SARS-CoV-2 Omicron variant is highly sensitive to molnupiravir, nirmatrelvir, and the combination
Li, Pengfei, Wang, Yining, Lavrijsen, Marla, Lamers, Mart M., de Vries, Annemarie C., Rottier, Robbert J., Bruno, Marco J., Peppelenbosch, Maikel P., Haagmans, Bart L., Pan, Qiuwei
Published in Cell research (01.03.2022)
Published in Cell research (01.03.2022)
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Journal Article
Commonly observed RNF43 mutations retain functionality in attenuating Wnt/β-catenin signaling and unlikely confer Wnt-dependency onto colorectal cancers
Li, Shan, Lavrijsen, Marla, Bakker, Aron, Magierowski, Marcin, Magierowska, Katarzyna, Liu, Pengyu, Wang, Wenhui, Peppelenbosch, Maikel P., Smits, Ron
Published in Oncogene (01.04.2020)
Published in Oncogene (01.04.2020)
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Journal Article
Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines
Wang, Wenhui, Liu, Pengyu, Lavrijsen, Marla, Li, Shan, Zhang, Ruyi, Li, Shanshan, van de Geer, Wesley S., van de Werken, Harmen J. G., Peppelenbosch, Maikel P., Smits, Ron
Published in Scientific reports (02.04.2021)
Published in Scientific reports (02.04.2021)
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Journal Article
Issues with RNF43 antibodies to reliably detect intracellular location
Li, Shanshan, Zhang, Ruyi, Lavrijsen, Marla, van den Bosch, Thierry P P, Peppelenbosch, Maikel P, Smits, Ron
Published in PloS one (06.04.2023)
Published in PloS one (06.04.2023)
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Journal Article
Differing pan-coronavirus antiviral potency of boceprevir and GC376 in vitro despite discordant molecular docking predictions
Wang, Yining, Li, Pengfei, Lavrijsen, Marla, Li, Yang, Ma, Zhongren, Peppelenbosch, Maikel P., Baig, Mirza S., Pan, Qiuwei
Published in Archives of virology (01.04.2022)
Published in Archives of virology (01.04.2022)
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Journal Article
Dissecting the effects and mechanism-of-action of statin use on fatty liver disease: a multidimensional study
Ayada, Ibrahim, van Kleef, Laurens, Zhang, Huai, Li, Pengfei, Liu, Kuan, Wang, Ling, Lavrijsen, Marla, Ghanbari, Mohsen, Van Der Laan, Luc J.W., Peppelenbosch, Maikel, Zheng, Ming-Hua, De Knegt, Robert, Pan, Qiuwei
Published in Journal of hepatology (01.07.2022)
Published in Journal of hepatology (01.07.2022)
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Journal Article
Shedding of klotho by ADAMs in the kidney
van Loon, Ellen P M, Pulskens, Wilco P, van der Hagen, Eline A E, Lavrijsen, Marla, Vervloet, Marc G, van Goor, Harry, Bindels, René J M, Hoenderop, Joost G J
Published in American journal of physiology. Renal physiology (15.08.2015)
Published in American journal of physiology. Renal physiology (15.08.2015)
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Journal Article
Recapitulating infection, thermal sensitivity and antiviral treatment of seasonal coronaviruses in human airway organoids
Li, Pengfei, Wang, Yining, Lamers, Mart M., Lavrijsen, Marla, Iriondo, Cinta, de Vries, Annemarie C., Rottier, Robbert J., Peppelenbosch, Maikel P., Haagmans, Bart L., Pan, Qiuwei
Published in EBioMedicine (01.07.2022)
Published in EBioMedicine (01.07.2022)
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Journal Article
Differentially Methylated Regions in Desmoid-Type Fibromatosis: A Comparison Between CTNNB1 S45F and T41A Tumors
Timbergen, Milea J M, Boers, Ruben, Vriends, Anne L M, Boers, Joachim, van IJcken, Wilfred F J, Lavrijsen, Marla, Grünhagen, Dirk J, Verhoef, Cornelis, Sleijfer, Stefan, Smits, Ron, Gribnau, Joost, Wiemer, Erik A C
Published in Frontiers in oncology (29.10.2020)
Published in Frontiers in oncology (29.10.2020)
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Journal Article
Individual variations in maternal care early in life correlate with later life decision-making and c-fos expression in prefrontal subregions of rats
van Hasselt, Felisa N, de Visser, Leonie, Tieskens, Jacintha M, Cornelisse, Sandra, Baars, Annemarie M, Lavrijsen, Marla, Krugers, Harm J, van den Bos, Ruud, Joëls, Marian
Published in PloS one (31.05.2012)
Published in PloS one (31.05.2012)
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Journal Article
Nirmatrelvir exerts distinct antiviral potency against different human coronaviruses
Li, Jiajing, Wang, Yining, Solanki, Kundan, Atre, Rajat, Lavrijsen, Marla, Pan, Qiuwei, Baig, Mirza S., Li, Pengfei
Published in Antiviral research (01.03.2023)
Published in Antiviral research (01.03.2023)
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Journal Article
Commonly observed RNF43 mutations retain functionality in attenuating Wnt/[beta]-catenin signaling and unlikely confer Wnt-dependency onto colorectal cancers
Li, Shan, Lavrijsen, Marla, Bakker, Aron, Magierowski, Marcin, Magierowska, Katarzyna, Liu, Pengyu, Wang, Wenhui
Published in Oncogene (23.04.2020)
Published in Oncogene (23.04.2020)
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Journal Article
Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling
Zhang, Ruyi, Li, Shanshan, Schippers, Kelly, Li, Yunlong, Eimers, Boaz, Lavrijsen, Marla, Wang, Ling, Cui, Guofei, Chen, Xin, Peppelenbosch, Maikel P, Lebbink, Joyce H G, Smits, Ron
Published in Cancer research (Chicago, Ill.) (02.05.2024)
Published in Cancer research (Chicago, Ill.) (02.05.2024)
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Journal Article
Oncogenic Mutations in Armadillo Repeats 5 and 6 of β-Catenin Reduce Binding to APC, Increasing Signaling and Transcription of Target Genes
Liu, Pengyu, Liang, Binyong, Liu, Menggang, Lebbink, Joyce H.G., Li, Shan, Qian, Manning, Lavrijsen, Marla, Peppelenbosch, Maikel P., Chen, Xin, Smits, Ron
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2020)
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2020)
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Journal Article
Investigating theobromine as a potential anti-human coronaviral agent
Li, Jiajing, Wang, Yining, Rajpoot, Sajjan, Lavrijsen, Marla, Pan, Qiuwei, Li, Pengfei, Baig, Mirza S
Published in Microbiology and immunology (01.09.2023)
Published in Microbiology and immunology (01.09.2023)
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Journal Article
Repurposing dyphylline as a pan-coronavirus antiviral therapy
Wang, Yining, Rajpoot, Sajjan, Li, Pengfei, Lavrijsen, Marla, Ma, Zhongren, Hirani, Nik, Saqib, Uzma, Pan, Qiuwei, Baig, Mirza S
Published in Future medicinal chemistry (01.05.2022)
Published in Future medicinal chemistry (01.05.2022)
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Journal Article
Dissecting the multifaceted impact of statin use on fatty liver disease: a multidimensional study
Ayada, Ibrahim, van Kleef, Laurens A., Zhang, Huai, Liu, Kuan, Li, Pengfei, Abozaid, Yasir J., Lavrijsen, Marla, Janssen, Harry L.A., van der Laan, Luc J.W., Ghanbari, Mohsen, Peppelenbosch, Maikel P., Zheng, Ming-Hua, de Knegt, Robert J., Pan, Qiuwei
Published in EBioMedicine (01.01.2023)
Published in EBioMedicine (01.01.2023)
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Journal Article
Recapitulating hepatitis E virus-host interactions and facilitating antiviral drug discovery in human liver-derived organoids
Li, Pengfei, Li, Yunlong, Wang, Yijin, Liu, Jiaye, Lavrijsen, Marla, Li, Yang, Zhang, Ruyi, Verstegen, Monique M A, Wang, Yining, Li, Tian-Cheng, Ma, Zhongren, Kainov, Denis E, Bruno, Marco J, de Man, Robert A, van der Laan, Luc J W, Peppelenbosch, Maikel P, Pan, Qiuwei
Published in Science advances (21.01.2022)
Published in Science advances (21.01.2022)
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