Dual blockade of IL-4 and IL-13 with dupilumab, an IL-4Rα antibody, is required to broadly inhibit type 2 inflammation
Le Floch-ramondou, Audrey, Nagashima, Kirsten, Scott, George, Birchard, Dylan, Asrat, Seblewongel, Bai, Yu, Lim, Wei Keat, Murphy, Andrew, Sleeman, Matthew, Orengo, Jamie
Published in Journal of allergy and clinical immunology (01.02.2020)
Published in Journal of allergy and clinical immunology (01.02.2020)
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Journal Article
Blockade of Common Gamma Chain Cytokine Signaling with REGN7257, an Interleukin 2 Receptor Gamma (IL2RG) Monoclonal Antibody, in Combination with Costimulatory Blockers Delayed Skin Graft Rejection in Mice
Le Floch-Ramondou, Audrey, Scott, George, Chen, Wen-Chi, Nagashima, Kirsten, Murphy, Andrew, Sleeman, Matthew, Orengo, Jamie
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
IL-4 And IL-13 Have Distinct And Overlapping Effects On Key Cell Types Involved In The Pathobiology Of Atopic Dermatitis
Srivatsan, Subhashini, Le Floch-ramondou, Audrey, Nagashima, Kirsten, Buonagurio, Brianna, Pappatheodorou, Angelos, Lim, Wei Keat, Murphy, Andrew, Sleeman, Matthew, Orengo, Jamie
Published in Journal of allergy and clinical immunology (01.02.2023)
Published in Journal of allergy and clinical immunology (01.02.2023)
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Journal Article
Blockade of Common Gamma Chain Cytokine Signaling with REGN7257, an Interleukin 2 Receptor Gamma (IL2RG) Monoclonal Antibody, Protected Mice from Inflammatory and Autoimmune Diseases
Le Floch-Ramondou, Audrey, Nagashima, Kirsten, Farrales, Pamela, Tay, Amanda, Herbin, Olivier, Ajithdoss, Dharani, Norton, Thomas, Perlee, Lorah, Murphy, Andrew J., Sleeman, Matthew, Orengo, Jamie
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Evaluation of Common Gamma Chain Cytokine Signaling Blockade with REGN7257, an Interleukin 2 Receptor Gamma (IL2RG) Monoclonal Antibody, on Immune Cell Populations in Monkey and Human
Le Floch-Ramondou, Audrey, Nagashima, Kirsten, Gayvert, Kaitlyn, Pan, Hao, Korgaonkar, Chandrashekhar, Shakil, Hassan, Ullman, Erica, Norton, Thomas, Perlee, Lorah, Murphy, Andrew J., Sleeman, Matthew, Orengo, Jamie
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article