Lipid accumulation induced by APOE4 impairs microglial surveillance of neuronal-network activity
Victor, Matheus B., Leary, Noelle, Luna, Xochitl, Meharena, Hiruy S., Scannail, Aine Ni, Bozzelli, P. Lorenzo, Samaan, George, Murdock, Mitchell H., von Maydell, Djuna, Effenberger, Audrey H., Cerit, Oyku, Wen, Hsin-Lan, Liu, Liwang, Welch, Gwyneth, Bonner, Maeve, Tsai, Li-Huei
Published in Cell stem cell (04.08.2022)
Published in Cell stem cell (04.08.2022)
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Journal Article
Melanoma‐derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes
Leary, Noelle, Walser, Sarina, He, Yuliang, Cousin, Nikola, Pereira, Paulo, Gallo, Alessandro, Collado‐Diaz, Victor, Halin, Cornelia, Garcia‐Silva, Susana, Peinado, Hector, Dieterich, Lothar C.
Published in Journal of extracellular vesicles (01.02.2022)
Published in Journal of extracellular vesicles (01.02.2022)
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Journal Article
Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration
Welch, Gwyneth M, Boix, Carles A, Schmauch, Eloi, Davila-Velderrain, Jose, Victor, Matheus B, Dileep, Vishnu, Bozzelli, P Lorenzo, Su, Qiao, Cheng, Jemmie D, Lee, Audrey, Leary, Noelle S, Pfenning, Andreas R, Kellis, Manolis, Tsai, Li-Huei
Published in Science advances (30.09.2022)
Published in Science advances (30.09.2022)
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Journal Article
Human microglial state dynamics in Alzheimer’s disease progression
Sun, Na, Victor, Matheus B., Park, Yongjin P., Xiong, Xushen, Scannail, Aine Ni, Leary, Noelle, Prosper, Shaniah, Viswanathan, Soujanya, Luna, Xochitl, Boix, Carles A., James, Benjamin T., Tanigawa, Yosuke, Galani, Kyriaki, Mathys, Hansruedi, Jiang, Xueqiao, Ng, Ayesha P., Bennett, David A., Tsai, Li-Huei, Kellis, Manolis
Published in Cell (28.09.2023)
Published in Cell (28.09.2023)
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Journal Article
Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer’s disease pathology
Mathys, Hansruedi, Peng, Zhuyu, Boix, Carles A., Victor, Matheus B., Leary, Noelle, Babu, Sudhagar, Abdelhady, Ghada, Jiang, Xueqiao, Ng, Ayesha P., Ghafari, Kimia, Kunisky, Alexander K., Mantero, Julio, Galani, Kyriaki, Lohia, Vanshika N., Fortier, Gabrielle E., Lotfi, Yasmine, Ivey, Jason, Brown, Hannah P., Patel, Pratham R., Chakraborty, Nehal, Beaudway, Jacob I., Imhoff, Elizabeth J., Keeler, Cameron F., McChesney, Maren M., Patel, Haishal H., Patel, Sahil P., Thai, Megan T., Bennett, David A., Kellis, Manolis, Tsai, Li-Huei
Published in Cell (28.09.2023)
Published in Cell (28.09.2023)
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Journal Article
Multisensory gamma stimulation promotes glymphatic clearance of amyloid
Murdock, Mitchell H., Yang, Cheng-Yi, Sun, Na, Pao, Ping-Chieh, Blanco-Duque, Cristina, Kahn, Martin C., Kim, TaeHyun, Lavoie, Nicolas S., Victor, Matheus B., Islam, Md Rezaul, Galiana, Fabiola, Leary, Noelle, Wang, Sidney, Bubnys, Adele, Ma, Emily, Akay, Leyla A., Sneve, Madison, Qian, Yong, Lai, Cuixin, McCarthy, Michelle M., Kopell, Nancy, Kellis, Manolis, Piatkevich, Kiryl D., Boyden, Edward S., Tsai, Li-Huei
Published in Nature (London) (07.03.2024)
Published in Nature (London) (07.03.2024)
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Journal Article
ELECTROPHYSIOLOGICAL PHENOTYPE CHARACTERIZATION OF HUMAN IPSC-DERIVED DOPAMINERGIC NEURONAL LINES BY MEANS OF HIGH-RESOLUTION MICROELECTRODE ARRAYS
Fiscella, Michele, Leary, Noelle, Acun, Ebru, Ronchi, Silvia, Hierlemann, Andreas
Published in Frontiers in cellular neuroscience (2018)
Published in Frontiers in cellular neuroscience (2018)
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Journal Article
Melanoma-derived microvesicles are taken up by lymph node resident macrophages and lymphatic endothelial cells and induce lymph node remodeling
Gallo, Alessandro, Leary, Noelle, Peinado, Héctor, Dieterich, Lothar
Published in Journal of extracellular vesicles (01.01.2018)
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Published in Journal of extracellular vesicles (01.01.2018)
Journal Article
Single-cell atlas of ABCA7 loss-of-function reveals impaired neuronal respiration via choline-dependent lipid imbalances
von Maydell, Djuna, Wright, Shannon, Bonner, Julia Maeve, Staab, Colin, Spitaleri, Andrea, Liu, Liwang, Pao, Ping-Chieh, Yu, Chung Jong, Scannail, Aine Ni, Li, Mingpei, Boix, Carles A, Mathys, Hansruedi, Leclerc, Guillaume, Menchaca, Gloria Suella, Welch, Gwyneth, Graziosi, Agnese, Leary, Noelle, Samaan, George, Kellis, Manolis, Tsai, Li-Huei
Published in bioRxiv (28.06.2024)
Published in bioRxiv (28.06.2024)
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Journal Article
An aging-sensitive compensatory secretory phospholipase that confers neuroprotection and cognitive resilience
Vicidomini, Cinzia, Goode, Travis D, McAvoy, Kathleen M, Yu, Ruilin, Beveridge, Conor H, Iyer, Sanjay N, Victor, Matheus B, Leary, Noelle, Evans, Liam, Steinbaugh, Michael J, Lai, Zon Weng, Lyon, Marina C, Silvestre, Manuel Rico F S, Bonilla, Gracia, Sadreyev, Ruslan I, Walther, Tobias C, Sui, Shannan Ho, Saido, Takaomi, Yamamoto, Kei, Murakami, Makoto, Tsai, Li-Huei, Chopra, Gaurav, Sahay, Amar
Published in bioRxiv (03.09.2024)
Published in bioRxiv (03.09.2024)
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Journal Article
Lipid Accumulation Induced by APOE4 Impairs Microglial Surveillance of Neuronal-Network Activity
Victor, Matheus B, Leary, Noelle, Luna, Xochitl, Meharena, Hiruy S, P Lorenzo Bozzelli, Samaan, George, Murdock, Mitchell H, Djuna Von Maydell, Effenberger, Audrey H, Cerit, Oyku, Hsin-Lan, Wen, Liu, Liwang, Welch, Gwyneth, Bonner, Maeve, Li-Huei Tsai
Published in bioRxiv (21.03.2022)
Published in bioRxiv (21.03.2022)
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