Fas/CD95-Induced Chemokines Can Serve as “Find-Me” Signals for Apoptotic Cells
Cullen, Sean P., Henry, Conor M., Kearney, Conor J., Logue, Susan E., Feoktistova, Maria, Tynan, Graham A., Lavelle, Ed C., Leverkus, Martin, Martin, Seamus J.
Published in Molecular cell (28.03.2013)
Published in Molecular cell (28.03.2013)
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The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons
Carroll, Elizabeth. C., Jin, Lei, Mori, Andres, Muñoz-Wolf, Natalia, Oleszycka, Ewa, Moran, Hannah B.T., Mansouri, Samira, McEntee, Craig P., Lambe, Eimear, Agger, Else Marie, Andersen, Peter, Cunningham, Colm, Hertzog, Paul, Fitzgerald, Katherine A., Bowie, Andrew G., Lavelle, Ed C.
Published in Immunity (Cambridge, Mass.) (15.03.2016)
Published in Immunity (Cambridge, Mass.) (15.03.2016)
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Relative contribution of Th1 and Th17 cells in adaptive immunity to Bordetella pertussis: towards the rational design of an improved acellular pertussis vaccine
Ross, Pádraig J, Sutton, Caroline E, Higgins, Sarah, Allen, Aideen C, Walsh, Kevin, Misiak, Alicja, Lavelle, Ed C, McLoughlin, Rachel M, Mills, Kingston H G
Published in PLoS pathogens (01.04.2013)
Published in PLoS pathogens (01.04.2013)
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Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing
Clancy, Danielle M., Sullivan, Graeme P., Moran, Hannah B.T., Henry, Conor M., Reeves, Emer P., McElvaney, Noel G., Lavelle, Ed C., Martin, Seamus J.
Published in Cell reports (Cambridge) (13.03.2018)
Published in Cell reports (Cambridge) (13.03.2018)
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Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α
Afonina, Inna S., Tynan, Graham A., Logue, Susan E., Cullen, Sean P., Bots, Michael, Lüthi, Alexander U., Reeves, Emer P., McElvaney, Noel G., Medema, Jan P., Lavelle, Ed C., Martin, Seamus J.
Published in Molecular cell (21.10.2011)
Published in Molecular cell (21.10.2011)
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NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components
Doyle, Sarah L, Campbell, Matthew, Ozaki, Ema, Salomon, Robert G, Mori, Andres, Kenna, Paul F, Farrar, Gwyneth Jane, Kiang, Anna-Sophia, Humphries, Marian M, Lavelle, Ed C, O'Neill, Luke A J, Hollyfield, Joe G, Humphries, Peter
Published in Nature medicine (01.05.2012)
Published in Nature medicine (01.05.2012)
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Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4
McNeela, Edel A, Burke, Aine, Neill, Daniel R, Baxter, Cathy, Fernandes, Vitor E, Ferreira, Daniela, Smeaton, Sarah, El-Rachkidy, Rana, McLoughlin, Rachel M, Mori, Andres, Moran, Barry, Fitzgerald, Katherine A, Tschopp, Jurg, Pétrilli, Virginie, Andrew, Peter W, Kadioglu, Aras, Lavelle, Ed C
Published in PLoS pathogens (11.11.2010)
Published in PLoS pathogens (11.11.2010)
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Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21
Hackett, Emer E., Charles-Messance, Hugo, O’Leary, Seónadh M., Gleeson, Laura E., Muñoz-Wolf, Natalia, Case, Sarah, Wedderburn, Anna, Johnston, Daniel G.W., Williams, Michelle A., Smyth, Alicia, Ouimet, Mireille, Moore, Kathryn J., Lavelle, Ed C., Corr, Sinéad C., Gordon, Stephen V., Keane, Joseph, Sheedy, Frederick J.
Published in Cell reports (Cambridge) (07.01.2020)
Published in Cell reports (Cambridge) (07.01.2020)
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Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression
Nazmi, Arshed, Field, Robert H., Griffin, Eadaoin W., Haugh, Orla, Hennessy, Edel, Cox, Donal, Reis, Renata, Tortorelli, Lucas, Murray, Carol L., Lopez‐Rodriguez, Ana Belen, Jin, Lei, Lavelle, Ed C., Dunne, Aisling, Cunningham, Colm
Published in Glia (01.07.2019)
Published in Glia (01.07.2019)
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Advances in immunotherapy for the treatment of glioblastoma
Tivnan, Amanda, Heilinger, Tatjana, Lavelle, Ed C., Prehn, Jochen H. M.
Published in Journal of Neuro - Oncology (01.01.2017)
Published in Journal of Neuro - Oncology (01.01.2017)
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Book Review
Mechanistic study of the adjuvant effect of chitosan-aluminum nanoparticles
Lebre, F., Pedroso de Lima, M.C., Lavelle, Ed C., Borges, O.
Published in International journal of pharmaceutics (01.12.2018)
Published in International journal of pharmaceutics (01.12.2018)
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Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases
Lüthi, Alexander U., Cullen, Sean P., McNeela, Edel A., Duriez, Patrick J., Afonina, Inna S., Sheridan, Clare, Brumatti, Gabriela, Taylor, Rebecca C., Kersse, Kristof, Vandenabeele, Peter, Lavelle, Ed C., Martin, Seamus J.
Published in Immunity (Cambridge, Mass.) (17.07.2009)
Published in Immunity (Cambridge, Mass.) (17.07.2009)
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Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
Sharp, Fiona A, Ruane, Darren, Claass, Benjamin, Creagh, Emma, Harris, James, Malyala, Padma, Singh, Manomohan, O'Hagan, Derek T, Pétrilli, Virginie, Tschopp, Jurg, O'Neill, Luke A.J, Lavelle, Ed C
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2009)
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Functionalization of Carbon Nanoparticles Modulates Inflammatory Cell Recruitment and NLRP3 Inflammasome Activation
Yang, Marie, Flavin, Kevin, Kopf, Ilona, Radics, Gabor, Hearnden, Claire H. A., McManus, Gavin J., Moran, Barry, Villalta-Cerdas, Adrian, Echegoyen, Luis A., Giordani, Silvia, Lavelle, Ed C.
Published in Small (Weinheim an der Bergstrasse, Germany) (20.12.2013)
Published in Small (Weinheim an der Bergstrasse, Germany) (20.12.2013)
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