Clinical importance of risk variants in the dihydropyrimidine dehydrogenase gene for the prediction of early‐onset fluoropyrimidine toxicity
Froehlich, Tanja K., Amstutz, Ursula, Aebi, Stefan, Joerger, Markus, Largiadèr, Carlo R.
Published in International journal of cancer (01.02.2015)
Published in International journal of cancer (01.02.2015)
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Using the PharmCAT tool for Pharmacogenetic clinical decision support
Tippenhauer, Kevin, Philips, Marwin, Largiadèr, Carlo, Sariyar, Murat
Published in Briefings in bioinformatics (22.11.2023)
Published in Briefings in bioinformatics (22.11.2023)
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Association of the Intestinal Microbiome with the Development of Neovascular Age-Related Macular Degeneration
Zinkernagel, Martin S, Zysset-Burri, Denise C, Keller, Irene, Berger, Lieselotte E, Leichtle, Alexander B, Largiadèr, Carlo R, Fiedler, Georg M, Wolf, Sebastian
Published in Scientific reports (17.01.2017)
Published in Scientific reports (17.01.2017)
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Annual incidence and severity of acute episodes in hereditary thrombotic thrombocytopenic purpura
Tarasco, Erika, Bütikofer, Lukas, Friedman, Kenneth D., George, James N., Hrachovinova, Ingrid, Knöbl, Paul N., Matsumoto, Masanori, von Krogh, Anne Sophie, Aebi-Huber, Isabella, Cermakova, Zuzana, Górska-Kosicka, Magdalena, Jalowiec, Katarzyna A., Largiadèr, Carlo R., Prohászka, Zoltán, Sinkovits, György, Windyga, Jerzy, Lämmle, Bernhard, Kremer Hovinga, Johanna A.
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Published in Blood (24.06.2021)
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Fluoropyrimidine chemotherapy: recommendations for DPYD genotyping and therapeutic drug monitoring of the Swiss Group of Pharmacogenomics and Personalised Therapy
Hamzic, Seid, Aebi, Stefan, Joerger, Markus, Montemurro, Michael, Ansari, Marc, Amstutz, Ursula, Largiadèr, Carlo
Published in Swiss medical weekly (24.11.2020)
Published in Swiss medical weekly (24.11.2020)
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Haplotype structure defines effects of common DPYD variants c.85T > C (rs1801265) and c.496A > G (rs2297595) on dihydropyrimidine dehydrogenase activity: Implication for 5‐fluorouracil toxicity
Hamzic, Seid, Schärer, Dominic, Offer, Steven M., Meulendijks, Didier, Nakas, Christos, Diasio, Robert B., Fontana, Stefano, Wehrli, Marc, Schürch, Stefan, Amstutz, Ursula, Largiadèr, Carlo R.
Published in British journal of clinical pharmacology (01.08.2021)
Published in British journal of clinical pharmacology (01.08.2021)
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The International Hereditary Thrombotic Thrombocytopenic Purpura Registry: key findings at enrollment until 2017
van Dorland, Hendrika A, Taleghani, Magnus Mansouri, Sakai, Kazuya, Friedman, Kenneth D, George, James N, Hrachovinova, Ingrid, Knöbl, Paul N, von Krogh, Anne Sophie, Schneppenheim, Reinhard, Aebi-Huber, Isabella, Bütikofer, Lukas, Largiadèr, Carlo R, Cermakova, Zuzana, Kokame, Koichi, Miyata, Toshiyuki, Yagi, Hideo, Terrell, Deirdra R, Vesely, Sara K, Matsumoto, Masanori, Lämmle, Bernhard, Fujimura, Yoshihiro, Kremer Hovinga, Johanna A
Published in Haematologica (Roma) (01.10.2019)
Published in Haematologica (Roma) (01.10.2019)
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LC-MS/MS method for simultaneous analysis of uracil, 5,6-dihydrouracil, 5-fluorouracil and 5-fluoro-5,6-dihydrouracil in human plasma for therapeutic drug monitoring and toxicity prediction in cancer patients
Büchel, Barbara, Rhyn, Peter, Schürch, Stefan, Bühr, Claudia, Amstutz, Ursula, R. Largiadèr, Carlo
Published in Biomedical chromatography (01.01.2013)
Published in Biomedical chromatography (01.01.2013)
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Determinants of Interpatient Variability in Treosulfan Pharmacokinetics in AML Patients Undergoing Autologous Stem Cell Transplantation
Ayçiçek, Selin G, Akhoundova, Dilara, Bacher, Ulrike, Hayoz, Michael, Aebi, Yolanda, Largiadèr, Carlo R, Pabst, Thomas
Published in International journal of molecular sciences (01.08.2024)
Published in International journal of molecular sciences (01.08.2024)
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Approach for Phased Sequence-Based Genotyping of the Critical Pharmacogene Dihydropyrimidine Dehydrogenase ( DPYD )
Ambrodji, Alisa, Sadlon, Angélique, Amstutz, Ursula, Hoch, Dennis, Berger, Martin D, Bastian, Sara, Offer, Steven M, Largiadèr, Carlo R
Published in International journal of molecular sciences (11.07.2024)
Published in International journal of molecular sciences (11.07.2024)
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The gut microbiome and HLA-B27-associated anterior uveitis: a case-control study
Morandi, Sophia C, Herzog, Elio L, Munk, Marion, Kreuzer, Marco, Largiadèr, Carlo R, Wolf, Sebastian, Zinkernagel, Martin, Zysset-Burri, Denise C
Published in Journal of neuroinflammation (07.05.2024)
Published in Journal of neuroinflammation (07.05.2024)
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Dihydropyrimidine Dehydrogenase Testing prior to Treatment with 5-Fluorouracil, Capecitabine, and Tegafur: A Consensus Paper
Wörmann, Bernhard, Bokemeyer, Carsten, Burmeister, Thomas, Köhne, Claus-Henning, Schwab, Matthias, Arnold, Dirk, Blohmer, Jens-Uwe, Borner, Markus, Brucker, Sara, Cascorbi, Ingolf, Decker, Thomas, de Wit, Maike, Dietz, Andreas, Einsele, Hermann, Eisterer, Wolfgang, Folprecht, Gunnar, Hilbe, Wolfgang, Hoffmann, Jürgen, Knauf, Wolfgang, Kunzmann, Volker, Largiadèr, Carlo R, Lorenzen, Sylvie, Lüftner, Diana, Moehler, Markus, Nöthen, Markus M, Pox, Christian, Reinacher-Schick, Anke, Scharl, Anton, Schlegelberger, Brigitte, Seufferlein, Thomas, Sinn, Marianne, Stroth, Matthias, Tamm, Ingo, Trümper, Lorenz, Wilhelm, Martin, Wöll, Ewald, Hofheinz, Ralf-Dieter
Published in Oncology research and treatment (01.11.2020)
Published in Oncology research and treatment (01.11.2020)
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Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data
Meulendijks, Didier, PharmD, Henricks, Linda M, PharmD, Sonke, Gabe S, MD, Deenen, Maarten J, PhD, Froehlich, Tanja K, PhD, Amstutz, Ursula, PhD, Largiadèr, Carlo R, Prof, Jennings, Barbara A, PhD, Marinaki, Anthony M, PhD, Sanderson, Jeremy D, MD, Kleibl, Zdenek, PhD, Kleiblova, Petra, PhD, Schwab, Matthias, Prof, Zanger, Ulrich M, Prof, Palles, Claire, PhD, Tomlinson, Ian, Prof, Gross, Eva, PhD, van Kuilenburg, André B P, PhD, Punt, Cornelis J A, Prof, Koopman, Miriam, MD, Beijnen, Jos H, Prof, Cats, Annemieke, MD, Schellens, Jan H M, Prof
Published in The lancet oncology (01.12.2015)
Published in The lancet oncology (01.12.2015)
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Increased erythroferrone levels in malarial anaemia
Neyer, Peter J., Kaboré, Bérenger, Nakas, Christos T., Diallo, Salou, Tinto, Halidou, Post, Annelies, Ven, Andre J., Huber, Andreas R., Largiadèr, Carlo R., Hammerer‐Lercher, Angelika
Published in British journal of haematology (01.05.2024)
Published in British journal of haematology (01.05.2024)
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Rs895819 in MIR27A improves the predictive value of DPYD variants to identify patients at risk of severe fluoropyrimidine‐associated toxicity
Meulendijks, Didier, Henricks, Linda M., Amstutz, Ursula, Froehlich, Tanja K., Largiadèr, Carlo R., Beijnen, Jos H., de Boer, Anthonius, Deenen, Maarten J., Cats, Annemieke, Schellens, Jan H.M.
Published in International journal of cancer (01.06.2016)
Published in International journal of cancer (01.06.2016)
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Serological testing for SARS‐CoV‐2 antibodies in clinical practice: A comparative diagnostic accuracy study
Horn, Michael P., Jonsdottir, Hulda R., Brigger, Daniel, Damonti, Lauro, Suter‐Riniker, Franziska, Endrich, Olga, Froehlich, Tanja K., Fiedler, Martin, Largiadèr, Carlo R., Marschall, Jonas, Weber, Benjamin, Eggel, Alexander, Nagler, Michael
Published in Allergy (Copenhagen) (01.07.2022)
Published in Allergy (Copenhagen) (01.07.2022)
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Comparison of methods for donor-derived cell-free DNA quantification in plasma and urine from solid organ transplant recipients
Kueng, Nicholas, Arcioni, Séverine, Sandberg, Fanny, Kuhn, Christian, Banz, Vanessa, Largiadèr, Carlo R, Sidler, Daniel, Amstutz, Ursula
Published in Frontiers in genetics (27.01.2023)
Published in Frontiers in genetics (27.01.2023)
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