Detection and isolation of H5N1 influenza virus from large volumes of natural water
Khalenkov, Alexey, Laver, W. Graeme, Webster, Robert G.
Published in Journal of virological methods (01.04.2008)
Published in Journal of virological methods (01.04.2008)
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Journal Article
BCX-1812 (RWJ-270201): Discovery of a Novel, Highly Potent, Orally Active, and Selective Influenza Neuraminidase Inhibitor through Structure-Based Drug Design
Babu, Y. Sudhakar, Chand, Pooran, Bantia, Shanta, Kotian, Pravin, Dehghani, Ali, El-Kattan, Yahya, Lin, Tsu-Hsing, Hutchison, Tracy L, Elliott, Arthur J, Parker, Cynthia D, Ananth, Sandya L, Horn, LaShun L, Laver, Graeme W, Montgomery, John A
Published in Journal of medicinal chemistry (21.09.2000)
Published in Journal of medicinal chemistry (21.09.2000)
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Journal Article
Antibody Epitopes on the Neuraminidase of a Recent H3N2 Influenza Virus (A/Memphis/31/98)
Gulati, Upma, Hwang, Chi-Ching, Venkatramani, Lalitha, Gulati, Shelly, Stray, Stephen J, Lee, Janis T, Laver, W Graeme, Bochkarev, Alexey, Zlotnick, Adam, Air, Gillian M
Published in Journal of Virology (01.12.2002)
Published in Journal of Virology (01.12.2002)
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Journal Article
An Epidemiologically Significant Epitope of a 1998 Human Influenza Virus Neuraminidase Forms a Highly Hydrated Interface in the NA–Antibody Complex
Venkatramani, Lalitha, Bochkareva, Elena, Lee, Janis T., Gulati, Upma, Graeme Laver, W., Bochkarev, Alexey, Air, Gillian M.
Published in Journal of molecular biology (24.02.2006)
Published in Journal of molecular biology (24.02.2006)
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Journal Article
Structure−Activity Relationship Studies of Novel Carbocyclic Influenza Neuraminidase Inhibitors
Kim, Choung U, Lew, Willard, Williams, Matthew A, Wu, Huiwei, Zhang, Lijun, Chen, Xiaowu, Escarpe, Paul A, Mendel, Dirk B, Laver, W. Graeme, Stevens, Raymond C
Published in Journal of medicinal chemistry (02.07.1998)
Published in Journal of medicinal chemistry (02.07.1998)
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Journal Article
Design, Synthesis, and Structural Analysis of Influenza Neuraminidase Inhibitors Containing Pyrrolidine Cores
Wang, Gary T, Chen, Yuanwei, Wang, Sheldon, Gentles, Robert, Sowin, Thomas, Kati, Warren, Muchmore, Steve, Giranda, Vincent, Stewart, Kent, Sham, Hing, Kempf, Dale, Laver, W. Graeme
Published in Journal of medicinal chemistry (12.04.2001)
Published in Journal of medicinal chemistry (12.04.2001)
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Journal Article
Structure-Based Characterization and Optimization of Novel Hydrophobic Binding Interactions in a Series of Pyrrolidine Influenza Neuraminidase Inhibitors
Maring, Clarence J, Stoll, Vincent S, Zhao, Chen, Sun, Minghua, Krueger, Allan C, Stewart, Kent D, Madigan, Darold L, Kati, Warren M, Xu, Yibo, Carrick, Robert J, Montgomery, Debra A, Kempf-Grote, Anita, Marsh, Kennan C, Molla, Akhteruzzaman, Steffy, Kevin R, Sham, Hing L, Laver, W. Graeme, Gu, Yu-gui, Kempf, Dale J, Kohlbrenner, William E
Published in Journal of medicinal chemistry (16.06.2005)
Published in Journal of medicinal chemistry (16.06.2005)
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Journal Article
Approaches and Strategies for the Treatment of Influenza Virus Infections
Colacino, Joseph M, Staschke, Kirk A, Laver, W Graeme
Published in Antiviral Chemistry and Chemotherapy (01.07.1999)
Published in Antiviral Chemistry and Chemotherapy (01.07.1999)
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Book Review
Journal Article
Epitopes on protein antigens: Misconceptions and realities
Laver, W.Graeme, Air, Gillian M., Webster, Robert G., Smith-Gill, Sandra J.
Published in Cell (18.05.1990)
Published in Cell (18.05.1990)
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Book Review
Journal Article
Crystal Structure of a Bacterial Sialidase (From Salmonella typhimurium LT2) Shows the Same Fold as an Influenza Virus Neuraminidase
Crennell, Susan J., Garman, Elspeth F., Laver, W. Graeme, Vimr, Eric R., Taylor, Garry L.
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.1993)
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Journal Article
Conference Proceeding
Novel α- and β-Amino Acid Inhibitors of Influenza Virus Neuraminidase
KATI, Warren M, MONTGOMERY, Debra, MARING, Clarence, STOLL, Vincent S, GIRANDA, Vincent, XIAOQI CHEN, LAVER, W. Graeme, KOHLBRENNER, William, NORBECK, Daniel W
Published in Antimicrobial Agents and Chemotherapy (01.09.2001)
Published in Antimicrobial Agents and Chemotherapy (01.09.2001)
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Journal Article
Potent Inhibition of Influenza Sialidase by a Benzoic Acid Containing a 2-Pyrrolidinone Substituent
Atigadda, Venkatram R, Brouillette, Wayne J, Duarte, Franco, Ali, Shoukath M, Babu, Yarlagadda S, Bantia, Shanta, Chand, Pooran, Chu, Naiming, Montgomery, John A, Walsh, David A, Sudbeck, Elise A, Finley, James, Luo, Ming, Air, Gillian M, Laver, Graeme W
Published in Journal of medicinal chemistry (01.07.1999)
Published in Journal of medicinal chemistry (01.07.1999)
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Journal Article
Design, synthesis, and neuraminidase inhibitory activity of GS-4071 analogues that utilize a novel hydrophobic paradigm
Hanessian, Stephen, Wang, Jianchio, Montgomery, Debra, Stoll, Vincent, Stewart, Kent D., Kati, Warren, Maring, Clarence, Kempf, Dale, Hutchins, Charles, Laver, W.Graeme
Published in Bioorganic & medicinal chemistry letters (02.12.2002)
Published in Bioorganic & medicinal chemistry letters (02.12.2002)
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Journal Article
Design and Synthesis of Benzoic Acid Derivatives as Influenza Neuraminidase Inhibitors Using Structure-Based Drug Design
Chand, Pooran, Babu, Yarlagadda S, Bantia, Shanta, Chu, Naiming, Cole, L. Brent, Kotian, Pravin L, Laver, W. Graeme, Montgomery, John A, Pathak, Ved P, Petty, Sandra L, Shrout, David P, Walsh, David A, Walsh, Gerald M
Published in Journal of medicinal chemistry (05.12.1997)
Published in Journal of medicinal chemistry (05.12.1997)
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Journal Article
Structures of Aromatic Inhibitors of Influenza Virus Neuraminidase
Jedrzejas, Marek J, Singh, Sangeeta, Brouillette, Wayne J, Laver, W. Graeme, Air, Gillian M, Luo, Ming
Published in Biochemistry (Easton) (01.03.1995)
Published in Biochemistry (Easton) (01.03.1995)
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Journal Article
Hydrophobic benzoic acids as inhibitors of influenza neuraminidase
Atigadda, Venkatram R., Brouillette, Wayne J., Duarte, Franco, Babu, Yarlagadda S., Bantia, Shanta, Chand, Pooran, Chu, Naiming, Montgomery, John A., Walsh, David A., Sudbeck, Elise, Finley, James, Air, Gillian M., Luo, Ming, Laver, Graeme W.
Published in Bioorganic & medicinal chemistry (01.11.1999)
Published in Bioorganic & medicinal chemistry (01.11.1999)
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Journal Article
Selection of Influenza A and B Viruses for Resistance to 4-Guanidino-Neu5Ac2en in Cell Culture
Colacino, Joseph M., Laver, W. Graeme, Air, Gillian M.
Published in The Journal of infectious diseases (01.08.1997)
Published in The Journal of infectious diseases (01.08.1997)
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Journal Article
Conference Proceeding
Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site: Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza Activity
Kim, Choung U, Lew, Willard, Williams, Matthew A, Liu, Hongtao, Zhang, Lijun, Swaminathan, S, Bischofberger, Norbert, Chen, Ming S, Mendel, Dirk B, Tai, Chun Y, Laver, W. Graeme, Stevens, Raymond C
Published in Journal of the American Chemical Society (29.01.1997)
Published in Journal of the American Chemical Society (29.01.1997)
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Journal Article