G-749, a novel FLT3 kinase inhibitor, can overcome drug resistance for the treatment of acute myeloid leukemia
Lee, Hee Kyu, Kim, Hong Woo, Lee, In Yong, Lee, Jungmi, Lee, Jaekyoo, Jung, Dong Sik, Lee, Sang Yeop, Park, Sung Ho, Hwang, Haejun, Choi, Jang-Sik, Kim, Jung-Ho, Kim, Se Won, Kim, Jung Keun, Cools, Jan, Koh, Jong Sung, Song, Ho-Juhn
Published in Blood (03.04.2014)
Published in Blood (03.04.2014)
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Journal Article
Correction: Crystal Structure of Pim1 Kinase in Complex with a Pyrido[4,3-D]Pyrimidine Derivative Suggests a Unique Binding Mode
Lee, Sang Jae, Han, Byeong-Gu, Cho, Jea-Won, Choi, Jang-Sik, Lee, Jaekyoo, Song, Ho-Juhn, Koh, Jong Sung, Lee, Byung Il
Published in PloS one (02.01.2018)
Published in PloS one (02.01.2018)
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Superior Efficacy and Selectivity of Novel Small-Molecule Kinase Inhibitors of T790M-Mutant EGFR in Preclinical Models of Lung Cancer
Rho, Jin Kyung, Lee, In Yong, Choi, Yun Jung, Choi, Chang-Min, Hur, Jae-Young, Koh, Jong Sung, Lee, Jaekyoo, Suh, Byung-Chul, Song, Ho-Juhn, Salgaonkar, Paresh, Lee, Jungmi, Lee, Jaesang, Jung, Dong Sik, Kim, Sang-Yeob, Woo, Dong-Cheol, Baek, In-Jeoung, Lee, Joo-Yong, Ha, Chang Hoon, Sung, Young Hoon, Kim, Jeong Kon, Kim, Woo Sung, Song, Joon Seon, Kim, Cheol Hyeon, Bivona, Trever G, Lee, Jae Cheol
Published in Cancer research (Chicago, Ill.) (01.03.2017)
Published in Cancer research (Chicago, Ill.) (01.03.2017)
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Microwave-assisted one-pot synthesis of 2,3-disubstituted 3H-quinazolin-4-ones
Liu, JF, Lee, JY, Dalton, AM, Bi, G, Yu, LB, Baldino, CM, McElory, E, Brown, M
Published in Tetrahedron letters (21.02.2005)
Published in Tetrahedron letters (21.02.2005)
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Journal Article
Crystal structure of pim1 kinase in complex with a pyrido[4,3-d]pyrimidine derivative suggests a unique binding mode
Lee, Sang Jae, Han, Byeong-Gu, Cho, Jea-Won, Choi, Jang-Sik, Lee, Jaekyoo, Song, Ho-Juhn, Koh, Jong Sung, Lee, Byung Il
Published in PloS one (31.07.2013)
Published in PloS one (31.07.2013)
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Crystal Structures of Spleen Tyrosine Kinase in Complex with Two Novel 4-Aminopyrido[4,3-d] Pyrimidine Derivative Inhibitors
Lee, Sang Jae, Choi, Jang-Sik, Bong, Seoung Min, Hwang, Hae-Jun, Lee, Jaesang, Song, Ho-Juhn, Lee, Jaekyoo, Kim, Jung-Ho, Koh, Jong Sung, Lee, Byung Il
Published in Molecules and cells (2018)
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Published in Molecules and cells (2018)
Journal Article
Novel Small-Molecule ROCK2 Inhibitor GNS-3595 Attenuates Pulmonary Fibrosis in Preclinical Studies
Hwang, Soyoung, Lee, Wongil, Ravi, Dashnamoorthy, Devine, William, Yong, Miyong, Diebold, R Bruce, Seung, Sang-Ae, Ng, Nicholas W, Lee, Jaekyoo, Gupta, Anu, Koh, Jong Sung
Published in American journal of respiratory cell and molecular biology (01.10.2024)
Published in American journal of respiratory cell and molecular biology (01.10.2024)
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Epidemiological Relationship of Enterotoxigenic Escherichia coli and Enteroaggregative E. coli Isolated from Patients with Diarrhea in Seoul
Jin, Younghee, Seung, Hyunjung, Oh, Younghee, Jung, Jihun, Jeon, Sujin, Lee, Jaekyoo, Kim, ChangKyu, Choi, Sungmin, Chae, Youngzoo
Published in Journal of bacteriology and virology (2013)
Published in Journal of bacteriology and virology (2013)
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Journal Article
EGFR COMPOUNDS AND COMPOSITIONS FOR MODULATING EGFR MUTANT KINASE ACTIVITIES
LEE JAESANG, KOH JONG SUNG, SONG HO JUHN, SALGAONKAR PARESH DEVIDAS, SUH BYUNG CHUL, KIM JUNG HO, LEE IN YONG, KIM SE WON, JUNG DONG SIK, LEE JAEKYOO
Year of Publication 28.05.2024
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Year of Publication 28.05.2024
Patent
Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs
Lee, Sang Jae, Choi, Jang‐Sik, Han, Byeong‐Gu, Kim, Hyoun Sook, Song, Ho‐Juhn, Lee, Jaekyoo, Nam, Seungyoon, Goh, Sung‐Ho, Kim, Jung‐Ho, Koh, Jong Sung, Lee, Byung Il
Published in The FEBS journal (01.10.2016)
Published in The FEBS journal (01.10.2016)
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Journal Article
Highly potent and selective pyrazolylpyrimidines as Syk kinase inhibitors
Choi, Jang-Sik, Hwang, Hae-jun, Kim, Se-Won, Lee, Byung Il, Lee, Jaekyoo, Song, Ho-Juhn, Koh, Jong Sung, Kim, Jung-Ho, Lee, Phil Ho
Published in Bioorganic & medicinal chemistry letters (15.10.2015)
Published in Bioorganic & medicinal chemistry letters (15.10.2015)
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EGFR COMPOUNDS AND COMPOSITIONS FOR MODULATING EGFR MUTANT KINASE ACTIVITIES
LEE JAESANG, KOH JONG SUNG, SONG HO JUHN, SALGAONKAR PARESH DEVIDAS, SUH BYUNG CHUL, KIM JUNG HO, LEE IN YONG, KIM SE WON, JUNG DONG SIK, LEE JAEKYOO
Year of Publication 19.01.2023
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Year of Publication 19.01.2023
Patent
P3.02b-119 YH25448, a Highly Selective 3rd Generation EGFR TKI, Exhibits Superior Survival over Osimertinib in Animal Model with Brain Metastases from NSCLC
Hong, Min Hee, Lee, In Yong, Koh, Jong Sung, Lee, Jaekyoo, Suh, Byung-Chul, Song, Ho-Juhn, Salgaonkar, Paresh, Lee, Jaesang, Lee, Young-Sung, Oh, Se-Woong, Kim, Jong Kyun, Nam, Su Youn, Cho, Byoung Chul
Published in Journal of thoracic oncology (01.01.2017)
Published in Journal of thoracic oncology (01.01.2017)
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Journal Article
P3.02b-119 YH25448, a Highly Selective 3rd Generation EGFR TKI, Exhibits Superior Survival over Osimertinib in Animal Model with Brain Metastases from NSCLC: Topic: EGFR RES
Hong, Min Hee, Lee, In Yong, Koh, Jong Sung, Lee, Jaekyoo, Suh, Byung-Chul, Song, Ho-Juhn, Salgaonkar, Paresh, Lee, Jaesang, Lee, Young-Sung, Oh, Se-Woong, Kim, Jong Kyun, Nam, Su Youn, Cho, Byoung Chul
Published in Journal of thoracic oncology (01.01.2017)
Published in Journal of thoracic oncology (01.01.2017)
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Journal Article
Crystal Structures of Spleen Tyrosine Kinase in Complex with Two Novel 4-Aminopyrido[4,3-d] Pyrimidine Derivative Inhibitors
Lee, Sang Jae, Choi, Jang-Sik, Bong, Seoung Min, Hwang, Hae-Jun, Lee, Jaesang, Song, Ho-Juhn, Lee, Jaekyoo, Kim, Jung-Ho, Koh, Jong Sung, Lee, Byung Il
Published in Molecules and cells (01.06.2018)
Published in Molecules and cells (01.06.2018)
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Journal Article
LRRK2 억제제로서의 피롤로피리미딘 유도체
CHOI JANG SIK, PARK SONG EUN, KOH JONG SUNG, KIM HWA SIL, KIM JUNG HO, KIM SE WON, JUNG DONG SIK, LEE JAEKYOO
Year of Publication 15.07.2020
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Year of Publication 15.07.2020
Patent
CRYSTAL POLYMORPH OF 8-BROMO-2-(1-METHYLPIPERIDIN-4-YLAMINO)-4-(4-PHENOXYPHENYLAMINO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE HYDROCHLORIDE AND METHOD FOR PREPARING SAME
PARK, Song-eun, KIM, Se-Won, LEE, Hee Kyu, JUNG, Dong-Sik, KIM, Jung-Ho, CHOI, Jang-Sik, KOH, Jong-Sung, CHOI, Yung-Geun, LEE, Jaekyoo
Year of Publication 27.02.2020
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Year of Publication 27.02.2020
Patent
EGFR COMPOUNDS AND COMPOSITIONS FOR MODULATING EGFR MUTANT KINASE ACTIVITIES
LEE JAESANG, KOH JONG SUNG, SONG HO JUHN, SALGAONKAR PARESH DEVIDAS, SUH BYUNG CHUL, KIM JUNG HO, LEE IN YONG, KIM SE WON, JUNG DONG SIK, LEE JAEKYOO
Year of Publication 29.01.2021
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Year of Publication 29.01.2021
Patent
COMPOUNDS AND COMPOSITIONS FOR MODULATING EGFR MUTANT KINASE ACTIVITIES
SUH BYUNGUL, PARESH DEVIDAS SALGAONKAR, KIM SE-WON, LEE JAESANG, SONG HO-JUHN, KOH JONG SUNG, KIM JUNG-HO, LEE IN YONG, JUNG DONG SIK, LEE JAEKYOO
Year of Publication 10.12.2020
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Year of Publication 10.12.2020
Patent
Abstract C196: A novel selective inhibitor of FLT3 kinase as a therapeutics for AML
Lee, Hee Kyu, Kim, Hong Woo, Song, Ho-Juhn, Lee, Jaekyoo, Lee, In Yong, Kim, Youngsam, Koh, Jong Sung
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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