Eliapixant is a selective P2X3 receptor antagonist for the treatment of disorders associated with hypersensitive nerve fibers
Davenport, Adam J, Neagoe, Ioana, Bräuer, Nico, Koch, Markus, Rotgeri, Andrea, Nagel, Jens, Laux-Biehlmann, Alexis, Machet, Frederic, Coelho, Anne-Marie, Boyce, Susan, Carty, Nikisha, Gemkow, Mark J, Hess, Stephen D, Zollner, Thomas M, Fischer, Oliver M
Published in Scientific reports (06.10.2021)
Published in Scientific reports (06.10.2021)
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Stable isotope‐labelled morphine to study in vivo central and peripheral morphine glucuronidation and brain transport in tolerant mice
Weinsanto, Ivan, Laux‐Biehlmann, Alexis, Mouheiche, Jinane, Maduna, Tando, Delalande, François, Chavant, Virginie, Gabel, Florian, Darbon, Pascal, Charlet, Alexandre, Poisbeau, Pierrick, Lamshöft, Marc, Van Dorsselaer, Alain, Cianferani, Sarah, Parat, Marie‐Odile, Goumon, Yannick
Published in British journal of pharmacology (01.10.2018)
Published in British journal of pharmacology (01.10.2018)
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Journal Article
Menstruation pulls the trigger for inflammation and pain in endometriosis
Laux-Biehlmann, Alexis, d’Hooghe, Thomas, Zollner, Thomas M
Published in Trends in pharmacological sciences (Regular ed.) (01.05.2015)
Published in Trends in pharmacological sciences (Regular ed.) (01.05.2015)
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Discovery and Characterization of the Potent and Selective P2X4 Inhibitor N‑[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile
Werner, Stefan, Mesch, Stefanie, Hillig, Roman C, ter Laak, Antonius, Klint, Julie, Neagoe, Ioana, Laux-Biehlmann, Alexis, Dahllöf, Henrik, Bräuer, Nico, Puetter, Vera, Nubbemeyer, Reinhard, Schulz, Simone, Bairlein, Michaela, Zollner, Thomas M, Steinmeyer, Andreas
Published in Journal of medicinal chemistry (26.12.2019)
Published in Journal of medicinal chemistry (26.12.2019)
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Journal Article
Endogenous morphine levels are increased in sepsis: a partial implication of neutrophils
Glattard, Elise, Welters, Ingeborg D, Lavaux, Thomas, Muller, Arnaud H, Laux, Alexis, Zhang, Dan, Schmidt, Alexander R, Delalande, François, Laventie, Benoît-Joseph, Dirrig-Grosch, Sylvie, Colin, Didier A, Van Dorsselaer, Alain, Aunis, Dominique, Metz-Boutigue, Marie-Hélène, Schneider, Francis, Goumon, Yannick
Published in PloS one (20.01.2010)
Published in PloS one (20.01.2010)
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Journal Article
Anxiety-related behaviors without observation of generalized pain in a mouse model of endometriosis
Nunez-Badinez, Paulina, Laux-Biehlmann, Alexis, Hayward, Michael D, Buiakova, Olesia, Zollner, Thomas M, Nagel, Jens
Published in Frontiers in behavioral neuroscience (09.02.2023)
Published in Frontiers in behavioral neuroscience (09.02.2023)
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Journal Article
Endogenous morphine in SH-SY5Y cells and the mouse cerebellum
Muller, Arnaud, Glattard, Elise, Taleb, Omar, Kemmel, Véronique, Laux, Alexis, Miehe, Monique, Delalande, François, Roussel, Guy, Van Dorsselaer, Alain, Metz-Boutigue, Marie-Hélène, Aunis, Dominique, Goumon, Yannick
Published in PloS one (20.02.2008)
Published in PloS one (20.02.2008)
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Journal Article
Morphine Binds Creatine Kinase B and Inhibits Its Activity
Weinsanto, Ivan, Mouheiche, Jinane, Laux-Biehlmann, Alexis, Delalande, François, Marquette, Arnaud, Chavant, Virginie, Gabel, Florian, Cianferani, Sarah, Charlet, Alexandre, Parat, Marie-Odile, Goumon, Yannick
Published in Frontiers in cellular neuroscience (03.12.2018)
Published in Frontiers in cellular neuroscience (03.12.2018)
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Journal Article
Corrigendum: Morphine Binds Creatine Kinase B and Inhibits Its Activity
Weinsanto, Ivan, Mouheiche, Jinane, Laux-Biehlmann, Alexis, Delalande, François, Marquette, Arnaud, Chavant, Virginie, Gabel, Florian, Cianferani, Sarah, Charlet, Alexandre, Parat, Marie-Odile, Goumon, Yannick
Published in Frontiers in cellular neuroscience (02.07.2019)
Published in Frontiers in cellular neuroscience (02.07.2019)
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Journal Article
Abnormal Nociception and Opiate Sensitivity of STOP Null Mice Exhibiting Elevated Levels of the Endogenous Alkaloid Morphine
Charlet, Alexandre, Muller, Arnaud H, Laux, Alexis, Kemmel, Véronique, Schweitzer, Annie, Deloulme, Jean-Christophe, Stuber, Denise, Delalande, François, Bianchi, Enrica, Van Dorsselaer, Alain, Aunis, Dominique, Andrieux, Annie, Poisbeau, Pierrick, Goumon, Yannick
Published in Molecular pain (20.12.2010)
Published in Molecular pain (20.12.2010)
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Journal Article
Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions
Thézénas, Marie-Laëtitia, De Leo, Bianca, Laux-Biehlmann, Alexis, Bafligil, Cemsel, Elger, Bernd, Tapmeier, Thomas, Morten, Karl, Rahmioglu, Nilufer, Dakin, Stephanie G, Charles, Philip, Martinez, Fernando Estrada, Steers, Graham, Fischer, Oliver M, Mueller, Joerg, Hess-Stumpp, Holger, Steinmeyer, Andreas, Manek, Sanjiv, Zondervan, Krina T, Kennedy, Stephen, Becker, Christian M, Shang, Catherine, Zollner, Thomas M, Kessler, Benedikt M, Oppermann, Udo
Published in Scientific reports (30.01.2020)
Published in Scientific reports (30.01.2020)
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Journal Article
Author Correction: Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions
Thézénas, Marie-Laëtitia, De Leo, Bianca, Laux-Biehlmann, Alexis, Bafligil, Cemsel, Elger, Bernd, Tapmeier, Thomas, Morten, Karl, Rahmioglu, Nilufer, Dakin, Stephanie G, Charles, Philip, Martinez, Fernando Estrada, Steers, Graham, Fischer, Oliver M, Mueller, Joerg, Hess-Stumpp, Holger, Steinmeyer, Andreas, Manek, Sanjiv, Zondervan, Krina T, Kennedy, Stephen, Becker, Christian M, Shang, Catherine, Zollner, Thomas M, Kessler, Benedikt M, Oppermann, Udo
Published in Scientific reports (24.03.2020)
Published in Scientific reports (24.03.2020)
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Journal Article
Lithium reverses mechanical allodynia through a mu opioid-dependent mechanism
Weinsanto, Ivan, Mouheiche, Jinane, Laux-Biehlmann, Alexis, Aouad, Maya, Maduna, Tando, Petit-Demoulière, Nathalie, Chavant, Virginie, Poisbeau, Pierrick, Darbon, Pascal, Charlet, Alexandre, Giersch, Anne, Parat, Marie-Odile, Goumon, Yannick
Published in Molecular pain (01.01.2018)
Published in Molecular pain (01.01.2018)
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Journal Article
Comparison of serum and lithium‐heparinate plasma for the accurate measurements of endogenous and exogenous morphine concentrations
Laux‐Biehlmann, Alexis, Gräfe, Nadja, Mouheiche, Jinane, Stuber, Denise, Welters, Ingeborg D., Delalande, François, Poisbeau, Pierrick, Garnero, Patrick, Metz‐Boutigue, Marie‐Hélène, Schneider, Francis, Goumon, Yannick
Published in British journal of clinical pharmacology (01.08.2012)
Published in British journal of clinical pharmacology (01.08.2012)
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Journal Article
Endogenous morphine-6-glucuronide (M6G) is present in the plasma of patients: Validation of a specific anti-M6G antibody for clinical and basic research
Laux-Biehlmann, Alexis, Chung, Hélène, Mouheiche, Jinane, Vérièpe, Julie, Delalande, François, Lamshöft, Marc, Welters, Ingeborg D., Soldevila, Stéphanie, Bazin, Hervé, Lamarque, Laurent, Dorsselaer, Alain Van, Poisbeau, Pierrick, Schneider, Francis, Goumon, Yannick, Garnero, Patrick
Published in BioFactors (Oxford) (01.01.2014)
Published in BioFactors (Oxford) (01.01.2014)
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Journal Article
Localization of endogenous morphine-like compounds in the mouse spinal cord
Laux, Alexis, Delalande, François, Mouheiche, Jinane, Stuber, Denise, Van Dorsselaer, Alain, Bianchi, Enrica, Bezard, Erwan, Poisbeau, Pierrick, Goumon, Yannick
Published in Journal of comparative neurology (1911) (01.05.2012)
Published in Journal of comparative neurology (1911) (01.05.2012)
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Journal Article
Mapping of endogenous morphine-like compounds in the adult mouse brain: Evidence of their localization in astrocytes and GABAergic cells
Laux, Alexis, Muller, Arnaud H., Miehe, Monique, Dirrig-Grosch, Sylvie, Deloulme, Jean Christophe, Delalande, François, Stuber, Denise, Sage, Dominique, Van Dorsselaer, Alain, Poisbeau, Pierrick, Aunis, Dominique, Goumon, Yannick
Published in Journal of comparative neurology (1911) (15.08.2011)
Published in Journal of comparative neurology (1911) (15.08.2011)
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Journal Article
Endogenous morphine-like compound immunoreactivity increases in parkinsonism
Charron, Giselle, Doudnikoff, Evelyne, Laux, Alexis, Berthet, Amandine, Porras, Gregory, Canron, Marie-Hélène, Barroso-Chinea, Pedro, Li, Qin, Qin, Chuan, Nosten-Bertrand, Marika, Giros, Bruno, Delalande, François, Van Dorsselaer, Alain, Vital, Anne, Goumon, Yannick, Bezard, Erwan
Published in Brain (London, England : 1878) (01.08.2011)
Published in Brain (London, England : 1878) (01.08.2011)
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Journal Article
Characterization of human and bovine phosphatidylethanolamine-binding protein (PEBP/RKIP) interactions with morphine and morphine-glucuronides determined by noncovalent mass spectrometry
Atmanene, Cédric, Laux, Alexis, Glattard, Elise, Muller, Arnaud, Schoentgen, Françoise, Metz-Boutigue, Marie-Hélène, Aunis, Dominique, Van Dorsselaer, Alain, Stefano, George B, Sanglier-Cianférani, Sarah, Goumon, Yannick
Published in Medical science monitor (01.07.2009)
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Published in Medical science monitor (01.07.2009)
Journal Article
Discovery of BAY-390, a Selective CNS Penetrant Chemical Probe as Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonist
Mesch, Stefanie, Walter, Daryl, Laux-Biehlmann, Alexis, Basting, Daniel, Flanagan, Stuart, Miyatake Ondozabal, Hideki, Bäurle, Stefan, Pearson, Christopher, Jenkins, James, Elves, Philip, Hess, Stephen, Coelho, Anne-Marie, Rotgeri, Andrea, Bothe, Ulrich, Nawaz, Schanila, Zollner, Thomas M., Steinmeyer, Andreas
Published in Journal of medicinal chemistry (26.01.2023)
Published in Journal of medicinal chemistry (26.01.2023)
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