Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting
Alkan, H. Furkan, Walter, Katharina E., Luengo, Alba, Madreiter-Sokolowski, Corina T., Stryeck, Sarah, Lau, Allison N., Al-Zoughbi, Wael, Lewis, Caroline A., Thomas, Craig J., Hoefler, Gerald, Graier, Wolfgang F., Madl, Tobias, Vander Heiden, Matthew G., Bogner-Strauss, Juliane G.
Published in Cell metabolism (06.11.2018)
Published in Cell metabolism (06.11.2018)
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Suppression of pancreatic ductal adenocarcinoma growth and metastasis by fibrillar collagens produced selectively by tumor cells
Tian, Chenxi, Huang, Ying, Clauser, Karl R., Rickelt, Steffen, Lau, Allison N., Carr, Steven A., Vander Heiden, Matthew G., Hynes, Richard O.
Published in Nature communications (20.04.2021)
Published in Nature communications (20.04.2021)
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Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression
Francescone, Ralph, Barbosa Vendramini-Costa, Débora, Franco-Barraza, Janusz, Wagner, Jessica, Muir, Alexander, Lau, Allison N, Gabitova, Linara, Pazina, Tatiana, Gupta, Sapna, Luong, Tiffany, Rollins, Dustin, Malik, Ruchi, Thapa, Roshan J, Restifo, Diana, Zhou, Yan, Cai, Kathy Q, Hensley, Harvey H, Tan, Yinfei, Kruger, Warren D, Devarajan, Karthik, Balachandran, Siddharth, Klein-Szanto, Andres J, Wang, Huamin, El-Deiry, Wafik S, Vander Heiden, Matthew G, Peri, Suraj, Campbell, Kerry S, Astsaturov, Igor, Cukierman, Edna
Published in Cancer discovery (01.02.2021)
Published in Cancer discovery (01.02.2021)
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Bronchioalveolar stem cells increase after mesenchymal stromal cell treatment in a mouse model of bronchopulmonary dysplasia
Tropea, Kristen A, Leder, Eva, Aslam, Muhammad, Lau, Allison N, Raiser, David M, Lee, Joo-Hyeon, Balasubramaniam, Vivek, Fredenburgh, Laura E, Alex Mitsialis, S, Kourembanas, Stella, Kim, Carla F
Published in American journal of physiology. Lung cellular and molecular physiology (01.05.2012)
Published in American journal of physiology. Lung cellular and molecular physiology (01.05.2012)
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Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma
Lau, Allison N, Li, Zhaoqi, Danai, Laura V, Westermark, Anna M, Darnell, Alicia M, Ferreira, Raphael, Gocheva, Vasilena, Sivanand, Sharanya, Lien, Evan C, Sapp, Kiera M, Mayers, Jared R, Biffi, Giulia, Chin, Christopher R, Davidson, Shawn M, Tuveson, David A, Jacks, Tyler, Matheson, Nicholas J, Yilmaz, Omer, Vander Heiden, Matthew G
Published in eLife (10.07.2020)
Published in eLife (10.07.2020)
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Primary Tumor Genotype Is an Important Determinant in Identification of Lung Cancer Propagating Cells
Curtis, Stephen J., Sinkevicius, Kerstin W., Li, Danan, Lau, Allison N., Roach, Rebecca R., Zamponi, Raffaella, Woolfenden, Amber E., Kirsch, David G., Wong, Kwok-Kin, Kim, Carla F.
Published in Cell stem cell (02.07.2010)
Published in Cell stem cell (02.07.2010)
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Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis
Sinkevicius, Kerstin W., Kriegel, Christina, Bellaria, Kelly J., Lee, Jaewon, Lau, Allison N., Leeman, Kristen T., Zhou, Pengcheng, Beede, Alexander M., Fillmore, Christine M., Caswell, Deborah, Barrios, Juliana, Wong, Kwok-Kin, Sholl, Lynette M., Schlaeger, Thorsten M., Bronson, Roderick T., Chirieac, Lucian R., Winslow, Monte M., Haigis, Marcia C., Kim, Carla F.
Published in Proceedings of the National Academy of Sciences - PNAS (15.07.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (15.07.2014)
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Journal Article
Lung Stem Cell Self-Renewal Relies on BMI1-Dependent Control of Expression at Imprinted Loci
Zacharek, Sima J., Fillmore, Christine M., Lau, Allison N., Gludish, David W., Chou, Alan, Ho, Joshua W.K., Zamponi, Raffaella, Gazit, Roi, Bock, Christoph, Jäger, Natalie, Smith, Zachary D., Kim, Tae-min, Saunders, Arven H., Wong, Janice, Lee, Joo-Hyeon, Roach, Rebecca R., Rossi, Derrick J., Meissner, Alex, Gimelbrant, Alexander A., Park, Peter J., Kim, Carla F.
Published in Cell stem cell (02.09.2011)
Published in Cell stem cell (02.09.2011)
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Journal Article
Increased PHGDH expression promotes aberrant melanin accumulation
Mattaini, Katherine R, Sullivan, Mark R, Lau, Allison N, Fiske, Brian P, Bronson, Roderick T, Vander Heiden, Matthew G
Published in BMC cancer (22.07.2019)
Published in BMC cancer (22.07.2019)
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Journal Article
PKM2 is not required for pancreatic ductal adenocarcinoma
Hillis, Alissandra L, Lau, Allison N, Devoe, Camille X, Dayton, Talya L, Danai, Laura V, Di Vizio, Dolores, Vander Heiden, Matthew G
Published in Cancer & metabolism (23.10.2018)
Published in Cancer & metabolism (23.10.2018)
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Journal Article
Low glycaemic diets alter lipid metabolism to influence tumour growth
Lien, Evan C., Westermark, Anna M., Zhang, Yin, Yuan, Chen, Li, Zhaoqi, Lau, Allison N., Sapp, Kiera M., Wolpin, Brian M., Vander Heiden, Matthew G.
Published in Nature (London) (11.11.2021)
Published in Nature (London) (11.11.2021)
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Journal Article
PKM2 is not required for colon cancer initiated by APC loss
Lau, Allison N, Israelsen, William J, Roper, Jatin, Sinnamon, Mark J, Georgeon, Larissa, Dayton, Talya L, Hillis, Alissandra L, Yilmaz, Omer H, Di Vizio, Dolores, Hung, Kenneth E, Vander Heiden, Matthew G
Published in Cancer & metabolism (30.11.2017)
Published in Cancer & metabolism (30.11.2017)
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Journal Article
Aspartate is an endogenous metabolic limitation for tumour growth
Sullivan, Lucas B., Luengo, Alba, Danai, Laura V., Bush, Lauren N., Diehl, Frances F., Hosios, Aaron M., Lau, Allison N., Elmiligy, Sarah, Malstrom, Scott, Lewis, Caroline A., Vander Heiden, Matthew G.
Published in Nature cell biology (01.07.2018)
Published in Nature cell biology (01.07.2018)
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Journal Article
Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers
Mayers, Jared R., Torrence, Margaret E., Danai, Laura V., Papagiannakopoulos, Thales, Davidson, Shawn M., Bauer, Matthew R., Lau, Allison N., Ji, Brian W., Dixit, Purushottam D., Hosios, Aaron M., Muir, Alexander, Chin, Christopher R., Freinkman, Elizaveta, Jacks, Tyler, Wolpin, Brian M., Vitkup, Dennis, Vander Heiden, Matthew G.
Published in Science (American Association for the Advancement of Science) (09.09.2016)
Published in Science (American Association for the Advancement of Science) (09.09.2016)
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Journal Article
Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance
Dalin, Simona, Sullivan, Mark R, Lau, Allison N, Grauman-Boss, Beatrice, Mueller, Helen S, Kreidl, Emanuel, Fenoglio, Silvia, Luengo, Alba, Lees, Jacqueline A, Vander Heiden, Matthew G, Lauffenburger, Douglas A, Hemann, Michael T
Published in Cancer research (Chicago, Ill.) (15.11.2019)
Published in Cancer research (Chicago, Ill.) (15.11.2019)
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Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis
Lau, Allison N, Curtis, Stephen J, Fillmore, Christine M, Rowbotham, Samuel P, Mohseni, Morvarid, Wagner, Darcy E, Beede, Alexander M, Montoro, Daniel T, Sinkevicius, Kerstin W, Walton, Zandra E, Barrios, Juliana, Weiss, Daniel J, Camargo, Fernando D, Wong, Kwok-Kin, Kim, Carla F
Published in The EMBO journal (01.07.2014)
Published in The EMBO journal (01.07.2014)
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Journal Article
Altered exocrine function can drive adipose wasting in early pancreatic cancer
Danai, Laura V., Babic, Ana, Rosenthal, Michael H., Dennstedt, Emily A., Muir, Alexander, Lien, Evan C., Mayers, Jared R., Tai, Karen, Lau, Allison N., Jones-Sali, Paul, Prado, Carla M., Petersen, Gloria M., Takahashi, Naoki, Sugimoto, Motokazu, Yeh, Jen Jen, Lopez, Nicole, Bardeesy, Nabeel, Fernandez-del Castillo, Carlos, Liss, Andrew S., Koong, Albert C., Bui, Justin, Yuan, Chen, Welch, Marisa W., Brais, Lauren K., Kulke, Matthew H., Dennis, Courtney, Clish, Clary B., Wolpin, Brian M., Vander Heiden, Matthew G.
Published in Nature (London) (01.06.2018)
Published in Nature (London) (01.06.2018)
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