Structure–activity relationships of the peptide deformylase inhibitor BB-3497: modification of the methylene spacer and the P1′ side chain
Davies, Stephen J., Ayscough, Andrew P., Beckett, R.Paul, Bragg, Ryan A., Clements, John M., Doel, Sheila, Grew, Christine, Launchbury, Steven B., Perkins, Gemma M., Pratt, Lisa M., Smith, Helen K., Spavold, Zoë M., Thomas, S.Wayne, Todd, Richard S., Whittaker, Mark
Published in Bioorganic & medicinal chemistry letters (18.08.2003)
Published in Bioorganic & medicinal chemistry letters (18.08.2003)
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Journal Article
Structure–activity relationships of the peptide deformylase inhibitor BB-3497: modification of the metal binding group
Smith, Helen K., Beckett, R.Paul, Clements, John M., Doel, Sheila, East, Stephen P., Launchbury, Steven B., Pratt, Lisa M., Spavold, Zoë M., Thomas, Wayne, Todd, Richard S., Whittaker, Mark
Published in Bioorganic & medicinal chemistry letters (16.12.2002)
Published in Bioorganic & medicinal chemistry letters (16.12.2002)
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Journal Article
Asymmetric synthesis of bb-3497—A potent peptide deformylase inhibitor
Pratt, Lisa M, Beckett, R.Paul, Davies, Stephen J, Launchbury, Steven B, Miller, Andrew, Spavold, Zoe M, Todd, Richard S, Whittaker, Mark
Published in Bioorganic & medicinal chemistry letters (08.10.2001)
Published in Bioorganic & medicinal chemistry letters (08.10.2001)
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Journal Article
Total synthesis of dihydromevinolin and a series of related 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors
Blackwell, Christopher M, Davidson, Alan H, Launchbury, Steven B, Lewis, Christopher N, Morrice, Elizabeth M, Reeve, Maxwell M, Roffey, Jonathon A. R, Tipping, Andrew S, Todd, Richard S
Published in Journal of organic chemistry (01.10.1992)
Published in Journal of organic chemistry (01.10.1992)
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An improved procedure for the introduction of the .delta.-lactone portion of HMG-CoA reductase inhibitors
Blackwell, Christopher M, Davidson, Alan H, Launchbury, Steven B, Lewis, Christopher N, Morrice, Elizabeth M, Reeve, Maxwell M, Roffey, Jonathon A. R, Tipping, Andrew S, Todd, Richard S
Published in Journal of organic chemistry (01.03.1992)
Published in Journal of organic chemistry (01.03.1992)
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