APR-246 induces early cell death by ferroptosis in acute myeloid leukemia
Birsen, Rudy, Larrue, Clement, Decroocq, Justine, Johnson, Natacha, Guiraud, Nathan, Gotanegre, Mathilde, Cantero-Aguilar, Lilia, Grignano, Eric, Huynh, Tony, Fontenay, Michaela, Kosmider, Olivier, Mayeux, Patrick, Chapuis, Nicolas, Sarry, Jean Emmanuel, Tamburini, Jerome, Bouscary, Didier
Published in Haematologica (Roma) (01.02.2022)
Published in Haematologica (Roma) (01.02.2022)
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CD36 drives metastasis and relapse in acute myeloid leukemia
Farge, Thomas, Nakhle, Jean, Lagarde, Damien, Cognet, Guillaume, Polley, Nathaniel, Castellano, Remy, Nicolau, Marie-Laure, Bosc, Claudie, Sabatier, Marie, Sahal, Ambrine, Saland, Estelle, Jeanson, Yannick, Guiraud, Nathan, Boet, Emeline, Bergoglio, Camille, Gotanègre, Mathilde, Mouchel, Pierre-Luc, Stuani, Lucille, Larrue, Clement, Sallese, Marie, De Mas, Véronique, Moro, Cédric, Dray, Cedric, Collette, Yves, Raymond-Letron, Isabelle, Ader, Isabelle, Recher, Christian, Sarry, Jean-Emmanuel, Cabon, Florence, Vergez, Francois, Carriere, Audrey
Published in Cancer research (Chicago, Ill.) (01.09.2023)
Published in Cancer research (Chicago, Ill.) (01.09.2023)
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Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy
Marone, Romina, Landmann, Emmanuelle, Devaux, Anna, Lepore, Rosalba, Seyres, Denis, Zuin, Jessica, Burgold, Thomas, Engdahl, Corinne, Capoferri, Giuseppina, Dell'Aglio, Alessandro, Larrue, Clément, Simonetta, Federico, Rositzka, Julia, Rhiel, Manuel, Andrieux, Geoffroy, Gallagher, Danielle N, Schröder, Markus S, Wiederkehr, Amélie, Sinopoli, Alessandro, Do Sacramento, Valentin, Haydn, Anna, Garcia-Prat, Laura, Divsalar, Christopher, Camus, Anna, Xu, Liwen, Bordoli, Lorenza, Schwede, Torsten, Porteus, Matthew, Tamburini, Jérôme, Corn, Jacob E, Cathomen, Toni, Cornu, Tatjana I, Urlinger, Stefanie, Jeker, Lukas T
Published in The Journal of experimental medicine (04.12.2023)
Published in The Journal of experimental medicine (04.12.2023)
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Extracellular ATP and CD39 Activate cAMP-Mediated Mitochondrial Stress Response to Promote Cytarabine Resistance in Acute Myeloid Leukemia
Aroua, Nesrine, Boet, Emeline, Ghisi, Margherita, Nicolau-Travers, Marie-Laure, Saland, Estelle, Gwilliam, Ryan, de Toni, Fabienne, Hosseini, Mohsen, Mouchel, Pierre-Luc, Farge, Thomas, Bosc, Claudie, Stuani, Lucille, Sabatier, Marie, Mazed, Fetta, Larrue, Clément, Jarrou, Latifa, Gandarillas, Sarah, Bardotti, Massimiliano, Picard, Muriel, Syrykh, Charlotte, Laurent, Camille, Gotanègre, Mathilde, Bonnefoy, Nathalie, Bellvert, Floriant, Portais, Jean-Charles, Nicot, Nathalie, Azuaje, Francisco, Kaoma, Tony, Joffre, Carine, Tamburini, Jérome, Récher, Christian, Vergez, François, Sarry, Jean-Emmanuel
Published in Cancer discovery (01.10.2020)
Published in Cancer discovery (01.10.2020)
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AMP-Activated Protein Kinase Contributes to Apoptosis Induced by the Bcl-2 Inhibitor Venetoclax in Acute Myeloid Leukemia
Legrand, Noémie, Pradier, Amandine, Poulain, Laury, Mouche, Sarah, Birsen, Rudy, Larrue, Clément, Simonetta, Federico, Tamburini, Jerome
Published in Cancers (27.11.2021)
Published in Cancers (27.11.2021)
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Antileukemic Activity of 2-Deoxy-d-Glucose through Inhibition of N-Linked Glycosylation in Acute Myeloid Leukemia with FLT3-ITD or c-KIT Mutations
Larrue, Clément, Saland, Estelle, Vergez, François, Serhan, Nizar, Delabesse, Eric, Mansat-De Mas, Véronique, Hospital, Marie-Anne, Tamburini, Jérôme, Manenti, Stéphane, Sarry, Jean Emmanuel, Récher, Christian
Published in Molecular cancer therapeutics (01.10.2015)
Published in Molecular cancer therapeutics (01.10.2015)
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CDC25A governs proliferation and differentiation of FLT3-ITD acute myeloid leukemia
Bertoli, Sarah, Boutzen, Helena, David, Laure, Larrue, Clément, Vergez, François, Fernandez-Vidal, Anne, Yuan, Lingli, Hospital, Marie-Anne, Tamburini, Jérôme, Demur, Cécile, Delabesse, Eric, Saland, Estelle, Sarry, Jean-Emmanuel, Galcera, Marie-Odile, Mansat-De Mas, Véronique, Didier, Christine, Dozier, Christine, Récher, Christian, Manenti, Stéphane
Published in Oncotarget (10.11.2015)
Published in Oncotarget (10.11.2015)
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Proteasome inhibitors induce FLT3-ITD degradation through autophagy in AML cells
Larrue, Clément, Saland, Estelle, Boutzen, Héléna, Vergez, François, David, Marion, Joffre, Carine, Hospital, Marie-Anne, Tamburini, Jérôme, Delabesse, Eric, Manenti, Stéphane, Sarry, Jean Emmanuel, Récher, Christian
Published in Blood (18.02.2016)
Published in Blood (18.02.2016)
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Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites
Bosc, Claudie, Broin, Nicolas, Fanjul, Marjorie, Saland, Estelle, Farge, Thomas, Courdy, Charly, Batut, Aurélie, Masoud, Rawand, Larrue, Clément, Skuli, Sarah, Espagnolle, Nicolas, Pagès, Jean-Christophe, Carrier, Alice, Bost, Frédéric, Bertrand-Michel, Justine, Tamburini, Jérôme, Récher, Christian, Bertoli, Sarah, Mansat-De Mas, Véronique, Manenti, Stéphane, Sarry, Jean-Emmanuel, Joffre, Carine
Published in Nature communications (13.08.2020)
Published in Nature communications (13.08.2020)
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Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition
Jacque, Nathalie, Ronchetti, Anne Marie, Larrue, Clément, Meunier, Godelieve, Birsen, Rudy, Willems, Lise, Saland, Estelle, Decroocq, Justine, Maciel, Thiago Trovati, Lambert, Mireille, Poulain, Laury, Hospital, Marie Anne, Sujobert, Pierre, Joseph, Laure, Chapuis, Nicolas, Lacombe, Catherine, Moura, Ivan Cruz, Demo, Susan, Sarry, Jean Emmanuel, Recher, Christian, Mayeux, Patrick, Tamburini, Jérôme, Bouscary, Didier
Published in Blood (10.09.2015)
Published in Blood (10.09.2015)
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An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML
Lin, Shan, Larrue, Clément, Scheidegger, Nastassja K, Seong, Bo Kyung A, Dharia, Neekesh V, Kuljanin, Miljan, Wechsler, Caroline S, Kugener, Guillaume, Robichaud, Amanda L, Conway, Amy Saur, Mashaka, Thelma, Mouche, Sarah, Adane, Biniam, Ryan, Jeremy A, Mancias, Joseph D, Younger, Scott T, Piccioni, Federica, Lee, Lynn H, Wunderlich, Mark, Letai, Anthony, Tamburini, Jérôme, Stegmaier, Kimberly
Published in Cancer discovery (01.02.2022)
Published in Cancer discovery (01.02.2022)
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Targeting Myeloperoxidase Disrupts Mitochondrial Redox Balance and Overcomes Cytarabine Resistance in Human Acute Myeloid Leukemia
Hosseini, Mohsen, Rezvani, Hamid Reza, Aroua, Nesrine, Bosc, Claudie, Farge, Thomas, Saland, Estelle, Guyonnet-Dupérat, Véronique, Zaghdoudi, Sonia, Jarrou, Latifa, Larrue, Clément, Sabatier, Marie, Mouchel, Pierre Luc, Gotanègre, Mathilde, Piechaczyk, Marc, Bossis, Guillaume, Récher, Christian, Sarry, Jean-Emmanuel
Published in Cancer research (Chicago, Ill.) (15.10.2019)
Published in Cancer research (Chicago, Ill.) (15.10.2019)
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Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells
Larrue, Clément, Guiraud, Nathan, Mouchel, Pierre-Luc, Dubois, Marine, Farge, Thomas, Gotanègre, Mathilde, Bosc, Claudie, Saland, Estelle, Nicolau-Travers, Marie-Laure, Sabatier, Marie, Serhan, Nizar, Sahal, Ambrine, Boet, Emeline, Mouche, Sarah, Heydt, Quentin, Aroua, Nesrine, Stuani, Lucille, Kaoma, Tony, Angenendt, Linus, Mikesch, Jan-Henrik, Schliemann, Christoph, Vergez, François, Tamburini, Jérôme, Récher, Christian, Sarry, Jean-Emmanuel
Published in Nature communications (18.01.2021)
Published in Nature communications (18.01.2021)
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Dexamethasone in hyperleukocytic acute myeloid leukemia
Bertoli, Sarah, Picard, Muriel, Bérard, Emilie, Griessinger, Emmanuel, Larrue, Clément, Mouchel, Pierre Luc, Vergez, François, Tavitian, Suzanne, Yon, Edwige, Ruiz, Jean, Delabesse, Eric, Luquet, Isabelle, Linares, Laetitia Karine, Saland, Estelle, Carroll, Martin, Danet-Desnoyers, Gwenn, Sarry, Audrey, Huguet, Françoise, Sarry, Jean Emmanuel, Récher, Christian
Published in Haematologica (Roma) (01.06.2018)
Published in Haematologica (Roma) (01.06.2018)
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CHK1 as a therapeutic target to bypass chemoresistance in AML
David, Laure, Fernandez-Vidal, Anne, Bertoli, Sarah, Grgurevic, Srdana, Lepage, Benoît, Deshaies, Dominique, Prade, Naïs, Cartel, Maëlle, Larrue, Clément, Sarry, Jean-Emmanuel, Delabesse, Eric, Cazaux, Christophe, Didier, Christine, Récher, Christian, Manenti, Stéphane, Hoffmann, Jean-Sébastien
Published in Science signaling (13.09.2016)
Published in Science signaling (13.09.2016)
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Ferritin heavy/light chain (FTH1/FTL) expression, serum ferritin levels, and their functional as well as prognostic roles in acute myeloid leukemia
Bertoli, Sarah, Paubelle, Etienne, Bérard, Emilie, Saland, Estelle, Thomas, Xavier, Tavitian, Suzanne, Larcher, Marie‐Virginie, Vergez, François, Delabesse, Eric, Sarry, Audrey, Huguet, Françoise, Larrue, Clément, Bosc, Claudie, Farge, Thomas, Sarry, Jean Emmanuel, Michallet, Mauricette, Récher, Christian
Published in European journal of haematology (01.02.2019)
Published in European journal of haematology (01.02.2019)
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Dendrogenin A drives LXR to trigger lethal autophagy in cancers
Segala, Gregory, David, Marion, de Medina, Philippe, Poirot, Mathias C., Serhan, Nizar, Vergez, François, Mougel, Aurelie, Saland, Estelle, Carayon, Kevin, Leignadier, Julie, Caron, Nicolas, Voisin, Maud, Cherier, Julia, Ligat, Laetitia, Lopez, Frederic, Noguer, Emmanuel, Rives, Arnaud, Payré, Bruno, Saati, Talal al, Lamaziere, Antonin, Despres, Gaëtan, Lobaccaro, Jean-Marc, Baron, Silvere, Demur, Cecile, de Toni, Fabienne, Larrue, Clément, Boutzen, Helena, Thomas, Fabienne, Sarry, Jean-Emmanuel, Tosolini, Marie, Picard, Didier, Record, Michel, Récher, Christian, Poirot, Marc, Silvente-Poirot, Sandrine
Published in Nature communications (04.12.2017)
Published in Nature communications (04.12.2017)
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Selective haematological cancer eradication with preserved haematopoiesis
Garaudé, Simon, Marone, Romina, Lepore, Rosalba, Devaux, Anna, Beerlage, Astrid, Seyres, Denis, Dell’ Aglio, Alessandro, Juskevicius, Darius, Zuin, Jessica, Burgold, Thomas, Wang, Sisi, Katta, Varun, Manquen, Garret, Li, Yichao, Larrue, Clément, Camus, Anna, Durzynska, Izabela, Wellinger, Lisa C., Kirby, Ian, Van Berkel, Patrick H., Kunz, Christian, Tamburini, Jérôme, Bertoni, Francesco, Widmer, Corinne C., Tsai, Shengdar Q., Simonetta, Federico, Urlinger, Stefanie, Jeker, Lukas T.
Published in Nature (London) (20.06.2024)
Published in Nature (London) (20.06.2024)
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Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia
Boutzen, Héléna, Saland, Estelle, Larrue, Clément, de Toni, Fabienne, Gales, Lara, Castelli, Florence A, Cathebas, Mathilde, Zaghdoudi, Sonia, Stuani, Lucille, Kaoma, Tony, Riscal, Romain, Yang, Guangli, Hirsch, Pierre, David, Marion, De Mas-Mansat, Véronique, Delabesse, Eric, Vallar, Laurent, Delhommeau, François, Jouanin, Isabelle, Ouerfelli, Ouathek, Le Cam, Laurent, Linares, Laetitia K, Junot, Christophe, Portais, Jean-Charles, Vergez, François, Récher, Christian, Sarry, Jean-Emmanuel
Published in The Journal of experimental medicine (04.04.2016)
Published in The Journal of experimental medicine (04.04.2016)
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