Hydroxyurea to lower transcranial Doppler velocities and prevent primary stroke: the Uganda NOHARM sickle cell anemia cohort
Opoka, Robert O, Hume, Heather A, Latham, Teresa S, Lane, Adam, Williams, Olatundun, Tymon, Jennifer, Nakafeero, Maria, Kasirye, Phillip, Ndugwa, Christopher M, John, Chandy C, Ware, Russell E
Published in Haematologica (Roma) (01.06.2020)
Published in Haematologica (Roma) (01.06.2020)
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Prospective identification of variables as outcomes for treatment (PIVOT): study protocol for a randomised, placebo-controlled trial of hydroxyurea for Ghanaian children and adults with haemoglobin SC disease
Smart, Luke R, Segbefia, Catherine I, Latham, Teresa S, Stuber, Susan E, Amissah-Arthur, Kwesi N, Dzefi-Tettey, Klenam, Lane, Adam C, Dei-Adomakoh, Yvonne A, Ware, Russell E
Published in Current controlled trials in cardiovascular medicine (22.09.2023)
Published in Current controlled trials in cardiovascular medicine (22.09.2023)
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Journal Article
Stroke Prevention with Hydroxyurea Enabled through Research and Education: A Phase 2 Primary Stroke Prevention Trial in Sub-Saharan Africa
Smart, Luke R, Ambrose, Emmanuela E, Balyorugulu, Georgina, Songoro, Primrose, Shabani, Idd, Komba, Protas, Charles, Mwesige, Howard, Thad A, McElhinney, Kathryn E, O'Hara, Sara M, Odame, Jodie, Nakafeero, Maria, Adams, Janet, Stuber, Susan E, Lane, Adam, Latham, Teresa S, Makubi, Abel N, Ware, Russell E
Published in Acta haematologica (2023)
Published in Acta haematologica (2023)
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Journal Article
Hydroxyurea Optimization through Precision Study (HOPS): study protocol for a randomized, multicenter trial in children with sickle cell anemia
Meier, Emily R, Creary, Susan E, Heeney, Matthew M, Dong, Min, Appiah-Kubi, Abena O, Nelson, Stephen C, Niss, Omar, Piccone, Connie, Quarmyne, Maa-Ohui, Quinn, Charles T, Saving, Kay L, Scott, John P, Talati, Ravi, Latham, Teresa S, Pfeiffer, Amanda, Shook, Lisa M, Vinks, Alexander A, Lane, Adam, McGann, Patrick T
Published in Current controlled trials in cardiovascular medicine (27.11.2020)
Published in Current controlled trials in cardiovascular medicine (27.11.2020)
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Journal Article
Hydroxyurea Dose Escalation for Sickle Cell Anemia in Sub-Saharan Africa
John, Chandy C, Opoka, Robert O, Latham, Teresa S, Hume, Heather A, Nabaggala, Catherine, Kasirye, Phillip, Ndugwa, Christopher M, Lane, Adam, Ware, Russell E
Published in The New England journal of medicine (25.06.2020)
Published in The New England journal of medicine (25.06.2020)
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Journal Article
Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia
Opoka, Robert O., Ndugwa, Christopher M., Latham, Teresa S., Lane, Adam, Hume, Heather A., Kasirye, Phillip, Hodges, James S., Ware, Russell E., John, Chandy C.
Published in Blood (14.12.2017)
Published in Blood (14.12.2017)
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Journal Article
Hydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa
Tshilolo, Léon, Tomlinson, George, Williams, Thomas N, Santos, Brígida, Olupot-Olupot, Peter, Lane, Adam, Aygun, Banu, Stuber, Susan E, Latham, Teresa S, McGann, Patrick T, Ware, Russell E
Published in The New England journal of medicine (10.01.2019)
Published in The New England journal of medicine (10.01.2019)
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Journal Article
Hydroxyurea treatment is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa
Olupot-Olupot, Peter, Tomlinson, George, Williams, Thomas N., Tshilolo, Léon, Santos, Brígida, Smart, Luke R., McElhinney, Kathryn, Howard, Thad A., Aygun, Banu, Stuber, Susan E., Lane, Adam, Latham, Teresa S., Ware, Russell E.
Published in Blood (23.03.2023)
Published in Blood (23.03.2023)
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Journal Article
Pharmacokinetic-guided hydroxyurea to reduce transfusions in Ugandan children with sickle cell anemia: study design of the Alternative Dosing And Prevention of Transfusions (ADAPT) trial
Power-Hays, Alexandra, Namazzi, Ruth, Kato, Charles, McElhinney, Kathryn E, Conroy, Andrea L, Hume, Heather, John, Chandy, O'Hara, Sara M, Stuber, Susan E, Lane, Adam, Latham, Teresa S, Opoka, Robert O, Ware, Russell E
Published in Acta haematologica (05.06.2024)
Published in Acta haematologica (05.06.2024)
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Journal Article
Hydroxyurea with dose escalation for primary stroke risk reduction in children with sickle cell anaemia in Tanzania (SPHERE): an open-label, phase 2 trial
Ambrose, Emmanuela E, Latham, Teresa S, Songoro, Primrose, Charles, Mwesige, Lane, Adam C, Stuber, Susan E, Makubi, Abel N, Ware, Russell E, Smart, Luke R
Published in The Lancet. Haematology (01.04.2023)
Published in The Lancet. Haematology (01.04.2023)
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Journal Article
Stroke Avoidance for Children in REpública Dominicana (SACRED): Protocol for a Prospective Study of Stroke Risk and Hydroxyurea Treatment in Sickle Cell Anemia
Jeste, Neelum D, Sánchez, Luisanna M, Urcuyo, Gabriela S, Bergés, Melissa E, Luden, Judy P, Stuber, Susan E, Latham, Teresa S, Mena, Rafael, Nieves, Rosa M, Ware, Russell E
Published in JMIR research protocols (02.06.2017)
Published in JMIR research protocols (02.06.2017)
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Journal Article
Effects of L-Glutamine on Biomarkers of Response in Sickle Cell Disease: A Pharmacokinetics-Pharmacodynamics Analysis
Sadaf, Alina, Dong, Min, Korpik, Jennifer, Pfeiffer, Amanda, Kalfa, Theodosia A., Latham, Teresa S., Vinks, Alexander A., Ware, Russell E., Quinn, Charles T.
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Hydroxyurea Improves Intelligence Quotient Scores in Children with Sickle Cell Anemia and Elevated Transcranial Doppler Velocity
Rankine-Mullings, Angela E, Soares, Deanne, Aldred, Karen, Chang-Lopez, Susan, Wisdom-Phipps, Margaret Elizabeth, Schultz, William, Latham, Teresa S., Stuber, Susan E., Jackson, Patrice, Ware, Russell E., Reid, Marvin Ellsworth
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Pharmacokinetic-Guided Hydroxyurea to Reduce Transfusion Requirements in Ugandan Children with Sickle Cell Anemia: Baseline Data from the Alternative Dosing and Prevention of Transfusions (ADAPT) Trial
Power-Hays, Alexandra, Namazzi, Ruth, Kato, Charles, Conroy, Andrea, Hume, Heather Ann, John, Chandy C., Stuber, Susan E., Lane, Adam C., Latham, Teresa S., Opoka, Robert, Ware, Russell E.
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Prospective Identification of Variables As Outcomes for Treatment (PIVOT): A Phase II Clinical Trial of Hydroxyurea for Children and Adults with HbSC Disease
Segbefia, Catherine I., Smart, Luke R., Stuber, Susan E., Ekpale, Priscilla, Amissah-Arthur, Kwesi N., Dzefi-Tettey, Klenam, Mensah, Enoch, Lane, Adam C., Dwuma-Badu, Diana, Latham, Teresa S., Dei-Adomakoh, Yvonne, Ware, Russell E.
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Hydroxyurea Dose Optimization Is Safe and Improves Outcomes for Children with Sickle Cell Anemia Living in Sub-Saharan Africa: The Reach Experience
Aygun, Banu, Lane, Adam C., Smart, Luke R., Tshilolo, Leon, Williams, Thomas N., Olupot-Olupot, Peter, Santos, Brigida, Stuber, Susan E., Tomlinson, George A., Latham, Teresa S., Ware, Russell E.
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Effects of Hydroxyurea Treatment on Malaria Infections in Sub-Saharan Africa
Olupot-Olupot, Peter, Tomlinson, George A., Latham, Teresa S., McGann, Patrick T., Santos, Brigida, Aygun, Banu, Stuber, Susan, Tshilolo, Leon, Lane, Adam, Williams, Thomas N., Ware, Russell E.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Genetic Analysis in the Tanzania Sickle Surveillance Study (TS3): Modifiers of Sickle Cell Disease and Identification of Hemoglobin Variants
Smart, Luke R., Ambrose, Emmanuela E., Charles, Mwesige, Hernandez, Arielle G., Latham, Teresa S., Hokororo, Adolfine, Beyanga, Medard, Kamugisha, Erasmus, Tebuka, Erius, Howard, Thad A., Ware, Russell E.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Splenomegaly in Children with Sickle Cell Anemia Receiving Hydroxyurea in Sub-Saharan Africa
Tshilolo, Leon, Tomlinson, George A., McGann, Patrick T., Latham, Teresa S., Olupot-Olupot, Peter, Santos, Brigida, Aygun, Banu, Stuber, Susan, Lane, Adam, Williams, Thomas N., Ware, Russell E.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Stroke Avoidance for Children in República Dominicana (SACRED):a Prospective Trial to Reduce Stroke in Children with Sickle Cell Anemia
Sanchez, Luisanna, Nieves, Rosa M., Latham, Teresa S., Lane, Adam, Jeste, Neelum, Urcuyo, Gabriela S., Berges, Melissa E., Florencio, Carla, Gonzalez, Carla, Del Villar, Paola, Adams, Janet, Stuber, Susan, Schultz, William, Mena, Rafael, Ware, Russell E.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article