Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors
Bach, Karsten, Pensa, Sara, Zarocsinceva, Marija, Kania, Katarzyna, Stockis, Julie, Pinaud, Silvain, Lazarus, Kyren A, Shehata, Mona, Simões, Bruno M, Greenhalgh, Alice R, Howell, Sacha J, Clarke, Robert B, Caldas, Carlos, Halim, Timotheus Y F, Marioni, John C, Khaled, Walid T
Published in Nature communications (09.03.2021)
Published in Nature communications (09.03.2021)
Get full text
Journal Article
BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma
Lazarus, Kyren A, Hadi, Fazal, Zambon, Elisabetta, Bach, Karsten, Santolla, Maria-Francesca, Watson, Julie K, Correia, Lucia L, Das, Madhumita, Ugur, Rosemary, Pensa, Sara, Becker, Lukas, Campos, Lia S, Ladds, Graham, Liu, Pentao, Evan, Gerard I, McCaughan, Frank M, Le Quesne, John, Lee, Joo-Hyeon, Calado, Dinis, Khaled, Walid T
Published in Nature communications (20.08.2018)
Published in Nature communications (20.08.2018)
Get full text
Journal Article
Aromatase is a direct target of FOXL2: C134W in granulosa cell tumors via a single highly conserved binding site in the ovarian specific promoter
Fleming, Nicholas I, Knower, Kevin C, Lazarus, Kyren A, Fuller, Peter J, Simpson, Evan R, Clyne, Colin D
Published in PloS one (20.12.2010)
Published in PloS one (20.12.2010)
Get full text
Journal Article
The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma
Coulson, Rhiannon, Liew, Seng H, Connelly, Angela A, Yee, Nicholas S, Deb, Siddhartha, Kumar, Beena, Vargas, Ana C, O'Toole, Sandra A, Parslow, Adam C, Poh, Ashleigh, Putoczki, Tracy, Morrow, Riley J, Alorro, Mariah, Lazarus, Kyren A, Yeap, Evie F W, Walton, Kelly L, Harrison, Craig A, Hannan, Natalie J, George, Amee J, Clyne, Colin D, Ernst, Matthias, Allen, Andrew M, Chand, Ashwini L
Published in Oncotarget (21.03.2017)
Published in Oncotarget (21.03.2017)
Get full text
Journal Article
The orphan nuclear receptor LRH-1 and ERα activate GREB1 expression to induce breast cancer cell proliferation
Chand, Ashwini L, Wijayakumara, Dhilushi D, Knower, Kevin C, Herridge, Kerrie A, Howard, Tamara L, Lazarus, Kyren A, Clyne, Colin D
Published in PloS one (16.02.2012)
Published in PloS one (16.02.2012)
Get full text
Journal Article
Cell-intrinsic differences between human airway epithelial cells from children and adults
Maughan, Elizabeth F., Hynds, Robert E., Pennycuick, Adam, Nigro, Ersilia, Gowers, Kate H.C., Denais, Celine, Gómez-López, Sandra, Lazarus, Kyren A., Orr, Jessica C., Pearce, David R., Clarke, Sarah E., Lee, Dani Do Hyang, Woodall, Maximillian N.J., Masonou, Tereza, Case, Katie-Marie, Teixeira, Vitor H., Hartley, Benjamin E., Hewitt, Richard J., Al Yaghchi, Chadwan, Sandhu, Gurpreet S., Birchall, Martin A., O’Callaghan, Christopher, Smith, Claire M., De Coppi, Paolo, Butler, Colin R., Janes, Sam M.
Published in iScience (18.11.2022)
Published in iScience (18.11.2022)
Get full text
Journal Article
Transformation of naked mole-rat cells
Hadi, Fazal, Kulaberoglu, Yavuz, Lazarus, Kyren A, Bach, Karsten, Ugur, Rosemary, Beattie, Paul, Smith, Ewan St John, Khaled, Walid T
Published in Nature (London) (02.07.2020)
Published in Nature (London) (02.07.2020)
Get full text
Journal Article
A lentiviral toolkit to monitor airway epithelial cell differentiation using bioluminescence
Orr, Jessica C., Laali, Asma, Durrenberger, Pascal F., Lazarus, Kyren A., El Mdawar, Marie-Belle, Janes, Sam M., Hynds, Robert E.
Published in American journal of physiology. Lung cellular and molecular physiology (13.08.2024)
Published in American journal of physiology. Lung cellular and molecular physiology (13.08.2024)
Get full text
Journal Article
Conditional Overexpression of Liver Receptor Homolog-1 in Female Mouse Mammary Epithelium Results in Altered Mammary Morphogenesis via the Induction of TGF-β
Lazarus, Kyren A, Brown, Kristy A, Young, Morag J, Zhao, Zhe, Coulson, Rhiannon S, Chand, Ashwini L, Clyne, Colin D
Published in Endocrinology (Philadelphia) (01.05.2014)
Published in Endocrinology (Philadelphia) (01.05.2014)
Get full text
Journal Article
Oestradiol reduces Liver Receptor Homolog-1 mRNA transcript stability in breast cancer cell lines
Lazarus, Kyren A., Zhao, Zhe, Knower, Kevin C., To, Sarah Q., Chand, Ashwini L., Clyne, Colin D.
Published in Biochemical and biophysical research communications (30.08.2013)
Published in Biochemical and biophysical research communications (30.08.2013)
Get full text
Journal Article
Abstract 76: Liver receptor homologue-1 increases incidence of DMBA-induced mammary tumors
Lazarus, Kyren A., Brown, Kristy, Young, Morag, Cain, Jason, Jayasekara, Samantha, Coulson, Rhiannon, Watkins, Neil, Clyne, Colin, Chand, Ashwini
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Get full text
Journal Article
The Orphan Nuclear Receptor LRH-1 and ER[alpha] Activate GREB1 Expression to Induce Breast Cancer Cell Proliferation
Chand, Ashwini L, Wijayakumara, Dhilushi D, Knower, Kevin C, Herridge, Kerrie A, Howard, Tamara L, Lazarus, Kyren A, Clyne, Colin D
Published in PloS one (16.02.2012)
Published in PloS one (16.02.2012)
Get full text
Journal Article
Cell-intrinsic differences between human airway epithelial cells from children and adults
Maughan, Elizabeth F, Hynds, Robert E, Pennycuick, Adam, Nigro, Ersilia, Gowers, Kate Hc, Denais, Celine, Gómez-López, Sandra, Lazarus, Kyren A, Orr, Jessica C, Pearce, David R, Clarke, Sarah E, Dani Do Hyang Lee, Woodall, Maximillian N J, Masonou, Tereza, Case, Katie-Marie, Teixeira, Vitor Hugo, Hartley, Benjamin E, Hewitt, Richard J, Chadwan Al Yaghchi, Sandhu, Gurpreet S, Birchall, Martin A, O'callaghan, Christopher, Smith, Claire M, De Coppi, Paolo, Butler, Colin R, Janes, Sam M
Published in bioRxiv (28.03.2022)
Published in bioRxiv (28.03.2022)
Get full text
Paper
BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous cell carcinoma
Lazarus, Kyren A, Fazal Hadi, Zambon, Elisabetta, Bach, Karsten, Maria-Francesca Santolla, Watson, Julie K, Correia, Lucia L, Das, Madhumita, Ugur, Rosemary, Pensa, Sara, Becker, Lukas, Campos, Lia S, Ladds, Graham, Liu, Pentao, Gerard, Evan, Mccaughan, Frank, John Le Quesne, Joo-Hyeon, Lee, Calado, Dinis, Khaled, Walid T
Published in bioRxiv (22.11.2017)
Published in bioRxiv (22.11.2017)
Get full text
Paper