RNA N6‐methyladenosine methyltransferase‐like 3 promotes liver cancer progression through YTHDF2‐dependent posttranscriptional silencing of SOCS2
Chen, Mengnuo, Wei, Lai, Law, Cheuk‐Ting, Tsang, Felice Ho‐Ching, Shen, Jialing, Cheng, Carol Lai‐Hung, Tsang, Long‐Hin, Ho, Daniel Wai‐Hung, Chiu, David Kung‐Chun, Lee, Joyce Man‐Fong, Wong, Carmen Chak‐Lui, Ng, Irene Oi‐Lin, Wong, Chun‐Ming
Published in Hepatology (Baltimore, Md.) (01.06.2018)
Published in Hepatology (Baltimore, Md.) (01.06.2018)
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Journal Article
Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC
Wei, Lai, Lee, Derek, Law, Cheuk-Ting, Zhang, Misty Shuo, Shen, Jialing, Chin, Don Wai-Ching, Zhang, Allen, Tsang, Felice Ho-Ching, Wong, Ceci Lok-Sze, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui, Wong, Chun-Ming
Published in Nature communications (15.10.2019)
Published in Nature communications (15.10.2019)
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Journal Article
Histone methyltransferase G9a promotes liver cancer development by epigenetic silencing of tumor suppressor gene RARRES3
Wei, Lai, Chiu, David Kung-Chun, Tsang, Felice Ho-Ching, Law, Dicky Cheuk-Ting, Cheng, Carol Lai-Hung, Au, Sandy Leung-Kuen, Lee, Joyce Man-Fong, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin, Wong, Chun-Ming
Published in Journal of hepatology (01.10.2017)
Published in Journal of hepatology (01.10.2017)
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Journal Article
Aberrant Super‐Enhancer Landscape in Human Hepatocellular Carcinoma
Tsang, Felice Ho‐Ching, Law, Cheuk‐Ting, Tang, Tsz‐Ching Chloe, Cheng, Carol Lai‐Hung, Chin, Don Wai‐Ching, Tam, Wing‐Sum Vincy, Wei, Lai, Wong, Carmen Chak‐Lui, Ng, Irene Oi‐Lin, Wong, Chun‐Ming
Published in Hepatology (Baltimore, Md.) (01.06.2019)
Published in Hepatology (Baltimore, Md.) (01.06.2019)
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Journal Article
Up‐regulation of histone methyltransferase SETDB1 by multiple mechanisms in hepatocellular carcinoma promotes cancer metastasis
Wong, Chun‐Ming, Wei, Lai, Law, Cheuk‐Ting, Ho, Daniel Wai‐Hung, Tsang, Felice Ho‐Ching, Au, Sandy Leung‐Kuen, Sze, Karen Man‐Fong, Lee, Joyce Man‐Fong, Wong, Carmen Chak‐Lui, Ng, Irene Oi‐Lin
Published in Hepatology (Baltimore, Md.) (01.02.2016)
Published in Hepatology (Baltimore, Md.) (01.02.2016)
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Journal Article
HELLS Regulates Chromatin Remodeling and Epigenetic Silencing of Multiple Tumor Suppressor Genes in Human Hepatocellular Carcinoma
Law, Cheuk‐Ting, Wei, Lai, Tsang, Felice Ho‐Ching, Chan, Cerise Yuen‐Ki, Xu, Iris Ming‐Jing, Lai, Robin Kit‐Ho, Ho, Daniel Wai‐Hung, Lee, Joyce Man‐Fong, Wong, Carmen Chak‐Lui, Ng, Irene Oi‐Lin, Wong, Chun‐Ming
Published in Hepatology (Baltimore, Md.) (01.05.2019)
Published in Hepatology (Baltimore, Md.) (01.05.2019)
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Journal Article
Transketolase counteracts oxidative stress to drive cancer development
Xu, Iris Ming-Jing, Lai, Robin Kit-Ho, Lin, Shu-Hai, Tse, Aki Pui-Wah, Chiu, David Kung-Chun, Koh, Hui-Yu, Law, Cheuk-Ting, Wong, Chun-Ming, Cai, Zongwei, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2016)
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Journal Article
Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway
Kung-Chun Chiu, David, Pui-Wah Tse, Aki, Law, Cheuk-Ting, Ming-Jing Xu, Iris, Lee, Derek, Chen, Mengnuo, Kit-Ho Lai, Robin, Wai-Hin Yuen, Vincent, Wing-Sum Cheu, Jacinth, Wai-Hung Ho, Daniel, Wong, Chun-Ming, Zhang, Huafeng, Oi-Lin Ng, Irene, Chak-Lui Wong, Carmen
Published in Cell death & disease (09.12.2019)
Published in Cell death & disease (09.12.2019)
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Journal Article
Locus-specific expression of transposable elements in single cells with CELLO-seq
Berrens, Rebecca V, Yang, Andrian, Laumer, Christopher E, Lun, Aaron T L, Bieberich, Florian, Law, Cheuk-Ting, Lan, Guocheng, Imaz, Maria, Bowness, Joseph S, Brockdorff, Neil, Gaffney, Daniel J, Marioni, John C
Published in Nature biotechnology (01.04.2022)
Published in Nature biotechnology (01.04.2022)
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Journal Article
Histone chaperone FACT complex mediates oxidative stress response to promote liver cancer progression
Shen, Jialing, Chen, Mengnuo, Lee, Derek, Law, Cheuk-Ting, Wei, Lai, Tsang, Felice Ho-Ching, Chin, Don Wai-Ching, Cheng, Carol Lai-Hung, Lee, Joyce Man-Fong, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui, Wong, Chun-Ming
Published in Gut (01.02.2020)
Published in Gut (01.02.2020)
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Journal Article
Adaptive and Constitutive Activations of Malic Enzymes Confer Liver Cancer Multilayered Protection Against Reactive Oxygen Species
Lee, Derek, Zhang, Misty Shuo, Tsang, Felice Ho‐Ching, Bao, Macus Hao‐Ran, Xu, Iris Ming‐Jing, Lai, Robin Kit‐Ho, Chiu, David Kung‐Chun, Tse, Aki Pui‐Wah, Law, Cheuk‐Ting, Chan, Cerise Yuen‐Ki, Yuen, Vincent Wai‐Hin, Chui, Noreen Nog‐Qin, Ng, Irene Oi‐Lin, Wong, Chun‐Ming, Wong, Carmen Chak‐Lui
Published in Hepatology (Baltimore, Md.) (01.08.2021)
Published in Hepatology (Baltimore, Md.) (01.08.2021)
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Journal Article
NDUFA4L2 Fine-tunes Oxidative Stress in Hepatocellular Carcinoma
Lai, Robin Kit-Ho, Xu, Iris Ming-Jing, Chiu, David Kung-Chun, Tse, Aki Pui-Wah, Wei, Larry Lai, Law, Cheuk-Ting, Lee, Derek, Wong, Chun-Ming, Wong, Maria Pik, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Published in Clinical cancer research (15.06.2016)
Published in Clinical cancer research (15.06.2016)
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Journal Article
Polo-like kinase 4 inhibitor CFI-400945 suppresses liver cancer through cell cycle perturbation and eliciting antitumor immunity
Chan, Cerise Yuen-Ki, Yuen, Vincent Wai-Hin, Chiu, David Kung-Chun, Goh, Chi-Ching, Thu, Kelsie L, Cescon, David W, Soria-Bretones, Isabel, Law, Cheuk-Ting, Cheu, Jacinth Wing-Sum, Lee, Derek, Tse, Aki Pui-Wah, Tan, Kel Vin, Zhang, Misty Shuo, Wong, Bowie Po-Yee, Wong, Chun-Ming, Khong, Pek-Lan, Ng, Irene Oi-Lin, Bray, Mark R, Mak, Tak Wah, Yau, Thomas Chung-Cheung, Wong, Carmen Chak-Lui
Published in Hepatology (Baltimore, Md.) (01.03.2023)
Published in Hepatology (Baltimore, Md.) (01.03.2023)
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Journal Article
MiR-200b/200c/429 subfamily negatively regulates Rho/ROCK signaling pathway to suppress hepatocellular carcinoma metastasis
Wong, Chun-Ming, Wei, Lai, Au, Sandy Leung-Kuen, Fan, Dorothy Ngo-Yin, Zhou, Yuan, Tsang, Felice Ho-Ching, Law, Cheuk-Ting, Lee, Joyce Man-Fong, He, Xianghuo, Shi, Jue, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin
Published in Oncotarget (30.05.2015)
Published in Oncotarget (30.05.2015)
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Journal Article
Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma
Lee, Derek, Xu, Iris Ming-Jing, Chiu, David Kung-Chun, Lai, Robin Kit-Ho, Tse, Aki Pui-Wah, Lan Li, Lynna, Law, Cheuk-Ting, Tsang, Felice Ho-Ching, Wei, Larry Lai, Chan, Cerise Yuen-Ki, Wong, Chun-Ming, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Published in The Journal of clinical investigation (01.05.2017)
Published in The Journal of clinical investigation (01.05.2017)
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Journal Article
CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma
Chan, Cerise Yuen-Ki, Chiu, David Kung-Chun, Yuen, Vincent Wai-Hin, Law, Cheuk-Ting, Wong, Bowie Po-Yee, Thu, Kelsie Lynn, Cescon, David Ward, Soria-Bretones, Isabel, Cheu, Jacinth Wing-Sum, Lee, Derek, Tse, Aki Pui-Wah, Zhang, Misty Shuo, Tan, Kel Vin, Ng, Irene Oi-Lin, Khong, Pek-Lan, Yau, Thomas Chung-Cheung, Bray, Mark Robert, Mak, Tak Wah, Wong, Carmen Chak-Lui
Published in Proceedings of the National Academy of Sciences - PNAS (09.08.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (09.08.2022)
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Journal Article
Using mouse liver cancer models based on somatic genome editing to predict immune checkpoint inhibitor responses
Yuen, Vincent Wai-Hin, Chiu, David Kung-Chun, Law, Cheuk-Ting, Cheu, Jacinth Wing-Sum, Chan, Cerise Yuen-Ki, Wong, Bowie Po-Yee, Goh, Chi-Ching, Zhang, Misty Shuo, Xue, Helen Do-Gai, Tse, Aki Pui-Wah, Zhang, Yan, Lau, Henry Yee-Hin, Lee, Derek, Au-Yeung, Rex K.H., Wong, Chun-Ming, Wong, Carmen Chak-Lui
Published in Journal of hepatology (01.02.2023)
Published in Journal of hepatology (01.02.2023)
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Journal Article
Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer
Bao, Macus Hao-Ran, Yang, Chunxue, Tse, Aki Pui-Wah, Wei, Lai, Lee, Derek, Zhang, Misty Shuo, Goh, Chi Ching, Chiu, David Kung-Chun, Yuen, Vincent Wai-Hin, Law, Cheuk-Ting, Chin, Wai-Ching, Chui, Noreen Nog-Qin, Wong, Bowie Po-Yee, Chan, Cerise Yuen-Ki, Ng, Irene Oi-Lin, Chung, Clive Yik-Sham, Wong, Chun-Ming, Wong, Carmen Chak-Lui
Published in Cell reports (Cambridge) (26.01.2021)
Published in Cell reports (Cambridge) (26.01.2021)
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Journal Article
Histone chaperone FACT complex coordinates with HIF to mediate an expeditious transcription program to adapt to poorly oxygenated cancers
Shen, Jialing, Yang, Chunxue, Zhang, Misty Shuo, Chin, Don Wai-Ching, Chan, For-Fan, Law, Cheuk-Ting, Wang, Gengchao, Cheng, Carol Lai-Hung, Chen, Mengnuo, Wan, Rebecca Ting-Chi, Wu, Mengjie, Kuang, Zhijian, Sharma, Rakesh, Lee, Terence Kin Wah, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui, Wong, Chun-Ming
Published in Cell reports (Cambridge) (01.02.2022)
Published in Cell reports (Cambridge) (01.02.2022)
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Journal Article
In Vivo Genome-Wide CRISPR Activation Screening Identifies Functionally Important Long Noncoding RNAs in Hepatocellular Carcinoma
Wong, Lok-Sze, Wei, Lai, Wang, Gengchao, Law, Cheuk-Ting, Tsang, Felice Ho-Ching, Chin, Wai-Ching, Ng, Irene Oi-Lin, Wong, Chun-Ming
Published in Cellular and molecular gastroenterology and hepatology (01.01.2022)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2022)
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