Transmission of malaria to mosquitoes blocked by bumped kinase inhibitors
Ojo, Kayode K, Pfander, Claudia, Mueller, Natascha R, Burstroem, Charlotte, Larson, Eric T, Bryan, Cassie M, Fox, Anna M W, Reid, Molly C, Johnson, Steven M, Murphy, Ryan C, Kennedy, Mark, Mann, Henning, Leibly, David J, Hewitt, Stephen N, Verlinde, Christophe L M J, Kappe, Stefan, Merritt, Ethan A, Maly, Dustin J, Billker, Oliver, Van Voorhis, Wesley C
Published in The Journal of clinical investigation (01.06.2012)
Published in The Journal of clinical investigation (01.06.2012)
Get full text
Journal Article
Structure of an Archaeal Virus Capsid Protein Reveals a Common Ancestry to Eukaryotic and Bacterial Viruses
Reza Khayat, Tang, Liang, Eric T. Larson, Lawrence, C. Martin, Young, Mark, Johnson, John E.
Published in Proceedings of the National Academy of Sciences - PNAS (27.12.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (27.12.2005)
Get full text
Journal Article
Active site profiling reveals coupling between domains in SRC-family kinases
Krishnamurty, Ratika, Brigham, Jennifer L, Leonard, Stephen E, Ranjitkar, Pratistha, Larson, Eric T, Dale, Edward J, Merritt, Ethan A, Maly, Dustin J
Published in Nature chemical biology (01.01.2013)
Published in Nature chemical biology (01.01.2013)
Get full text
Journal Article
Structural basis for type VI secretion effector recognition by a cognate immunity protein
Li, Mo, Le Trong, Isolde, Carl, Mike A, Larson, Eric T, Chou, Seemay, De Leon, Justin A, Dove, Simon L, Stenkamp, Ronald E, Mougous, Joseph D
Published in PLoS pathogens (01.04.2012)
Published in PLoS pathogens (01.04.2012)
Get full text
Journal Article
Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1
Larson, Eric T, Ojo, Kayode K, Murphy, Ryan C, Johnson, Steven M, Zhang, Zhongsheng, Kim, Jessica E, Leibly, David J, Fox, Anna M. W, Reid, Molly C, Dale, Edward J, Perera, B. Gayani K, Kim, Jae, Hewitt, Stephen N, Hol, Wim G. J, Verlinde, Christophe L. M. J, Fan, Erkang, Van Voorhis, Wesley C, Maly, Dustin J, Merritt, Ethan A
Published in Journal of medicinal chemistry (22.03.2012)
Published in Journal of medicinal chemistry (22.03.2012)
Get full text
Journal Article
Toxoplasma gondii Cathepsin L Is the Primary Target of the Invasion-inhibitory Compound Morpholinurea-leucyl-homophenyl-vinyl Sulfone Phenyl
Larson, Eric T., Parussini, Fabiola, Huynh, My-Hang, Giebel, Jonathan D., Kelley, Angela M., Zhang, Li, Bogyo, Matthew, Merritt, Ethan A., Carruthers, Vern B.
Published in The Journal of biological chemistry (25.09.2009)
Published in The Journal of biological chemistry (25.09.2009)
Get full text
Journal Article
A winged-helix protein from sulfolobus turreted icosahedral virus points toward stabilizing disulfide bonds in the intracellular proteins of a hyperthermophilic virus
Larson, Eric T, Eilers, Brian, Menon, Smita, Reiter, Dirk, Ortmann, Alice, Young, Mark J, Lawrence, C. Martin
Published in Virology (New York, N.Y.) (25.11.2007)
Published in Virology (New York, N.Y.) (25.11.2007)
Get full text
Journal Article
Prediction of protein crystallization outcome using a hybrid method
Zucker, Frank H., Stewart, Christine, Rosa, Jaclyn dela, Kim, Jessica, Zhang, Li, Xiao, Liren, Ross, Jenni, Napuli, Alberto J., Mueller, Natascha, Castaneda, Lisa J., Nakazawa Hewitt, Stephen R., Arakaki, Tracy L., Larson, Eric T., Subramanian, Easwara, Verlinde, Christophe L.M.J., Fan, Erkang, Buckner, Frederick S., Van Voorhis, Wesley C., Merritt, Ethan A., Hol, Wim G.J.
Published in Journal of structural biology (01.07.2010)
Published in Journal of structural biology (01.07.2010)
Get full text
Journal Article
X‐ray crystal structure localizes the mechanism of inhibition of an IL‐36R antagonist monoclonal antibody to interaction with Ig1 and Ig2 extra cellular domains
Larson, Eric T., Brennan, Debra L., Hickey, Eugene R., Ganesan, Raj, Kroe‐Barrett, Rachel, Farrow, Neil A.
Published in Protein science (01.07.2020)
Published in Protein science (01.07.2020)
Get full text
Journal Article
Development of Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitors with Potent Anti-Toxoplasma Activity
Johnson, Steven M, Murphy, Ryan C, Geiger, Jennifer A, DeRocher, Amy E, Zhang, Zhongsheng, Ojo, Kayode K, Larson, Eric T, Perera, B. Gayani K, Dale, Edward J, He, Panqing, Reid, Molly C, Fox, Anna M. W, Mueller, Natascha R, Merritt, Ethan A, Fan, Erkang, Parsons, Marilyn, Van Voorhis, Wesley C, Maly, Dustin J
Published in Journal of medicinal chemistry (08.03.2012)
Published in Journal of medicinal chemistry (08.03.2012)
Get full text
Journal Article
Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors
Ojo, Kayode K, Larson, Eric T, Keyloun, Katelyn R, Castaneda, Lisa J, DeRocher, Amy E, Inampudi, Krishna K, Kim, Jessica E, Arakaki, Tracy L, Murphy, Ryan C, Zhang, Li, Napuli, Alberto J, Maly, Dustin J, Verlinde, Christophe L M J, Buckner, Frederick S, Parsons, Marilyn, Hol, Wim G J, Merritt, Ethan A, Van Voorhis, Wesley C
Published in Nature structural & molecular biology (01.05.2010)
Published in Nature structural & molecular biology (01.05.2010)
Get full text
Journal Article
Inexpensive robotic system for standard and fluorescent imaging of protein crystals
Handzlik, Dakota, Larson, Eric T., Munschy, Erika, Obmolova, Galina, Collin, Delphine, Craig, Timothy K.
Published in Acta crystallographica. Section F, Structural biology communications (01.11.2019)
Published in Acta crystallographica. Section F, Structural biology communications (01.11.2019)
Get full text
Journal Article
Affinity-Based Probes Based on Type II Kinase Inhibitors
Ranjitkar, Pratistha, Perera, B. Gayani K, Swaney, Daniel L, Hari, Sanjay B, Larson, Eric T, Krishnamurty, Ratika, Merritt, Ethan A, Villén, Judit, Maly, Dustin J
Published in Journal of the American Chemical Society (21.11.2012)
Published in Journal of the American Chemical Society (21.11.2012)
Get full text
Journal Article
Monitoring GAPDH activity and inhibition with cysteine-reactive chemical probes
Canarelli, Sarah E, Swalm, Brooke M, Larson, Eric T, Morrison, Michael J, Weerapana, Eranthie
Published in RSC chemical biology (06.07.2022)
Published in RSC chemical biology (06.07.2022)
Get full text
Journal Article
Discovery of Potent and Selective Inhibitors of CDPK1 from C. parvum and T. gondii
Murphy, Ryan C, Ojo, Kayode K, Larson, Eric T, Castellanos-Gonzalez, Alejandro, Perera, B. Gayani K, Keyloun, Katelyn R, Kim, Jessica E, Bhandari, Janhavi G, Muller, Natascha R, Verlinde, Christophe L. M. J, White, A. Clinton, Merritt, Ethan A, Van Voorhis, Wesley C, Maly, Dustin J
Published in ACS medicinal chemistry letters (14.10.2010)
Published in ACS medicinal chemistry letters (14.10.2010)
Get full text
Journal Article
Benzoylbenzimidazole-based selective inhibitors targeting Cryptosporidium parvum and Toxoplasma gondii calcium-dependent protein kinase-1
Zhang, Zhongsheng, Ojo, Kayode K., Johnson, Steven M., Larson, Eric T., He, Penqing, Geiger, Jennifer A., Castellanos-Gonzalez, Alejandro, White, A. Clinton, Parsons, Marilyn, Merritt, Ethan A., Maly, Dustin J., Verlinde, Christophe L.M.J., Van Voorhis, Wesley C., Fan, Erkang
Published in Bioorganic & medicinal chemistry letters (15.08.2012)
Published in Bioorganic & medicinal chemistry letters (15.08.2012)
Get full text
Journal Article
Structure of Leishmania major methionyl-tRNA synthetase in complex with intermediate products methionyladenylate and pyrophosphate
Larson, Eric T., Kim, Jessica E., Zucker, Frank H., Kelley, Angela, Mueller, Natascha, Napuli, Alberto J., Verlinde, Christophe L.M.J., Fan, Erkang, Buckner, Frederick S., Van Voorhis, Wesley C., Merritt, Ethan A., Hol, Wim G.J.
Published in Biochimie (01.03.2011)
Published in Biochimie (01.03.2011)
Get full text
Journal Article
The Double-Length Tyrosyl-tRNA Synthetase from the Eukaryote Leishmania major Forms an Intrinsically Asymmetric Pseudo-Dimer
Larson, Eric T., Kim, Jessica E., Castaneda, Lisa J., Napuli, Alberto J., Zhang, Zhongsheng, Fan, Erkang, Zucker, Frank H., Verlinde, Christophe L.M.J., Buckner, Frederick S., Van Voorhis, Wesley C., Hol, Wim G.J., Merritt, Ethan A.
Published in Journal of molecular biology (03.06.2011)
Published in Journal of molecular biology (03.06.2011)
Get full text
Journal Article
Crystal Structures of Trypanosomal Histidyl-tRNA Synthetase Illuminate Differences between Eukaryotic and Prokaryotic Homologs
Merritt, Ethan A., Arakaki, Tracy L., Gillespie, J. Robert, Larson, Eric T., Kelley, Angela, Mueller, Natascha, Napuli, Alberto J., Kim, Jessica, Zhang, Li, Verlinde, Christophe L.M.J., Fan, Erkang, Zucker, Frank, Buckner, Frederick S., Van Voorhis, Wesley C., Hol, Wim G.J.
Published in Journal of molecular biology (26.03.2010)
Published in Journal of molecular biology (26.03.2010)
Get full text
Journal Article