Base-Catalyzed Aryl-B(OH)2 Protodeboronation Revisited: From Concerted Proton Transfer to Liberation of a Transient Aryl Anion
Cox, Paul A, Reid, Marc, Leach, Andrew G, Campbell, Andrew D, King, Edward J, Lloyd-Jones, Guy C
Published in Journal of the American Chemical Society (20.09.2017)
Published in Journal of the American Chemical Society (20.09.2017)
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STINGel: Controlled release of a cyclic dinucleotide for enhanced cancer immunotherapy
Leach, David G., Dharmaraj, Neeraja, Piotrowski, Stacey L., Lopez-Silva, Tania L., Lei, Yu L., Sikora, Andrew G., Young, Simon, Hartgerink, Jeffrey D.
Published in Biomaterials (01.05.2018)
Published in Biomaterials (01.05.2018)
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Chemical functionality of multidomain peptide hydrogels governs early host immune response
Lopez-Silva, Tania L., Leach, David G., Azares, Alon, Li, I-Che, Woodside, Darren G., Hartgerink, Jeffrey D.
Published in Biomaterials (01.02.2020)
Published in Biomaterials (01.02.2020)
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Sequence-Specific, Nanomolar Peptide Binding via Cucurbit[8]uril-Induced Folding and Inclusion of Neighboring Side Chains
Smith, Lauren C, Leach, David G, Blaylock, Brittney E, Ali, Omar A, Urbach, Adam R
Published in Journal of the American Chemical Society (18.03.2015)
Published in Journal of the American Chemical Society (18.03.2015)
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Matched Molecular Pair Analysis in drug discovery
Dossetter, Alexander G., Griffen, Edward J., Leach, Andrew G.
Published in Drug discovery today (01.08.2013)
Published in Drug discovery today (01.08.2013)
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N‑Heterocyclic Carbene-Mediated Microfluidic Oxidative Electrosynthesis of Amides from Aldehydes
Green, Robert A, Pletcher, Derek, Leach, Stuart G, Brown, Richard C. D
Published in Organic letters (04.03.2016)
Published in Organic letters (04.03.2016)
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Difluorocarbene Generation from TMSCF3: Kinetics and Mechanism of NaI-Mediated and Si-Induced Anionic Chain Reactions
García-Domínguez, Andrés, West, Thomas H, Primozic, Johann J, Grant, Katie M, Johnston, Craig P, Cumming, Grant G, Leach, Andrew G, Lloyd-Jones, Guy C
Published in Journal of the American Chemical Society (26.08.2020)
Published in Journal of the American Chemical Society (26.08.2020)
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Protodeboronation of (Hetero)Arylboronic Esters: Direct versus Prehydrolytic Pathways and Self-/Auto-Catalysis
Hayes, Hannah L. D, Wei, Ran, Assante, Michele, Geogheghan, Katherine J, Jin, Na, Tomasi, Simone, Noonan, Gary, Leach, Andrew G, Lloyd-Jones, Guy C
Published in Journal of the American Chemical Society (15.09.2021)
Published in Journal of the American Chemical Society (15.09.2021)
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Anion-Initiated Trifluoromethylation by TMSCF3: Deconvolution of the Siliconate–Carbanion Dichotomy by Stopped-Flow NMR/IR
Johnston, Craig P, West, Thomas H, Dooley, Ruth E, Reid, Marc, Jones, Ariana B, King, Edward J, Leach, Andrew G, Lloyd-Jones, Guy C
Published in Journal of the American Chemical Society (05.09.2018)
Published in Journal of the American Chemical Society (05.09.2018)
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Fumarate induces redox-dependent senescence by modifying glutathione metabolism
Zheng, Liang, Cardaci, Simone, Jerby, Livnat, MacKenzie, Elaine D, Sciacovelli, Marco, Johnson, T Isaac, Gaude, Edoardo, King, Ayala, Leach, Joshua D G, Edrada-Ebel, RuAngelie, Hedley, Ann, Morrice, Nicholas A, Kalna, Gabriela, Blyth, Karen, Ruppin, Eytan, Frezza, Christian, Gottlieb, Eyal
Published in Nature communications (23.01.2015)
Published in Nature communications (23.01.2015)
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Learning Medicinal Chemistry Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) Rules from Cross-Company Matched Molecular Pairs Analysis (MMPA)
Kramer, Christian, Ting, Attilla, Zheng, Hao, Hert, Jérôme, Schindler, Torsten, Stahl, Martin, Robb, Graeme, Crawford, James J, Blaney, Jeff, Montague, Shane, Leach, Andrew G, Dossetter, Al G, Griffen, Ed J
Published in Journal of medicinal chemistry (26.04.2018)
Published in Journal of medicinal chemistry (26.04.2018)
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MIDA boronates are hydrolysed fast and slow by two different mechanisms
Gonzalez, Jorge A, Ogba, O Maduka, Morehouse, Gregory F, Rosson, Nicholas, Houk, Kendall N, Leach, Andrew G, Cheong, Paul H-Y, Burke, Martin D, Lloyd-Jones, Guy C
Published in Nature chemistry (01.11.2016)
Published in Nature chemistry (01.11.2016)
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N‑Heterocyclic Carbene-Mediated Oxidative Electrosynthesis of Esters in a Microflow Cell
Green, Robert A, Pletcher, Derek, Leach, Stuart G, Brown, Richard C. D
Published in Organic letters (02.07.2015)
Published in Organic letters (02.07.2015)
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Binding Affinities of Host-Guest, Protein-Ligand, and Protein-Transition-State Complexes
Houk, K. N., Leach, Andrew G., Kim, Susanna P., Zhang, Xiyun
Published in Angewandte Chemie (International ed.) (20.10.2003)
Published in Angewandte Chemie (International ed.) (20.10.2003)
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X-ray crystallographic, luminescence and NMR studies of phenacyldiphenylphosphine oxide with the Ln(iii) ions Sm, Eu, Gd, Tb and Dy
G Leach, Erin, Shady, Justin R, Boyden, Adam C, Emig, Anne-Lise, Henry, Alyssa T, Connor, Emily K, Staples, Richard J, Schaertel, Stephanie, Werner, Eric J, Biros, Shannon M
Published in Dalton transactions : an international journal of inorganic chemistry (2017)
Published in Dalton transactions : an international journal of inorganic chemistry (2017)
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Catalytic Enantioselective Synthesis of Heterocyclic Vicinal Fluoroamines by Using Asymmetric Protonation: Method Development and Mechanistic Study
Ashford, Matthew W., Xu, Chao, Molloy, John J., Carpenter‐Warren, Cameron, Slawin, Alexandra M. Z., Leach, Andrew G., Watson, Allan J. B.
Published in Chemistry : a European journal (21.09.2020)
Published in Chemistry : a European journal (21.09.2020)
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