Phase I clinical trial of an intranodally administered mRNA-based therapeutic vaccine against HIV-1 infection
Leal, Lorna, Guardo, Alberto C, Morón-López, Sara, Salgado, Maria, Mothe, Beatriz, Heirman, Carlo, Pannus, Pieter, Vanham, Guido, van den Ham, Henk Jan, Gruters, Rob, Andeweg, Arno, Van Meirvenne, Sonja, Pich, Judit, Arnaiz, Joan Albert, Gatell, Josep M, Brander, Christian, Thielemans, Kris, Martínez-Picado, Javier, Plana, Montserrat, García, Felipe
Published in AIDS (London) (13.11.2018)
Published in AIDS (London) (13.11.2018)
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Journal Article
Optimization and validation of an ELISA assay for the determination of antibody responses to CN54gp140 and AIDSVAX BE for use in the Phase IIb PrEPVacc vaccine trial
Ben Gombe, Claire Streatfield, Lorna Leal, Solomon Opio, Sarah Joseph, Jonathan Weber, Jonathan Hare, Pontiano Kaleebu, Jennifer Serwanga
Published in PloS one (03.11.2022)
Published in PloS one (03.11.2022)
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Journal Article
Optimization and validation of an ELISA assay for the determination of antibody responses to CN54gp140 and AIDSVAX BE for use in the Phase IIb PrEPVacc vaccine trial
Gombe, Ben, Streatfield, Claire, Leal, Lorna, Opio, Solomon, Joseph, Sarah, Weber, Jonathan, Hare, Jonathan, Kaleebu, Pontiano, Serwanga, Jennifer
Published in PloS one (03.11.2022)
Published in PloS one (03.11.2022)
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Journal Article
In the Era of mRNA Vaccines, Is There Any Hope for HIV Functional Cure?
Esteban, Ignasi, Pastor-Quiñones, Carmen, Usero, Lorena, Plana, Montserrat, García, Felipe, Leal, Lorna
Published in Viruses (18.03.2021)
Published in Viruses (18.03.2021)
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Journal Article
New challenges in therapeutic vaccines against HIV infection
Leal, Lorna, Lucero, Constanza, Gatell, Josep M, Gallart, Teresa, Plana, Montserrat, García, Felipe
Published in Expert review of vaccines (03.06.2017)
Published in Expert review of vaccines (03.06.2017)
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Journal Article
Adherence to a Supplemented Mediterranean Diet Drives Changes in the Gut Microbiota of HIV-1-Infected Individuals
Pastor-Ibáñez, Roque, Blanco-Heredia, Juan, Etcheverry, Florencia, Sánchez-Palomino, Sonsoles, Díez-Fuertes, Francisco, Casas, Rosa, Navarrete-Muñoz, María Ángeles, Castro-Barquero, Sara, Lucero, Constanza, Fernández, Irene, Leal, Lorna, Benito, José Miguel, Noguera-Julian, Marc, Paredes, Roger, Rallón, Norma, Estruch, Ramón, Torrents, David, García, Felipe
Published in Nutrients (30.03.2021)
Published in Nutrients (30.03.2021)
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Journal Article
iHIVARNA phase IIa, a randomized, placebo-controlled, double-blinded trial to evaluate the safety and immunogenicity of iHIVARNA-01 in chronically HIV-infected patients under stable combined antiretroviral therapy
de Jong, Wesley, Aerts, Joeri, Allard, Sabine, Brander, Christian, Buyze, Jozefien, Florence, Eric, van Gorp, Eric, Vanham, Guido, Leal, Lorna, Mothe, Beatriz, Thielemans, Kris, Plana, Montse, Garcia, Félipe, Gruters, Rob
Published in Current controlled trials in cardiovascular medicine (17.06.2019)
Published in Current controlled trials in cardiovascular medicine (17.06.2019)
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Journal Article
Antiretroviral Therapy Interruption (ATI) in HIV-1 Infected Patients Participating in Therapeutic Vaccine Trials: Surrogate Markers of Virological Response
Leal, Lorna, Fehér, Csaba, Richart, Valèria, Torres, Berta, García, Felipe
Published in Vaccines (Basel) (05.08.2020)
Published in Vaccines (Basel) (05.08.2020)
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Journal Article
The Combination of an mRNA Immunogen, a TLR7 Agonist and a PD1 Blocking Agent Enhances In-Vitro HIV T-Cell Immune Responses
Usero, Lorena, Leal, Lorna, Gómez, Carmen Elena, Miralles, Laia, Aurrecoechea, Elena, Esteban, Ignasi, Torres, Berta, Inciarte, Alexy, Perdiguero, Beatriz, Esteban, Mariano, García, Felipe, Plana, Montserrat
Published in Vaccines (Basel) (28.01.2023)
Published in Vaccines (Basel) (28.01.2023)
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Journal Article
Enhancement of the HIV-1-Specific Immune Response Induced by an mRNA Vaccine through Boosting with a Poxvirus MVA Vector Expressing the Same Antigen
Gómez, Carmen Elena, Perdiguero, Beatriz, Usero, Lorena, Marcos-Villar, Laura, Miralles, Laia, Leal, Lorna, Sorzano, Carlos Óscar S., Sánchez-Corzo, Cristina, Plana, Montserrat, García, Felipe, Esteban, Mariano
Published in Vaccines (Basel) (27.08.2021)
Published in Vaccines (Basel) (27.08.2021)
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Journal Article
Extremely low viral reservoir in treated chronically HIV-1-infected individuals
Gálvez, Cristina, Urrea, Victor, Dalmau, Judith, Jimenez, Montse, Clotet, Bonaventura, Monceaux, Valérie, Huot, Nicolas, Leal, Lorna, González-Soler, Victoria, González-Cao, Maria, Müller-Trutwin, Michaela, Sáez-Cirión, Asier, García, Felipe, Blanco, Julià, Martinez-Picado, Javier, Salgado, Maria
Published in EBioMedicine (01.07.2020)
Published in EBioMedicine (01.07.2020)
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Journal Article
Impact of Transcriptome and Gut Microbiome on the Response of HIV-1 Infected Individuals to a Dendritic Cell-Based HIV Therapeutic Vaccine
Pastor-Ibáñez, Roque, Díez-Fuertes, Francisco, Sánchez-Palomino, Sonsoles, Alcamí, Jose, Plana, Montserrat, Torrents, David, Leal, Lorna, García, Felipe
Published in Vaccines (Basel) (24.06.2021)
Published in Vaccines (Basel) (24.06.2021)
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Journal Article
Pulmonary Infection Caused by Mycobacterium malmoense in a Chronic HIV-Infected Individual Participating in a Therapeutic Vaccine Trial
Marques, Joana Silva, Bodro, Marta, Torres, Berta, García, Felipe, Martínez, José Antonio, Leal, Lorna
Published in Vaccines (Basel) (01.10.2021)
Published in Vaccines (Basel) (01.10.2021)
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Journal Article
Assessment of Human SARS CoV-2-Specific T-Cell Responses Elicited In Vitro by New Computationally Designed mRNA Immunogens (COVARNA)
Esteban, Ignasi, Pastor-Quiñones, Carmen, Usero, Lorena, Aurrecoechea, Elena, Franceschini, Lorenzo, Esprit, Arthur, Gelpí, Josep Lluís, Martínez-Jiménez, Francisco, López-Bigas, Núria, Breckpot, Karine, Thielemans, Kris, Leal, Lorna, Gómez, Carmen Elena, Sisteré-Oró, Marta, Meyerhans, Andreas, Esteban, Mariano, Alonso, María José, García, Felipe, Plana, Montserrat
Published in Vaccines (Basel) (22.12.2023)
Published in Vaccines (Basel) (22.12.2023)
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Journal Article
Correction to: iHIVARNA phase IIa, a randomized, placebo-controlled, double-blinded trial to evaluate the safety and immunogenicity of iHIVARNA-01 in chronically HIV-infected patients under stable combined antiretroviral therapy
de Jong, Wesley, Aerts, Joeri, Allard, Sabine, Brander, Christian, Buyze, Jozefien, Florence, Eric, van Gorp, Eric, Vanham, Guido, Leal, Lorna, Mothe, Beatriz, Thielemans, Kris, Plana, Montse, Garcia, Félipe, Gruters, Rob
Published in Current controlled trials in cardiovascular medicine (13.12.2019)
Published in Current controlled trials in cardiovascular medicine (13.12.2019)
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Journal Article
Highly Efficient Autologous HIV-1 Isolation by Coculturing Macrophage With Enriched CD4 + T Cells From HIV-1 Patients
Xufré, Cristina, González, Tanía, Leal, Lorna, Trubey, Charles M, Lifson, Jeffrey D, Gatell, José María, Alcamí, José, Climent, Núria, García, Felipe, Sánchez-Palomino, Sonsoles
Published in Frontiers in virology (online) (01.04.2022)
Published in Frontiers in virology (online) (01.04.2022)
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Journal Article
Association of Transcriptomic Signatures of Inflammatory Response with Viral Control after Dendritic Cell-Based Therapeutic Vaccination in HIV-1 Infected Individuals
Fehér, Csaba, Pastor-lbáñez, Roque, Leal, Lorna, Plana, Montserrat, Arnedo, Mireia, van den Ham, Henk-Jan, Andeweg, Arno C., Gruters, Rob A., Díez-Fuertes, Francisco, Alcamí, José, Aloy, Patrick, García, Felipe
Published in Vaccines (Basel) (19.07.2021)
Published in Vaccines (Basel) (19.07.2021)
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Journal Article
Monocytes Phenotype and Cytokine Production in Human Immunodeficiency Virus-1 Infected Patients Receiving a Modified Vaccinia Ankara-Based HIV-1 Vaccine: Relationship to CD300 Molecules Expression
Vitallé, Joana, Zenarruzabeitia, Olatz, Terrén, Iñigo, Plana, Montserrat, Guardo, Alberto C, Leal, Lorna, Peña, José, García, Felipe, Borrego, Francisco
Published in Frontiers in immunology (21.07.2017)
Published in Frontiers in immunology (21.07.2017)
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Journal Article
Differential miRNA plasma profiles associated with the spontaneous loss of HIV‐1 control: miR‐199a‐3p and its potential role as a biomarker for quick screening of elite controllers
Masip, Jenifer, Gasca‐Capote, Carmen, Jimenez‐Leon, María Reyes, Peraire, Joaquim, Perez‐Gomez, Alberto, Alba, Verónica, Malo, Ana‐Irene, Leal, Lorna, Martín, Carmen Rodríguez, Rallón, Norma, Viladés, Consuelo, Olona, Montserrat, Vidal, Francesc, Ruiz‐Mateos, Ezequiel, Rull, Anna
Published in Clinical and translational medicine (01.07.2021)
Published in Clinical and translational medicine (01.07.2021)
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Journal Article
Comparison of Safety and Vector-Specific Immune Responses in Healthy and HIV-Infected Populations Vaccinated with MVA-B
Couto, Elvira, Diaz-Brito, Vicenç, Mothe, Beatriz, Guardo, Alberto C, Fernandez, Irene, Ugarte, Ainoa, Etcheverry, Flor, Gómez, Carmen E, Esteban, Mariano, Pich, Judit, Arnaiz, Joan Albert, López Bernaldo de Quirós, Juan Carlos, Brander, Christian, Plana, Montserrat, García, Felipe, Leal, Lorna
Published in Vaccines (Basel) (07.11.2019)
Published in Vaccines (Basel) (07.11.2019)
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Journal Article