Impaired Gene and Protein Expression of Exocytotic Soluble N-Ethylmaleimide Attachment Protein Receptor Complex Proteins in Pancreatic Islets of Type 2 Diabetic Patients
OSTENSON, Claes-Goran, GAISANO, Herbert, SHEU, Laura, TIBELL, Annika, BARTFAI, Tamas
Published in Diabetes (New York, N.Y.) (01.02.2006)
Published in Diabetes (New York, N.Y.) (01.02.2006)
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Interaction Between Munc13-1 and RIM Is Critical for Glucagon-Like Peptide-1–Mediated Rescue of Exocytotic Defects in Munc13-1–Deficient Pancreatic β-Cells
Kwan, Edwin P, Xie, Li, Sheu, Laura, Ohtsuka, Toshihisa, Gaisano, Herbert Y
Published in Diabetes (New York, N.Y.) (01.10.2007)
Published in Diabetes (New York, N.Y.) (01.10.2007)
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Caspase-3-Dependent β-Cell Apoptosis in the Initiation of Autoimmune Diabetes Mellitus
Liadis, Nicole, Murakami, Kiichi, Eweida, Mohamed, Elford, Alisha R., Sheu, Laura, Gaisano, Herbert Y., Hakem, Razqallah, Ohashi, Pamela S., Woo, Minna
Published in Molecular and Cellular Biology (01.05.2005)
Published in Molecular and Cellular Biology (01.05.2005)
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Distinct In Vivo Roles of Caspase-8 in β-Cells in Physiological and Diabetes Models
Liadis, Nicole, Salmena, Leonardo, Kwan, Edwin, Tajmir, Panteha, Schroer, Stephanie A, Radziszewska, Anna, Li, Xie, Sheu, Laura, Eweida, Mohamed, Xu, Shilong, Gaisano, Herbert Y, Hakem, Razqallah, Woo, Minna
Published in Diabetes (New York, N.Y.) (01.09.2007)
Published in Diabetes (New York, N.Y.) (01.09.2007)
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Munc13-1 Deficiency Reduces Insulin Secretion and Causes Abnormal Glucose Tolerance
KWAN, Edwin P, LI XIE, SHEU, Laura, NOLAN, Christopher J, PRENTKI, Marc, BETZ, Andrea, BROSE, Nils, GAISANO, Herbert Y
Published in Diabetes (New York, N.Y.) (01.05.2006)
Published in Diabetes (New York, N.Y.) (01.05.2006)
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Electrophysiological Characterization of Pancreatic Islet Cells in the Mouse Insulin Promoter-Green Fluorescent Protein Mouse
Leung, Yuk M, Ahmed, Ishtiaq, Sheu, Laura, Tsushima, Robert G, Diamant, Nicholas E, Hara, Manami, Gaisano, Herbert Y
Published in Endocrinology (Philadelphia) (01.11.2005)
Published in Endocrinology (Philadelphia) (01.11.2005)
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Syntaxin 1A Binds to the Cytoplasmic C Terminus of Kv2.1 to Regulate Channel Gating and Trafficking
Leung, Yuk M., Kang, Youhou, Gao, Xiaodong, Xia, Fuzhen, Xie, Huanli, Sheu, Laura, Tsuk, Sharon, Lotan, Ilana, Tsushima, Robert G., Gaisano, Herbert Y.
Published in The Journal of biological chemistry (09.05.2003)
Published in The Journal of biological chemistry (09.05.2003)
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Regulation of Insulin Exocytosis by Munc13-1
Sheu, Laura, Pasyk, Eva A., Ji, Junzhi, Huang, Xiaohang, Gao, Xiaodong, Varoqueaux, Frederique, Brose, Nils, Gaisano, Herbert Y.
Published in The Journal of biological chemistry (25.07.2003)
Published in The Journal of biological chemistry (25.07.2003)
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Transgenic Mouse Overexpressing Syntaxin-1A as a Diabetes Model
LAM, Patrick P. L, LEUNG, Yuk-Man, SHEU, Laura, ELLIS, James, TSUSHIMA, Robert G, OSBORNE, Lucy R, GAISANO, Herbert Y
Published in Diabetes (New York, N.Y.) (01.09.2005)
Published in Diabetes (New York, N.Y.) (01.09.2005)
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Modulation of L-Type Ca2+ Channels by Distinct Domains Within SNAP-25
Ji, Junzhi, Yang, Shao-Nian, Huang, Xiaohang, Li, Xidan, Sheu, Laura, Diamant, Nicholas, Berggren, Per-Olof, Gaisano, Herbert Y.
Published in Diabetes (New York, N.Y.) (01.05.2002)
Published in Diabetes (New York, N.Y.) (01.05.2002)
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Target Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptors (t-SNAREs) Differently Regulate Activation and Inactivation Gating of Kv2.2 and Kv2.1: Implications on Pancreatic Islet Cell Kv Channels
Wolf-Goldberg, Tami, Michaelevski, Izhak, Sheu, Laura, Gaisano, Herbert Y., Chikvashvili, Dodo, Lotan, Ilana
Published in Molecular pharmacology (01.09.2006)
Published in Molecular pharmacology (01.09.2006)
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Syntaxin-1A Inhibits Cardiac KATP Channels by Its Actions on Nucleotide Binding Folds 1 and 2 of Sulfonylurea Receptor 2A
Kang, Youhou, Leung, Yuk-Man, Manning-Fox, Jocelyn E, Xia, Fuzhen, Xie, Huanli, Sheu, Laura, Tsushima, Robert G, Light, Peter E, Gaisano, Herbert Y
Published in The Journal of biological chemistry (05.11.2004)
Published in The Journal of biological chemistry (05.11.2004)
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H3 Domain of Syntaxin 1A Inhibits KATP Channels by Its Actions on the Sulfonylurea Receptor 1 Nucleotide-Binding Folds-1 and -2
Cui, Ningren, Kang, Youhou, He, Yan, Leung, Yuk-Man, Xie, Huanli, Pasyk, Ewa A., Gao, Xiaodong, Sheu, Laura, Hansen, John B., Wahl, Philip, Tsushima, Robert G., Gaisano, Herbert Y.
Published in The Journal of biological chemistry (17.12.2004)
Published in The Journal of biological chemistry (17.12.2004)
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Effects of palmitate on insulin secretion and exocytotic proteins in islets of diabetic Goto-Kakizaki rats
Ostenson, Claes-Göran, Chen, Jie, Sheu, Laura, Gaisano, Herbert Y
Published in Pancreas (01.04.2007)
Published in Pancreas (01.04.2007)
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The 25-kDa Synaptosome-associated Protein (SNAP-25) Binds and Inhibits Delayed Rectifier Potassium Channels in Secretory Cells
Ji, Junzhi, Tsuk, Sharon, Salapatek, Anne Marie F., Huang, Xiaohang, Chikvashvili, Dodo, Pasyk, Ewa A., Kang, Youhou, Sheu, Laura, Tsushima, Robert, Diamant, Nicholas, Trimble, William S., Lotan, Ilana, Gaisano, Herbert Y.
Published in The Journal of biological chemistry (07.06.2002)
Published in The Journal of biological chemistry (07.06.2002)
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Supramaximal cholecystokinin displaces Munc18c from the pancreatic acinar basal surface, redirecting apical exocytosis to the basal membrane
Gaisano, Herbert Y., Lutz, Manfred P., Leser, Juergen, Sheu, Laura, Lynch, Grit, Tang, Lan, Tamori, Yoshikazu, Trimble, William S., Salapatek, Anne Marie F.
Published in The Journal of clinical investigation (01.12.2001)
Published in The Journal of clinical investigation (01.12.2001)
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Disruption of pancreatic beta-cell lipid rafts modifies Kv2.1 channel gating and insulin exocytosis
Xia, Fuzhen, Gao, Xiaodong, Kwan, Edwin, Lam, Patrick P L, Chan, Lillian, Sy, Keiyan, Sheu, Laura, Wheeler, Michael B, Gaisano, Herbert Y, Tsushima, Robert G
Published in The Journal of biological chemistry (04.06.2004)
Published in The Journal of biological chemistry (04.06.2004)
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