Absorption, metabolism and excretion of 14C-emvododstat following repeat daily oral dose administration in human volunteers using a combination of microtracer radioactivity and high radioactivity doses
Ma, Jiyuan, Laskin, Oscar L, Roffel, Ad F, Vaes, Wouter H J, Tang, Bowen, Kolnaar, Jeroen, O'Keefe, Kylie, Golden, Lee, Kong, Ronald
Published in Drug metabolism and disposition (01.01.2024)
Published in Drug metabolism and disposition (01.01.2024)
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Journal Article
Preclinical and Early Clinical Development of PTC596, a Novel Small-Molecule Tubulin-Binding Agent
Jernigan, Finith, Branstrom, Arthur, Baird, John D, Cao, Liangxian, Dali, Mandar, Furia, Bansri, Kim, Min Jung, O'Keefe, Kylie, Kong, Ronald, Laskin, Oscar L, Colacino, Joseph M, Pykett, Mark, Mollin, Anna, Sheedy, Josephine, Dumble, Melissa, Moon, Young-Choon, Sheridan, Richard, Mühlethaler, Tobias, Spiegel, Robert J, Prota, Andrea E, Steinmetz, Michel O, Weetall, Marla
Published in Molecular cancer therapeutics (01.10.2021)
Published in Molecular cancer therapeutics (01.10.2021)
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Journal Article
A clinical pharmacokinetic drug-drug interaction study between dextromethorphan and emvododstat, a potent anti-SARS-CoV-2 dihydroorotate dehydrogenase inhibitor
Morton, Terri L., Laskin, Oscar L., Kaushik, Diksha, Lee, Lucy, Ma, Jiyuan, Bar, Cristian M., Kristensen, Allan, O’Keefe, Kylie, Golden, Lee, Klein, Matthew, Kong, Ronald
Published in European journal of clinical pharmacology (01.08.2023)
Published in European journal of clinical pharmacology (01.08.2023)
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Journal Article
Pharmacokinetics of lenalidomide in subjects with various degrees of renal impairment and in subjects on hemodialysis
Chen, Nianhang, Lau, Henry, Kong, Linghui, Kumar, Gondi, Zeldis, Jerome B, Knight, Robert, Laskin, Oscar L
Published in Journal of clinical pharmacology (01.12.2007)
Published in Journal of clinical pharmacology (01.12.2007)
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A pharmacokinetic drug–drug interaction study between rosuvastatin and emvododstat, a potent anti‐SARS‐CoV‐2 (COVID‐19) DHODH (dihydroorotate dehydrogenase) inhibitor
Morton, Terri L., Laskin, Oscar L., Kaushik, Diksha, Lee, Lucy, Ma, Jiyuan, Kristensen, Allan, O'Keefe, Kylie, Golden, Lee, Klein, Matthew, Kong, Ronald
Published in Pharmacology research & perspectives (01.04.2023)
Published in Pharmacology research & perspectives (01.04.2023)
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Journal Article
Pharmacokinetics and Safety of PTC596, a Novel Tubulin‐Binding Agent, in Subjects With Advanced Solid Tumors
Shapiro, Geoffrey I., O'Mara, Edward, Laskin, Oscar L., Gao, Lan, Baird, John D., Spiegel, Robert J., Kaushik, Diksha, Weetall, Marla, Colacino, Joseph, O'Keefe, Kylie, Branstrom, Arthur, Goodwin, Elizabeth, Infante, Jeffrey, Bedard, Philippe L., Kong, Ronald
Published in Clinical pharmacology in drug development (01.08.2021)
Published in Clinical pharmacology in drug development (01.08.2021)
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Journal Article
Ataluren Pharmacokinetics in Healthy Japanese and Caucasian Subjects
Kong, Ronald, Laskin, Oscar L., Kaushik, Diksha, Jin, Fengbin, Ma, Jiyuan, McIntosh, Joseph, Souza, Marcio, Almstead, Neil
Published in Clinical pharmacology in drug development (01.02.2019)
Published in Clinical pharmacology in drug development (01.02.2019)
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Journal Article
Distribution of lenalidomide into semen of healthy men after multiple oral doses
Chen, Nianhang, Lau, Henry, Choudhury, Somesh, Wang, Xiaomin, Assaf, Mahmoud, Laskin, Oscar L
Published in Journal of clinical pharmacology (01.07.2010)
Published in Journal of clinical pharmacology (01.07.2010)
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Journal Article
Disposition, metabolism and mass balance of [14C]apremilast following oral administration
Hoffmann, Matthew, Kumar, Gondi, Schafer, Peter, Cedzik, Dorota, Capone, Lori, Fong, Kei-Lai, Gu, Zheming, Heller, Dennis, Feng, Hao, Surapaneni, Sekhar, Laskin, Oscar, Wu, Anfan
Published in Xenobiotica (01.12.2011)
Published in Xenobiotica (01.12.2011)
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Journal Article
Clinical pharmacokinetics of thalidomide
TEO, Steve K, COLBURN, Wayne A, TRACEWELL, William G, KOOK, Karin A, STIRLIN, David I, JAWORSKY, Markian S, SCHEFFLER, Michael A, THOMAS, Steve D, LASKIN, Oscar L
Published in Clinical pharmacokinetics (01.01.2004)
Published in Clinical pharmacokinetics (01.01.2004)
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Journal Article
Evaluation of the developmental toxicity of lenalidomide in rabbits
Christian, Mildred S., Laskin, Oscar L., Sharper, Valerie, Hoberman, Alan, Stirling, David I., Latriano, Louise
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.06.2007)
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.06.2007)
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Journal Article
The Efficacy of Azidothymidine (AZT) in the Treatment of Patients with AIDS and AIDS-Related Complex
Fischl, Margaret A, Richman, Douglas D, Grieco, Michael H, Gottlieb, Michael S, Volberding, Paul A, Laskin, Oscar L, Leedom, John M, Groopman, Jerome E, Mildvan, Donna, Schooley, Robert T, Jackson, George G, Durack, David T, King, Dannie
Published in The New England journal of medicine (23.07.1987)
Published in The New England journal of medicine (23.07.1987)
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Journal Article
Absorption, Metabolism, and Excretion of 14 C-Emvododstat Following Repeat Daily Oral Dose Administration in Human Volunteers Using a Combination of Microtracer Radioactivity and High-Radioactivity Doses
Ma, Jiyuan, Laskin, Oscar L., Roffel, Ad F., Vaes, Wouter H.J., Tang, Bowen, Kolnaar, Jeroen, O’Keefe, Kylie, Golden, Lee, Kong, Ronald
Published in Drug metabolism and disposition (01.01.2024)
Published in Drug metabolism and disposition (01.01.2024)
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Journal Article
A Short-Term Clinical Evaluation of L-697,661, a Non-Nucleoside Inhibitor of HIV-1 Reverse Transcriptase
Saag, Michael S, Emini, Emilio A, Laskin, Oscar L, Douglas, Jeffrey, Lapidus, William I, Schleif, William A, Whitley, Richard J, Hildebrand, Carol, Byrnes, Vera W, Kappes, John C, Anderson, Kevin W, Massari, Ferdinand E, Shaw, George M
Published in The New England journal of medicine (07.10.1993)
Published in The New England journal of medicine (07.10.1993)
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Journal Article
Phase 1 results of PTC596, a novel small molecule targeting cancer stem cells (CSCs) by reducing levels of BMI1 protein
Infante, Jeffrey R., Bedard, Philippe L., Shapiro, Geoffrey, Bauer, Todd Michael, Prawira, Amy, Laskin, Oscar, Weetall, Marla, Baird, John, Branstrom, Art, O'Mara, Edward, Spiegel, Robert J.
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Journal Article
Acyclovir Prophylaxis of Herpes-Simplex-Virus Infections: A Randomized, Double-Blind, Controlled Trial in Bone-Marrow-Transplant Recipients
Saral, Rein, Burns, William H, Laskin, Oscar L, Santos, George W, Lietman, Paul S
Published in The New England journal of medicine (09.07.1981)
Published in The New England journal of medicine (09.07.1981)
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Journal Article
Acyclovir Halts Progression of Herpes Zoster in Immunocompromised Patients
Balfour, Henry H, Bean, Bonnie, Laskin, Oscar L, Ambinder, Richard F, Meyers, Joel D, Wade, James C, Zaia, John A, Aeppli, Dorothee, Kirk, L. Edward, Segreti, Anthony C, Keeney, Ronald E
Published in The New England journal of medicine (16.06.1983)
Published in The New England journal of medicine (16.06.1983)
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Journal Article
Double-Blind Comparison of the Nephrotoxicity and Auditory Toxicity of Gentamicin and Tobramycin
Smith, Craig R, Lipsky, James J, Laskin, Oscar L, Hellmann, David B, Mellits, E. David, Longstreth, James, Lietman, Paul S
Published in The New England journal of medicine (15.05.1980)
Published in The New England journal of medicine (15.05.1980)
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Journal Article
Ribavirin disposition in high-risk patients for acquired immunodeficiency syndrome
Laskin, O L, Longstreth, J A, Hart, C C, Scavuzzo, D, Kalman, C M, Connor, J D, Roberts, R B
Published in Clinical pharmacology and therapeutics (01.05.1987)
Published in Clinical pharmacology and therapeutics (01.05.1987)
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