Intratumoral Delivery of Plasmid IL12 Via Electroporation Leads to Regression of Injected and Noninjected Tumors in Merkel Cell Carcinoma
Bhatia, Shailender, Longino, Natalie V, Miller, Natalie J, Kulikauskas, Rima, Iyer, Jayasri G, Ibrani, Dafina, Blom, Astrid, Byrd, David R, Parvathaneni, Upendra, Twitty, Christopher G, Campbell, Jean S, Le, Mai H, Gargosky, Sharron, Pierce, Robert H, Heller, Richard, Daud, Adil I, Nghiem, Paul
Published in Clinical cancer research (01.02.2020)
Published in Clinical cancer research (01.02.2020)
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Phase Ib study of the combination of pexidartinib (PLX3397), a CSF-1R inhibitor, and paclitaxel in patients with advanced solid tumors
Wesolowski, Robert, Sharma, Neelesh, Reebel, Laura, Rodal, Mary Beth, Peck, Alexandra, West, Brian L., Marimuthu, Adhirai, Severson, Paul, Karlin, David A., Dowlati, Afshin, Le, Mai H., Coussens, Lisa M., Rugo, Hope S.
Published in Therapeutic advances in medical oncology (01.06.2019)
Published in Therapeutic advances in medical oncology (01.06.2019)
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Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12
Garris, Christopher S., Arlauckas, Sean P., Kohler, Rainer H., Trefny, Marcel P., Garren, Seth, Piot, Cécile, Engblom, Camilla, Pfirschke, Christina, Siwicki, Marie, Gungabeesoon, Jeremy, Freeman, Gordon J., Warren, Sarah E., Ong, SuFey, Browning, Erica, Twitty, Christopher G., Pierce, Robert H., Le, Mai H., Algazi, Alain P., Daud, Adil I., Pai, Sara I., Zippelius, Alfred, Weissleder, Ralph, Pittet, Mikael J.
Published in Immunity (Cambridge, Mass.) (18.12.2018)
Published in Immunity (Cambridge, Mass.) (18.12.2018)
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A Phase I Dose-Escalation and Expansion Study of Telaglenastat in Patients with Advanced or Metastatic Solid Tumors
Harding, James J, Telli, Melinda, Munster, Pamela, Voss, Martin H, Infante, Jeffrey R, DeMichele, Angela, Dunphy, Mark, Le, Mai H, Molineaux, Chris, Orford, Keith, Parlati, Frank, Whiting, Sam H, Bennett, Mark K, Tannir, Nizar M, Meric-Bernstam, Funda
Published in Clinical cancer research (15.09.2021)
Published in Clinical cancer research (15.09.2021)
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Intratumoral Plasmid IL12 Electroporation Therapy in Patients with Advanced Melanoma Induces Systemic and Intratumoral T-cell Responses
Greaney, Samantha K, Algazi, Alain P, Tsai, Katy K, Takamura, Kathryn T, Chen, Lawrence, Twitty, Christopher G, Zhang, Li, Paciorek, Alan, Pierce, Robert H, Le, Mai H, Daud, Adil I, Fong, Lawrence
Published in Cancer immunology research (01.02.2020)
Published in Cancer immunology research (01.02.2020)
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Characterizing and Overriding the Structural Mechanism of the Quizartinib-Resistant FLT3 "Gatekeeper" F691L Mutation with PLX3397
Smith, Catherine C, Zhang, Chao, Lin, Kimberly C, Lasater, Elisabeth A, Zhang, Ying, Massi, Evan, Damon, Lauren E, Pendleton, Matthew, Bashir, Ali, Sebra, Robert, Perl, Alexander, Kasarskis, Andrew, Shellooe, Rafe, Tsang, Garson, Carias, Heidi, Powell, Ben, Burton, Elizabeth A, Matusow, Bernice, Zhang, Jiazhong, Spevak, Wayne, Ibrahim, Prabha N, Le, Mai H, Hsu, Henry H, Habets, Gaston, West, Brian L, Bollag, Gideon, Shah, Neil P
Published in Cancer discovery (01.06.2015)
Published in Cancer discovery (01.06.2015)
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Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12
Garris, Christopher S., Arlauckas, Sean P., Kohler, Rainer H., Trefny, Marcel P., Garren, Seth, Piot, Cécile, Engblom, Camilla, Pfirschke, Christina, Siwicki, Marie, Gungabeesoon, Jeremy, Freeman, Gordon J., Warren, Sarah E., Ong, SuFey, Browning, Erica, Twitty, Christopher G., Pierce, Robert H., Le, Mai H., Algazi, Alain P., Daud, Adil I., Pai, Sara I., Zippelius, Alfred, Weissleder, Ralph, Pittet, Mikael J.
Published in Immunity (Cambridge, Mass.) (13.09.2022)
Published in Immunity (Cambridge, Mass.) (13.09.2022)
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Recurrent Mutations in Cyclin D3 Confer Clinical Resistance to FLT3 Inhibitors in Acute Myeloid Leukemia
Smith, Catherine C, Viny, Aaron D, Massi, Evan, Kandoth, Cyriac, Socci, Nicholas D, Rapaport, Franck, Najm, Matthieu, Medina-Martinez, Juan S, Papaemmanuil, Elli, Tarver, Theodore C, Hsu, Henry H, Le, Mai H, West, Brian, Bollag, Gideon, Taylor, Barry S, Levine, Ross L, Shah, Neil P
Published in Clinical cancer research (15.07.2021)
Published in Clinical cancer research (15.07.2021)
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Melanoma treatment with intratumoral electroporation of tavokinogene telseplasmid (pIL-12, tavokinogene telseplasmid)
Canton, David A, Shirley, Shawna, Wright, Jocelyn, Connolly, Richard, Burkart, Christoph, Mukhopadhyay, Anandaroop, Twitty, Chris, Qattan, Kristen E, Campbell, Jean S, Le, Mai H, Pierce, Robert H, Gargosky, Sharron, Daud, Adil, Algazi, Alain
Published in Immunotherapy (01.12.2017)
Published in Immunotherapy (01.12.2017)
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A phase 1/2 study of the oral FLT3 inhibitor pexidartinib in relapsed/refractory FLT3-ITD–mutant acute myeloid leukemia
Smith, Catherine C., Levis, Mark J., Frankfurt, Olga, Pagel, John M., Roboz, Gail J., Stone, Richard M., Wang, Eunice S., Severson, Paul L., West, Brian L., Le, Mai H., Kayser, Sabine, Lam, Bao, Hsu, Henry H., Zhang, Chao, Bollag, Gideon, Perl, Alexander E.
Published in Blood advances (28.04.2020)
Published in Blood advances (28.04.2020)
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Preclinical and Clinical Resistance Mechanisms To The Investigational Selective FLT3 Inhibitor PLX3397 In FLT3-ITD+ Acute Myeloid Leukemia (AML)
Smith, Catherine C, Lin, Kimberly, Lasater, Elisabeth, Stewart, Whitney, Damon, Lauren E, Kasarskis, Andrew, Bashir, Ali, Pendleton, Matthew, Sebra, Robert, Perl, Alexander E, Le, Mai H, Zhang, Chao, West, Brian, Shah, Neil P.
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Abstract CT134: Intratumoral electroporation of plasmid IL-12 can prime response to anti-PD1PD-L1 blockade in patients with Stage IIIIV-M1a melanoma
Algazi, Alain, Tsai, Katy K, Takamura, Kathryn T, Chen, Lawrence, Twitty, Chris, Dwyer, Mary, Greaney, Samantha, Diep, Tu, Pierce, Robert H, Le, Mai H, Fong, Lawrence, Daud, Adil
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract CT134: Intratumoral electroporation of plasmid IL-12 can prime response to anti-PD1/PD-L1 blockade in patients with Stage III/IV-M1a melanoma
Algazi, Alain, Tsai, Katy K., Takamura, Kathryn T., Chen, Lawrence, Twitty, Chris, Dwyer, Mary, Greaney, Samantha, Diep, Tu, Pierce, Robert H., Le, Mai H., Fong, Lawrence, Daud, Adil
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Immune monitoring outcomes of patients with stage III/IV melanoma treated with a combination of pembrolizumab and intratumoral plasmid interleukin 12 (pIL-12)
Algazi, Alain Patrick, Tsai, Katy K., Rosenblum, Michael, Fox, Bernard A., Andtbacka, Robert Hans Ingemar, Li, Amy, Takamura, Kathryn Toshimi, Dwyer, Mary, Browning, Erica, Talia, Reneta, Twitty, Chris, Le, Mai H., Gargosky, Sharron, Campbell, Jean S., Ballesteros-Merino, Carmen, Bifulco, Carlo Bruno, Pierce, Robert, Daud, Adil
Published in Journal of clinical oncology (01.03.2017)
Published in Journal of clinical oncology (01.03.2017)
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A phase 1b study to assess the safety of PLX3397, a CSF-1 receptor inhibitor, and paclitaxel in patients with advanced solid tumors
Sharma, Neelesh, Wesolowski, Robert, Reebel, Laura, Rodal, Mary Beth, Peck, Alexandra, West, Brian, Karlin, David Alan, Dowlati, Afshin, Le, Mai H., Coussens, Lisa M, Rugo, Hope S.
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Safety and tolerability of increasing doses of CB-839, a first-in-class, orally administered small molecule inhibitor of glutaminase, in solid tumors
Harding, James J., Telli, Melinda L., Munster, Pamela N., Le, Mai H., Molineaux, Christopher, Bennett, Mark K., Mittra, Erik, Burris, Howard A., Clark, Amy Sanders, Dunphy, Mark, Meric-Bernstam, Funda, Patel, Manish R., DeMichele, Angela, Infante, Jeffrey R.
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
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Long-Term Treatment and Tolerability of the Novel Proteasome Inhibitor Carfilzomib (CFZ) In Patients with Relapsed and/or Refractory Multiple Myeloma (R/R MM)
Jagannath, Sundar, Vij, Ravi, Kaufman, Jonathan L., Martin, Thomas, Niesvizky, Ruben, Gabrail, Nashat Y, Alsina, Melissa, Wong, Alvin F., Le, Mai H., McCulloch, Leanne, Hannah, Alison L., Kauffman, Michael, diCapua Siegel, David Samuel
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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Carfilzomib: High Single Agent Response Rate with Minimal Neuropathy Even In High-Risk Patients
Vij, Ravi, Kaufman, Jonathan L., Jakubowiak, Andrzej J, Stewart, A. Keith, Jagannath, Sundar, Kukreti, Vishal, McDonagh, Kevin T., Alsina, Melissa, Bahlis, Nizar J, Belch, Andrew, Reu, Frederic J., Gabrail, Nashat Y, Matous, Jeffrey, Vesole, David H., Orlowski, Robert Z., Le, Mai H., Lee, Peter, Wang, Michael, MMRC, The
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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