Minocycline prevents glutamate‐induced apoptosis of cerebellar granule neurons by differential regulation of p38 and Akt pathways
Pi, Rongbiao, Li, Wenming, Lee, Nelson T. K., Chan, Hugh H. N., Pu, Yongmei, Chan, Ling Nga, Sucher, Nikolaus J., Chang, Donald C., Li, Mingtao, Han, Yifan
Published in Journal of neurochemistry (01.12.2004)
Published in Journal of neurochemistry (01.12.2004)
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Journal Article
Bis(7)‐tacrine attenuates β amyloid‐induced neuronal apoptosis by regulating L‐type calcium channels
Fu, Hongjun, Li, Wenming, Lao, Yuanzhi, Luo, Jialie, Lee, Nelson T. K., Kan, Kelvin K. W., Tsang, Hing Wai, Tsim, Karl W. K., Pang, Yuanping, Li, Zhiwang, Chang, Donald C., Li, Mingtao, Han, Yifan
Published in Journal of neurochemistry (01.09.2006)
Published in Journal of neurochemistry (01.09.2006)
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Journal Article
Synergistic Neuroprotection by Bis(7)-tacrine via Concurrent Blockade of N-Methyl-d-aspartate Receptors and Neuronal Nitric-Oxide Synthase
Li, Wenming, Xue, Jian, Niu, Chunying, Fu, Hongjun, Lam, Colin S C, Luo, Jialie, Chan, Hugh H N, Xue, Huaiguo, Kan, Kelvin K W, Lee, Nelson T K, Li, Chaoying, Pang, Yuanping, Li, Mingtao, Tsim, Karl W K, Jiang, Hualiang, Chen, Kaixian, Li, Xiaoyuan, Han, Yifan
Published in Molecular pharmacology (01.05.2007)
Published in Molecular pharmacology (01.05.2007)
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Journal Article
Mitochondrial Proteomic Analysis and Characterization of the Intracellular Mechanisms of Bis(7)-tacrine in Protecting against Glutamate-Induced Excitotoxicity in Primary Cultured Neurons
Fu, Hongjun, Li, Wenming, Liu, Yulin, Lao, Yuanzhi, Liu, Wei, Chen, Cheng, Yu, Hua, Lee, Nelson T. K, Chang, Donald C, Li, Peng, Pang, Yuanping, Tsim, Karl W. K, Li, Mingtao, Han, Yifan
Published in Journal of proteome research (01.07.2007)
Published in Journal of proteome research (01.07.2007)
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Journal Article
Bis(7)-tacrine, a promising anti-Alzheimer's dimer, affords dose- and time-dependent neuroprotection against transient focal cerebral ischemia
Zhao, Yuming, Li, Wenming, Chow, Peter C.Y., Lau, Dickson T.K., Lee, Nelson T.K., Pang, Yuanping, Zhang, Xuejun, Wang, Xiaoliang, Han, Yifan
Published in Neuroscience letters (11.07.2008)
Published in Neuroscience letters (11.07.2008)
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Journal Article
Promising anti-Alzheimer’s dimer bis(7)-tacrine reduces β-amyloid generation by directly inhibiting BACE-1 activity
Fu, Hongjun, Li, Wenming, Luo, Jialie, Lee, Nelson T.K., Li, Mingtao, Tsim, Karl W.K., Pang, Yuanping, Youdim, Moussa B.H., Han, Yifan
Published in Biochemical and biophysical research communications (15.02.2008)
Published in Biochemical and biophysical research communications (15.02.2008)
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Journal Article
Mecamylamine prevents neuronal apoptosis induced by glutamate and low potassium via differential anticholinergic-independent mechanisms
Fu, Hongjun, Dou, Juan, Li, Wenming, Luo, Jialie, Li, Kenny C., Lam, Colin S.C., Lee, Nelson T.K., Li, Mingtao, Han, Yifan
Published in Neuropharmacology (01.03.2008)
Published in Neuropharmacology (01.03.2008)
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Journal Article
Novel Dimeric Acetylcholinesterase Inhibitor Bis(7)-tacrine, but Not Donepezil, Prevents Glutamate-induced Neuronal Apoptosis by Blocking N-Methyl-d-aspartate Receptors
Li, Wenming, Pi, Rongbiao, Chan, Hugh H.N., Fu, Hongjun, Lee, Nelson T.K., Tsang, Hing Wai, Pu, Yongmei, Chang, Donald C., Li, Chaoying, Luo, Jialie, Xiong, Keming, Li, Zhiwang, Xue, Hong, Carlier, Paul R., Pang, Yuanping, Tsim, Karl W.K., Li, Mingtao, Han, Yifan
Published in The Journal of biological chemistry (06.05.2005)
Published in The Journal of biological chemistry (06.05.2005)
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Journal Article
Novel dimeric bis(7)-tacrine proton-dependently inhibits NMDA-activated currents
Luo, Jialie, Li, Wenming, Liu, Yuwei, Zhang, Wei, Fu, Hongjun, Lee, Nelson T.K., Yu, Hua, Pang, Yuanping, Huang, Pingbo, Xia, Jun, Li, Zhi-Wang, Li, Chaoying, Han, Yifan
Published in Biochemical and biophysical research communications (21.09.2007)
Published in Biochemical and biophysical research communications (21.09.2007)
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Journal Article
Neuroprotection via inhibition of nitric oxide synthase by bis(7)-tacrine
Li, Wenming, Lee, Nelson T K, Fu, Hongjun, Kan, Kelvin K W, Pang, Yuanping, Li, Mingtao, Tsim, Karl W K, Li, Xiaoyuan, Han, Yifan
Published in Neuroreport (03.04.2006)
Published in Neuroreport (03.04.2006)
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Journal Article
Bis(7)-tacrine attenuates [beta] amyloid-induced neuronal apoptosis by regulating L-type calcium channels
Fu, Hongjun, Li, Wenming, Lao, Yuanzhi, Luo, Jialie, Lee, Nelson T K, Kan, Kelvin K W, Tsang, Hing Wai, Tsim, Karl W K, Pang, Yuanping, Li, Zhiwang, Chang, Donald C, Li, Mingtao, Han, Yifan
Published in Journal of neurochemistry (01.09.2006)
Published in Journal of neurochemistry (01.09.2006)
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Journal Article
The expression of Cdk5, p35, p39, and Cdk5 kinase activity in developing, adult, and aged rat brains
WU, D.-C, YU, Y.-P, LEE, N. T. K, YU, A. C. H, WANG, J. H. C, HAN, Y.-F
Published in Neurochemical research (01.07.2000)
Published in Neurochemical research (01.07.2000)
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Conference Proceeding
Journal Article
Novel dimeric acetylcholinesterase inhibitor bis7-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors
Li, Wenming, Pi, Rongbiao, Chan, Hugh H N, Fu, Hongjun, Lee, Nelson T K, Tsang, Hing Wai, Pu, Yongmei, Chang, Donald C, Li, Chaoying, Luo, Jialie, Xiong, Keming, Li, Zhiwang, Xue, Hong, Carlier, Paul R, Pang, Yuanping, Tsim, Karl W K, Li, Mingtao, Han, Yifan
Published in The Journal of biological chemistry (06.05.2005)
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Published in The Journal of biological chemistry (06.05.2005)
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