Search Results - "Lawrence B. Perez" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Dual Allosteric Inhibition of SHP2 Phosphatase

Dual Allosteric Inhibition of SHP2 Phosphatase

by Fodor, Michelle, Price, Edmund, Wang, Ping, Lu, Hengyu, Argintaru, Andreea, Chen, Zhouliang, Glick, Meir, Hao, Huai-Xiang, Kato, Mitsunori, Koenig, Robert, LaRochelle, Jonathan R, Liu, Gang, McNeill, Eric, Majumdar, Dyuti, Nishiguchi, Gisele A, Perez, Lawrence B, Paris, Gregory, Quinn, Christopher M, Ramsey, Timothy, Sendzik, Martin, Shultz, Michael David, Williams, Sarah L, Stams, Travis, Blacklow, Stephen C, Acker, Michael G, LaMarche, Matthew J
Published in ACS chemical biology (16.03.2018)

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Journal Article

Synthesis and Enzymatic Studies of Bisubstrate Analogues for Farnesyl Diphosphate Synthase

Synthesis and Enzymatic Studies of Bisubstrate Analogues for Farnesyl Diphosphate Synthase

by Ramamoorthy, Gurusankar, Pugh, Mark L, Tian, Bo-Xue, Phan, Richard M, Perez, Lawrence B, Jacobson, Matthew P, Poulter, C. Dale
Published in Journal of organic chemistry (17.04.2015)

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Journal Article

N-Hydroxy-3-phenyl-2-propenamides as Novel Inhibitors of Human Histone Deacetylase with in Vivo Antitumor Activity: Discovery of (2E)-N-Hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824)

N-Hydroxy-3-phenyl-2-propenamides as Novel Inhibitors of Human Histone Deacetylase with in Vivo Antitumor Activity: Discovery of (2E)-N-Hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824)

by Remiszewski, Stacy W, Sambucetti, Lidia C, Bair, Kenneth W, Bontempo, John, Cesarz, David, Chandramouli, Nagarajan, Chen, Ru, Cheung, Min, Cornell-Kennon, Susan, Dean, Karl, Diamantidis, George, France, Dennis, Green, Michael A, Howell, Kobporn Lulu, Kashi, Rina, Kwon, Paul, Lassota, Peter, Martin, Mary S, Mou, Yin, Perez, Lawrence B, Sharma, Sushil, Smith, Troy, Sorensen, Eric, Taplin, Francis, Trogani, Nancy, Versace, Richard, Walker, Heather, Weltchek-Engler, Susan, Wood, Alexander, Wu, Arthur, Atadja, Peter
Published in Journal of medicinal chemistry (09.10.2003)

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Second-Site NMR Screening with a Spin-Labeled First Ligand

Second-Site NMR Screening with a Spin-Labeled First Ligand

by Jahnke, Wolfgang, Perez, Lawrence B, Paris, C. Gregory, Strauss, André, Fendrich, Gabriele, Nalin, Carlo M
Published in Journal of the American Chemical Society (02.08.2000)

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Journal Article

Second-site NMR screening and linker design

Second-site NMR screening and linker design

by Jahnke, Wolfgang, Flörsheimer, Andreas, Blommers, Marcel J J, Paris, C Gregory, Heim, Jutta, Nalin, Carlo M, Perez, Lawrence B
Published in Current topics in medicinal chemistry (2003)

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Journal Article

The Synthesis of a Novel Inhibitor of B-Raf Kinase

The Synthesis of a Novel Inhibitor of B-Raf Kinase

by Denni-Dischert, Donatienne, Marterer, Wolfgang, Bänziger, Markus, Yusuff, Naeem, Batt, David, Ramsey, Tim, Geng, Peng, Michael, Walter, Wang, Run-Ming B, Taplin, Francis, Versace, Richard, Cesarz, David, Perez, Lawrence B
Published in Organic process research & development (01.01.2006)

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Journal Article

N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: Discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]-phen yl]-2-propenamide (NVP-LAQ824)

N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: Discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]-phen yl]-2-propenamide (NVP-LAQ824)

by REMISZEWSKI, Stacy W, SAMBUCETTI, Lidia C, DIAMANTIDIS, George, FRANCE, Dennis, GREEN, Michael A, HOWELL, Kobporn Lulu, KASHI, Rina, KWON, Paul, LASSOTA, Peter, MARTIN, Mary S, YIN MOU, PEREZ, Lawrence B, BAIR, Kenneth W, SHARMA, Sushil, SMITH, Troy, SORENSEN, Eric, TAPLIN, Francis, TROGANI, Nancy, VERSACE, Richard, WALKER, Heather, WELTCHEK-ENGLER, Susan, WOOD, Alexander, WU, Arthur, BONTEMPO, John, ATADJA, Peter, CESARZ, David, CHANDRAMOULI, Nagarajan, RU CHEN, MIN CHEUNG, CORNELL-KENNON, Susan, DEAN, Karl
Published in Journal of medicinal chemistry (2003)

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Journal Article

HYDROXAMATE DERIVATIVES USEFUL AS DEACETYLASE INHIBITORS

HYDROXAMATE DERIVATIVES USEFUL AS DEACETYLASE INHIBITORS

by BAIR KENNETH WALTER, SAMBUCETTI LIDIA, GREEN MICHAEL A, VERSACE RICHARD WILLIAM, PEREZ LAWRENCE B, REMISZEWSKI STACY W, SHARMA SUSHIL KUMAR
Year of Publication 31.05.2016

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Patent

n-hidróxi-3-[4-[[[2-(2-metil-1h-indol-3-il)etil]-amino]metil]fenil]-2e-2-propenamida, composição farmacêutica compreendendo o mesmo e uso

n-hidróxi-3-[4-[[[2-(2-metil-1h-indol-3-il)etil]-amino]metil]fenil]-2e-2-propenamida, composição farmacêutica compreendendo o mesmo e uso

by Michael A. Green, Lidia Sambucetti, Richard William Versace, Kenneth Walter Bair, Sushil Kumar Sharma, Lawrence B. Perez, Stacy W. Remiszewski
Year of Publication 25.05.2021

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Patent

COMPOSTOS E COMPOSIÇÕES COMO INIBIDORES DE QUINASES PROTEICAS

COMPOSTOS E COMPOSIÇÕES COMO INIBIDORES DE QUINASES PROTEICAS

by JON LOREN, LAWRENCE B. PEREZ, CLINTON BROOKS, LASZLO REVESZ, WOJCIECH WRONA, PAUL W. MANLEY, WERNER BREITENSTEIN, XIAOLIN LI, JULIET NABBAKA, VALENTINA MOLTENI, XIAODONG LIU, DONATELLA CHIANELLI
Year of Publication 26.11.2013

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Patent

Hydroxamate derivatives useful as deacetylase inhibitors and pharmaceutical compositions containing them

Hydroxamate derivatives useful as deacetylase inhibitors and pharmaceutical compositions containing them

by BAIR KENNETH WALTER MOUNTAIN LAKES, GREEN MICHAEL A. EASTON, PEREZ LAWRENCE B. HACKETTSTOWN, SHARMA SUSHIL KUMAR WEST ORANGE, VERSACE RICHARD WILLIAM WANAQUE, REMISZEWSKI STACY W. WASHINGTON TOWNSHIP, SAMBUCETTI LIDIA PACIFICA
Year of Publication 28.07.2014

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Patent

n-hidróxi-3-[4-[[[2-(2-metil-1h-indol-3-il)etil]-amino]metil]fenil]-2e-2-propenamida, composição farmacêutica compreendendo o mesmo e uso

n-hidróxi-3-[4-[[[2-(2-metil-1h-indol-3-il)etil]-amino]metil]fenil]-2e-2-propenamida, composição farmacêutica compreendendo o mesmo e uso

by Michael A. Green, Lidia Sambucetti, Richard William Versace, Kenneth Walter Bair, Sushil Kumar Sharma, Lawrence B. Perez, Stacy W. Remiszewski
Year of Publication 06.06.2017

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Patent

N-Hydroxylated amide derivatives and pharmaceutical compositions comprising thereof

N-Hydroxylated amide derivatives and pharmaceutical compositions comprising thereof

by BAIR KENNETH WALTER, SAMBUCETTI LIDIA, GREEN MICHAEL A, VERSACE RICHARD WILLIAM, PEREZ LAWRENCE B, REMISZEWSKI STACY W, SHARMA SUSHIL KUMAR
Year of Publication 05.04.2011

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Patent

HYDROXAMATE DERIVATIVES USEFUL AS DEACETYLASE INHIBITORS

HYDROXAMATE DERIVATIVES USEFUL AS DEACETYLASE INHIBITORS

by SHARMA, SUSHIL KUMAR, GREEN, MICHAEL A, SAMBUCETTI, LIDIA, BAIR, KENNETH WALTER, REMISZEWSKI, STACY W, PEREZ, LAWRENCE B, VERSACE, RICHARD WILLIAM
Year of Publication 08.03.2011

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Patent

Compounds and compositions as protein kinase inhibitors

Compounds and compositions as protein kinase inhibitors

by LOREN, JON, LI, XIAOLIN, LIU, XIAODONG, MANLEY, PAUL W, WRONA, WOJCIECH, BREITENSTEIN, WERNER, CHIANELLI, DONATELLA, PEREZ, LAWRENCE B, BROOKS, CLINTON, NABAKKA, JULIET, MOLTENI, VALENTINA, REVESZ, LASZLO
Year of Publication 20.10.2011

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Patent

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INIBITORS

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INIBITORS

by REVESZ,LASZLO, CHIANELLI,DONATELLA, BREITEINSTEI, LOREN,JON, MANLEY,PAUL W, LI,XIAOLIN, PEREZ,LAWRENCE B, BROOKS,CLINTON, MOLTENI,VALENTINA, WRONA,WOJCIECH, NABAKKA,JULIET, LIU,XIAODONG
Year of Publication 18.10.2010

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Patent

Deacetylase inhibitors

Deacetylase inhibitors

by GREEN, MICHA4EL A, SAMBUCETTI, LIDIA+, BAIR, KENNETH WALTER, REMISZEWSKI, STACY W, PEREZ, LAWRENCE B
Year of Publication 11.09.2007

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Patent

DEACETYLASE INHIBITORS

DEACETYLASE INHIBITORS

by MICHAEL A. GREEN, RICHARD WILLIAM VERSACE, SUSHIL KUMAR SHARMA, LAWRENCE B. PEREZ, LIDIA SAMBUCETTI, KENNETH WALTER BAIR, STACY W. REMISZEWSKI
Year of Publication 28.11.2008

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Patent

HYDROXAMATE DERIVATIVES USEFUL AS DEACETYLASE INHIBITORS

HYDROXAMATE DERIVATIVES USEFUL AS DEACETYLASE INHIBITORS

by BAIR KENNETH WALTER, SAMBUCETTI LIDIA, GREEN MICHAEL A, VERSACE RICHARD WILLIAM, PEREZ LAWRENCE B, REMISZEWSKI STACY W, SHARMA SUSHIL KUMAR
Year of Publication 31.08.2008

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Patent

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

by BROOKS CLINTON, LOREN JON, MANLEY PAUL WILLIAM, LIU XIAODONG, WRONA WOJCIECH, REVESZ LASZLO, PEREZ LAWRENCE B, CHIANELLI DONATELLA, NABAKKA JULIET, LI XIAOLIN, MOLTENI VALENTINA, BREITENSTEIN WERNER
Year of Publication 25.02.2010

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Patent