Injectable Biodegradable Silica Depot: Two Months of Sustained Release of the Blood Glucose Lowering Peptide, Pramlintide
Tyagi, Puneet, Koskinen, Mika, Mikkola, Jari, Sarkhel, Sanjay, Leino, Lasse, Seth, Asha, Madalli, Shimona, Will, Sarah, Howard, Victor G, Brant, Helen, Corkill, Dominic
Published in Pharmaceutics (02.03.2022)
Published in Pharmaceutics (02.03.2022)
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Journal Article
Sustained In-Vivo Release of Triptorelin Acetate from a Biodegradable Silica Depot: Comparison to Pamorelin® LA
Forsback, Ari-Pekka, Noppari, Panu, Viljanen, Jesse, Mikkola, Jari, Jokinen, Mika, Leino, Lasse, Bjerregaard, Simon, Borglin, Camilla, Halliday, Janet
Published in Nanomaterials (Basel, Switzerland) (16.06.2021)
Published in Nanomaterials (Basel, Switzerland) (16.06.2021)
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Journal Article
Protodynamic Intracellular Acidification by cis-Urocanic Acid Promotes Apoptosis of Melanoma Cells In Vitro and In Vivo
Laihia, Jarmo K., Kallio, Janne P., Taimen, Pekka, Kujari, Harry, Kähäri, Veli-Matti, Leino, Lasse
Published in Journal of investigative dermatology (01.10.2010)
Published in Journal of investigative dermatology (01.10.2010)
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Journal Article
Molecular targets for the protodynamic action of cis-urocanic acid in human bladder carcinoma cells
Peuhu, Emilia, Kaunisto, Aura, Laihia, Jarmo K, Leino, Lasse, Eriksson, John E
Published in BMC cancer (03.10.2010)
Published in BMC cancer (03.10.2010)
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Journal Article
Clinical phase 1 safety and tolerability evaluation of sustained release silica composite eye drops in human subjects
Kaarniranta, Kai, Reay, Marcus, Leino, Lasse, Kievari, Sari, Hartikainen, Arto, Martikainen, Oona, Kemiläinen, Benjam
Published in Acta ophthalmologica (Oxford, England) (01.01.2024)
Published in Acta ophthalmologica (Oxford, England) (01.01.2024)
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Journal Article
Tolerability of silica microparticle gels as drug delivery vehicles
Poluianova, Aleksandra, Robciuc, Alexandra, Moilanen, Jukka, Kaarniranta, Kai, Leino, Lasse, Pollari, Ville, Dargelas, Frederic, Reay, Marcus
Published in Acta ophthalmologica (Oxford, England) (01.01.2024)
Published in Acta ophthalmologica (Oxford, England) (01.01.2024)
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Journal Article
Development of injectable long‐acting controlled release intravitreal depot of BAY224 using biodegradable silica microparticle‐silica hydrogel composite
Dargelas, Frederic, Forsback, Aripekka, Mattila, Aarne, Leino, Lasse, Noppari, Panu, Reay, Marcus, Terjung, Carsten, Unger, Florian, Baerfacker, Lars
Published in Acta ophthalmologica (Oxford, England) (01.01.2021)
Published in Acta ophthalmologica (Oxford, England) (01.01.2021)
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Journal Article
Silica microparticles for sustained zero-order release of an anti-CD40L antibody
Tyagi, Puneet, Koskinen, Mika, Mikkola, Jari, Leino, Lasse, Schwarz, Alexander
Published in Drug delivery and translational research (01.04.2018)
Published in Drug delivery and translational research (01.04.2018)
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Journal Article
Injectable Biodegradable Silica Depot for Controlled Subcutaneous Delivery of Antisense Oligonucleotides with beyond Monthly Administration
McGowan, Asmaa, Gennemark, Peter, Akieh-Pirkanniemi, Marceline, Wirman, Linda, Davies, Nigel, Elebring, Marie, Tivesten, Anna, Strimfors, Marie, Hölttä, Mikko, Söderberg, Magnus, Berntsson, Veronica, Balas, Daniela, Koskinen, Mika, Leino, Lasse, Abrahmsén-Alami, Susanna
Published in Molecular pharmaceutics (01.01.2024)
Published in Molecular pharmaceutics (01.01.2024)
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Journal Article
Topical cis-urocanic acid prevents ocular surface irritation in both IgE -independent and -mediated rat model
Jauhonen, Hanna-Mari, Laihia, Jarmo, Oksala, Olli, Viiri, Johanna, Sironen, Reijo, Alajuuma, Päivi, Kaarniranta, Kai, Leino, Lasse
Published in Graefe's archive for clinical and experimental ophthalmology (01.12.2017)
Published in Graefe's archive for clinical and experimental ophthalmology (01.12.2017)
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Journal Article
Intravesical treatment with cis-urocanic acid improves bladder function in rat model of acute bladder inflammation: Cis -Urocanic Acid for Intravesical Treatment
Konkol, Yvonne, Bernoulli, Jenni, Streng, Tomi, Jääskeläinen, Katarina, Laihia, Jarmo, Leino, Lasse
Published in Neurourology and urodynamics (01.09.2016)
Published in Neurourology and urodynamics (01.09.2016)
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Journal Article
A randomized phase I clinical study of cis‐urocanic acid eye drops in healthy adult subjects
Jauhonen, Hanna‐Mari, Kari, Eeva, Pylkkänen, Liisa, Poutanen, Jutta, Laihia, Jarmo, Kaarniranta, Kai, Leino, Lasse
Published in Acta ophthalmologica (Oxford, England) (01.06.2015)
Published in Acta ophthalmologica (Oxford, England) (01.06.2015)
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Journal Article
Three randomised phase I/IIa trials of 5% cis-urocanic acid emulsion cream in healthy adult subjects and in patients with atopic dermatitis
Peltonen, Juha M, Pylkkänen, Liisa, Jansén, Christer T, Volanen, Iina, Lehtinen, Terhi, Laihia, Jarmo K, Leino, Lasse
Published in Acta dermato-venereologica (01.01.2014)
Published in Acta dermato-venereologica (01.01.2014)
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Journal Article
Antitumor Effects of cis -Urocanic Acid on Experimental Urothelial Cell Carcinoma of the Bladder
Arentsen, Harm C, Jansen, Cornelius F.J, Hulsbergen-van de Kaa, Christina A, Laihia, Jarmo K, Pylkkänen, Liisa, Leino, Lasse, Oosterwijk, Egbert, Witjes, J. Alfred
Published in The Journal of urology (01.04.2012)
Published in The Journal of urology (01.04.2012)
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Journal Article
Protodynamic therapy for bladder cancer: in vitro results of a novel treatment concept
Laihia, Jarmo K., Pylkkänen, Liisa, Laato, Matti, Boström, Peter J., Leino, Lasse
Published in BJU international (01.11.2009)
Published in BJU international (01.11.2009)
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Journal Article
Determination of the Dissociation Constants of Urocanic Acid Isomers in Aqueous Solutions
Juusola, Pekka, Minkkinen, Pentti, Leino, Lasse, Laihia, Jarmo K.
Published in Monatshefte für Chemie (01.10.2007)
Published in Monatshefte für Chemie (01.10.2007)
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Journal Article
Effects of intramammary infusion of cis-urocanic acid on mastitis-associated inflammation and tissue injury in dairy cows
Bannerman, Douglas D, Rinaldi, Manuela, Vinyard, Bryan T, Laihia, Jarmo, Leino, Lasse
Published in American journal of veterinary research (01.03.2009)
Published in American journal of veterinary research (01.03.2009)
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