Immunogenicity and Tolerability of a SARS-CoV-2 TNX-1800, a Live Recombinant Poxvirus Vaccine Candidate, in Syrian Hamsters and New Zealand White Rabbits
Awasthi, Mayanka, Macaluso, Anthony, Goebel, Scott J, Luea, Erin, Noyce, Ryan S, Nasar, Farooq, Daugherty, Bruce, Bavari, Sina, Lederman, Seth
Published in Viruses (01.10.2023)
Published in Viruses (01.10.2023)
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Journal Article
1346 mTFF2-MSA (mTNX-1700) suppresses tumor growth in an Anti-PD-1 treated Pan02 syngeneic pancreatic cancer model by targeting MDSCs in C57BL/6 Mice
Daugherty, Bruce L, Zhao, Grace, Zang, Mingfa, Qian, Jin, Wang, Timothy C, Lederman, Seth
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
481 A CXCR4 partial agonist TFF2-MSA sensitized advanced gastric cancer to PD-1 blockade by systematically reducing PMN-MDSC accumulation, immunosuppression, and generation in bone marrow
Qian, Jin, Ryeom, Sandra, Daugherty, Bruce L, Lederman, Seth, Wang, Timothy C
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
Single Dose of Recombinant Chimeric Horsepox Virus (TNX-801) Vaccination Protects Macaques from Lethal Monkeypox Challenge
Noyce, Ryan S, Westfall, Landon W, Fogarty, Siobhan, Gilbert, Karen, Mpanju, Onesmo, Stillwell, Helen, Esparza, José, Daugherty, Bruce, Koide, Fusataka, Evans, David H, Lederman, Seth
Published in Viruses (26.01.2023)
Published in Viruses (26.01.2023)
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High-Throughput Screening Assay for Convalescent Sera in COVID-19: Efficacy, Donor Selection, and Variant Neutralization
Kota, Krishna P, Trakht, Ilya, Kalantarov, Gavreel, Ordonez, David, Wei, Jiayi, Trefry, Stephanie, Bavari, Evia, Richardson, Jenny, Zamani, Rouzbeh, Raney, Christy, Nasar, Farooq, Daugherty, Bruce, Lederman, Seth, Bavari, Sina
Published in Microorganisms (Basel) (23.07.2024)
Published in Microorganisms (Basel) (23.07.2024)
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Journal Article
Immunogenicity and Efficacy of TNX-1800, A Live Virus Recombinant Poxvirus Vaccine Candidate, against SARS-CoV-2 Challenge in Nonhuman Primates
Awasthi, Mayanka, Macaluso, Anthony, Myscofski, Dawn, Prigge, Jon, Koide, Fusataka, Noyce, Ryan S, Fogarty, Siobhan, Stillwell, Helen, Goebel, Scott J, Daugherty, Bruce, Nasar, Farooq, Bavari, Sina, Lederman, Seth
Published in Vaccines (Basel) (01.11.2023)
Published in Vaccines (Basel) (01.11.2023)
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Journal Article
1345 mTFF2-MSA (mTNX-1700) suppresses tumor growth and increases survival in anti-PD-1 treated CT26.wt subcutaneous and CT26-Luciferase orthotopic syngeneic colorectal cancer models by targeting MDSCs
Daugherty, Bruce L, Boohaker, Rebecca J, Johnstone, Rebecca, Stinson, Karr, Zhao, Grace, Zang, Mingfa, Qian, Jin, Wang, Timothy C, Lederman, Seth
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
Ligation of CD40 on fibroblasts induces CD54 (ICAM-1) and CD106 (VCAM-1) up-regulation and IL-6 production and proliferation
Yellin, Michael J., Winikoff, Stephen, Fortune, Sarah M., Baum, David, Crow, Mary K., Lederman, Seth, Chess, Leonard
Published in Journal of leukocyte biology (01.08.1995)
Published in Journal of leukocyte biology (01.08.1995)
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Effect of MDSC-targeted TFF2-MSA with PD-1 blockade therapy in advanced gastric cancer models
Qian, Jin, Ryeom, Sandra, Daugherty, Bruce L, Lederman, Seth M., Wang, Timothy C.
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
Efficacy and Safety of Sublingual Cyclobenzaprine for the Treatment of Fibromyalgia: Results From a Randomized, Double-Blind, Placebo-Controlled Trial
Lederman, Seth, Arnold, Lesley M, Vaughn, Ben, Kelley, Mary, Sullivan, Gregory M
Published in Arthritis care & research (2010) (01.11.2023)
Published in Arthritis care & research (2010) (01.11.2023)
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Early smallpox vaccine manufacturing in the United States: Introduction of the “animal vaccine” in 1870, establishment of “vaccine farms”, and the beginnings of the vaccine industry
Esparza, José, Lederman, Seth, Nitsche, Andreas, Damaso, Clarissa R.
Published in Vaccine (19.06.2020)
Published in Vaccine (19.06.2020)
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Journal Article
Effect of TFF2-MSA on tumor growth and survival in anti-PD-1 treated MC38 and CT26.wt colorectal cancer models by targeting MDSCs
Daugherty, Bruce L, Boohaker, Rebecca J, Johnstone, Rebecca, Stinson, Karr, Qian, Jin, Wang, Timothy C., Lederman, Seth M.
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
Abstract 6640: Stabilized recombinant trefoil factor 2 (TFF2-CTP) enhances anti-tumor activity of PD-1 blockade in mouse models of colorectal cancer
Kim, Woosook, Fu, Na, Duddempudi, Phaneendra, Dubeykovskaya, Zinaida, Almo, Steven, Guha, Chandan, Lederman, Seth, Wang, Timothy
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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A phase 3, randomized, placebo-controlled, trial to evaluate the efficacy and safety of bedtime sublingual cyclobenzaprine (TNX-102 SL) in military-related posttraumatic stress disorder
Parmenter, Megan E., Lederman, Seth, Weathers, Frank W., Davis, Lori L., Vaughn, Benjamin, Engels, Jean, Sullivan, Gregory M.
Published in Psychiatry research (01.04.2024)
Published in Psychiatry research (01.04.2024)
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Journal Article
TNX-1500, an Fc-modified Anti-CD154 Antibody, Prolongs Nonhuman Primate Cardiac Allograft Survival
Miura, Shuhei, Habibabady, Zahra A., Pollok, Franziska, Ma, Madelyn, Rosales, Ivy A, Kinoshita, Kohei, Pratts, Shannon, McGrath, Gannon, Chaban, Ryan, Fogarty, Siobhan, Meibohm, Bernd, Daugherty, Bruce, Lederman, Seth, Pierson, Richard N.
Published in American journal of transplantation (07.04.2023)
Published in American journal of transplantation (07.04.2023)
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Journal Article
TNX-1500, a crystallizable fragment–modified anti-CD154 antibody, prolongs nonhuman primate renal allograft survival
Lassiter, Grace, Otsuka, Ryo, Hirose, Takayuki, Rosales, Ivy, Karadagi, Ahmad, Tomosugi, Toshihide, Dehnadi, Abbas, Lee, Hang, Colvin, Robert B., Baardsnes, Jason, Moraitis, Anna, Smith, Emma E., Ali, Zahida, Berhe, Phil, Mulder, Andrew, Meibohm, Bernd, Daugherty, Bruce, Fogarty, Siobhan, Pierson, Richard N., Lederman, Seth, Kawai, Tatsuo
Published in American journal of transplantation (01.08.2023)
Published in American journal of transplantation (01.08.2023)
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