Precision oncology: a clinical and patient perspective
Lassen, Ulrik N, Makaroff, Lydia E, Stenzinger, Albrecht, Italiano, Antoine, Vassal, Gilles, Garcia-Foncillas, Jesus, Avouac, Bernard
Published in Future oncology (London, England) (01.10.2021)
Published in Future oncology (London, England) (01.10.2021)
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Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children
Drilon, Alexander, Laetsch, Theodore W, Kummar, Shivaani, DuBois, Steven G, Lassen, Ulrik N, Demetri, George D, Nathenson, Michael, Doebele, Robert C, Farago, Anna F, Pappo, Alberto S, Turpin, Brian, Dowlati, Afshin, Brose, Marcia S, Mascarenhas, Leo, Federman, Noah, Berlin, Jordan, El-Deiry, Wafik S, Baik, Christina, Deeken, John, Boni, Valentina, Nagasubramanian, Ramamoorthy, Taylor, Matthew, Rudzinski, Erin R, Meric-Bernstam, Funda, Sohal, Davendra P.S, Ma, Patrick C, Raez, Luis E, Hechtman, Jaclyn F, Benayed, Ryma, Ladanyi, Marc, Tuch, Brian B, Ebata, Kevin, Cruickshank, Scott, Ku, Nora C, Cox, Michael C, Hawkins, Douglas S, Hong, David S, Hyman, David M
Published in The New England journal of medicine (22.02.2018)
Published in The New England journal of medicine (22.02.2018)
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Journal Article
A systematic review of targeted agents for non-small cell lung cancer
Vestergaard, Hannah H., Christensen, Marcus R., Lassen, Ulrik N.
Published in Acta oncologica (01.02.2018)
Published in Acta oncologica (01.02.2018)
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Journal Article
Targeting CD38 with Daratumumab Monotherapy in Multiple Myeloma
Lokhorst, Henk M, Plesner, Torben, Laubach, Jacob P, Nahi, Hareth, Gimsing, Peter, Hansson, Markus, Minnema, Monique C, Lassen, Ulrik, Krejcik, Jakub, Palumbo, Antonio, van de Donk, Niels W.C.J, Ahmadi, Tahamtan, Khan, Imran, Uhlar, Clarissa M, Wang, Jianping, Sasser, A. Kate, Losic, Nedjad, Lisby, Steen, Basse, Linda, Brun, Nikolai, Richardson, Paul G
Published in The New England journal of medicine (24.09.2015)
Published in The New England journal of medicine (24.09.2015)
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Journal Article
Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer
Jacobsen, Kirstine, Bertran-Alamillo, Jordi, Molina, Miguel Angel, Teixidó, Cristina, Karachaliou, Niki, Pedersen, Martin Haar, Castellví, Josep, Garzón, Mónica, Codony-Servat, Carles, Codony-Servat, Jordi, Giménez-Capitán, Ana, Drozdowskyj, Ana, Viteri, Santiago, Larsen, Martin R., Lassen, Ulrik, Felip, Enriqueta, Bivona, Trever G., Ditzel, Henrik J., Rosell, Rafael
Published in Nature communications (04.09.2017)
Published in Nature communications (04.09.2017)
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Journal Article
Rationale and design of ON-TRK: a novel prospective non-interventional study in patients with TRK fusion cancer treated with larotrectinib
Yang, James C H, Brose, Marcia S, Castro, Gilberto, Kim, Edward S, Lassen, Ulrik N, Leyvraz, Serge, Pappo, Alberto, López-Ríos, Fernando, Reeves, John A, Fellous, Marc, Penault-Llorca, Frédérique, Rudzinski, Erin R, Tabatabai, Ghazaleh, Vassal, Gilles, Drilon, Alexander, Trent, Jonathan
Published in BMC cancer (07.06.2022)
Published in BMC cancer (07.06.2022)
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Journal Article
Criteria for site selection in industry-sponsored clinical trials: a survey among decision-makers in biopharmaceutical companies and clinical research organizations
Dombernowsky, Tilde, Haedersdal, Merete, Lassen, Ulrik, Thomsen, Simon Francis
Published in Current controlled trials in cardiovascular medicine (11.12.2019)
Published in Current controlled trials in cardiovascular medicine (11.12.2019)
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Journal Article
Testing NTRK testing: Wet‐lab and in silico comparison of RNA‐based targeted sequencing assays
Pfarr, Nicole, Kirchner, Martina, Lehmann, Ulrich, Leichsenring, Jonas, Merkelbach‐Bruse, Sabine, Glade, Julia, Hummel, Michael, Stögbauer, Fabian, Lehmann, Annika, Trautmann, Marcel, Kumbrink, Jörg, Jung, Andreas, Dietmaier, Wolfgang, Endris, Volker, Kazdal, Daniel, Evert, Matthias, Horst, David, Kreipe, Hans, Kirchner, Thomas, Wardelmann, Eva, Lassen, Ulrik, Büttner, Reinhard, Weichert, Wilko, Dietel, Manfred, Schirmacher, Peter, Stenzinger, Albrecht
Published in Genes chromosomes & cancer (01.03.2020)
Published in Genes chromosomes & cancer (01.03.2020)
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Journal Article
Phase 1/2 study of daratumumab, lenalidomide, and dexamethasone for relapsed multiple myeloma
Plesner, Torben, Arkenau, Hendrik-Tobias, Gimsing, Peter, Krejcik, Jakub, Lemech, Charlotte, Minnema, Monique C., Lassen, Ulrik, Laubach, Jacob P., Palumbo, Antonio, Lisby, Steen, Basse, Linda, Wang, Jianping, Sasser, A. Kate, Guckert, Mary E., de Boer, Carla, Khokhar, Nushmia Z., Yeh, Howard, Clemens, Pamela L., Ahmadi, Tahamtan, Lokhorst, Henk M., Richardson, Paul G.
Published in Blood (06.10.2016)
Published in Blood (06.10.2016)
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Journal Article
Changes in key recruitment performance metrics from 2008–2019 in industry-sponsored phase III clinical trials registered at ClinicalTrials.gov
Brøgger-Mikkelsen, Mette, Zibert, John Robert, Andersen, Anders Daniel, Lassen, Ulrik, Hædersdal, Merete, Ali, Zarqa, Thomsen, Simon Francis
Published in PloS one (26.07.2022)
Published in PloS one (26.07.2022)
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Journal Article
Total burden of disease in cancer patients at diagnosis—a Danish nationwide study of multimorbidity and redeemed medication
Loeppenthin, Katrine, Dalton, Susanne Oksbjerg, Johansen, Christoffer, Andersen, Elisabeth, Christensen, Mikkel Bring, Pappot, Helle, Petersen, Lone Nørgaard, Thisted, Lise Bjerrum, Frølich, Anne, Mortensen, Christiane Ehlers, Lassen, Ulrik, Ørsted, Jytte, Bidstrup, Pernille Envold
Published in British journal of cancer (15.09.2020)
Published in British journal of cancer (15.09.2020)
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Journal Article
VEGF-C sustains VEGFR2 activation under bevacizumab therapy and promotes glioblastoma maintenance
Michaelsen, Signe R, Staberg, Mikkel, Pedersen, Henriette, Jensen, Kamilla E, Majewski, Wiktor, Broholm, Helle, Nedergaard, Mette K, Meulengracht, Christopher, Urup, Thomas, Villingshøj, Mette, Lukacova, Slávka, Skjøth-Rasmussen, Jane, Brennum, Jannick, Kjær, Andreas, Lassen, Ulrik, Stockhausen, Marie-Thérése, Poulsen, Hans S, Hamerlik, Petra
Published in Neuro-oncology (Charlottesville, Va.) (09.10.2018)
Published in Neuro-oncology (Charlottesville, Va.) (09.10.2018)
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Journal Article
Larotrectinib efficacy and safety in adult patients with tropomyosin receptor kinase fusion sarcomas
Kummar, Shivaani, Shen, Lin, Hong, David S, McDermott, Ray, Keedy, Vicki L, Casanova, Michela, Demetri, George D, Dowlati, Afshin, Melcón, Soledad Gallego, Lassen, Ulrik N, Leyvraz, Serge, Liu, Tianshu, Moreno, Victor, Patel, Jyoti, Patil, Tejas, Mallick, Atrayee Basu, Sousa, Nuno, Tahara, Makoto, Ziegler, David S, Norenberg, Ricarda, Arvis, Pierre, Brega, Nicoletta, Drilon, Alexander, Tan, Daniel S W
Published in Cancer (01.12.2023)
Published in Cancer (01.12.2023)
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Journal Article
Glioblastoma cells increase expression of notch signaling and synaptic genes within infiltrated brain tissue
Harwood, Dylan Scott Lykke, Pedersen, Vilde, Bager, Nicolai Schou, Schmidt, Ane Yde, Stannius, Tobias Overlund, Areškevičiūtė, Aušrinė, Josefsen, Knud, Nørøxe, Dorte Schou, Scheie, David, Rostalski, Hannah, Lü, Maya Jeje Schuang, Locallo, Alessio, Lassen, Ulrik, Bagger, Frederik Otzen, Weischenfeldt, Joachim, Heiland, Dieter Henrik, Vitting-Seerup, Kristoffer, Michaelsen, Signe Regner, Kristensen, Bjarne Winther
Published in Nature communications (09.09.2024)
Published in Nature communications (09.09.2024)
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Molecular profiling of short-term and long-term surviving patients identifies CD34 mRNA level as prognostic for glioblastoma survival
Michaelsen, Signe Regner, Urup, Thomas, Olsen, Lars Rønn, Broholm, Helle, Lassen, Ulrik, Poulsen, Hans Skovgaard
Published in Journal of neuro-oncology (01.05.2018)
Published in Journal of neuro-oncology (01.05.2018)
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Journal Article
Efficacy and Safety of Larotrectinib in Patients With Tropomyosin Receptor Kinase Fusion-Positive Lung Cancers
Drilon, Alexander, Tan, Daniel S W, Lassen, Ulrik N, Leyvraz, Serge, Liu, Yongmei, Patel, Jyoti D, Rosen, Lee, Solomon, Benjamin, Norenberg, Ricarda, Dima, Laura, Brega, Nicoletta, Shen, Lin, Moreno, Victor, Kummar, Shivaani, Lin, Jessica J
Published in JCO precision oncology (01.01.2022)
Published in JCO precision oncology (01.01.2022)
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First-in-Human Phase I Study of Lumretuzumab, a Glycoengineered Humanized Anti-HER3 Monoclonal Antibody, in Patients with Metastatic or Advanced HER3-Positive Solid Tumors
Meulendijks, Didier, Jacob, Wolfgang, Martinez-Garcia, Maria, Taus, Alvaro, Lolkema, Martijn P, Voest, Emile E, Langenberg, Marlies H G, Fleitas Kanonnikoff, Tania, Cervantes, Andres, De Jonge, Maja J, Sleijfer, Stefan, Soerensen, Morten Mau, Thomas, Marlene, Ceppi, Maurizio, Meneses-Lorente, Georgina, James, Ian, Adessi, Celine, Michielin, Francesca, Abiraj, Keelara, Bossenmaier, Birgit, Schellens, Jan H M, Weisser, Martin, Lassen, Ulrik N
Published in Clinical cancer research (15.02.2016)
Published in Clinical cancer research (15.02.2016)
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