology (20.07.2009)
Published in Journal of clinical oncology (20.07.2009)
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A First-in-Human Phase I Study of a Bivalent MET Antibody, Emibetuzumab (LY2875358), as Monotherapy and in Combination with Erlotinib in Advanced Cancer
Rosen, Lee S, Goldman, Jonathan W, Algazi, Alain P, Turner, P Kellie, Moser, Brian, Hu, Tianle, Wang, Xuejing Aimee, Tuttle, Jay, Wacheck, Volker, Wooldridge, James E, Banck, Michaela
Published in Clinical cancer research (15.04.2017)
Published in Clinical cancer research (15.04.2017)
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Tivantinib (ARQ 197), a Selective Inhibitor of MET, in Patients With Microphthalmia Transcription Factor―Associated Tumors: Results of a Multicenter Phase 2 Trial
WAGNER, Andrew J, GOLDBERG, John M, DAVIS, Ian J, FENG CHAI, WAGHORNE, Carol, SCHWARTZ, Brian, DEMETRI, George D, DUBOIS, Steven G, CHOY, Edwin, ROSEN, Lee, PAPPO, Alberto, GELLER, James, JUDSON, Ian, HOGG, David, SENZER, Neil
Published in Cancer (01.12.2012)
Published in Cancer (01.12.2012)
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Clinical outcomes of patients with advanced gastrointestinal stromal tumors: Safety and efficacy in a worldwide treatment‐use trial of sunitinib
Reichardt, Peter, Kang, Yoon‐Koo, Rutkowski, Piotr, Schuette, Jochen, Rosen, Lee S., Seddon, Beatrice, Yalcin, Suayib, Gelderblom, Hans, Williams, Charles C., Fumagalli, Elena, Biasco, Guido, Hurwitz, Herbert I., Kaiser, Pamela E., Fly, Kolette, Matczak, Ewa, Chen, Liang, Lechuga, Maria José, Demetri, George D.
Published in Cancer (01.05.2015)
Published in Cancer (01.05.2015)
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