Breaking in and busting out: cell-penetrating peptides and the endosomal escape problem
LeCher, Julia C., Nowak, Scott J., McMurry, Jonathan L.
Published in Biomolecular concepts (26.09.2017)
Published in Biomolecular concepts (26.09.2017)
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Journal Article
Synthesis of 4'-Substituted Carbocyclic Uracil Derivatives and Their Monophosphate Prodrugs as Potential Antiviral Agents
Biteau, Nicolas G, Amichai, Sarah A, Azadi, Niloufar, De, Ramyani, Downs-Bowen, Jessica, Lecher, Julia C, MacBrayer, Tamara, Schinazi, Raymond F, Amblard, Franck
Published in Viruses (01.02.2023)
Published in Viruses (01.02.2023)
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Journal Article
Why Certain Repurposed Drugs Are Unlikely to Be Effective Antivirals to Treat SARS-CoV-2 Infections
Hurwitz, Selwyn J, De, Ramyani, LeCher, Julia C, Downs-Bowen, Jessica A, Goh, Shu Ling, Zandi, Keivan, McBrayer, Tamara, Amblard, Franck, Patel, Dharmeshkumar, Kohler, James J, Bhasin, Manoj, Dobosh, Brian S, Sukhatme, Vikas, Tirouvanziam, Rabindra M, Schinazi, Raymond F
Published in Viruses (01.04.2024)
Published in Viruses (01.04.2024)
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Journal Article
Synthesis of Novel N4-Hydrocytidine Analogs as Potential Anti-SARS-CoV-2 Agents
Amblard, Franck, LeCher, Julia C., De, Ramyani, Goh, Shu Ling, Li, Chengwei, Kasthuri, Mahesh, Biteau, Nicolas, Zhou, Longhu, Tber, Zahira, Downs-Bowen, Jessica, Zandi, Keivan, Schinazi, Raymond F.
Published in Pharmaceuticals (Basel, Switzerland) (14.09.2022)
Published in Pharmaceuticals (Basel, Switzerland) (14.09.2022)
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Journal Article
Utilization of a cell‐penetrating peptide‐adaptor for delivery of human papillomavirus protein E2 into cervical cancer cells to arrest cell growth and promote cell death
LeCher, Julia C., Didier, Hope L., Dickson, Robert L., Slaughter, Lauren R., Bejarano, Juana C., Ho, Steven, Nowak, Scott J., Chrestensen, Carol A., McMurry, Jonathan L.
Published in Cancer reports (01.05.2023)
Published in Cancer reports (01.05.2023)
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Journal Article
Comparison of anti-SARS-CoV-2 activity and intracellular metabolism of remdesivir and its parent nucleoside
Tao, Sijia, Zandi, Keivan, Bassit, Leda, Ong, Yee Tsuey, Verma, Kiran, Liu, Peng, Downs-Bowen, Jessica A., McBrayer, Tamara, LeCher, Julia C., Kohler, James J., Tedbury, Philip R., Kim, Baek, Amblard, Franck, Sarafianos, Stefan G., Schinazi, Raymond F.
Published in Current research in pharmacology and drug discovery (01.01.2021)
Published in Current research in pharmacology and drug discovery (01.01.2021)
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Discovery of a 2'-Fluoro,2'-Bromouridine Phosphoramidate Prodrug Exhibiting Anti-Yellow Fever Virus Activity in Culture and in Mice
LeCher, Julia C, Zandi, Keivan, Costa, Vivian Vasconcelos, Amblard, Franck, Tao, Sijia, Patel, Dharmeshkumar, Lee, Sujin, da Silva Santos, Felipe Rocha, Goncalves, Matheus Rodrigues, Queroz-Junior, Celso Martins, Marim, Fernanda Martins, Musall, Katie, Goh, Shu Ling, McBrayer, Tamara, Downs-Bowen, Jessica, De, Ramyani, Azadi, Niloufar, Kohler, James, Teixeira, Mauro Martins, Schinazi, Raymond F
Published in Microorganisms (Basel) (22.10.2022)
Published in Microorganisms (Basel) (22.10.2022)
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Journal Article
Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease
Amblard, Franck, LeCher, Julia C., De, Ramyani, Zhou, Shaoman, Liu, Peng, Goh, Shu Ling, Tao, Sijia, Patel, Dharmeshkumar, Downs-Bowen, Jessica, Zandi, Keivan, Zhang, Huanchun, Chaudhry, Gitika, McBrayer, Tamara, Muczynski, Michael, Al-Homoudi, Abdullah, Engel, Joseph, Lan, Shuiyun, Sarafianos, Stefan G., Kovari, Ladislau C., Schinazi, Raymond F.
Published in European journal of medicinal chemistry (15.03.2024)
Published in European journal of medicinal chemistry (15.03.2024)
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Journal Article
Stably-Inverted Apical-Out Human Upper Airway Organoids for SARS-CoV-2 Infection and Therapeutic Testing
Lee, Ji-Hoon, LeCher, Julia C, Parigoris, Eric, Shinagawa, Noriyuki, Sentosa, Jason, Manfredi, Candela, Goh, Shu Ling, De, Ramyani, Tao, Sijia, Zandi, Keivan, Amblard, Franck, Sorscher, Eric J, Spence, Jason R, Tirouvanziam, Rabindra, Schinazi, Raymond F, Takayama, Shuichi
Published in bioRxiv (04.01.2024)
Published in bioRxiv (04.01.2024)
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Paper
Synthesis of Novel IN/I[sup.4]-Hydrocytidine Analogs as Potential Anti-SARS-CoV-2 Agents
Amblard, Franck, LeCher, Julia C, De, Ramyani, Goh, Shu Ling, Li, Chengwei, Kasthuri, Mahesh, Biteau, Nicolas, Zhou, Longhu, Tber, Zahira, Downs-Bowen, Jessica, Zandi, Keivan, Schinazi, Raymond F
Published in Pharmaceuticals (Basel, Switzerland) (01.09.2022)
Published in Pharmaceuticals (Basel, Switzerland) (01.09.2022)
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Journal Article
Development of robust antiviral assays using relevant apical-out human airway organoids
Lee, Ji-Hoon, LeCher, Julia C, Parigoris, Eric, Shinagawa, Noriyuki, Sentosa, Jason, Manfredi, Candela, Goh, Shu Ling, De, Ramyani, Tao, Sijia, Zandi, Keivan, Amblard, Franck, Sorscher, Eric J, Spence, Jason R, Tirouvanziam, Rabindra, Schinazi, Raymond F, Takayama, Shuichi
Published in bioRxiv (12.07.2024)
Published in bioRxiv (12.07.2024)
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