Effective Targeting of Multiple B-Cell Maturation Antigen-Expressing Hematological Malignances by Anti-B-Cell Maturation Antigen Chimeric Antigen Receptor T Cells
Friedman, Kevin M, Garrett, Tracy E, Evans, John W, Horton, Holly M, Latimer, Howard J, Seidel, Stacie L, Horvath, Christopher J, Morgan, Richard A
Published in Human gene therapy (01.05.2018)
Published in Human gene therapy (01.05.2018)
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Abstract 48: T cell-specific in vivo transduction with preclinical candidate KLN-1010 generates BCMA directed CAR T cells with potent anti-multiple myeloma activity
Beura, Emily T., Latimer, Howard J., Wong, Denise, Obrigewitch, Jenifer, Warr, Alyson J., Dong, Shirley, Ariel, Matty, Figueroa, Josue, Figueroa, Joseph, Dobson, Connor S., Janaka, Sanath K., Najibi, Alexander J., Lau, Maggie, Contrastano, Shannon, Friedman, Kevin
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract 2296: Inhibition of the PI3K/Akt pathway during CAR T cell production results in enhanced efficacy across multiple in vivo tumor models
Grande, Shannon, Perkins, Molly R., Hamel, Amanda, Horton, Holly M., Eng, Fay, Rhodes, Claire J., Garrett, Tracy E., Miller, Sara M., Evans, John W., Latimer, Howard J., Horvath, Christopher, Kuczewski, Michael, Friedman, Kevin, Morgan, Richard A.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 2296: Inhibition of the PI3KAkt pathway during CAR T cell production results in enhanced efficacy across multiple in vivo tumor models
Grande, Shannon, Perkins, Molly R, Hamel, Amanda, Horton, Holly M, Eng, Fay, Rhodes, Claire J, Garrett, Tracy E, Miller, Sara M, Evans, John W, Latimer, Howard J, Horvath, Christopher, Kuczewski, Michael, Friedman, Kevin, Morgan, Richard A
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Manufacturing an Enhanced CAR T Cell Product By Inhibition of the PI3K/Akt Pathway During T Cell Expansion Results in Improved In Vivo Efficacy of Anti-BCMA CAR T Cells
Perkins, Molly R., Grande, Shannon, Hamel, Amanda, Horton, Holly M., Garrett, Tracy E., Miller, Sara M., Latimer, Howard J., Horvath, Christopher J., Kuczewski, Michael, Friedman, Kevin M., Morgan, Richard A.
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Characterization of Lentiviral Vector Derived Anti-Bcma CAR T Cells Reveals Key Parameters for Robust Manufacturing of Cell-Based Gene Therapies for Multiple Myeloma
Lilley, Graham, Ladd, Alden, Cossette, Daniel, Viggiano, Laura, Hopkins, Gregory, Evans, John W., Li, Mingli, Latimer, Howard J., Miller, Sara M., Kuczewski, Michael, Bakeman, Wendy, MacLeod, Kayla, Friedman, Kevin M., Maier, Dawn A, Paglia, Michael, Morgan, Richard A., Angelino, Mark D
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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A Novel and Highly Potent CAR T Cell Drug Product for Treatment of BCMA-Expressing Hematological Malignances
Chekmasova, Alena A., Horton, Holly M., Garrett, Tracy E., Evans, John W., Griecci, Johanna, Hamel, Amanda, Latimer, Howard J., Seidel, Stacie L., Ryu, Byoung Y., Kuczewski, Michael, Horvath, Christopher J., Friedman, Kevin M., Morgan, Richard A.
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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A BCMA-specific CAR T cell produced with clinically scalable lentiviral and T cell manufacturing processes has potent anti-multiple myeloma activity
Garrett, Tracy E, Chekmasova, Alena A, Evans, John W, Seidel, Stacie L, Horton, Holly M, Latimer, Howard J, Griecci, Johanna A, Horvath, Christopher J, Ryu, Byoung Y, Friedman, Kevin M, Morgan, Richard A
Published in Journal for immunotherapy of cancer (04.11.2015)
Published in Journal for immunotherapy of cancer (04.11.2015)
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