IDO1 in cancer: a Gemini of immune checkpoints
Zhai, Lijie, Ladomersky, Erik, Lenzen, Alicia, Nguyen, Brenda, Patel, Ricky, Lauing, Kristen L, Wu, Meijing, Wainwright, Derek A
Published in Cellular & molecular immunology (01.05.2018)
Published in Cellular & molecular immunology (01.05.2018)
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Journal Article
Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies
Zhai, Lijie, Bell, April, Ladomersky, Erik, Lauing, Kristen L, Bollu, Lakshmi, Sosman, Jeffrey A, Zhang, Bin, Wu, Jennifer D, Miller, Stephen D, Meeks, Joshua J, Lukas, Rimas V, Wyatt, Eugene, Doglio, Lynn, Schiltz, Gary E, McCusker, Robert H, Wainwright, Derek A
Published in Frontiers in immunology (16.06.2020)
Published in Frontiers in immunology (16.06.2020)
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Journal Article
The Coincidence Between Increasing Age, Immunosuppression, and the Incidence of Patients With Glioblastoma
Ladomersky, Erik, Scholtens, Denise M, Kocherginsky, Masha, Hibler, Elizabeth A, Bartom, Elizabeth T, Otto-Meyer, Sebastian, Zhai, Lijie, Lauing, Kristen L, Choi, Jaehyuk, Sosman, Jeffrey A, Wu, Jennifer D, Zhang, Bin, Lukas, Rimas V, Wainwright, Derek A
Published in Frontiers in pharmacology (27.03.2019)
Published in Frontiers in pharmacology (27.03.2019)
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Journal Article
Aggrecan is required for growth plate cytoarchitecture and differentiation
Lauing, Kristen L., Cortes, Mauricio, Domowicz, Miriam S., Henry, Judith G., Baria, Alexis T., Schwartz, Nancy B.
Published in Developmental biology (15.12.2014)
Published in Developmental biology (15.12.2014)
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Journal Article
The role of IDO in brain tumor immunotherapy
Zhai, Lijie, Lauing, Kristen L., Chang, Alan L., Dey, Mahua, Qian, Jun, Cheng, Yu, Lesniak, Maciej S., Wainwright, Derek A.
Published in Journal of neuro-oncology (01.07.2015)
Published in Journal of neuro-oncology (01.07.2015)
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Journal Article
Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma
Zhai, Lijie, Ladomersky, Erik, Dostal, Carlos R, Lauing, Kristen, Swoap, Kathleen, Billingham, Leah K, Gritsina, Galina, Wu, Meijing, McCusker, Robert H, Binder, David C, Wainwright, Derek A
Published in Brain, behavior, and immunity (01.05.2017)
Published in Brain, behavior, and immunity (01.05.2017)
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Journal Article
Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry
Nguyen, Teresa T, Shin, Dong Ho, Sohoni, Sagar, Singh, Sanjay K, Rivera-Molina, Yisel, Jiang, Hong, Fan, Xuejun, Gumin, Joy, Lang, Frederick F, Alvarez-Breckenridge, Christopher, Godoy-Vitorino, Filipa, Zhu, Lisha, Zheng, W Jim, Zhai, Lijie, Ladomersky, Erik, Lauing, Kristen L, Alonso, Marta M, Wainwright, Derek A, Gomez-Manzano, Candelaria, Fueyo, Juan
Published in Journal for immunotherapy of cancer (01.07.2022)
Published in Journal for immunotherapy of cancer (01.07.2022)
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Journal Article
A retrospective survival analysis of Glioblastoma patients treated with selective serotonin reuptake inhibitors
Otto-Meyer, Sebastian, DeFaccio, Rian, Dussold, Corey, Ladomersky, Erik, Zhai, Lijie, Lauing, Kristen L., Bollu, Lakshmi R., Amidei, Christina, Lukas, Rimas V., Scholtens, Denise M., Wainwright, Derek A.
Published in Brain, behavior, & immunity. Health (01.02.2020)
Published in Brain, behavior, & immunity. Health (01.02.2020)
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Journal Article
Age-stratified comorbid and pharmacologic analysis of patients with glioblastoma
Rabin, Erik E., Huang, Jonathan, Kim, Miri, Mozny, Andreas, Lauing, Kristen L., Penco-Campillo, Manon, Zhai, Lijie, Bommi, Prashant, Mi, Xinlei, Power, Erica A., Prabhu, Vikram C., Anderson, Douglas E., Barton, Kevin P., Walunas, Theresa L., Schiltz, Gary E., Amidei, Christina, Sanchez-Gomez, Pilar, Thakkar, Jigisha P., Lukas, Rimas V., Wainwright, Derek A.
Published in Brain, behavior, & immunity. Health (01.07.2024)
Published in Brain, behavior, & immunity. Health (01.07.2024)
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Journal Article
Commentary: preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma by Garg et al. (2017)
Zhai, Lijie, Ladomersky, Erik, Lauing, Kristen L., Wu, Meijing, Scholtens, Denise M., Savoor, Rohan, Zhang, Bin, Wu, Jennifer D., Horbinski, Craig, Lukas, Rimas V., Binder, David C., Wainwright, Derek A.
Published in Oncoimmunology (04.03.2019)
Published in Oncoimmunology (04.03.2019)
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Journal Article
A systematic review of pharmacologic treatment efficacy for depression in older patients with cancer
Rabin, Erik E., Kim, Miri, Mozny, Andreas, Cardoza, Krislyn, Bell, April C., Zhai, Lijie, Bommi, Prashant, Lauing, Kristen L., King, Amanda L., Armstrong, Terri S., Walunas, Theresa L., Fang, Deyu, Roy, Ishan, Peipert, John D., Sieg, Erica, Mi, Xinlei, Amidei, Christina, Lukas, Rimas V., Wainwright, Derek A.
Published in Brain, behavior, & immunity. Health (01.05.2022)
Published in Brain, behavior, & immunity. Health (01.05.2022)
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Journal Article
Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma
Zhai, Lijie, Bell, April, Ladomersky, Erik, Lauing, Kristen L, Bollu, Lakshmi, Nguyen, Brenda, Genet, Matthew, Kim, Miri, Chen, Peiwen, Mi, Xinlei, Wu, Jennifer D, Schipma, Matthew J, Wray, Brian, Griffiths, John, Unwin, Richard D, Clark, Simon J, Acharya, Rajesh, Bao, Riyue, Horbinski, Craig, Lukas, Rimas V, Schiltz, Gary E, Wainwright, Derek A
Published in Clinical cancer research (01.12.2021)
Published in Clinical cancer research (01.12.2021)
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Journal Article
Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival
Zhai, Lijie, Ladomersky, Erik, Lauing, Kristen L, Wu, Meijing, Genet, Matthew, Gritsina, Galina, Győrffy, Balázs, Brastianos, Priscilla K, Binder, David C, Sosman, Jeffrey A, Giles, Francis J, James, Charles D, Horbinski, Craig, Stupp, Roger, Wainwright, Derek A
Published in Clinical cancer research (01.11.2017)
Published in Clinical cancer research (01.11.2017)
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Journal Article
IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma
Ladomersky, Erik, Zhai, Lijie, Lenzen, Alicia, Lauing, Kristen L, Qian, Jun, Scholtens, Denise M, Gritsina, Galina, Sun, Xuebing, Liu, Ye, Yu, Fenglong, Gong, Wenfeng, Liu, Yong, Jiang, Beibei, Tang, Tristin, Patel, Ricky, Platanias, Leonidas C, James, C David, Stupp, Roger, Lukas, Rimas V, Binder, David C, Wainwright, Derek A
Published in Clinical cancer research (01.06.2018)
Published in Clinical cancer research (01.06.2018)
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Journal Article
Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma
Ladomersky, Erik, Zhai, Lijie, Lauing, Kristen L, Bell, April, Xu, Jiahui, Kocherginsky, Masha, Zhang, Bin, Wu, Jennifer D, Podojil, Joseph R, Platanias, Leonidas C, Mochizuki, Aaron Y, Prins, Robert M, Kumthekar, Priya, Raizer, Jeffrey J, Dixit, Karan, Lukas, Rimas V, Horbinski, Craig, Wei, Min, Zhou, Changyou, Pawelec, Graham, Campisi, Judith, Grohmann, Ursula, Prendergast, George C, Munn, David H, Wainwright, Derek A
Published in Clinical cancer research (01.10.2020)
Published in Clinical cancer research (01.10.2020)
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Journal Article
Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma
Bollu, Lakshmi R., Bommi, Prashant V., Monsen, Paige J., Zhai, Lijie, Lauing, Kristen L., Bell, April, Kim, Miri, Ladomersky, Erik, Yang, Xinyu, Platanias, Leonidas C., Matei, Daniela E., Bonini, Marcelo G., Munshi, Hidayatullah G., Hashizume, Rintaro, Wu, Jennifer D., Zhang, Bin, James, Charles David, Chen, Peiwen, Kocherginsky, Masha, Horbinski, Craig, Cameron, Michael D., Grigorescu, Arabela A., Yamini, Bakhtiar, Lukas, Rimas V., Schiltz, Gary E., Wainwright, Derek A.
Published in Journal of medicinal chemistry (08.12.2022)
Published in Journal of medicinal chemistry (08.12.2022)
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Journal Article
Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence
Johnson, Margaret, Bell, April, Lauing, Kristen L, Ladomersky, Erik, Zhai, Lijie, Penco-Campillo, Manon, Shah, Yajas, Mauer, Elizabeth, Xiu, Joanne, Nicolaides, Theodore, Drumm, Michael, McCortney, Kathleen, Elemento, Olivier, Kim, Miri, Bommi, Prashant, Low, Justin T, Memon, Ruba, Wu, Jennifer, Zhao, Junfei, Mi, Xinlei, Glantz, Michael J, Sengupta, Soma, Castro, Brandyn, Yamini, Bakhtiar, Horbinski, Craig, Baker, Darren J, Walunas, Theresa L, Schiltz, Gary E, Lukas, Rimas V, Wainwright, Derek A
Published in Clinical cancer research (01.12.2023)
Published in Clinical cancer research (01.12.2023)
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