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Leonard, John P, Natoli, Thomas A, Rogers, Kelly A, Russo, Ryan J, Ibraghimov-Beskrovnaya, Oxana, Husson, Hervé, Budman, Yeva, Wang, Bing, Bukanov, Nikolay O, Smith, Laurie A, Belenky, Alexei, Komarnitsky, Svetlana, Shayman, James A, Ledbetter, Steven R, Dackowski, William R
Published in Nature medicine (01.07.2010)
Published in Nature medicine (01.07.2010)
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CaMKII as a pathological mediator of ER stress, oxidative stress, and mitochondrial dysfunction in a murine model of nephronophthisis
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Published in American journal of physiology. Renal physiology (01.06.2016)
Published in American journal of physiology. Renal physiology (01.06.2016)
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Blocking TGF-β Signaling Pathway Preserves Mitochondrial Proteostasis and Reduces Early Activation of PDGFRβ+ Pericytes in Aristolochic Acid Induced Acute Kidney Injury in Wistar Male Rats
Pozdzik, Agnieszka A, Giordano, Laetitia, Li, Gang, Antoine, Marie-Hélène, Quellard, Nathalie, Godet, Julie, De Prez, Eric, Husson, Cécile, Declèves, Anne-Emilie, Arlt, Volker M, Goujon, Jean-Michel, Brochériou-Spelle, Isabelle, Ledbetter, Steven R, Caron, Nathalie, Nortier, Joëlle L
Published in PloS one (05.07.2016)
Published in PloS one (05.07.2016)
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CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD
Bukanov, Nikolay O., Moreno, Sarah E., Natoli, Thomas A., Rogers, Kelly A., Smith, Laurie A., Ledbetter, Steven R., Oumata, Nassima, Galons, Hervé, Meijer, Laurent, Ibraghimov-Beskrovnaya, Oxana
Published in Cell cycle (Georgetown, Tex.) (01.11.2012)
Published in Cell cycle (Georgetown, Tex.) (01.11.2012)
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A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis
Trachtman, Howard, Fervenza, Fernando C., Gipson, Debbie S., Heering, Peter, Jayne, David R.W., Peters, Harm, Rota, Stefano, Remuzzi, Giuseppe, Rump, L. Christian, Sellin, Lorenz K., Heaton, Jeremy P.W., Streisand, James B., Hard, Marjie L., Ledbetter, Steven R., Vincenti, Flavio
Published in Kidney international (01.06.2011)
Published in Kidney international (01.06.2011)
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CXA-10, a Nitrated Fatty Acid, Is Renoprotective in Deoxycorticosterone Acetate-Salt Nephropathy
Arbeeny, Cynthia M, Ling, Hong, Smith, Mandy M, O'Brien, Stephen, Wawersik, Stefan, Ledbetter, Steven R, McAlexander, Allen, Schopfer, Francisco J, Willette, Robert N, Jorkasky, Diane K
Published in The Journal of pharmacology and experimental therapeutics (01.06.2019)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2019)
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Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis
Husson, Hervé, Moreno, Sarah, Smith, Laurie A, Smith, Mandy M, Russo, Ryan J, Pitstick, Rose, Sergeev, Mikhail, Ledbetter, Steven R, Bukanov, Nikolay O, Lane, Monica, Zhang, Kate, Billot, Katy, Carlson, George, Shah, Jagesh, Meijer, Laurent, Beier, David R, Ibraghimov-Beskrovnaya, Oxana
Published in Human molecular genetics (01.06.2016)
Published in Human molecular genetics (01.06.2016)
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Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine
Ledbetter, Steven R, Ibraghimov-Beskrovnaya, Oxana, Smith, Laurie A, Klinger, Katherine W, Bukanov, Nikolay O
Published in Nature (14.12.2006)
Published in Nature (14.12.2006)
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Role of TGF‐β in a Mouse Model of High Turnover Renal Osteodystrophy
Liu, Shiguang, Song, Wenping, Boulanger, Joseph H, Tang, Wen, Sabbagh, Yves, Kelley, Brian, Gotschall, Russell, Ryan, Susan, Phillips, Lucy, Malley, Katie, Cao, Xiaohong, Xia, Tai‐He, Zhen, Gehua, Cao, Xu, Ling, Hong, Dechow, Paul C, Bellido, Teresita M, Ledbetter, Steven R, Schiavi, Susan C
Published in Journal of bone and mineral research (01.05.2014)
Published in Journal of bone and mineral research (01.05.2014)
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Protective effect of 20-HETE analogues in experimental renal ischemia reperfusion injury
Regner, Kevin R., Zuk, Anna, Van Why, Scott K., Shames, Brian D., Ryan, Robert P., Falck, John R., Manthati, Vijay L., McMullen, Meghan E., Ledbetter, Steven R., Roman, Richard J.
Published in Kidney international (01.03.2009)
Published in Kidney international (01.03.2009)
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Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease
NATOLI, Thomas A, HUSSON, Hervé, IBRAGHIMOV-BESKROVNAYA, Oxana, ROGERS, Kelly A, SMITH, Laurie A, BING WANG, BUDMAN, Yeva, BUKANOV, Nikolay O, LEDBETTER, Steven R, KLINGER, Katherine W, LEONARD, John P
Published in Human molecular genetics (01.08.2012)
Published in Human molecular genetics (01.08.2012)
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Renoprotective effects of anti-TGF-β antibody and antihypertensive therapies in Dahl S rats
Murphy, Sydney R, Dahly-Vernon, Annette J, Dunn, Kathryn M J, Chen, Chun Cheng Andy, Ledbetter, Steven R, Williams, Jan M, Roman, Richard J
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.07.2012)
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.07.2012)
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Effect of combination therapy with enalapril and the TGF-beta antagonist 1D11 in unilateral ureteral obstruction
El Chaar, Maher, Chen, Jie, Seshan, Surya V, Jha, Sharda, Richardson, Ingride, Ledbetter, Steven R, Vaughan, Jr, E D, Poppas, Dix P, Felsen, Diane
Published in American journal of physiology. Renal physiology (01.04.2007)
Published in American journal of physiology. Renal physiology (01.04.2007)
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Differences in the timing and magnitude of Pkd1 gene deletion determine the severity of polycystic kidney disease in an orthologous mouse model of ADPKD
Rogers, Kelly A., Moreno, Sarah E., Smith, Laurie A., Husson, Hervé, Bukanov, Nikolay O., Ledbetter, Steven R., Budman, Yeva, Lu, Yuefeng, Wang, Bing, Ibraghimov‐Beskrovnaya, Oxana, Natoli, Thomas A.
Published in Physiological reports (01.06.2016)
Published in Physiological reports (01.06.2016)
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Transforming Growth Factor-β, 20-HETE Interaction, and Glomerular Injury in Dahl Salt-Sensitive Rats
Dahly-Vernon, Annette J, Sharma, Mukut, McCarthy, Ellen T, Savin, Virginia J, Ledbetter, Steven R, Roman, Richard J
Published in Hypertension (Dallas, Tex. 1979) (01.04.2005)
Published in Hypertension (Dallas, Tex. 1979) (01.04.2005)
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Antihypertensive effects of chronic anti-TGF-beta antibody therapy in Dahl S rats
Dahly, Annette J, Hoagland, Kimberly M, Flasch, Averia K, Jha, Sharda, Ledbetter, Steven R, Roman, Richard J
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.09.2002)
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.09.2002)
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LIN JULIE, LEDBETTER STEVEN R, FINN PATRICK, POMPONIO ROBERT JOHN, ENGSTRAND SARA
Year of Publication 23.02.2018
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Year of Publication 23.02.2018
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ANTIBODIES TO TGFβ
HOLGATE ROBERT G, JERMUTUS LUTZ U, LEDBETTER STEVEN R, DUNCAN ALEXANDER R, BUCHANAN CATRIONA L, FINCH DONNA K, HART CELIA P
Year of Publication 14.12.2017
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Year of Publication 14.12.2017
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CXC Chemokines Connective Tissue Activating Peptide-III and Neutrophil Activating Peptide-2 are Heparin/Heparan Sulfate-degrading Enzymes (∗)
Hoogewerf, Arlene J., Leone, Joseph W., Reardon, Ilene M., Howe, W.Jeffrey, Asa, Darwin, Heinrikson, Robert L., Ledbetter, Steven R.
Published in The Journal of biological chemistry (17.02.1995)
Published in The Journal of biological chemistry (17.02.1995)
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