Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion
Pradhan, Arnab, Avelar, Gabriela M., Bain, Judith M., Childers, Delma, Pelletier, Chloe, Larcombe, Daniel E., Shekhova, Elena, Netea, Mihai G., Brown, Gordon D., Erwig, Lars, Gow, Neil A. R., Brown, Alistair J. P.
Published in Nature communications (22.11.2019)
Published in Nature communications (22.11.2019)
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Rapid Identification of Clinically Relevant Members of the Genus Exophiala by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry and Description of Two Novel Species, Exophiala campbellii and Exophiala lavatrina
Borman, Andrew M, Fraser, Mark, Szekely, Adrien, Larcombe, Daniel E, Johnson, Elizabeth M
Published in Journal of clinical microbiology (01.04.2017)
Published in Journal of clinical microbiology (01.04.2017)
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Journal Article
Hypoxia Promotes Immune Evasion by Triggering β-Glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling
Pradhan, Arnab, Avelar, Gabriela M, Bain, Judith M, Childers, Delma S, Larcombe, Daniel E, Netea, Mihai G, Shekhova, Elena, Munro, Carol A, Brown, Gordon D, Erwig, Lars P, Gow, Neil A R, Brown, Alistair J P
Published in mBio (06.11.2018)
Published in mBio (06.11.2018)
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Journal Article
Epitope Shaving Promotes Fungal Immune Evasion
Childers, Delma S, Avelar, Gabriela Mol, Bain, Judith M, Pradhan, Arnab, Larcombe, Daniel E, Netea, Mihai G, Erwig, Lars P, Gow, Neil A R, Brown, Alistair J P
Published in mBio (07.07.2020)
Published in mBio (07.07.2020)
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Journal Article
Immune cells fold and damage fungal hyphae
Bain, Judith M., Alonso, M. Fernanda, Childers, Delma S., Walls, Catriona A., Mackenzie, Kevin, Pradhan, Arnab, Lewis, Leanne E., Louw, Johanna, Avelar, Gabriela M., Larcombe, Daniel E., Netea, Mihai G., Gow, Neil A. R., Brown, Gordon D., Erwig, Lars P., Brown, Alistair J. P.
Published in Proceedings of the National Academy of Sciences - PNAS (13.04.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (13.04.2021)
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Journal Article
Anticipatory Stress Responses and Immune Evasion in Fungal Pathogens
Pradhan, Arnab, Ma, Qinxi, de Assis, Leandro J., Leaves, Ian, Larcombe, Daniel E., Rodriguez Rondon, Alejandra V., Nev, Olga A., Brown, Alistair J.P.
Published in Trends in microbiology (Regular ed.) (01.05.2021)
Published in Trends in microbiology (Regular ed.) (01.05.2021)
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Journal Article
Nature of β-1,3-Glucan-Exposing Features on Candida albicans Cell Wall and Their Modulation
de Assis, Leandro José, Bain, Judith M, Liddle, Corin, Leaves, Ian, Hacker, Christian, Peres da Silva, Roberta, Yuecel, Raif, Bebes, Attila, Stead, David, Childers, Delma S, Pradhan, Arnab, Mackenzie, Kevin, Lagree, Katherine, Larcombe, Daniel E, Ma, Qinxi, Avelar, Gabriela Mol, Netea, Mihai G, Erwig, Lars P, Mitchell, Aaron P, Brown, Gordon D, Gow, Neil A R, Brown, Alistair J P
Published in mBio (20.12.2022)
Published in mBio (20.12.2022)
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Journal Article
A CO 2 sensing module modulates β-1,3-glucan exposure in Candida albicans
Avelar, Gabriela M, Pradhan, Arnab, Ma, Qinxi, Hickey, Emer, Leaves, Ian, Liddle, Corin, Rodriguez Rondon, Alejandra V, Kaune, Ann-Kristin, Shaw, Sophie, Maufrais, Corinne, Sertour, Natacha, Bain, Judith M, Larcombe, Daniel E, de Assis, Leandro J, Netea, Mihai G, Munro, Carol A, Childers, Delma S, Erwig, Lars P, Brown, Gordon D, Gow, Neil A R, Bougnoux, Marie-Elisabeth, d'Enfert, Christophe, Brown, Alistair J P
Published in mBio (14.02.2024)
Published in mBio (14.02.2024)
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Journal Article
A CO2 sensing module modulates β-1,3-glucan exposure in Candida albicans
Avelar, Gabriela M., Pradhan, Arnab, Ma, Qinxi, Hickey, Emer, Leaves, Ian, Liddle, Corin, Rodriguez Rondon, Alejandra V., Kaune, Ann-Kristin, Shaw, Sophie, Maufrais, Corinne, Sertour, Natacha, Bain, Judith M., Larcombe, Daniel E., de Assis, Leandro J., Netea, Mihai G., Munro, Carol A., Childers, Delma S., Erwig, Lars P., Brown, Gordon D., Gow, Neil A. R., Bougnoux, Marie-Elisabeth, d'Enfert, Christophe, Brown, Alistair J. P.
Published in mBio (14.02.2024)
Published in mBio (14.02.2024)
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Journal Article
Impact of the Environment upon the Candida albicans Cell Wall and Resultant Effects upon Immune Surveillance
Childers, Delma S, Avelar, Gabriela M, Bain, Judith M, Larcombe, Daniel E, Pradhan, Arnab, Budge, Susan, Heaney, Helen, Brown, Alistair J P
Published in Current topics in microbiology and immunology (01.01.2020)
Published in Current topics in microbiology and immunology (01.01.2020)
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Journal Article
Impact of secreted glucanases upon the cell surface and fitness of Candida albicans during colonisation and infection
Ma, Qinxi, Pradhan, Arnab, Leaves, Ian, Hickey, Emer, Roselletti, Elena, Dambuza, Ivy, Larcombe, Daniel E., de Assis, Leandro Jose, Wilson, Duncan, Erwig, Lars P., Netea, Mihai G., Childers, Delma S., Brown, Gordon D., Gow, Neil A.R., Brown, Alistair J.P.
Published in Cell surface (Amsterdam) (01.06.2024)
Published in Cell surface (Amsterdam) (01.06.2024)
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Journal Article
Impact of changes at the Candida albicans cell surface upon immunogenicity and colonisation in the gastrointestinal tract
Avelar, Gabriela M., Dambuza, Ivy M., Ricci, Liviana, Yuecel, Raif, Mackenzie, Kevin, Childers, Delma S., Bain, Judith M., Pradhan, Arnab, Larcombe, Daniel E., Netea, Mihai G., Erwig, Lars P., Brown, Gordon D., Duncan, Sylvia H., Gow, Neil A.R., Walker, Alan W., Brown, Alistair J.P.
Published in Cell surface (Amsterdam) (01.12.2022)
Published in Cell surface (Amsterdam) (01.12.2022)
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Journal Article
Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors
Kosti, Paris, Opzoomer, James W., Larios-Martinez, Karen I., Henley-Smith, Rhonda, Scudamore, Cheryl L., Okesola, Mary, Taher, Mustafa Y.M., Davies, David M., Muliaditan, Tamara, Larcombe-Young, Daniel, Woodman, Natalie, Gillett, Cheryl E., Thavaraj, Selvam, Maher, John, Arnold, James N.
Published in Cell reports. Medicine (20.04.2021)
Published in Cell reports. Medicine (20.04.2021)
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Journal Article
Glucose-enhanced oxidative stress resistance-A protective anticipatory response that enhances the fitness of Candida albicans during systemic infection
Larcombe, Daniel E, Bohovych, Iryna M, Pradhan, Arnab, Ma, Qinxi, Hickey, Emer, Leaves, Ian, Cameron, Gary, Avelar, Gabriela M, de Assis, Leandro J, Childers, Delma S, Bain, Judith M, Lagree, Katherine, Mitchell, Aaron P, Netea, Mihai G, Erwig, Lars P, Gow, Neil A R, Brown, Alistair J P
Published in PLoS pathogens (10.07.2023)
Published in PLoS pathogens (10.07.2023)
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Engineering of an Avidity-Optimized CD19-Specific Parallel Chimeric Antigen Receptor That Delivers Dual CD28 and 4-1BB Co-Stimulation
Halim, Leena, Das, Kushal K, Larcombe-Young, Daniel, Ajina, Adam, Candelli, Andrea, Benjamin, Reuben, Dillon, Richard, Davies, David M, Maher, John
Published in Frontiers in immunology (09.02.2022)
Published in Frontiers in immunology (09.02.2022)
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Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug Conjugates (ADCs)
Hoffmann, Ricarda M., Mele, Silvia, Cheung, Anthony, Larcombe-Young, Daniel, Bucaite, Gintare, Sachouli, Eirini, Zlatareva, Iva, Morad, Hassan O. J., Marlow, Rebecca, McDonnell, James M., Figini, Mariangela, Lacy, Katie E., Tutt, Andrew J. N., Spicer, James F., Thurston, David E., Karagiannis, Sophia N., Crescioli, Silvia
Published in Scientific reports (01.06.2020)
Published in Scientific reports (01.06.2020)
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