Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia
Orlando, Elena J., Han, Xia, Tribouley, Catherine, Wood, Patricia A., Leary, Rebecca J., Riester, Markus, Levine, John E., Qayed, Muna, Grupp, Stephan A., Boyer, Michael, De Moerloose, Barbara, Nemecek, Eneida R., Bittencourt, Henrique, Hiramatsu, Hidefumi, Buechner, Jochen, Davies, Stella M., Verneris, Michael R., Nguyen, Kevin, Brogdon, Jennifer L., Bitter, Hans, Morrissey, Michael, Pierog, Piotr, Pantano, Serafino, Engelman, Jeffrey A., Winckler, Wendy
Published in Nature medicine (01.10.2018)
Published in Nature medicine (01.10.2018)
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Studying clonal dynamics in response to cancer therapy using high-complexity barcoding
Bhang, Hyo-eun C, Ruddy, David A, Krishnamurthy Radhakrishna, Viveksagar, Caushi, Justina X, Zhao, Rui, Hims, Matthew M, Singh, Angad P, Kao, Iris, Rakiec, Daniel, Shaw, Pamela, Balak, Marissa, Raza, Alina, Ackley, Elizabeth, Keen, Nicholas, Schlabach, Michael R, Palmer, Michael, Leary, Rebecca J, Chiang, Derek Y, Sellers, William R, Michor, Franziska, Cooke, Vesselina G, Korn, Joshua M, Stegmeier, Frank
Published in Nature medicine (01.05.2015)
Published in Nature medicine (01.05.2015)
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Integrated Genomic Analysis of Human Glioblastoma Multiforme
Parsons, D. Williams, Jones, Siân, Zhang, Xiaosong, Lin, Jimmy Cheng-Ho, Leary, Rebecca J, Angenendt, Philipp, Mankoo, Parminder, Carter, Hannah, Siu, I. Mei, Gallia, Gary L, Olivi, Alessandro, McLendon, Roger, Rasheed, B. Ahmed, Keir, Stephen, Nikolskaya, Tatiana, Nikolsky, Yuri, Busam, Dana A, Tekleab, Hanna, Diaz, Luis A. Jr, Hartigan, James, Smith, Doug R, Strausberg, Robert L, Marie, Suely Kazue Nagahashi, Shinjo, Sueli Mieko Oba, Yan, Hai, Riggins, Gregory J, Bigner, Darell D, Karchin, Rachel, Papadopoulos, Nick, Parmigiani, Giovanni, Vogelstein, Bert, Velculescu, Victor E, Kinzler, Kenneth W
Published in Science (American Association for the Advancement of Science) (26.09.2008)
Published in Science (American Association for the Advancement of Science) (26.09.2008)
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Journal Article
Development of personalized tumor biomarkers using massively parallel sequencing
Leary, Rebecca J, Kinde, Isaac, Diehl, Frank, Schmidt, Kerstin, Clouser, Chris, Duncan, Cisilya, Antipova, Alena, Lee, Clarence, McKernan, Kevin, De La Vega, Francisco M, Kinzler, Kenneth W, Vogelstein, Bert, Diaz, Jr, Luis A, Velculescu, Victor E
Published in Science translational medicine (24.02.2010)
Published in Science translational medicine (24.02.2010)
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Journal Article
SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer
BLACKFORD, Amanda, SERRANO, Oscar K, GOGGINS, Michael, JAFFEE, Elizabeth M, LACOBUZIO- DONAHUE, ChristineA, MAITRA, Anirban, CAMERON, John L, OLINO, Kelly, SCHULICK, Richard, WINTER, Jordan, HERMAN, Joseph M, LAHERU, Daniel, WOLFGANG, Christopher L, KLEIN, Alison P, VOGELSTEIN, Bert, KINZLER, Kenneth W, VELCULESCU, Victor E, HRUBAN, Ralph H, PARMIGIANI, Giovanni, JONES, Sian, XIAOSONG ZHANG, PARSONS, D. Williams, LIN, Jimmy Cheng-Ho, LEARY, Rebecca J, ESHLEMAN, James R
Published in Clinical cancer research (15.07.2009)
Published in Clinical cancer research (15.07.2009)
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Journal Article
The Colorectal MicroRNAome
Cummins, Jordan M., He, Yiping, Leary, Rebecca J., Pagliarini, Ray, Diaz, Luis A., Sjoblom, Tobias, Barad, Omer, Bentwich, Zvi, Szafranska, Anna E., Labourier, Emmanuel, Raymond, Christopher K., Roberts, Brian S., Juhl, Hartmut, Kinzler, Kenneth W., Vogelstein, Bert, Velculescu, Victor E.
Published in Proceedings of the National Academy of Sciences - PNAS (07.03.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (07.03.2006)
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Journal Article
Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers
Leary, Rebecca J, Lin, Jimmy C, Cummins, Jordan, Boca, Simina, Wood, Laura D, Parsons, D. Williams, Jones, Siân, Sjöblom, Tobias, Park, Ben-Ho, Parsons, Ramon, Willis, Joseph, Dawson, Dawn, Willson, James K.V, Nikolskaya, Tatiana, Nikolsky, Yuri, Kopelovich, Levy, Papadopoulos, Nick, Pennacchio, Len A, Wang, Tian-Li, Markowitz, Sanford D, Parmigiani, Giovanni, Kinzler, Kenneth W, Vogelstein, Bert, Velculescu, Victor E
Published in Proceedings of the National Academy of Sciences - PNAS (21.10.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (21.10.2008)
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Tracking the Evolution of Resistance to ALK Tyrosine Kinase Inhibitors through Longitudinal Analysis of Circulating Tumor DNA
Dagogo-Jack, Ibiayi, Brannon, A Rose, Ferris, Lorin A, Campbell, Catarina D, Lin, Jessica J, Schultz, Katherine R, Ackil, Jennifer, Stevens, Sara, Dardaei, Leila, Yoda, Satoshi, Hubbeling, Harper, Digumarthy, Subba R, Riester, Markus, Hata, Aaron N, Sequist, Lecia V, Lennes, Inga T, Iafrate, A John, Heist, Rebecca S, Azzoli, Christopher G, Farago, Anna F, Engelman, Jeffrey A, Lennerz, Jochen K, Benes, Cyril H, Leary, Rebecca J, Shaw, Alice T, Gainor, Justin F
Published in JCO precision oncology (2018)
Published in JCO precision oncology (2018)
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Liquid Biopsy Profiling with Multiple Tests in Patients with Metastatic Breast Cancer
Higa, Nikki, Welter, Lisa, Xu, Liya, Kolatkar, Anand, Bramlett, Kelli S., Gjoerup, Ole V., Graf, Ryon, Huang, Richard S.P., Leary, Rebecca J., Lee, Young, Perkins, Jeremy G., Riker, Adam I., Singh, Angad P., Tafra, Lorraine, Tweed, Carol K., Shriver, Craig D., Hicks, James, Kuhn, Peter
Published in Journal of Molecular Pathology (01.06.2024)
Published in Journal of Molecular Pathology (01.06.2024)
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Journal Article
High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response
Gao, Hui, Korn, Joshua M, Ferretti, Stéphane, Monahan, John E, Wang, Youzhen, Singh, Mallika, Zhang, Chao, Schnell, Christian, Yang, Guizhi, Zhang, Yun, Balbin, O Alejandro, Barbe, Stéphanie, Cai, Hongbo, Casey, Fergal, Chatterjee, Susmita, Chiang, Derek Y, Chuai, Shannon, Cogan, Shawn M, Collins, Scott D, Dammassa, Ernesta, Ebel, Nicolas, Embry, Millicent, Green, John, Kauffmann, Audrey, Kowal, Colleen, Leary, Rebecca J, Lehar, Joseph, Liang, Ying, Loo, Alice, Lorenzana, Edward, Robert McDonald, E, McLaughlin, Margaret E, Merkin, Jason, Meyer, Ronald, Naylor, Tara L, Patawaran, Montesa, Reddy, Anupama, Röelli, Claudia, Ruddy, David A, Salangsang, Fernando, Santacroce, Francesca, Singh, Angad P, Tang, Yan, Tinetto, Walter, Tobler, Sonja, Velazquez, Roberto, Venkatesan, Kavitha, Von Arx, Fabian, Wang, Hui Qin, Wang, Zongyao, Wiesmann, Marion, Wyss, Daniel, Xu, Fiona, Bitter, Hans, Atadja, Peter, Lees, Emma, Hofmann, Francesco, Li, En, Keen, Nicholas, Cozens, Robert, Jensen, Michael Rugaard, Pryer, Nancy K, Williams, Juliet A, Sellers, William R
Published in Nature medicine (01.11.2015)
Published in Nature medicine (01.11.2015)
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Journal Article
Detection of chromosomal alterations in the circulation of cancer patients with whole-genome sequencing
Leary, Rebecca J, Sausen, Mark, Kinde, Isaac, Papadopoulos, Nickolas, Carpten, John D, Craig, David, O'Shaughnessy, Joyce, Kinzler, Kenneth W, Parmigiani, Giovanni, Vogelstein, Bert, Diaz, Jr, Luis A, Velculescu, Victor E
Published in Science translational medicine (28.11.2012)
Published in Science translational medicine (28.11.2012)
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Journal Article
Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma
Sausen, Mark, Leary, Rebecca J, Jones, Siân, Wu, Jian, Reynolds, C Patrick, Liu, Xueyuan, Blackford, Amanda, Parmigiani, Giovanni, Diaz, Luis A, Papadopoulos, Nickolas, Vogelstein, Bert, Kinzler, Kenneth W, Velculescu, Victor E, Hogarty, Michael D
Published in Nature genetics (01.01.2013)
Published in Nature genetics (01.01.2013)
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Journal Article
Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients
Sausen, Mark, Phallen, Jillian, Adleff, Vilmos, Jones, Siân, Leary, Rebecca J., Barrett, Michael T., Anagnostou, Valsamo, Parpart-Li, Sonya, Murphy, Derek, Kay Li, Qing, Hruban, Carolyn A., Scharpf, Rob, White, James R., O’Dwyer, Peter J., Allen, Peter J., Eshleman, James R., Thompson, Craig B., Klimstra, David S., Linehan, David C., Maitra, Anirban, Hruban, Ralph H., Diaz, Luis A., Von Hoff, Daniel D., Johansen, Julia S., Drebin, Jeffrey A., Velculescu, Victor E.
Published in Nature communications (07.07.2015)
Published in Nature communications (07.07.2015)
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Journal Article
Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism
Mirzaa, Ghayda M, Campbell, Catarina D, Solovieff, Nadia, Goold, Carleton, Jansen, Laura A, Menon, Suchithra, Timms, Andrew E, Conti, Valerio, Biag, Jonathan D, Adams, Carissa, Boyle, Evan August, Collins, Sarah, Ishak, Gisele, Poliachik, Sandra, Girisha, Katta M, Yeung, Kit San, Chung, Brian Hon Yin, Rahikkala, Elisa, Gunter, Sonya A, McDaniel, Sharon S, Macmurdo, Colleen Forsyth, Bernstein, Jonathan A, Martin, Beth, Leary, Rebecca, Mahan, Scott, Liu, Shanming, Weaver, Molly, Doerschner, Michael, Jhangiani, Shalini, Muzny, Donna M, Boerwinkle, Eric, Gibbs, Richard A, Lupski, James R, Shendure, Jay, Saneto, Russell P, Novotny, Edward J, Wilson, Christopher J, Sellers, William R, Morrissey, Michael, Hevner, Robert F, Ojemann, Jeffrey G, Guerrini, Renzo, Murphy, Leon O, Winckler, Wendy, Dobyns, William B
Published in JAMA neurology (01.07.2016)
Published in JAMA neurology (01.07.2016)
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Clonal hematopoiesis detection in patients with cancer using cell-free DNA sequencing
Fairchild, Lauren, Whalen, Jeanne, D'Aco, Katie, Wu, Jincheng, Gustafson, Carroll B, Solovieff, Nadia, Su, Fei, Leary, Rebecca J, Campbell, Catarina D, Balbin, O Alejandro
Published in Science translational medicine (29.03.2023)
Published in Science translational medicine (29.03.2023)
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Journal Article
Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses
Jones, Siân, Zhang, Xiaosong, Parsons, D. Williams, Lin, Jimmy Cheng-Ho, Leary, Rebecca J, Angenendt, Philipp, Mankoo, Parminder, Carter, Hannah, Kamiyama, Hirohiko, Jimeno, Antonio, Hong, Seung-Mo, Fu, Baojin, Lin, Ming-Tseh, Calhoun, Eric S, Kamiyama, Mihoko, Walter, Kimberly, Nikolskaya, Tatiana, Nikolsky, Yuri, Hartigan, James, Smith, Douglas R, Hidalgo, Manuel, Leach, Steven D, Klein, Alison P, Jaffee, Elizabeth M, Goggins, Michael, Maitra, Anirban, Iacobuzio-Donahue, Christine, Eshleman, James R, Kern, Scott E, Hruban, Ralph H, Karchin, Rachel, Papadopoulos, Nickolas, Parmigiani, Giovanni, Vogelstein, Bert, Velculescu, Victor E, Kinzler, Kenneth W
Published in Science (American Association for the Advancement of Science) (26.09.2008)
Published in Science (American Association for the Advancement of Science) (26.09.2008)
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Journal Article
Identification of microbial DNA in human cancer
Duncan, Christopher G, Leary, Rebecca J, Lin, Jimmy Cheng-Ho, Cummins, Jordan, Di, Chunhui, Schaefer, Carl F, Wang, Tian-Li, Riggins, Gregory J, Edwards, Jennifer, Bigner, Darell, Kopelovich, Levy, Vogelstein, Bert, Kinzler, Kenneth W, Velculescu, Victor E, Yan, Hai
Published in BMC medical genomics (08.05.2009)
Published in BMC medical genomics (08.05.2009)
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Journal Article
Genetic Mutations Associated with Cigarette Smoking in Pancreatic Cancer
BLACKFORD, Amanda, PARMIGIANI, Giovanni, GOGGINS, Michael, JAFFEE, Elizabeth M, IACOBUZIO-DONAHUE, Christine A, MAITRA, Anirban, KLEIN, Alison, CAMERON, John L, OLINO, Kelly, SCHULICK, Richard, WINTER, Jordan, VOGELSTEIN, Bert, KENSLER, Thomas W, VELCULESCU, Victor E, KINZLER, Kenneth W, HRUBAN, Ralph H, WOLFGANG, Christopher, JONES, Sian, XIAOSONG ZHANG, PARSONS, D. Willams, LIN, Jimmy Cheng-Ho, LEARY, Rebecca J, ESHLEMAN, James R
Published in Cancer research (Chicago, Ill.) (15.04.2009)
Published in Cancer research (Chicago, Ill.) (15.04.2009)
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Journal Article
Cancer detection using whole-genome sequencing of cell free DNA
Leary, Rebecca J, Sausen, Mark, Diaz, Jr, Luis A, Velculescu, Victor E
Published in Oncotarget (01.08.2013)
Published in Oncotarget (01.08.2013)
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