Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors
Kosti, Paris, Opzoomer, James W., Larios-Martinez, Karen I., Henley-Smith, Rhonda, Scudamore, Cheryl L., Okesola, Mary, Taher, Mustafa Y.M., Davies, David M., Muliaditan, Tamara, Larcombe-Young, Daniel, Woodman, Natalie, Gillett, Cheryl E., Thavaraj, Selvam, Maher, John, Arnold, James N.
Published in Cell reports. Medicine (20.04.2021)
Published in Cell reports. Medicine (20.04.2021)
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Journal Article
Engineering of an Avidity-Optimized CD19-Specific Parallel Chimeric Antigen Receptor That Delivers Dual CD28 and 4-1BB Co-Stimulation
Halim, Leena, Das, Kushal K, Larcombe-Young, Daniel, Ajina, Adam, Candelli, Andrea, Benjamin, Reuben, Dillon, Richard, Davies, David M, Maher, John
Published in Frontiers in immunology (09.02.2022)
Published in Frontiers in immunology (09.02.2022)
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Journal Article
Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug Conjugates (ADCs)
Hoffmann, Ricarda M., Mele, Silvia, Cheung, Anthony, Larcombe-Young, Daniel, Bucaite, Gintare, Sachouli, Eirini, Zlatareva, Iva, Morad, Hassan O. J., Marlow, Rebecca, McDonnell, James M., Figini, Mariangela, Lacy, Katie E., Tutt, Andrew J. N., Spicer, James F., Thurston, David E., Karagiannis, Sophia N., Crescioli, Silvia
Published in Scientific reports (01.06.2020)
Published in Scientific reports (01.06.2020)
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Journal Article
PanErbB-targeted CAR T-cell immunotherapy of head and neck cancer
Larcombe-Young, Daniel, Papa, Sophie, Maher, John
Published in Expert opinion on biological therapy (01.09.2020)
Published in Expert opinion on biological therapy (01.09.2020)
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Journal Article
Anti-Folate Receptor Alpha-Directed Antibody Therapies Restrict the Growth of Triple-negative Breast Cancer
Cheung, Anthony, Opzoomer, James, Ilieva, Kristina M, Gazinska, Patrycja, Hoffmann, Ricarda M, Mirza, Hasan, Marlow, Rebecca, Francesch-Domenech, Erika, Fittall, Matthew, Dominguez Rodriguez, Diana, Clifford, Angela, Badder, Luned, Patel, Nirmesh, Mele, Silvia, Pellizzari, Giulia, Bax, Heather J, Crescioli, Silvia, Petranyi, Gyula, Larcombe-Young, Daniel, Josephs, Debra H, Canevari, Silvana, Figini, Mariangela, Pinder, Sarah, Nestle, Frank O, Gillett, Cheryl, Spicer, James F, Grigoriadis, Anita, Tutt, Andrew N J, Karagiannis, Sophia N
Published in Clinical cancer research (15.10.2018)
Published in Clinical cancer research (15.10.2018)
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Journal Article
Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors
Muliaditan, Tamara, Halim, Leena, Whilding, Lynsey M., Draper, Benjamin, Achkova, Daniela Y., Kausar, Fahima, Glover, Maya, Bechman, Natasha, Arulappu, Appitha, Sanchez, Jenifer, Flaherty, Katie R., Obajdin, Jana, Grigoriadis, Kristiana, Antoine, Pierre, Larcombe-Young, Daniel, Hull, Caroline M., Buus, Richard, Gordon, Peter, Grigoriadis, Anita, Davies, David M., Schurich, Anna, Maher, John
Published in Cell reports. Medicine (21.12.2021)
Published in Cell reports. Medicine (21.12.2021)
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Journal Article
Solid tumor immunotherapy using NKG2D-based adaptor CAR T cells
Obajdin, Jana, Larcombe-Young, Daniel, Glover, Maya, Kausar, Fahima, Hull, Caroline M., Flaherty, Katie R., Tan, Ge, Beatson, Richard E., Dunbar, Phoebe, Mazza, Roberta, Bove, Camilla, Taylor, Chelsea, Bille, Andrea, Spillane, Katelyn M., Cozzetto, Domenico, Vigilante, Alessandra, Schurich, Anna, Davies, David M., Maher, John
Published in Cell reports. Medicine (19.11.2024)
Published in Cell reports. Medicine (19.11.2024)
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Journal Article
CHIMERIC NKG2D PROTEIN
Larcombe-Young, Daniel, Maher, John, Davies, David Marc, Kausar, Fahima
Year of Publication 17.08.2023
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Year of Publication 17.08.2023
Patent
CHIMERIC NKG2D PROTEIN
MAHER, John, LARCOMBE-YOUNG, Daniel, DAVIES, David Marc, KAUSAR, Fahima
Year of Publication 29.03.2023
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Year of Publication 29.03.2023
Patent