The multi-tasked life of GM1 ganglioside, a true factotum of nature
Ledeen, Robert W., Wu, Gusheng
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.07.2015)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.07.2015)
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Journal Article
Galectins: their network and roles in immunity/tumor growth control
Kaltner, Herbert, Toegel, Stefan, Caballero, Gabriel García, Manning, Joachim C., Ledeen, Robert W., Gabius, Hans-Joachim
Published in Histochemistry and Cell Biology (01.02.2017)
Published in Histochemistry and Cell Biology (01.02.2017)
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Journal Article
Book Review
Mice deficient in GM1 manifest both motor and non-motor symptoms of Parkinson's disease; successful treatment with synthetic GM1 ganglioside
Wu, Gusheng, Lu, Zi-Hua, Seo, Joon Ho, Alselehdar, Samar K., DeFrees, Shawn, Ledeen, Robert W.
Published in Experimental neurology (01.07.2020)
Published in Experimental neurology (01.07.2020)
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Journal Article
Deficiency of ganglioside GM1 correlates with Parkinson's disease in mice and humans
Wu, Gusheng, Lu, Zi-Hua, Kulkarni, Neil, Ledeen, Robert W.
Published in Journal of neuroscience research (01.10.2012)
Published in Journal of neuroscience research (01.10.2012)
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Journal Article
Gangliosides, α-Synuclein, and Parkinson's Disease
Ledeen, Robert W, Wu, Gusheng
Published in Progress in molecular biology and translational science (2018)
Published in Progress in molecular biology and translational science (2018)
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Journal Article
Functional interplay between ganglioside GM1 and cross‐linking galectin‐1 induces axon‐like neuritogenesis via integrin‐based signaling and TRPC5‐dependent Ca2+ influx
Wu, Gusheng, Lu, Zi‐Hua, André, Sabine, Gabius, Hans‐Joachim, Ledeen, Robert W.
Published in Journal of neurochemistry (01.02.2016)
Published in Journal of neurochemistry (01.02.2016)
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Journal Article
Cross-Linking of GM1 Ganglioside by Galectin-1 Mediates Regulatory T Cell Activity Involving TRPC5 Channel Activation: Possible Role in Suppressing Experimental Autoimmune Encephalomyelitis
Wang, Jianfeng, Lu, Zi-Hua, Gabius, Hans-Joachim, Rohowsky-Kochan, Christine, Ledeen, Robert W, Wu, Gusheng
Published in The Journal of immunology (1950) (01.04.2009)
Published in The Journal of immunology (1950) (01.04.2009)
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Journal Article
GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model
Hadaczek, Piotr, Wu, Gusheng, Sharma, Nitasha, Ciesielska, Agnieszka, Bankiewicz, Krystof, Davidow, Amy L., Lu, Zi-Hua, Forsayeth, John, Ledeen, Robert W.
Published in Experimental neurology (01.01.2015)
Published in Experimental neurology (01.01.2015)
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Journal Article
Mice Lacking Major Brain Gangliosides Develop Parkinsonism
Wu, Gusheng, Lu, Zi-Hua, Kulkarni, Neil, Amin, Ruchi, Ledeen, Robert W.
Published in Neurochemical research (01.09.2011)
Published in Neurochemical research (01.09.2011)
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Journal Article
Parkinson’s disease recovery by GM1 oligosaccharide treatment in the B4galnt1+/− mouse model
Chiricozzi, Elena, Mauri, Laura, Lunghi, Giulia, Di Biase, Erika, Fazzari, Maria, Maggioni, Margherita, Valsecchi, Manuela, Prioni, Simona, Loberto, Nicoletta, Pomè, Diego Yuri, Ciampa, Maria Grazia, Fato, Pamela, Verlengia, Gianluca, Cattaneo, Stefano, Assini, Robert, Wu, Gusheng, Alselehdar, Samar, Ledeen, Robert W., Sonnino, Sandro
Published in Scientific reports (18.12.2019)
Published in Scientific reports (18.12.2019)
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Journal Article
Beyond glycoproteins as galectin counterreceptors: effector T cell growth control of tumors via ganglioside GM1
Ledeen, Robert W, Wu, Gusheng, Andre, Sabine, Bleich, David, Huet, Guillemette, Kaltner, Herbert, Kopitz, Juergen, Gabius, Hans-Joachim
Published in Annals of the New York Academy of Sciences (01.04.2012)
Published in Annals of the New York Academy of Sciences (01.04.2012)
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Journal Article
Ganglioside accumulation in activated glia in the developing brain: comparison between WT and GalNAcT KO mice
Saito, Mariko, Wu, Gusheng, Hui, Maria, Masiello, Kurt, Dobrenis, Kostantin, Ledeen, Robert W., Saito, Mitsuo
Published in Journal of lipid research (01.08.2015)
Published in Journal of lipid research (01.08.2015)
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Journal Article