Eliapixant is a selective P2X3 receptor antagonist for the treatment of disorders associated with hypersensitive nerve fibers
Davenport, Adam J, Neagoe, Ioana, Bräuer, Nico, Koch, Markus, Rotgeri, Andrea, Nagel, Jens, Laux-Biehlmann, Alexis, Machet, Frederic, Coelho, Anne-Marie, Boyce, Susan, Carty, Nikisha, Gemkow, Mark J, Hess, Stephen D, Zollner, Thomas M, Fischer, Oliver M
Published in Scientific reports (06.10.2021)
Published in Scientific reports (06.10.2021)
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Journal Article
Stable isotope‐labelled morphine to study in vivo central and peripheral morphine glucuronidation and brain transport in tolerant mice
Weinsanto, Ivan, Laux‐Biehlmann, Alexis, Mouheiche, Jinane, Maduna, Tando, Delalande, François, Chavant, Virginie, Gabel, Florian, Darbon, Pascal, Charlet, Alexandre, Poisbeau, Pierrick, Lamshöft, Marc, Van Dorsselaer, Alain, Cianferani, Sarah, Parat, Marie‐Odile, Goumon, Yannick
Published in British journal of pharmacology (01.10.2018)
Published in British journal of pharmacology (01.10.2018)
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Journal Article
Menstruation pulls the trigger for inflammation and pain in endometriosis
Laux-Biehlmann, Alexis, d’Hooghe, Thomas, Zollner, Thomas M
Published in Trends in pharmacological sciences (Regular ed.) (01.05.2015)
Published in Trends in pharmacological sciences (Regular ed.) (01.05.2015)
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Journal Article
Discovery and Characterization of the Potent and Selective P2X4 Inhibitor N‑[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile
Werner, Stefan, Mesch, Stefanie, Hillig, Roman C, ter Laak, Antonius, Klint, Julie, Neagoe, Ioana, Laux-Biehlmann, Alexis, Dahllöf, Henrik, Bräuer, Nico, Puetter, Vera, Nubbemeyer, Reinhard, Schulz, Simone, Bairlein, Michaela, Zollner, Thomas M, Steinmeyer, Andreas
Published in Journal of medicinal chemistry (26.12.2019)
Published in Journal of medicinal chemistry (26.12.2019)
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Journal Article
Anxiety-related behaviors without observation of generalized pain in a mouse model of endometriosis
Nunez-Badinez, Paulina, Laux-Biehlmann, Alexis, Hayward, Michael D, Buiakova, Olesia, Zollner, Thomas M, Nagel, Jens
Published in Frontiers in behavioral neuroscience (09.02.2023)
Published in Frontiers in behavioral neuroscience (09.02.2023)
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Journal Article
Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions
Thézénas, Marie-Laëtitia, De Leo, Bianca, Laux-Biehlmann, Alexis, Bafligil, Cemsel, Elger, Bernd, Tapmeier, Thomas, Morten, Karl, Rahmioglu, Nilufer, Dakin, Stephanie G, Charles, Philip, Martinez, Fernando Estrada, Steers, Graham, Fischer, Oliver M, Mueller, Joerg, Hess-Stumpp, Holger, Steinmeyer, Andreas, Manek, Sanjiv, Zondervan, Krina T, Kennedy, Stephen, Becker, Christian M, Shang, Catherine, Zollner, Thomas M, Kessler, Benedikt M, Oppermann, Udo
Published in Scientific reports (30.01.2020)
Published in Scientific reports (30.01.2020)
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Journal Article
Author Correction: Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions
Thézénas, Marie-Laëtitia, De Leo, Bianca, Laux-Biehlmann, Alexis, Bafligil, Cemsel, Elger, Bernd, Tapmeier, Thomas, Morten, Karl, Rahmioglu, Nilufer, Dakin, Stephanie G, Charles, Philip, Martinez, Fernando Estrada, Steers, Graham, Fischer, Oliver M, Mueller, Joerg, Hess-Stumpp, Holger, Steinmeyer, Andreas, Manek, Sanjiv, Zondervan, Krina T, Kennedy, Stephen, Becker, Christian M, Shang, Catherine, Zollner, Thomas M, Kessler, Benedikt M, Oppermann, Udo
Published in Scientific reports (24.03.2020)
Published in Scientific reports (24.03.2020)
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Journal Article
Lithium reverses mechanical allodynia through a mu opioid-dependent mechanism
Weinsanto, Ivan, Mouheiche, Jinane, Laux-Biehlmann, Alexis, Aouad, Maya, Maduna, Tando, Petit-Demoulière, Nathalie, Chavant, Virginie, Poisbeau, Pierrick, Darbon, Pascal, Charlet, Alexandre, Giersch, Anne, Parat, Marie-Odile, Goumon, Yannick
Published in Molecular pain (01.01.2018)
Published in Molecular pain (01.01.2018)
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Journal Article
Morphine Binds Creatine Kinase B and Inhibits Its Activity
Weinsanto, Ivan, Mouheiche, Jinane, Laux-Biehlmann, Alexis, Delalande, François, Marquette, Arnaud, Chavant, Virginie, Gabel, Florian, Cianferani, Sarah, Charlet, Alexandre, Parat, Marie-Odile, Goumon, Yannick
Published in Frontiers in cellular neuroscience (03.12.2018)
Published in Frontiers in cellular neuroscience (03.12.2018)
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Journal Article
Corrigendum: Morphine Binds Creatine Kinase B and Inhibits Its Activity
Weinsanto, Ivan, Mouheiche, Jinane, Laux-Biehlmann, Alexis, Delalande, François, Marquette, Arnaud, Chavant, Virginie, Gabel, Florian, Cianferani, Sarah, Charlet, Alexandre, Parat, Marie-Odile, Goumon, Yannick
Published in Frontiers in cellular neuroscience (02.07.2019)
Published in Frontiers in cellular neuroscience (02.07.2019)
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Journal Article
Comparison of serum and lithium‐heparinate plasma for the accurate measurements of endogenous and exogenous morphine concentrations
Laux‐Biehlmann, Alexis, Gräfe, Nadja, Mouheiche, Jinane, Stuber, Denise, Welters, Ingeborg D., Delalande, François, Poisbeau, Pierrick, Garnero, Patrick, Metz‐Boutigue, Marie‐Hélène, Schneider, Francis, Goumon, Yannick
Published in British journal of clinical pharmacology (01.08.2012)
Published in British journal of clinical pharmacology (01.08.2012)
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Journal Article
Endogenous morphine-6-glucuronide (M6G) is present in the plasma of patients: Validation of a specific anti-M6G antibody for clinical and basic research
Laux-Biehlmann, Alexis, Chung, Hélène, Mouheiche, Jinane, Vérièpe, Julie, Delalande, François, Lamshöft, Marc, Welters, Ingeborg D., Soldevila, Stéphanie, Bazin, Hervé, Lamarque, Laurent, Dorsselaer, Alain Van, Poisbeau, Pierrick, Schneider, Francis, Goumon, Yannick, Garnero, Patrick
Published in BioFactors (Oxford) (01.01.2014)
Published in BioFactors (Oxford) (01.01.2014)
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Journal Article
P2X4 수용체 길항 활성을 갖는 치환된 N-페닐아세트아미드
SCOTT ROBERT JOHN, BAEURLE STEFAN, RING SVEN, WALTER DARYL SIMON, LAUX BIEHLMANN ALEXIS, WITTROCK SVEN, NAGEL JENS, POOK ELISABETH, NUBBEMEYER REINHARD
Year of Publication 07.03.2023
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Year of Publication 07.03.2023
Patent
Discovery of BAY-390, a Selective CNS Penetrant Chemical Probe as Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonist
Mesch, Stefanie, Walter, Daryl, Laux-Biehlmann, Alexis, Basting, Daniel, Flanagan, Stuart, Miyatake Ondozabal, Hideki, Bäurle, Stefan, Pearson, Christopher, Jenkins, James, Elves, Philip, Hess, Stephen, Coelho, Anne-Marie, Rotgeri, Andrea, Bothe, Ulrich, Nawaz, Schanila, Zollner, Thomas M., Steinmeyer, Andreas
Published in Journal of medicinal chemistry (26.01.2023)
Published in Journal of medicinal chemistry (26.01.2023)
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Journal Article
Discovery and In Vitro Characterization of BAY 2686013, an Allosteric Small Molecule Antagonist of the Human Pituitary Adenylate Cyclase-Activating Polypeptide Receptor
Langer, Gernot, Scott, John, Lind, Christoffer, Otto, Christiane, Bothe, Ulrich, Laux-Biehlmann, Alexis, Müller, Jörg, le Roy, Beau, Irlbacher, Horst, Nowak-Reppel, Katrin, Schlüter, Anne, Davenport, Adam J, Slack, Mark, Bäurle, Stefan
Published in Molecular pharmacology (01.09.2023)
Published in Molecular pharmacology (01.09.2023)
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Journal Article
Preclinical models of endometriosis and interstitial cystitis/bladder pain syndrome: an Innovative Medicines Initiative-PainCare initiative to improve their value for translational research in pelvic pain
Nunez-Badinez, Paulina, De Leo, Bianca, Laux-Biehlmann, Alexis, Hoffmann, Anja, Zollner, Thomas M, Saunders, Philippa T K, Simitsidellis, Ioannis, Charrua, Ana, Cruz, Francisco, Gomez, Raul, Tejada, Miguel Angel, McMahon, Stephen B, Lo Re, Laure, Barthas, Florent, Vincent, Katy, Birch, Judy, Meijlink, Jane, Hummelshoj, Lone, Sweeney, Patrick J, Armstrong, J Douglas, Treede, Rolf-Detlef, Nagel, Jens
Published in Pain (Amsterdam) (01.09.2021)
Published in Pain (Amsterdam) (01.09.2021)
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Journal Article
Activation of CD8 + T Cells in Chronic Obstructive Pulmonary Disease Lung
Villaseñor-Altamirano, Ana B, Jain, Dhawal, Jeong, Yunju, Menon, Jaivardhan A, Kamiya, Mari, Haider, Hibah, Manandhar, Reshmi, Sheikh, Muhammad Dawood Amir, Athar, Humra, Merriam, Louis T, Ryu, Min Hyung, Sasaki, Takanori, Castaldi, Peter J, Rao, Deepak A, Sholl, Lynette M, Vivero, Marina, Hersh, Craig P, Zhou, Xiaobo, Veerkamp, Justus, Yun, Jeong H, Kim, Edy Y
Published in American journal of respiratory and critical care medicine (01.12.2023)
Published in American journal of respiratory and critical care medicine (01.12.2023)
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Journal Article
Neuropeptide S receptor 1 is a nonhormonal treatment target in endometriosis
Tapmeier, Thomas T, Rahmioglu, Nilufer, Lin, Jianghai, De Leo, Bianca, Obendorf, Maik, Raveendran, Muthuswamy, Fischer, Oliver M, Bafligil, Cemsel, Guo, Manman, Harris, Ronald Alan, Hess-Stumpp, Holger, Laux-Biehlmann, Alexis, Lowy, Ernesto, Lunter, Gerton, Malzahn, Jessica, Martin, Nicholas G, Martinez, Fernando O, Manek, Sanjiv, Mesch, Stefanie, Montgomery, Grant W, Morris, Andrew P, Nagel, Jens, Simmons, Heather A, Brocklebank, Denise, Shang, Catherine, Treloar, Susan, Wells, Graham, Becker, Christian M, Oppermann, Udo, Zollner, Thomas M, Kennedy, Stephen H, Kemnitz, Joseph W, Rogers, Jeffrey, Zondervan, Krina T
Published in Science translational medicine (25.08.2021)
Published in Science translational medicine (25.08.2021)
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Journal Article
Dynamic weight bearing as a non-reflexive method for the measurement of abdominal pain in mice
Laux-Biehlmann, A, Boyken, J, Dahllöf, H, Schmidt, N, Zollner, T M, Nagel, J
Published in European journal of pain (01.05.2016)
Published in European journal of pain (01.05.2016)
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