Deficiency in coatomer complex I causes aberrant activation of STING signalling
Steiner, Annemarie, Hrovat-Schaale, Katja, Prigione, Ignazia, Yu, Chien-Hsiung, Laohamonthonkul, Pawat, Harapas, Cassandra R., Low, Ronnie Ren Jie, De Nardo, Dominic, Dagley, Laura F., Mlodzianoski, Michael J., Rogers, Kelly L., Zillinger, Thomas, Hartmann, Gunther, Gantier, Michael P., Gattorno, Marco, Geyer, Matthias, Volpi, Stefano, Davidson, Sophia, Masters, Seth L.
Published in Nature communications (28.04.2022)
Published in Nature communications (28.04.2022)
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Journal Article
Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites
Lansink, Lianne I M, Skinner, Oliver P, Engel, Jessica A, Lee, Hyun Jae, Soon, Megan S F, Williams, Cameron G, SheelaNair, Arya, Pernold, Clara P S, Laohamonthonkul, Pawat, Akter, Jasmin, Stoll, Thomas, Hill, Michelle M, Talman, Arthur M, Russell, Andrew, Lawniczak, Mara, Jia, Xiaoxiao, Chua, Brendon, Anderson, Dovile, Creek, Darren J, Davenport, Miles P, Khoury, David S, Haque, Ashraful
Published in mBio (31.08.2023)
Published in mBio (31.08.2023)
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Journal Article
Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells
Akter, Jasmin, Khoury, David S, Aogo, Rosemary, Lansink, Lianne I M, SheelaNair, Arya, Thomas, Bryce S, Laohamonthonkul, Pawat, Pernold, Clara P S, Dixon, Matthew W A, Soon, Megan S F, Fogg, Lily G, Engel, Jessica A, Elliott, Trish, Sebina, Ismail, James, Kylie R, Cromer, Deborah, Davenport, Miles P, Haque, Ashraful
Published in PLoS pathogens (01.02.2019)
Published in PLoS pathogens (01.02.2019)
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Journal Article
Organellar homeostasis and innate immune sensing
Harapas, Cassandra R., Idiiatullina, Elina, Al-Azab, Mahmoud, Hrovat-Schaale, Katja, Reygaerts, Thomas, Steiner, Annemarie, Laohamonthonkul, Pawat, Davidson, Sophia, Yu, Chien-Hsiung, Booty, Lee, Masters, Seth L.
Published in Nature reviews. Immunology (01.09.2022)
Published in Nature reviews. Immunology (01.09.2022)
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Journal Article
Stray self-nucleic acids: the emerging drivers of neurodegeneration
McDonald, Brooke K., Laohamonthonkul, Pawat, Yu, Chien-Hsiung
Published in Trends in cell biology (01.06.2023)
Published in Trends in cell biology (01.06.2023)
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Journal Article
Pyrin variant E148Q potentiates inflammasome activation and the effect of pathogenic mutations in cis
Reygaerts, Thomas, Laohamonthonkul, Pawat, Hrovat-Schaale, Katja, Moghaddas, Fiona, Baker, Paul J, Gray, Paul E, Masters, Seth L
Published in Rheumatology (Oxford, England) (01.03.2024)
Published in Rheumatology (Oxford, England) (01.03.2024)
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Journal Article
Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain
Moecking, Jonas, Laohamonthonkul, Pawat, Meşe, Kubilay, Hagelueken, Gregor, Steiner, Annemarie, Harapas, Cassandra R., Sandow, Jarrod J., Graves, Jonathan D., Masters, Seth L., Geyer, Matthias
Published in The Journal of biological chemistry (01.12.2022)
Published in The Journal of biological chemistry (01.12.2022)
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Journal Article
Dominant negative OTULIN-related autoinflammatory syndrome
Davidson, Sophia, Shibata, Yuri, Collard, Sophie, Zheng, Hongyu, Kong, Klara, Sun, June M, Laohamonthonkul, Pawat, Cerra, Anthony, Kratina, Tobias, Li, Margaret W Y, Russell, Carolyn, van Beek, Anna, Kirk, Edwin P, Walsh, Rebecca, Alqanatish, Jubran, Almojali, Abdullah, Alsuwairi, Wafaa, Alrasheed, Abdulrahman, Lalaoui, Najoua, Gray, Paul E, Komander, David, Masters, Seth L
Published in The Journal of experimental medicine (03.06.2024)
Published in The Journal of experimental medicine (03.06.2024)
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Journal Article
Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory
Soon, Megan S. F., Lee, Hyun Jae, Engel, Jessica A., Straube, Jasmin, Thomas, Bryce S., Pernold, Clara P. S., Clarke, Lachlan S., Laohamonthonkul, Pawat, Haldar, Rohit N., Williams, Cameron G., Lansink, Lianne I. M., Moreira, Marcela L., Bramhall, Michael, Koufariotis, Lambros T., Wood, Scott, Chen, Xi, James, Kylie R., Lönnberg, Tapio, Lane, Steven W., Belz, Gabrielle T., Engwerda, Christian R., Khoury, David S., Davenport, Miles P., Svensson, Valentine, Teichmann, Sarah A., Haque, Ashraful
Published in Nature immunology (01.12.2020)
Published in Nature immunology (01.12.2020)
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Journal Article
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
Yu, Chien-Hsiung, Davidson, Sophia, Harapas, Cassandra R., Hilton, James B., Mlodzianoski, Michael J., Laohamonthonkul, Pawat, Louis, Cynthia, Low, Ronnie Ren Jie, Moecking, Jonas, De Nardo, Dominic, Balka, Katherine R., Calleja, Dale J., Moghaddas, Fiona, Ni, Erya, McLean, Catriona A., Samson, Andre L., Tyebji, Shiraz, Tonkin, Christopher J., Bye, Christopher R., Turner, Bradley J., Pepin, Genevieve, Gantier, Michael P., Rogers, Kelly L., McArthur, Kate, Crouch, Peter J., Masters, Seth L.
Published in Cell (29.10.2020)
Published in Cell (29.10.2020)
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Journal Article
NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity
Moecking, Jonas, Laohamonthonkul, Pawat, Chalker, Katelyn, White, Marquitta J., Harapas, Cassandra R., Yu, Chien-Hsiung, Davidson, Sophia, Hrovat-Schaale, Katja, Hu, Donglei, Eng, Celeste, Huntsman, Scott, Calleja, Dale J., Horvat, Jay C., Hansbro, Phil M., O’Donoghue, Robert J.J., Ting, Jenny P., Burchard, Esteban G., Geyer, Matthias, Gerlic, Motti, Masters, Seth L.
Published in Journal of allergy and clinical immunology (01.06.2021)
Published in Journal of allergy and clinical immunology (01.06.2021)
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Journal Article
Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24
Davidson, Sophia, Yu, Chien-Hsiung, Steiner, Annemarie, Ebstein, Frédéric, Baker, Paul J, Jarur-Chamy, Valentina, Hrovat Schaale, Katja, Laohamonthonkul, Pawat, Kong, Klara, Calleja, Dale J, Harapas, Cassandra R, Balka, Katherine R, Mitchell, Jacob, Jackson, Jacob T, Geoghegan, Niall D, Moghaddas, Fiona, Rogers, Kelly L, Mayer-Barber, Katrin D, De Jesus, Adriana A, De Nardo, Dominic, Kile, Benjamin T, Sadler, Anthony J, Poli, M Cecilia, Krüger, Elke, Goldbach Mansky, Raphaela, Masters, Seth L
Published in Science immunology (11.02.2022)
Published in Science immunology (11.02.2022)
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Quantification of host-mediated parasite clearance during blood-stage Plasmodium infection and anti-malarial drug treatment in mice
Aogo, Rosemary A., Khoury, David S., Cromer, Deborah, Elliott, Trish, Akter, Jasmin, Fogg, Lily G., Nair, Arya Sheela, Liligeto, Urijah N., Soon, Megan S.F., Thomas, Bryce S., Pernold, Clara P.S., Romanczuk, Aleksandra S., Laohamonthonkul, Pawat, Haque, Ashraful, Davenport, Miles P.
Published in International journal for parasitology (01.10.2018)
Published in International journal for parasitology (01.10.2018)
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Journal Article
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling
Harapas, Cassandra R, Robinson, Kim S, Lay, Kenneth, Wong, Jasmine, Moreno Traspas, Ricardo, Nabavizadeh, Nasrin, Rass-Rothschild, Annick, Boisson, Bertrand, Drutman, Scott B, Laohamonthonkul, Pawat, Bonner, Devon, Xiong, Jingwei Rachel, Gorrell, Mark D, Davidson, Sophia, Yu, Chien-Hsiung, Fleming, Mark D, Gudera, Jonas, Stein, Jerry, Ben-Harosh, Miriam, Groopman, Emily, Shimamura, Akiko, Tamary, Hannah, Kayserili, Hülya, Hatipoğlu, Nevin, Casanova, Jean-Laurent, Bernstein, Jonathan A, Zhong, Franklin L, Masters, Seth L, Reversade, Bruno
Published in Science immunology (16.09.2022)
Published in Science immunology (16.09.2022)
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Journal Article
Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites
Lianne Im Lansink, Engel, Jessica A, Lee, Hyun Jae, Soon, Megan Sf, Williams, Cameron G, Arya Sheelanair, Pernold, Clara P S, Laohamonthonkul, Pawat, Akter, Jasmin, Stoll, Thomas, Hill, Michelle M, Talman, Arthur M, Russell, Andrew J C, Lawniczak, Mara, Davenport, Miles P, Khoury, David S, Haque, Ashraful
Published in bioRxiv (19.08.2021)
Published in bioRxiv (19.08.2021)
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Activation of STING due to COPI-deficiency
Steiner, Annemarie, Katja Hrovat Schaale, Prigione, Ignazia, De Nardo, Dominic, Dagley, Laura F, Chien-Hsiung, Yu, Laohamonthonkul, Pawat, Harapas, Cassandra R, Gantier, Michael P, Gattorno, Marco, Volpi, Stefano, Davidson, Sophia, Masters, Seth L
Published in bioRxiv (09.07.2020)
Published in bioRxiv (09.07.2020)
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Transcriptome Dynamics Reveals Progressive Transition from Effector to Memory in CD4+ T cells
Soon, Megan S F, Lee, Hyun Jae, Engel, Jessica A, Straube, Jasmin, Thomas, Bryce S, Clarke, Lachlan S, Laohamonthonkul, Pawat, Pernold, Clara P S, Haldar, Rohit N, Williams, Cameron G, Lansink, Lianne I M, Ross Koufariotis, Lakis, Vanessa, Wood, Scott, Chen, Xi, James, Kylie R, Lönnberg, Tapio, Lane, Steven W, Davenport, Miles P, Khoury, David S, Svensson, Valentine, Teichmann, Sarah A, Haque, Ashraful
Published in bioRxiv (19.06.2019)
Published in bioRxiv (19.06.2019)
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