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Breen, Danna M., Kim, Hanna, Bennett, Donald, Calle, Roberto A., Collins, Susie, Esquejo, Ryan M., He, Tao, Joaquim, Stephanie, Joyce, Alison, Lambert, Matthew, Lin, Laura, Pettersen, Betty, Qiao, Shuxi, Rossulek, Michelle, Weber, Gregory, Wu, Zhidan, Zhang, Bei B., Birnbaum, Morris J.
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The chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in C. elegans
Emerson, Felicity J., Chiu, Caitlin, Lin, Laura Y., Riedel, Christian G., Zhu, Ming, Lee, Siu Sylvia
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Crystal Structure of a Human IκB Kinase β Asymmetric Dimer
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Published in PloS one (07.05.2020)
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Establishing in vitro in vivo correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics
Avery, Lindsay B, Wade, Jason, Wang, Mengmeng, Tam, Amy, King, Amy, Piche-Nicholas, Nicole, Kavosi, Mania S, Penn, Steve, Cirelli, David, Kurz, Jeffrey C, Zhang, Minlei, Cunningham, Orla, Jones, Rhys, Fennell, Brian J, McDonnell, Barry, Sakorafas, Paul, Apgar, James, Finlay, William J, Lin, Laura, Bloom, Laird, O'Hara, Denise M
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Cysteine metabolic engineering and selective disulfide reduction produce superior antibody-drug-conjugates
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Tyrosine Sulfation at Antibody Light Chain CDR-1 Increases Binding Affinity and Neutralization Potency to Interleukine-4
D'Antona, Aaron M, Lee, Julie M, Zhang, Melvin, Friedman, Clarence, He, Tao, Mosyak, Lidia, Bennett, Eric, Lin, Laura, Silverman, Maddison, Cometa, Funi, Meade, Caryl, Hageman, Tyler, Sousa, Eric, Cohen, Justin, Marquette, Kimberly, Ferguson, Darren, Zhong, Xiaotian
Published in International journal of molecular sciences (01.02.2024)
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Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation
Fung, Ella, Kang, Liya, Sapashnik, Diana, Benard, Susan, Sievers, Annette, Liu, Yan, Yan, Guoying, Zhou, Jing, Rodriguez, Linette, Ma, Weijun, Stochaj, Wayne R., LaVallie, Edward, Wroblewska, Liliana, Kelleher, Kerry, Tam, Amy, Bezy, Olivier, Breen, Danna, Chabot, Jeffrey R., He, Tao, Lin, Laura, Wu, Zhidan, Mosyak, Lidia
Published in Scientific reports (26.04.2021)
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Transient CHO expression platform for robust antibody production and its enhanced N‐glycan sialylation on therapeutic glycoproteins
Zhong, Xiaotian, Ma, Weijun, Meade, Caryl L., Tam, Amy S., Llewellyn, Eliza, Cornell, Richard, Cote, Kaffa, Scarcelli, John J., Marshall, Jeffrey K., Tzvetkova, Boriana, Figueroa, Bruno, DiNino, Dana, Sievers, Annette, Lee, Christopher, Guo, Jane, Mahan, Evan, Francis, Christopher, Lam, Khetemenee, D'Antona, Aaron M., Zollner, Richard, Zhu, Hongli L., Kriz, Ron, Somers, Will, Lin, Laura
Published in Biotechnology progress (01.01.2019)
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Reduction of therapeutic antibody self-association using yeast-display selections and machine learning
Makowski, Emily K, Chen, Hongwei, Lambert, Matthew, Bennett, Eric M, Eschmann, Nicole S, Zhang, Yulei, Zupancic, Jennifer M, Desai, Alec A, Smith, Matthew D, Lou, Wenjia, Fernando, Amendra, Tully, Timothy, Gallo, Christopher J, Lin, Laura, Tessier, Peter M
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Engineering a Monomeric Fc Domain Modality by N-Glycosylation for the Half-life Extension of Biotherapeutics
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Published in The Journal of biological chemistry (07.06.2013)
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In vitro affinity optimization of an anti-BDNF monoclonal antibody translates to improved potency in targeting chronic pain states in vivo
Stack, Edwina, McMurray, Sheridan, McMurray, Gordon, Wade, Jason, Clark, Melissa, Young, Gareth, Marquette, Kim, Jain, Sadhana, Kelleher, Kerry, Chen, Ting, Lin, Qingcong, Bloom, Laird, Lin, Laura, Finlay, William, Suzuki, Rie, Cunningham, Orla
Published in mAbs (01.01.2020)
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Addressing the Chinese food stereotype in health care
Lin, Laura C, Chang, Enchi K, He, Karen, Huang, Melody, Richards, Jeremy B.
Published in The clinical teacher (01.10.2020)
Published in The clinical teacher (01.10.2020)
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Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors
Root, Adam R, Guntas, Gurkan, Katragadda, Madan, Apgar, James R, Narula, Jatin, Chang, Chew Shun, Hanscom, Sara, McKenna, Matthew, Wade, Jason, Meade, Caryl, Ma, Weijun, Guo, Yongjing, Liu, Yan, Duan, Weili, Hendershot, Claire, King, Amy C, Zhang, Yan, Sousa, Eric, Tam, Amy, Benard, Susan, Yang, Han, Kelleher, Kerry, Jin, Fang, Piche-Nicholas, Nicole, Keating, Sinead E, Narciandi, Fernando, Lawrence-Henderson, Rosemary, Arai, Maya, Stochaj, Wayne R, Svenson, Kristine, Mosyak, Lidia, Lam, Khetemcnee, Francis, Christopher, Marquette, Kimberly, Wroblewska, Liliana, Zhu, H Lily, Sheehan, Alfredo Darmanin, LaVallie, Edward R, D'Antona, Aaron M, Betts, Alison, King, Lindsay, Rosfjord, Edward, Cunningham, Orla, Lin, Laura, Sapra, Puja, Tchistiakova, Lioudmila, Mathur, Divya, Bloom, Laird
Published in mAbs (01.01.2021)
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Exploring Parametric and Mechanistic Differences between Expi293FTM and ExpiCHO-STM Cells for Transient Antibody Production Optimization
Zhou, Jing, Yan, Guoying Grace, Cluckey, David, Meade, Caryl, Ruth, Margaret, Sorm, Rhady, Tam, Amy S., Lim, Sean, Petridis, Constantine, Lin, Laura, D’Antona, Aaron M., Zhong, Xiaotian
Published in Antibodies (Basel) (10.08.2023)
Published in Antibodies (Basel) (10.08.2023)
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Faster in vivo clearance of human embryonic kidney than Chinese hamster ovary cell derived protein: Role of glycan mediated clearance
Wang, Mengmeng, Ishino, Tetsuya, Joyce, Alison, Tam, Amy, Duan, Weili, Lin, Laura, Somers, William S., Kriz, Ronald, O'Hara, Denise M.
Published in Journal of bioscience and bioengineering (01.06.2015)
Published in Journal of bioscience and bioengineering (01.06.2015)
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Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5
Mosyak, Lidia, Georgiadis, Katy, Shane, Tania, Svenson, Kristine, Hebert, Tracy, McDonagh, Thomas, Mackie, Stewart, Olland, Stephane, Lin, Laura, Zhong, Xiaotian, Kriz, Ronald, Reifenberg, Erica L., Collins‐Racie, Lisa A., Corcoran, Christopher, Freeman, Bethany, Zollner, Richard, Marvell, Tod, Vera, Matthew, Sum, Phaik‐Eng, Lavallie, Edward R., Stahl, Mark, Somers, William
Published in Protein science (01.01.2008)
Published in Protein science (01.01.2008)
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