PICALM modulates autophagy activity and tau accumulation
Moreau, Kevin, Fleming, Angeleen, Imarisio, Sara, Lopez Ramirez, Ana, Mercer, Jacob L., Jimenez-Sanchez, Maria, Bento, Carla F., Puri, Claudia, Zavodszky, Eszter, Siddiqi, Farah, Lavau, Catherine P., Betton, Maureen, O’Kane, Cahir J., Wechsler, Daniel S., Rubinsztein, David C.
Published in Nature communications (22.09.2014)
Published in Nature communications (22.09.2014)
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Journal Article
Iron deprivation in cancer--potential therapeutic implications
Heath, Jessica L, Weiss, Joshua M, Lavau, Catherine P, Wechsler, Daniel S
Published in Nutrients (24.07.2013)
Published in Nutrients (24.07.2013)
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Book Review
The SQSTM1-NUP214 fusion protein interacts with Crm1, activates Hoxa and Meis1 genes, and drives leukemogenesis in mice
Lavau, Catherine P, Aumann, Waitman K, Sze, Sei-Gyung K, Gupta, Veerain, Ripple, Katelyn, Port, Sarah A, Kehlenbach, Ralph H, Wechsler, Daniel S
Published in PloS one (28.04.2020)
Published in PloS one (28.04.2020)
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Journal Article
Fusion of the CRM1 nuclear export receptor to AF10 causes leukemia and transcriptional activation of HOXA genes
Aumann, Waitman K., Heath, Jessica L., Conway, Amanda E., Sze, Sei-Gyung Kim, Gupta, Veerain K., Kazi, Rafi R., Tope, Donald R., Wechsler, Daniel S., Lavau, Catherine P.
Published in Leukemia (01.03.2021)
Published in Leukemia (01.03.2021)
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Journal Article
The PICALM protein plays a key role in iron homeostasis and cell proliferation
Scotland, Paula B, Heath, Jessica L, Conway, Amanda E, Porter, Natasha B, Armstrong, Michael B, Walker, Jennifer A, Klebig, Mitchell L, Lavau, Catherine P, Wechsler, Daniel S
Published in PloS one (30.08.2012)
Published in PloS one (30.08.2012)
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Journal Article
A CALM-derived nuclear export signal is essential for CALM-AF10–mediated leukemogenesis
Conway, Amanda E., Scotland, Paula B., Lavau, Catherine P., Wechsler, Daniel S.
Published in Blood (06.06.2013)
Published in Blood (06.06.2013)
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Journal Article
Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis
Mercer, Jacob L, Argus, Joseph P, Crabtree, Donna M, Keenan, Melissa M, Wilks, Moses Q, Chi, Jen-Tsan Ashley, Bensinger, Steven J, Lavau, Catherine P, Wechsler, Daniel S
Published in PloS one (15.06.2015)
Published in PloS one (15.06.2015)
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Journal Article
Abl family kinases modulate T cell-mediated inflammation and chemokine-induced migration through the adaptor HEF1 and the GTPase Rap1
Gu, Jing Jin, Lavau, Catherine P, Pugacheva, Elena, Soderblom, Erik J, Moseley, M Arthur, Pendergast, Ann Marie
Published in Science signaling (17.07.2012)
Published in Science signaling (17.07.2012)
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Journal Article
Effects of iron depletion on CALM-AF10 leukemias
Heath, Jessica L, Weiss, Joshua M, Lavau, Catherine P, Wechsler, Daniel S
Published in Experimental hematology (01.12.2014)
Published in Experimental hematology (01.12.2014)
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Journal Article
Corrigendum: PICALM modulates autophagy activity and tau accumulation
Moreau, Kevin, Fleming, Angeleen, Imarisio, Sara, Lopez Ramirez, Ana, Mercer, Jacob L, Jimenez-sanchez, Maria, Bento, Carla F, Puri, Claudia, Zavodszky, Eszter, Siddiqi, Farah, Lavau, Catherine P, Betton, Maureen, O'kane, Cahir J, Wechsler, Daniel S, Rubinsztein, David C
Published in Nature communications (28.01.2015)
Published in Nature communications (28.01.2015)
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Journal Article
A SIX1/EYA2 Inhibitor Impairs CALM-AF10 and Jurkat Leukemia Cell Proliferation
Aumann, Waitman Kurt, Lavau, Catherine P., Chen, Dongdong Julie, Conway, Amanda E., Ford, Heide, Wechsler, Daniel S.
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
SIX1 Is a Novel Effector Gene in CALM-AF10 Leukemia
Aumann, Waitman K., Lavau, Catherine P., Harrington, Amanda, Conway, Amanda E., Wechsler, Daniel S.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
The SIX1 homeobox Gene Is a Novel Therapeutic Target in CALM-AF10 Leukemogenesis
Aumann, Waitman K., Lavau, Catherine P., Harrington, Amanda, Tope, Donald, Conway, Amanda E., Zhou, Hengbo, Ford, Heide, Wechsler, Daniel S.
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
The SQSTM1-NUP214 Fusion Protein Cooperates with Crm1 to Activate Hoxa Genes and Drives Leukemogenesis in Mice
Aumann, Waitman K., Sze, Sei-Gyung K., Gupta, Veerain, Ripple, Katelyn, Port, Sarah, Kehlenbach, Ralph, Wechsler, Daniel S., Lavau, Catherine P.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
The CRM1 Nuclear Export Receptor Activates HOXA Gene Expression in Leukemogenesis
Lavau, Catherine P, Heath, Jessica L, Lee, William H, Conway, Amanda E, Wechsler, Daniel S
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Iron Deprivation Impairs Proliferation of CALM-AF10 leukemia Cells in Vitro and in Vivo
Heath, Jessica L, Weiss, Joshua, Scotland, Paula B., Lavau, Catherine P., Wechsler, Daniel S.
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
Abstract LB-154: Nuclear export of CALM-AF10 is essential for leukemogenesis
Conway, Amanda E., Scotland, Paula B., Lavau, Catherine P., Wechsler, Daniel S.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
CALM Insufficiency Impairs Leukemia Cell Proliferation by Limiting Iron Uptake
Lavau, Catherine P., Heath, Jessica L, Scotland, Paula B., Wechsler, Daniel S.
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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