Design and synthesis of novel quinazolinone-chalcone hybrids as potential apoptotic candidates targeting caspase-3 and PARP-1: in vitro, molecular docking, and SAR studies
Madbouly, Eman A., Lashine, El-Sayed M., Al-Karmalawy, Ahmed A., Sebaiy, Mahmoud M., Pratsinis, Harris, Kletsas, Dimitris, Metwally, Kamel
Published in New journal of chemistry (28.11.2022)
Published in New journal of chemistry (28.11.2022)
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Design, synthesis and biological evaluation of novel quinazoline-2,4-diones conjugated with different amino acids as potential chitin synthase inhibitors
Noureldin, Nada A., Kothayer, Hend, Lashine, El-Sayed M., Baraka, Mohamed M., Huang, Yanrong, Li, Bing, Ji, Qinggang
Published in European journal of medicinal chemistry (25.05.2018)
Published in European journal of medicinal chemistry (25.05.2018)
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Hydrazones of 2-aryl-quinoline-4-carboxylic acid hydrazides: Synthesis and preliminary evaluation as antimicrobial agents
Metwally, Kamel A., Abdel-Aziz, Lobna M., Lashine, El-Sayed M., Husseiny, Mohamed I., Badawy, Rania H.
Published in Bioorganic & medicinal chemistry (15.12.2006)
Published in Bioorganic & medicinal chemistry (15.12.2006)
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Exploring the binding sites of Staphylococcus aureus phenylalanine tRNA synthetase: A homology model approach
Elbaramawi, Samar S., Ibrahim, Samy M., Lashine, El-Sayed M., El-Sadek, Mohamed E., Mantzourani, Efi, Simons, Claire
Published in Journal of molecular graphics & modelling (01.05.2017)
Published in Journal of molecular graphics & modelling (01.05.2017)
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Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives
Eissa, Ahmed G., Blaxland, James A., Williams, Rhodri O., Metwally, Kamel A., El-Adl, Sobhy M., Lashine, El-Sayed M., Baillie, Leslie W. J., Simons, Claire
Published in Journal of enzyme inhibition and medicinal chemistry (01.11.2016)
Published in Journal of enzyme inhibition and medicinal chemistry (01.11.2016)
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Design, Synthesis and Microbiological Evaluation of Novel Compounds as Potential Staphylococcus aureus Phenylalanine tRNA Synthetase Inhibitors
Elbaramawi, Samar S, Hughes, Casey, Richards, Jennifer, Gupta, Arya, Ibrahim, Samy M, Lashine, El-Sayed M, El-Sadek, Mohamed E, O'Neill, Alex J, Wootton, Mandy, Bullard, James M, Simons, Claire
Published in Egyptian journal of chemistry (01.11.2018)
Published in Egyptian journal of chemistry (01.11.2018)
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Non-carboxylic analogues of arylpropionic acids: Synthesis, anti-inflammatory activity and ulcerogenic potential
Metwally, Kamel A., Yaseen, Shada H., Lashine, El-Sayed M., El-Fayomi, Hassan M., El-Sadek, Mohamed E.
Published in European journal of medicinal chemistry (01.02.2007)
Published in European journal of medicinal chemistry (01.02.2007)
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Synthesis and Biological Evaluation of the Anti-Inflammatory Activity for some Novel Oxpholipin-11D Analogues
Lashine, El-Sayed M., Haikal, Abdel Fattah, Kul, Mansour E. Abou, Nasrallah, Lina A., Naglah, Ahmed M.
Published in International journal of pharmacology (15.09.2015)
Published in International journal of pharmacology (15.09.2015)
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Adenine and benzimidazole-based mimics of REP-3123 as antibacterial agents against Clostridium difficile and Bacillus anthracis: Design, synthesis and biological evaluation
Eissa, Ahmed G., Blaxland, James A., Williams, Rhodri O., Metwally, Kamel A., El-Adl, Sobhy M., Lashine, El-Sayed M., Baillie, Leslie W.J., Simons, Claire
Published in Bulletin of the Faculty of Pharmacy (01.12.2016)
Published in Bulletin of the Faculty of Pharmacy (01.12.2016)
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Design and synthesis of novel quinazolinone-chalcone hybrids as potential apoptotic candidates targeting caspase-3 and PARP-1: , molecular docking, and SAR studies
Madbouly, Eman A, Lashine, El-Sayed M, Al-Karmalawy, Ahmed A, Sebaiy, Mahmoud M, Pratsinis, Harris, Kletsas, Dimitris, Metwally, Kamel
Published in New journal of chemistry (28.11.2022)
Published in New journal of chemistry (28.11.2022)
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Journal Article