Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2′,3′ cGAMP Signaling
Kranzusch, Philip J., Wilson, Stephen C., Lee, Amy S.Y., Berger, James M., Doudna, Jennifer A., Vance, Russell E.
Published in Molecular cell (17.09.2015)
Published in Molecular cell (17.09.2015)
Get full text
Journal Article
Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity
Kranzusch, Philip J., Lee, Amy S.Y., Wilson, Stephen C., Solovykh, Mikhail S., Vance, Russell E., Berger, James M., Doudna, Jennifer A.
Published in Cell (28.08.2014)
Published in Cell (28.08.2014)
Get full text
Journal Article
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
Nuñez, James K., Lee, Amy S. Y., Engelman, Alan, Doudna, Jennifer A.
Published in Nature (London) (12.03.2015)
Published in Nature (London) (12.03.2015)
Get full text
Journal Article
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
Lee, Amy S. Y., Kranzusch, Philip J., Doudna, Jennifer A., Cate, Jamie H. D.
Published in Nature (London) (04.08.2016)
Published in Nature (London) (04.08.2016)
Get full text
Journal Article
LIN28B alters ribosomal dynamics to promote metastasis in MYCN-driven malignancy
Missios, Pavlos, da Rocha, Edroaldo Lummertz, Pearson, Daniel S, Philipp, Julia, Aleman, Maria M, Pirouz, Mehdi, Farache, Dorian, Franses, Joseph W, Kubaczka, Caroline, Tsanov, Kaloyan M, Jha, Deepak K, Pepe-Mooney, Brian, Powers, John T, Gregory, Richard I, Lee, Amy Sy, Dominguez, Daniel, Ting, David T, Daley, George Q
Published in The Journal of clinical investigation (15.11.2021)
Published in The Journal of clinical investigation (15.11.2021)
Get full text
Journal Article
Bacterial cGAS-like enzymes synthesize diverse nucleotide signals
Whiteley, Aaron T., Eaglesham, James B., de Oliveira Mann, Carina C., Morehouse, Benjamin R., Lowey, Brianna, Nieminen, Eric A., Danilchanka, Olga, King, David S., Lee, Amy S. Y., Mekalanos, John J., Kranzusch, Philip J.
Published in Nature (London) (01.03.2019)
Published in Nature (London) (01.03.2019)
Get full text
Journal Article
cGAS-like receptors sense RNA and control 3′2′-cGAMP signalling in Drosophila
Slavik, Kailey M., Morehouse, Benjamin R., Ragucci, Adelyn E., Zhou, Wen, Ai, Xianlong, Chen, Yuqiang, Li, Lihua, Wei, Ziming, Bähre, Heike, König, Martin, Seifert, Roland, Lee, Amy S. Y., Cai, Hua, Imler, Jean-Luc, Kranzusch, Philip J.
Published in Nature (London) (02.09.2021)
Published in Nature (London) (02.09.2021)
Get full text
Journal Article
CBASS Immunity Uses CARF-Related Effectors to Sense 3′–5′- and 2′–5′-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection
Lowey, Brianna, Whiteley, Aaron T., Keszei, Alexander F.A., Morehouse, Benjamin R., Mathews, Ian T., Antine, Sadie P., Cabrera, Victor J., Kashin, Dmitry, Niemann, Percy, Jain, Mohit, Schwede, Frank, Mekalanos, John J., Shao, Sichen, Lee, Amy S.Y., Kranzusch, Philip J.
Published in Cell (09.07.2020)
Published in Cell (09.07.2020)
Get full text
Journal Article
Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity
Dixit, Evelyn, Boulant, Steeve, Zhang, Yijing, Lee, Amy S.Y., Odendall, Charlotte, Shum, Bennett, Hacohen, Nir, Chen, Zhijian J., Whelan, Sean P., Fransen, Marc, Nibert, Max L., Superti-Furga, Giulio, Kagan, Jonathan C.
Published in Cell (14.05.2010)
Published in Cell (14.05.2010)
Get full text
Journal Article
A large-scale type I CBASS antiphage screen identifies the phage prohead protease as a key determinant of immune activation and evasion
Richmond-Buccola, Desmond, Hobbs, Samuel J., Garcia, Jasmine M., Toyoda, Hunter, Gao, Jingjing, Shao, Sichen, Lee, Amy S.Y., Kranzusch, Philip J.
Published in Cell host & microbe (10.07.2024)
Published in Cell host & microbe (10.07.2024)
Get full text
Journal Article
A complex suite of loci and elements in eukaryotic type II topoisomerases determine selective sensitivity to distinct poisoning agents
Blower, Tim R, Bandak, Afif, Lee, Amy S Y, Austin, Caroline A, Nitiss, John L, Berger, James M
Published in Nucleic acids research (05.09.2019)
Published in Nucleic acids research (05.09.2019)
Get full text
Journal Article
A molecular filter for the cnidarian stinging response
Weir, Keiko, Dupre, Christophe, van Giesen, Lena, Lee, Amy S-Y, Bellono, Nicholas W
Published in eLife (26.05.2020)
Published in eLife (26.05.2020)
Get full text
Journal Article
eIF3d is an mRNA cap-binding protein required for specialized translation initiation
Lee, Amy S.Y., Kranzusch, Philip J., Doudna, Jennifer A., Cate, Jamie H.D.
Published in Nature (London) (04.08.2016)
Published in Nature (London) (04.08.2016)
Get full text
Journal Article